DK144068C - METHOD OF ANALOGUE FOR THE PREPARATION OF 2-BROMO-6BETA, 9ALFA-DIFLUOR-11BETA, 17ALFA, 21-TRIHYDROXYPREGNA-1,4-DIEN-3,20-DION-21 MONOESTERS OR -17ALFA, 21-DIESTERS - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF 2-BROMO-6BETA, 9ALFA-DIFLUOR-11BETA, 17ALFA, 21-TRIHYDROXYPREGNA-1,4-DIEN-3,20-DION-21 MONOESTERS OR -17ALFA, 21-DIESTERS

Info

Publication number: DK144068C
Authority: DK; Denmark
Prior art keywords: 17alfa; 9alfa; trihydroxypregna; 6beta; 11beta
Prior art date: 1974-02-27

Application number

DK61575A

Other languages

Danish (da)

Other versions

DK144068B (en

DK61575A (en

Inventor

M Riva

L Toscano

Original Assignee

Pierrel Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-02-27

Filing date

1975-02-19

Publication date

1982-05-03

1975-02-19 Application filed by Pierrel Spa filed Critical Pierrel Spa

1975-10-27 Publication of DK61575A publication Critical patent/DK61575A/da

1980-06-27 Priority to DK280280A priority Critical patent/DK280280A/en

1981-11-30 Publication of DK144068B publication Critical patent/DK144068B/en

1982-05-03 Application granted granted Critical

1982-05-03 Publication of DK144068C publication Critical patent/DK144068C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Rheumatology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK61575A 1974-02-27 1975-02-19 METHOD OF ANALOGUE FOR THE PREPARATION OF 2-BROMO-6BETA, 9ALFA-DIFLUOR-11BETA, 17ALFA, 21-TRIHYDROXYPREGNA-1,4-DIEN-3,20-DION-21 MONOESTERS OR -17ALFA, 21-DIESTERS DK144068C (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK280280A DK280280A (en)	1974-02-27	1980-06-27	METHOD OF ANALOGY FOR PREPARATION OF 2-BROMO-6BETA, 9ALFA-DIFLUOR-11BETA, 17ALFA, 21-TRIHYDROXYPREGNA-1,4-DIEN-3,20-DION-17 MONOESTERS

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
GB8928/74A GB1499822A (en)	1974-02-27	1974-02-27	2-bromo-6beta-fluoropregna-1,4-diene-3,20-diones
GB892874		1974-02-27
GB2998474		1974-07-05
GB2998474		1974-07-05
GB3294574		1974-07-25
GB3294574		1974-07-25
GB4998274		1974-11-19
GB4998274		1974-11-19

Publications (3)

Publication Number	Publication Date
DK61575A DK61575A (en)	1975-10-27
DK144068B DK144068B (en)	1981-11-30
DK144068C true DK144068C (en)	1982-05-03

Family

ID=27447687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK61575A DK144068C (en)	1974-02-27	1975-02-19	METHOD OF ANALOGUE FOR THE PREPARATION OF 2-BROMO-6BETA, 9ALFA-DIFLUOR-11BETA, 17ALFA, 21-TRIHYDROXYPREGNA-1,4-DIEN-3,20-DION-21 MONOESTERS OR -17ALFA, 21-DIESTERS

Country Status (18)

Country	Link
JP (1)	JPS5614677B2 (en)
AR (1)	AR218601A1 (en)
BE (1)	BE826030A (en)
CA (1)	CA1064476A (en)
CH (1)	CH608243A5 (en)
DE (3)	DE2508136C3 (en)
DK (1)	DK144068C (en)
ES (3)	ES435067A1 (en)
FI (1)	FI56188C (en)
FR (1)	FR2261776B1 (en)
GB (1)	GB1499822A (en)
IE (1)	IE42112B1 (en)
LU (1)	LU71908A1 (en)
NO (1)	NO144527C (en)
NZ (1)	NZ176716A (en)
RO (1)	RO78881A (en)
SE (1)	SE410736B (en)
YU (3)	YU108281A (en)

1974
- 1974-02-27 GB GB8928/74A patent/GB1499822A/en not_active Expired
1975
- 1975-02-10 CA CA219,681A patent/CA1064476A/en not_active Expired
- 1975-02-14 FR FR7504616A patent/FR2261776B1/fr not_active Expired
- 1975-02-19 DK DK61575A patent/DK144068C/en not_active IP Right Cessation
- 1975-02-20 NZ NZ176716A patent/NZ176716A/en unknown
- 1975-02-24 IE IE379/75A patent/IE42112B1/en unknown
- 1975-02-24 AR AR257732A patent/AR218601A1/en active
- 1975-02-25 ES ES435067A patent/ES435067A1/en not_active Expired
- 1975-02-25 NO NO750633A patent/NO144527C/en unknown
- 1975-02-25 CH CH232575A patent/CH608243A5/en not_active IP Right Cessation
- 1975-02-25 FI FI750537A patent/FI56188C/en not_active IP Right Cessation
- 1975-02-25 LU LU71908A patent/LU71908A1/xx unknown
- 1975-02-25 DE DE2508136A patent/DE2508136C3/en not_active Expired
- 1975-02-26 BE BE153787A patent/BE826030A/en not_active IP Right Cessation
- 1975-02-26 JP JP2298075A patent/JPS5614677B2/ja not_active Expired
- 1975-02-26 SE SE7502146A patent/SE410736B/en unknown
- 1975-02-26 RO RO7581496A patent/RO78881A/en unknown
- 1975-07-25 DE DE2533323A patent/DE2533323C3/en not_active Expired
- 1975-07-25 DE DE2533377A patent/DE2533377C3/en not_active Expired
1977
- 1977-02-15 ES ES455934A patent/ES455934A1/en not_active Expired
- 1977-02-15 ES ES455933A patent/ES455933A1/en not_active Expired
1981
- 1981-04-27 YU YU01082/81A patent/YU108281A/en unknown
- 1981-04-27 YU YU01084/81A patent/YU108481A/en unknown
- 1981-04-27 YU YU01083/81A patent/YU108381A/en unknown

Also Published As

Publication number	Publication date
NO750633L (en)	1975-08-28
YU108481A (en)	1982-02-28
DK144068B (en)	1981-11-30
DE2533323B2 (en)	1978-11-16
JPS5614677B2 (en)	1981-04-06
SE410736B (en)	1979-10-29
ES435067A1 (en)	1977-07-01
DE2533323A1 (en)	1976-02-12
NO144527C (en)	1981-09-23
IE42112B1 (en)	1980-06-04
CA1064476A (en)	1979-10-16
SE7502146L (en)	1975-08-28
JPS50126652A (en)	1975-10-04
DE2508136C3 (en)	1979-06-21
YU108281A (en)	1982-02-28
YU108381A (en)	1982-02-28
RO78881A (en)	1982-07-06
FI750537A (en)	1975-08-28
GB1499822A (en)	1978-02-01
FI56188B (en)	1979-08-31
ES455934A1 (en)	1978-05-01
DE2533377C3 (en)	1979-08-02
NO144527B (en)	1981-06-09
AR218601A1 (en)	1980-06-30
CH608243A5 (en)	1978-12-29
NZ176716A (en)	1978-07-10
LU71908A1 (en)	1975-06-24
DE2533377B2 (en)	1978-11-16
DE2533377A1 (en)	1976-02-05
DE2508136B2 (en)	1978-11-02
DE2533323C3 (en)	1979-07-12
FR2261776A1 (en)	1975-09-19
IE42112L (en)	1975-08-27
DK61575A (en)	1975-10-27
ES455933A1 (en)	1978-05-01
DE2508136A1 (en)	1975-10-30
FI56188C (en)	1979-12-10
FR2261776B1 (en)	1978-07-21
BE826030A (en)	1975-06-16

Publication	Publication Date	Title
DK349875A (en)	1976-02-03	PROCEDURE FOR PREPARING CONCRETE CONSTRUCTIONS
DK138800B (en)	1978-10-30	Analogous process for the preparation of 4-aminoquinazoline derivatives.
DK138992B (en)	1978-11-27	ANALOGICAL PROCEDURE FOR THE PREPARATION OF 5,9BETA-DISUBSTITUTED 2-TETRAHYDROFURFURYL-6,7-BENZOMORPHANES OR ACID ADDITONES THEREOF
DK138501C (en)	1979-02-19	ANALOGICAL PROCEDURE FOR THE PREPARATION OF 3ALFA-HYDROXY-D-HOMO-5ALFA-PREGNAN-11,20-DIONER
DK150302C (en)	1987-09-28	METHOD OF ANALOGUE FOR THE PREPARATION OF SPIRO-HYDANTOIN COMPOUNDS OR PHARMACOLOGICAL ACCEPTABLE BASES
DK144298C (en)	1982-07-12	PROCEDURE FOR THE PREPARATION OF ALKYL-TERT BUTYLETHERS
FI56724B (en)	1979-11-30	AXIALFLAEKT MED FLERA SKILT JUSTERBARA BLAD
DK201675A (en)	1975-11-23	PROCEDURE FOR THE PREPARATION OF (1HYDROXIMINO-2,2-DISUBSTITUTED-5-INDANYLOXY (OR THIO)) ALKANIC ACIDS
DK157138C (en)	1990-04-16	METHOD FOR PREPARING 7BETA-ACYLAMINO-7ALFA-ALCOXYCEPHALOSPORINES OR 6BETA-ACYLAMINO-6ALFA-ALCOXYPENICILLINES
DK490775A (en)	1976-05-07	PROCEDURE FOR THE PREPARATION OF POSSIBLY SUBSTITUTED 1,2,3,5-TETRAHYDROIMIDAZO (2,1-B) -QUINAZOLIN-2-ONERS
DK146542C (en)	1984-04-09	METHOD OF ANALOGUE FOR THE PREPARATION OF DAUNOSAMINYLANTHRACYCLIONS
DK137835B (en)	1978-05-16	Analogous process for the preparation of thienothiazine derivatives.
DK179675A (en)	1975-10-27	PROCEDURE FOR THE PREPARATION OF 6-AMINO-5-R3-2,4-DIAMINOPYRIMIDINE-3-OXIDES
DK139846B (en)	1979-04-30	Analogous process for the preparation of 3-alkoxypyrazine-2-carboxamides.
DK136534C (en)	1978-03-28	ANALOGICAL PROCEDURE FOR THE PREPARATION OF D-HOMOPREGNA-1,4-DIENE-3,20-DIONER
DK147854C (en)	1985-07-22	METHOD OF ANALOGUE FOR THE PREPARATION OF N- (1-BENZYLPIPERID-4-YL) -BENZAMIDES
DK136729C (en)	1978-05-01	ANALOGICAL PROCEDURE FOR THE PREPARATION OF 1ALFA, 17BETA-DIHYDROXY-17BETA-ALKYNYL-4-OESTREN-3-ONERS
DK144033C (en)	1982-04-26	METHOD OF ANALOGUE FOR THE PREPARATION OF L-3- (3,4-DIHYDROXY-PHENYL) -2-METHYL-ALANINE PEPTIDES OR PHARMACOLOGICAL ACCEPTABLE SALTS THEREOF
DK153759C (en)	1989-01-09	METHOD OF ANALOGUE FOR THE PREPARATION OF PROSTANIC ACID DERIVATIVES
DK146718C (en)	1984-05-21	METHOD OF ANALOGUE FOR THE PREPARATION OF BENZOBICYCLONONES
DK143556C (en)	1982-02-15	METHOD OF ANALOGUE FOR THE PREPARATION OF SUBSTITUTED PHENYLISOTHYOUR INGREDIENTS
DK499075A (en)	1976-05-08	PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINS
DK156271C (en)	1989-12-11	METHOD OF ANALOGUE FOR THE PREPARATION OF 1,2-5,6-DIANHYDRO-3,4-DI-O-ACYLGALACTITOLD DERIVATIVES
DK144068C (en)	1982-05-03	METHOD OF ANALOGUE FOR THE PREPARATION OF 2-BROMO-6BETA, 9ALFA-DIFLUOR-11BETA, 17ALFA, 21-TRIHYDROXYPREGNA-1,4-DIEN-3,20-DION-21 MONOESTERS OR -17ALFA, 21-DIESTERS
DK143332C (en)	1981-12-07	PROCEDURE FOR THE PREPARATION OF ORTHO-HYDROXYALCYCLED PHENOLES

Legal Events

Date	Code	Title	Description
1984-10-06	PBP	Patent lapsed