DK1480983T3 - Heteroarylsubstituerede 2-pyridinyl- og 2-pyrimidinyl- 6,7,8,9-tetrahydropyrimido[1,2a]pyrimidin-4-onderivater - Google Patents

Heteroarylsubstituerede 2-pyridinyl- og 2-pyrimidinyl- 6,7,8,9-tetrahydropyrimido[1,2a]pyrimidin-4-onderivater

Info

Publication number: DK1480983T3
Authority: DK; Denmark
Prior art keywords: undivatives; tetrahydropyrimido; pyridinyl; pyrimidinyl; pyrimidine
Prior art date: 2002-02-28

Application number

DK03717210T

Other languages

English (en)

Inventor

Alistair Lochead

Philippe Yaiche

Alain Nedelec

Mourad Saady

Original Assignee

Sanofi Aventis

Mitsubishi Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-28

Filing date

2003-02-26

Publication date

2006-03-27

2002-02-28 Priority claimed from EP02290486A external-priority patent/EP1348708A1/en

2002-02-28 Priority claimed from EP02290485A external-priority patent/EP1340758A1/en

2003-02-26 Application filed by Sanofi Aventis, Mitsubishi Pharma Corp filed Critical Sanofi Aventis

2006-03-27 Application granted granted Critical

2006-03-27 Publication of DK1480983T3 publication Critical patent/DK1480983T3/da

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Addiction (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Physical Education & Sports Medicine (AREA)
Agronomy & Crop Science (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Pest Control & Pesticides (AREA)
Plant Pathology (AREA)
Dentistry (AREA)

DK03717210T 2002-02-28 2003-02-26 Heteroarylsubstituerede 2-pyridinyl- og 2-pyrimidinyl- 6,7,8,9-tetrahydropyrimido[1,2a]pyrimidin-4-onderivater DK1480983T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02290486A EP1348708A1 (en)	2002-02-28	2002-02-28	Heteroaryl substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)one derivatives
EP02290485A EP1340758A1 (en)	2002-02-28	2002-02-28	Heteroaryl substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)one derivatives

Publications (1)

Publication Number	Publication Date
DK1480983T3 true DK1480983T3 (da)	2006-03-27

Family

ID=27767034

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03717210T DK1480983T3 (da)	2002-02-28	2003-02-26	Heteroarylsubstituerede 2-pyridinyl- og 2-pyrimidinyl- 6,7,8,9-tetrahydropyrimido[1,2a]pyrimidin-4-onderivater

Country Status (22)

Country	Link
US (2)	US7232827B2 (da)
EP (1)	EP1480983B1 (da)
JP (1)	JP4458851B2 (da)
KR (1)	KR101030629B1 (da)
CN (1)	CN1315832C (da)
AR (1)	AR038619A1 (da)
AT (1)	ATE309247T1 (da)
AU (1)	AU2003221500B9 (da)
BR (1)	BR0308109A (da)
CA (1)	CA2474823C (da)
DE (1)	DE60302221T2 (da)
DK (1)	DK1480983T3 (da)
EA (1)	EA007737B1 (da)
ES (1)	ES2250883T3 (da)
IL (1)	IL163287A (da)
MX (1)	MXPA04008364A (da)
NO (1)	NO329805B1 (da)
NZ (1)	NZ534466A (da)
PL (1)	PL372465A1 (da)
SI (1)	SI1480983T1 (da)
TW (1)	TWI303637B (da)
WO (1)	WO2003072579A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0408186A (pt)	2003-03-07	2006-04-04	Sanofi Aventis	derivados de 2-(diaza-biciclo-alquil)-pirimidona substituìdos
EP1454910A1 (en)	2003-03-07	2004-09-08	Sanofi-Synthelabo	Substituted pyrimidinyl-2-(diaza-bicyclo-alkyl)-pyrimidone derivatives
EP1557417B1 (en) *	2003-12-19	2007-03-07	Sanofi-Aventis	Substituted 8'-pyri(mi)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-a] pyrimidin-6-one derivatives
US20080050314A1 (en) *	2004-02-26	2008-02-28	Bayer Healthcare Ag	Diagnostics and Therapeutics for Diseases Associated With Glycogen Synthase Kinase 3 Beta (Gsk3b)
DE102004010207A1 (de)	2004-03-02	2005-09-15	Aventis Pharma S.A.	Neue 4-Benzimidazol-2-yl-pyridazin-3-on-Derivate
DE102004010194A1 (de) *	2004-03-02	2005-10-13	Aventis Pharma Deutschland Gmbh	4-Benzimidazol-2-yl-pyridazin-3-on-Derivate, ihre Herstellung und Verwendung in Arzneimitteln
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
EP2275096A3 (en)	2005-08-26	2011-07-13	Braincells, Inc.	Neurogenesis via modulation of the muscarinic receptors
EP1940389A2 (en)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
JP2009513672A (ja)	2005-10-31	2009-04-02	ブレインセルス，インコーポレイティド	神経発生のｇａｂａ受容体媒介調節
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
EP2382975A3 (en)	2006-05-09	2012-02-29	Braincells, Inc.	Neurogenesis by modulating angiotensin
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
JP5663571B2 (ja) *	2009-07-02	2015-02-04	サノフイ	新規２，３−ジヒドロ−１Ｈ−イミダゾ｛１，２−ａ｝ピリミジン−５−オン誘導体、これらの調製およびこれらの薬学的使用
FR2947551B1 (fr) *	2009-07-02	2012-05-18	Sanofi Aventis	Nouveaux derives de 1,2,3,4-tetrahydro-pyrimido{1,2-a)pyrimidin-6-one, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de phosphorylation d'akt (pkb)
MY155661A (en) *	2009-07-02	2015-11-13	Sanofi Sa	Novel 1,2,3,4-tetrahydropyrimido{1,2-a}pyrimidin-6-one derivatives, preparation thereof and pharmaceutical use thereof
FR2947550B1 (fr) *	2009-07-02	2012-05-18	Sanofi Aventis	Nouveaux derives de 2,3-dihydro-1h-imidazo{1,2-a}pyrimidin-5-one, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de phosphorylation d'akt (pkb)
CN102715186A (zh) *	2012-06-15	2012-10-10	王学权	一种增效除草组合物
FR2992314B1 (fr)	2012-06-22	2015-10-16	Sanofi Sa	Nouveaux derives de 2,3-dihydro-1h-imidazo{1,2-a}pyrimidin-5-one et 1,2,3,4-tetrahydro-pyrimido{1,2-a}pyrimidin-6-one comportant une morpholine substituee, leur preparation et leur utilisation pharmaceutique
EA031419B1 (ru) *	2014-04-01	2018-12-28	Пфайзер Инк.	ХРОМЕН И 1,1a,2,7b-ТЕТРАГИДРОЦИКЛОПРОПА[c]ХРОМЕН ПИРИДОПИРАЗИНДИОНЫ В КАЧЕСТВЕ МОДУЛЯТОРА ГАММА-СЕКРЕТАЗЫ
WO2015155738A2 (en)	2014-04-09	2015-10-15	Christopher Rudd	Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
WO2018214866A1 (zh) *	2017-05-24	2018-11-29	上海和誉生物医药科技有限公司	一种氮杂芳基衍生物、其制备方法和在药学上的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998024782A2 (en) *	1996-12-05	1998-06-11	Amgen Inc.	Substituted pyrimidine compounds and their use
TWI241298B (en) *	1998-09-25	2005-10-11	Mitsubishi Chem Corp	Pyrimidone derivatives
AR030587A1 (es)	2000-09-01	2003-08-27	Sanofi Aventis	Derivados de 2-piridinil-6,7,8,9-tetrahidropirimido[1,2-a]pirimidin-4-ona y 7-piridinil-2,3-dihidroimidazo[1,2-a]pirimidin-5(1h)-ona

2003
- 2003-02-26 BR BR0308109-5A patent/BR0308109A/pt active Search and Examination
- 2003-02-26 PL PL03372465A patent/PL372465A1/xx not_active IP Right Cessation
- 2003-02-26 MX MXPA04008364A patent/MXPA04008364A/es active IP Right Grant
- 2003-02-26 NZ NZ534466A patent/NZ534466A/en not_active IP Right Cessation
- 2003-02-26 JP JP2003571285A patent/JP4458851B2/ja not_active Expired - Fee Related
- 2003-02-26 EP EP03717210A patent/EP1480983B1/en not_active Expired - Lifetime
- 2003-02-26 AU AU2003221500A patent/AU2003221500B9/en not_active Ceased
- 2003-02-26 US US10/504,677 patent/US7232827B2/en not_active Expired - Fee Related
- 2003-02-26 DK DK03717210T patent/DK1480983T3/da active
- 2003-02-26 KR KR1020047013466A patent/KR101030629B1/ko not_active Expired - Fee Related
- 2003-02-26 CA CA2474823A patent/CA2474823C/en not_active Expired - Fee Related
- 2003-02-26 DE DE60302221T patent/DE60302221T2/de not_active Expired - Lifetime
- 2003-02-26 EA EA200400936A patent/EA007737B1/ru not_active IP Right Cessation
- 2003-02-26 CN CNB038092549A patent/CN1315832C/zh not_active Expired - Fee Related
- 2003-02-26 SI SI200330138T patent/SI1480983T1/sl unknown
- 2003-02-26 WO PCT/EP2003/002651 patent/WO2003072579A1/en not_active Ceased
- 2003-02-26 AT AT03717210T patent/ATE309247T1/de active
- 2003-02-26 ES ES03717210T patent/ES2250883T3/es not_active Expired - Lifetime
- 2003-02-27 TW TW092104217A patent/TWI303637B/zh not_active IP Right Cessation
- 2003-02-28 AR ARP030100657A patent/AR038619A1/es unknown
2004
- 2004-07-29 IL IL163287A patent/IL163287A/en not_active IP Right Cessation
- 2004-08-26 NO NO20043565A patent/NO329805B1/no not_active IP Right Cessation
2007
- 2007-05-16 US US11/749,349 patent/US7465737B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2005519086A (ja)	2005-06-30
MXPA04008364A (es)	2005-07-26
US7232827B2 (en)	2007-06-19
IL163287A (en)	2009-12-24
US20070225300A1 (en)	2007-09-27
NZ534466A (en)	2006-04-28
CA2474823C (en)	2011-02-22
CN1315832C (zh)	2007-05-16
NO329805B1 (no)	2010-12-20
TW200402421A (en)	2004-02-16
EP1480983A1 (en)	2004-12-01
US7465737B2 (en)	2008-12-16
CN1649871A (zh)	2005-08-03
ATE309247T1 (de)	2005-11-15
AU2003221500A1 (en)	2003-09-09
KR101030629B1 (ko)	2011-04-20
KR20040087333A (ko)	2004-10-13
AU2003221500B2 (en)	2008-02-14
ES2250883T3 (es)	2006-04-16
AR038619A1 (es)	2005-01-19
PL372465A1 (en)	2005-07-25
TWI303637B (en)	2008-12-01
EA200400936A1 (ru)	2005-02-24
JP4458851B2 (ja)	2010-04-28
SI1480983T1 (sl)	2006-04-30
WO2003072579A1 (en)	2003-09-04
NO20043565L (no)	2004-11-25
CA2474823A1 (en)	2003-09-04
DE60302221D1 (de)	2005-12-15
EP1480983B1 (en)	2005-11-09
AU2003221500B9 (en)	2008-11-20
AU2003221500C1 (en)	2008-10-02
DE60302221T2 (de)	2006-08-03
EA007737B1 (ru)	2006-12-29
US20050222172A1 (en)	2005-10-06
BR0308109A (pt)	2005-01-04

Publication	Publication Date	Title
DK1480983T3 (da)	2006-03-27	Heteroarylsubstituerede 2-pyridinyl- og 2-pyrimidinyl- 6,7,8,9-tetrahydropyrimido[1,2a]pyrimidin-4-onderivater
HUS1500055I1 (hu)	2016-03-29	HIV-gátló pirimidinszármazékok
ATE472536T1 (de)	2010-07-15	Pyridin- und pyrimidin-derivate
ATE372988T1 (de)	2007-09-15	Pyrimidin-derivate
ATE370120T1 (de)	2007-09-15	Substituierte 2-pyridin-cyclohexan-1,4- diaminderivate
CY2014041I2 (el)	2016-07-27	2,3-διυδρο-6-νιτροϊμιδαζο 2,1 -b-οξαζολια
DK1416935T3 (da)	2008-07-07	4-Amino-6-phenyl-pyrrolo[2,3-d]pyrimidinderivater
DK1487805T3 (da)	2012-10-15	Pyrimidinderivater
DE50213336D1 (de)	2009-04-16	Substituierte 2-thio-3,5-dicyano-4-phenyl-6-aminopyridine und ihre verwendung
DE50207849D1 (de)	2006-09-28	Substituierte 2-oxy-3,5-dicyano-4-aryl-6-aminopyridine und ihre verwendung
DK1412328T3 (da)	2007-02-12	Dolastatin-10-derivater
FR2806720B1 (fr)	2006-12-08	Derives de 2,2,6,6-diethyl-dimethyl-1-alcoxypiperidines et 1-oxydes correspondants
ATE303388T1 (de)	2005-09-15	Substituierte 2-pyridinyl-6,7,8,9- tetrahydropyrimidoc1,2-aöpyrimidin-4-on- und 7- pyridinyl-2,3-dihydroimidazo-c1,2-aöpyrimidin- 5(1h)onderivate
NO20042742L (no)	2004-08-24	Pyrimidinforbindelser
HUP0401684A3 (en)	2005-06-28	Nicotinic acid-heterocyclyl-amides and analogous pyrimidine derivatives serving as pesticides
PT1334106E (pt)	2006-08-31	Derivados de imidazole, seu metodo de producao e sua utilizacao
NO20032291D0 (no)	2003-05-21	Pyrimidinderivater
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