DK149599C - Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf - Google Patents

Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf

Info

Publication number: DK149599C
Authority: DK; Denmark
Prior art keywords: trestatin; trestatina; salts; procedure; preparation
Prior art date: 1978-02-14

Application number

DK61179A

Other languages

Danish (da)

English (en)

Other versions

DK61179A (da

DK149599B (da

Inventor

Yasuji Suhara

Kiyoshi Ogawa

Kazuteru Yokose

Kimihiro Watanabe

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-02-14

Filing date

1979-02-13

Publication date

1987-06-01

1979-02-13 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1979-08-15 Publication of DK61179A publication Critical patent/DK61179A/da

1986-08-04 Publication of DK149599B publication Critical patent/DK149599B/da

1987-06-01 Application granted granted Critical

1987-06-01 Publication of DK149599C publication Critical patent/DK149599C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/99—Enzyme inactivation by chemical treatment
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
General Chemical & Material Sciences (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK61179A 1978-02-14 1979-02-13 Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf DK149599C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB583478		1978-02-14
GB583478		1978-02-14

Publications (3)

Publication Number	Publication Date
DK61179A DK61179A (da)	1979-08-15
DK149599B DK149599B (da)	1986-08-04
DK149599C true DK149599C (da)	1987-06-01

Family

ID=9803510

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK61179A DK149599C (da)	1978-02-14	1979-02-13	Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf

Country Status (26)

Country	Link
US (1)	US4273765A (es)
EP (1)	EP0003616B1 (es)
JP (1)	JPS54163511A (es)
AR (1)	AR219150A1 (es)
AT (1)	AT367451B (es)
AU (1)	AU527318B2 (es)
CA (1)	CA1121290A (es)
DE (2)	DE2905649A1 (es)
DK (1)	DK149599C (es)
ES (1)	ES477653A1 (es)
FI (1)	FI63062C (es)
FR (1)	FR2416901A1 (es)
GR (1)	GR72817B (es)
HU (1)	HU181442B (es)
IE (1)	IE47916B1 (es)
IL (1)	IL56626A0 (es)
LU (1)	LU80906A1 (es)
MC (1)	MC1253A1 (es)
NL (1)	NL7901182A (es)
NO (1)	NO153011C (es)
NZ (1)	NZ189625A (es)
PH (1)	PH15084A (es)
PT (1)	PT69218A (es)
SE (1)	SE7901276L (es)
YU (1)	YU41437B (es)
ZA (1)	ZA79528B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3166093D1 (en)	1981-01-05	1984-10-18	Takeda Chemical Industries Ltd	N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) *	1981-03-09	1982-09-10	Akira Endo	Hypoglycemic
US4595678A (en) *	1982-03-19	1986-06-17	Takeda Chemical Industries, Ltd.	N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4678812A (en) *	1986-05-30	1987-07-07	E. I. Du Pont De Nemours And Company	Trehalose as stabilizer and tableting excipient
US4762857A (en) *	1986-05-30	1988-08-09	E. I. Du Pont De Nemours And Company	Trehalose as stabilizer and tableting excipient
US4885361A (en) *	1987-07-31	1989-12-05	Hoffmann-La Roche Inc.	Sulfated oligosaccharides
JPH06503418A (ja) *	1990-11-30	1994-04-14	モノクロネティックス　インターナショナル、インコーポレーテッド	慢性下位脊椎痛および頚部痛の診断法
CA2128044C (en) *	1993-08-05	2007-02-20	Klaus-Dieter Bremer	Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
EP1157696B1 (en) *	2000-05-24	2006-10-25	Pfizer Limited	Treatment of rumen acidosis with alpha-amylase inhibitors
US7022684B2 (en) *	2000-05-24	2006-04-04	Pfizer Inc.	Treatment of rumen acidosis with α-amylase inhibitors
KR20060109926A (ko)	2003-11-19	2006-10-23	메타베이시스 테라퓨틱스, 인크.	새로운 인-함유 갑상선 호르몬 모방약들
US7262318B2 (en) *	2004-03-10	2007-08-28	Pfizer, Inc.	Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) *	2004-06-29	2005-12-29	Pfizer Inc	Substituted heteroaryl- and phenylsulfamoyl compounds
EA200700875A1 (ru) *	2004-11-23	2007-12-28	УОРНЕР-ЛАМБЕРТ КОМПАНИ ЭлЭлСи	Производные 7-(2н-пиразол-3-ил)-3,5-дигидроксигептановой кислоты в качестве ингибиторов hmg co-a редуктазы для лечения липидемии
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
CN101663262B (zh)	2006-12-01	2014-03-26	百时美施贵宝公司	用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA3089569C (en)	2007-06-04	2023-12-05	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
BRPI0911063A2 (pt)	2008-04-11	2016-11-01	Astellas Pharma Inc	composto aminoaçúcar e processo para produção do mesmo
WO2009149279A2 (en)	2008-06-04	2009-12-10	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2010009319A2 (en)	2008-07-16	2010-01-21	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US20120046364A1 (en)	2009-02-10	2012-02-23	Metabasis Therapeutics, Inc.	Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
US20130072519A1 (en)	2010-05-21	2013-03-21	Edward Lee Conn	2-phenyl benzoylamides
WO2012027331A1 (en)	2010-08-27	2012-03-01	Ironwood Pharmaceuticals, Inc.	Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
WO2012120414A2 (en)	2011-03-04	2012-09-13	Pfizer Inc.	Edn3-like peptides and uses thereof
MY188344A (en)	2012-03-09	2021-12-01	Biotropics Malaysia Berhad	Extract formulations of rhodamnia cinerea and uses thereof
WO2014151200A2 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (ja)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	グアニル酸シクラーゼのアゴニストおよびその使用
EP2986599A1 (en)	2013-04-17	2016-02-24	Pfizer Inc.	N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
ES2981866T3 (es)	2013-06-05	2024-10-10	Bausch Health Ireland Ltd	Agonistas ultrapuros de guanilato ciclasa C, método de elaboración y uso de los mismos
RU2746405C2 (ru)	2014-08-29	2021-04-13	Тес Фарма С.Р.Л.	ИНГИБИТОРЫ α-АМИНО-β-КАРБОКСИМУКОНАТ-ε-СЕМИАЛЬДЕГИД-ДЕКАРБОКСИЛАЗЫ
WO2016055901A1 (en)	2014-10-08	2016-04-14	Pfizer Inc.	Substituted amide compounds
KR20190065312A (ko)	2016-10-14	2019-06-11	테스 파마 에스.알.엘.	알파-아미노-베타-카복시뮤콘산 세미알데하이드 데카복실라제의 저해제
WO2020104456A1 (en)	2018-11-20	2020-05-28	Tes Pharma S.R.L	INHIBITORS OF α-AMINO-β-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE
CR20210441A (es)	2019-01-18	2022-03-11	Astrazeneca Ab	Inhibidores de la pcsk9 y métodos de uso de los mismos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2064092C2 (de) *	1970-12-28	1983-06-01	Bayer Ag, 5090 Leverkusen	Inhibitoren für Glykosidhydrolasen aus Actinomyceten
US4062950A (en) *	1973-09-22	1977-12-13	Bayer Aktiengesellschaft	Amino sugar derivatives
DE2347782C3 (de) *	1973-09-22	1979-10-11	Bayer Ag, 5090 Leverkusen	Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4065557A (en) *	1974-03-21	1977-12-27	Bayer Aktiengesellschaft	Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en)	1975-03-19	1979-02-06	American Cyanamid Company	Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) *	1976-04-02	1980-04-03	Bayer Ag, 5090 Leverkusen	Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

1979
- 1979-01-31 CA CA000320579A patent/CA1121290A/en not_active Expired
- 1979-02-07 AU AU44028/79A patent/AU527318B2/en not_active Ceased
- 1979-02-07 ZA ZA79528A patent/ZA79528B/xx unknown
- 1979-02-07 PH PH22174A patent/PH15084A/en unknown
- 1979-02-08 AR AR275445A patent/AR219150A1/es active
- 1979-02-08 IL IL56626A patent/IL56626A0/xx not_active IP Right Cessation
- 1979-02-09 US US06/011,002 patent/US4273765A/en not_active Expired - Lifetime
- 1979-02-12 LU LU80906A patent/LU80906A1/de unknown
- 1979-02-12 NZ NZ189625A patent/NZ189625A/xx unknown
- 1979-02-12 FR FR7903452A patent/FR2416901A1/fr active Granted
- 1979-02-12 HU HU79HO2138A patent/HU181442B/hu not_active IP Right Cessation
- 1979-02-13 JP JP1443879A patent/JPS54163511A/ja active Granted
- 1979-02-13 ES ES477653A patent/ES477653A1/es not_active Expired
- 1979-02-13 NO NO790469A patent/NO153011C/no unknown
- 1979-02-13 SE SE7901276A patent/SE7901276L/ not_active Application Discontinuation
- 1979-02-13 IE IE274/79A patent/IE47916B1/en not_active IP Right Cessation
- 1979-02-13 MC MC791365A patent/MC1253A1/xx unknown
- 1979-02-13 GR GR58344A patent/GR72817B/el unknown
- 1979-02-13 AT AT0108879A patent/AT367451B/de not_active IP Right Cessation
- 1979-02-13 PT PT7969218A patent/PT69218A/pt unknown
- 1979-02-13 DK DK61179A patent/DK149599C/da active
- 1979-02-14 YU YU348/79A patent/YU41437B/xx unknown
- 1979-02-14 FI FI790486A patent/FI63062C/fi not_active IP Right Cessation
- 1979-02-14 DE DE19792905649 patent/DE2905649A1/de not_active Withdrawn
- 1979-02-14 EP EP79100441A patent/EP0003616B1/de not_active Expired
- 1979-02-14 NL NL7901182A patent/NL7901182A/xx not_active Application Discontinuation
- 1979-02-14 DE DE7979100441T patent/DE2962165D1/de not_active Expired

Also Published As

Publication number	Publication date
PT69218A (en)	1979-03-01
ZA79528B (en)	1980-02-27
NL7901182A (nl)	1979-08-16
HU181442B (en)	1983-07-28
NO790469L (no)	1979-08-15
FR2416901A1 (fr)	1979-09-07
DK61179A (da)	1979-08-15
CA1121290A (en)	1982-04-06
YU34879A (en)	1983-01-21
JPS643877B2 (es)	1989-01-23
ES477653A1 (es)	1980-03-01
PH15084A (en)	1982-07-02
AU4402879A (en)	1979-08-23
DE2962165D1 (en)	1982-03-25
EP0003616A2 (de)	1979-08-22
US4273765A (en)	1981-06-16
IE790274L (en)	1979-08-14
FI790486A (fi)	1979-08-15
DK149599B (da)	1986-08-04
ATA108879A (de)	1981-11-15
EP0003616B1 (de)	1982-02-24
AT367451B (de)	1982-07-12
DE2905649A1 (de)	1979-08-16
MC1253A1 (fr)	1980-01-14
AR219150A1 (es)	1980-07-31
EP0003616A3 (en)	1979-09-05
IE47916B1 (en)	1984-07-25
LU80906A1 (de)	1980-09-24
YU41437B (en)	1987-06-30
IL56626A0 (en)	1979-05-31
GR72817B (es)	1983-12-06
AU527318B2 (en)	1983-02-24
FR2416901B1 (es)	1980-10-24
SE7901276L (sv)	1979-08-15
FI63062C (fi)	1983-04-11
NO153011C (no)	1986-01-02
JPS54163511A (en)	1979-12-26
NO153011B (no)	1985-09-23
FI63062B (fi)	1982-12-31
NZ189625A (en)	1981-05-01

Publication	Publication Date	Title
DK149599C (da)	1987-06-01	Fremgangsmaade til fremstilling af aminosukkerderivater kaldet trestatina, trestatin b og trestatin c eller salte deraf
DK149895C (da)	1987-04-21	Fremgangsmaade til fremstilling af alfa-aminoacylprolyl-ng-carboxy-argininaldehydderivater eller farmaceutisk acceptable syreadditionssalte deraf
DK513480A (da)	1981-07-09	N-adamantansubstituerede tetrapeptidamider eller farmakologisk acceptable salte deraf og fremgangsmaade til deres fremstilling
DK15279A (da)	1979-07-17	Fremgangsmaade til fremstilling af tetrahydropyridinylindolderivater eller additionssalte deraf
DK352176A (da)	1977-02-21	Fremgangsmade til femstilling af acyl-3-oxo-1,2-benzisothiazoliner eller acylsacchariner
DK503080A (da)	1981-05-28	Fremgangsmaade til fremstilling af imdazolderivater eller salte deraf
DK5976A (da)	1976-07-10	Fremgangsmade til fremstilling af biphenyloxyderivater eller salte heraf
DK473182A (da)	1983-04-28	Fremgangsmaade til fremstilling af 3-aminopregn-5-enderivater eller salte deraf
DK76578A (da)	1978-08-23	Fremgangsmaade til fremstilling af d,1-5-methyltetrahydrofolinsyre eller salte deraf
DK11480A (da)	1980-08-04	Fremgangsmaade til fremstilling af anthracyclinderivater og syreadditionssalte deraf
DK27078A (da)	1978-07-21	Fremgangsmaade til fremstilling af imidazoquinoliner eller salte deraf
DK154650C (da)	1989-05-01	Analogifremgangsmaade til fremstilling af sukkerderivater
DK75878A (da)	1978-08-23	Fremgangsmaade til fremstilling af 20,21,-di-noreburnameninderivater eller additionssalte deraf
DK324979A (da)	1980-02-03	Fremgangsmaade til fremstilling af imidazoquinoxaliner eller salte deraf
DK511878A (da)	1979-05-19	Fremgangsmaade til fremstilling af imidazobenzoazepiner eller salte deraf
DK232777A (da)	1977-12-16	Fremgangsmade til fremstilling af imidazothiaziner eller farmaceutisk acceptable salte deraf
DK508776A (da)	1977-05-13	Fremgangsmade til fremstilling af derivater af daunorubicin eller syreadditionssalte deraf
DK58677A (da)	1977-08-14	Fremgangsmade til fremstilling af m-trifluormethylphenylpiperidinderivater eller additionssalte deraf
DK338376A (da)	1977-01-29	Fremgangsmade til fremstilling af aminobenzocycloheptenderivater eller additionssalte deraf
DK127676A (da)	1976-10-08	Fremgangsmade til fremstilling af 9-alkylamino-erythromyciner eller salte deraf
DK255276A (da)	1976-12-11	Fremgangsmade til fremstilling af substituerede benzamider eller salte, oxider og optisk aktive isomere deraf
DK232877A (da)	1977-12-16	Fremgangsmade til fremstilling af 2-imino-3-aminothiazolidiner eller farmaceutisk acceptable salte deraf
DK146540C (da)	1984-05-21	Fremgangsmaade til fremstilling af alkaloider af leurosin-typen, eller syreadditionssalte deraf
DK57778A (da)	1978-08-11	Fremgangsmaade til fremstilling af 1,3-disubstitueret urinstof eller 2-thioruinstof
DK224381A (da)	1981-11-23	Fremgangsmaade til fremstilling af benzazolderivater eller salte deraf