DK152115C - Analogifremgangsmaade til fremstilling af fluorerede 2,5-diamino-3-pentenderivater og farmaceutisk acceptable salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af fluorerede 2,5-diamino-3-pentenderivater og farmaceutisk acceptable salte deraf

Info

Publication number: DK152115C
Authority: DK; Denmark
Prior art keywords: pentende; fluorated; diamino; analogue; derivatives
Prior art date: 1980-08-23

Application number

DK372081A

Other languages

English (en)

Other versions

DK372081A (da

DK152115B (da

Inventor

Philippe Bey

Fritz Gerhart

Michel Jung

Original Assignee

Merrell Toraude & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-08-23

Filing date

1981-08-21

Publication date

1988-06-20

1981-08-21 Application filed by Merrell Toraude & Co filed Critical Merrell Toraude & Co

1982-02-24 Publication of DK372081A publication Critical patent/DK372081A/da

1988-02-01 Publication of DK152115B publication Critical patent/DK152115B/da

1988-06-20 Application granted granted Critical

1988-06-20 Publication of DK152115C publication Critical patent/DK152115C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

DK372081A 1980-08-23 1981-08-21 Analogifremgangsmaade til fremstilling af fluorerede 2,5-diamino-3-pentenderivater og farmaceutisk acceptable salte deraf DK152115C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB8027519		1980-08-23
GB8027519		1980-08-23
GB8037841		1980-11-26
GB8037841		1980-11-26

Publications (3)

Publication Number	Publication Date
DK372081A DK372081A (da)	1982-02-24
DK152115B DK152115B (da)	1988-02-01
DK152115C true DK152115C (da)	1988-06-20

Family

ID=26276683

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK372081A DK152115C (da)	1980-08-23	1981-08-21	Analogifremgangsmaade til fremstilling af fluorerede 2,5-diamino-3-pentenderivater og farmaceutisk acceptable salte deraf

Country Status (13)

Country	Link
US (1)	US4439619A (da)
EP (1)	EP0046713B1 (da)
AU (1)	AU544262B2 (da)
CA (1)	CA1182126A (da)
DE (1)	DE3173305D1 (da)
DK (1)	DK152115C (da)
ES (1)	ES504879A0 (da)
GB (1)	GB2083030B (da)
IE (1)	IE51511B1 (da)
IL (1)	IL63633A (da)
NO (1)	NO151196C (da)
NZ (1)	NZ198117A (da)
PH (1)	PH22945A (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4866206A (en) *	1977-07-11	1989-09-12	Merrell Dow France Et Cie	2-Halomethyl derivatives of 2-amino acids
US5614557A (en) *	1977-07-11	1997-03-25	Marion Merrell Et Compagnie C/O Merrell Pharmaceuticals Inc.	Method of controlling tumor growth rate
IE54303B1 (en) *	1981-08-19	1989-08-16	Merrell Dow France	Fluorinated diaminoalkene derivatives
US4435425A (en)	1982-04-09	1984-03-06	Merrell Toraude Et Compagnie	Fluorinated diaminobutane derivatives
US4629685A (en) *	1984-11-16	1986-12-16	Ciba-Geigy Corporation	Process for irradiating polyimides
US5196450A (en) *	1985-12-19	1993-03-23	Merrell Dow Pharmaceuticals Inc.	Method of inhibiting protozoal growth
DE3712364A1 (de) *	1987-04-11	1988-10-27	Hoechst Ag	Neue pyrrolidin-2-(1,3-dicarbonyl)-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung
DE3712365A1 (de) *	1987-04-11	1988-10-27	Hoechst Ag	Neue 2-acylpyrrolidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung
US20170273926A1 (en) *	2016-03-24	2017-09-28	Orbus Therapeutics, Inc.	Compositions and methods for use of eflornithine and derivatives and analogs thereof to treat cancers, including gliomas

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2662915A (en) *	1952-06-30	1953-12-15	Du Pont	Alpha-amino acids containing alpha, fluorinated-alkyl or cycloalkyl groups
US4325961A (en) *	1977-06-01	1982-04-20	Merck & Co., Inc.	Fluorinated amino acids
CA1091661A (en) *	1977-07-11	1980-12-16	Philippe Bey	.alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
US4134918A (en) *	1977-09-06	1979-01-16	Merrell Toraude Et Compagnie	Alpha-halomethyl derivatives of amines
US4326071A (en) *	1977-09-28	1982-04-20	Merrell Toraude Et Compagnie	Halomethyl derivatives of gamma-aminobutyric acid and related compounds
US4323704A (en) *	1979-06-25	1982-04-06	Merrell Toraude Et Compagnie	αAcetylene and α-vinyl derivatives of amino acids
NZ194348A (en) *	1979-07-26	1982-09-14	Merrell Toraude & Co	Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions

1981
- 1981-08-20 GB GB8125472A patent/GB2083030B/en not_active Expired
- 1981-08-21 US US06/295,152 patent/US4439619A/en not_active Expired - Lifetime
- 1981-08-21 EP EP81401330A patent/EP0046713B1/en not_active Expired
- 1981-08-21 PH PH26081A patent/PH22945A/en unknown
- 1981-08-21 NO NO812841A patent/NO151196C/no unknown
- 1981-08-21 ES ES504879A patent/ES504879A0/es active Granted
- 1981-08-21 DE DE8181401330T patent/DE3173305D1/de not_active Expired
- 1981-08-21 AU AU74432/81A patent/AU544262B2/en not_active Ceased
- 1981-08-21 IE IE1925/81A patent/IE51511B1/en not_active IP Right Cessation
- 1981-08-21 DK DK372081A patent/DK152115C/da not_active IP Right Cessation
- 1981-08-21 IL IL63633A patent/IL63633A/xx not_active IP Right Cessation
- 1981-08-21 CA CA000384357A patent/CA1182126A/en not_active Expired
- 1981-08-27 NZ NZ198117A patent/NZ198117A/en unknown

Also Published As

Publication number	Publication date
NO812841L (no)	1982-02-24
NO151196C (no)	1985-02-27
ES8306992A1 (es)	1983-06-16
GB2083030A (en)	1982-03-17
GB2083030B (en)	1984-03-07
IL63633A0 (en)	1981-11-30
IE51511B1 (en)	1987-01-07
DE3173305D1 (de)	1986-02-06
AU544262B2 (en)	1985-05-23
EP0046713A1 (en)	1982-03-03
DK372081A (da)	1982-02-24
ES504879A0 (es)	1983-06-16
IE811925L (en)	1982-05-23
EP0046713B1 (en)	1985-12-27
AU7443281A (en)	1982-03-04
IL63633A (en)	1985-05-31
NZ198117A (en)	1985-08-30
US4439619A (en)	1984-03-27
CA1182126A (en)	1985-02-05
NO151196B (no)	1984-11-19
DK152115B (da)	1988-02-01
PH22945A (en)	1989-02-03

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Legal Events

Date	Code	Title	Description
2001-04-17	PBP	Patent lapsed