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DK1273304T4 - Anvendelse af interleukin-15 - Google Patents

Anvendelse af interleukin-15

Info

Publication number
DK1273304T4
DK1273304T4 DK02014656T DK02014656T DK1273304T4 DK 1273304 T4 DK1273304 T4 DK 1273304T4 DK 02014656 T DK02014656 T DK 02014656T DK 02014656 T DK02014656 T DK 02014656T DK 1273304 T4 DK1273304 T4 DK 1273304T4
Authority
DK
Denmark
Prior art keywords
antibodies
alpha
inhibiting
compounds
receptor
Prior art date
Application number
DK02014656T
Other languages
Danish (da)
English (en)
Other versions
DK1273304T3 (da
Inventor
Johan Adriaan Marc Grooten
Hans Peter Raf Dooms
Walter Charles Fiers
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8228040&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1273304(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DK1273304T3 publication Critical patent/DK1273304T3/da
Publication of DK1273304T4 publication Critical patent/DK1273304T4/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2086IL-13 to IL-16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/14Lymphokine; related peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/14Lymphokine; related peptides
    • Y10S930/141Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK02014656T 1997-02-21 1998-02-23 Anvendelse af interleukin-15 DK1273304T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97200515 1997-02-21

Publications (2)

Publication Number Publication Date
DK1273304T3 DK1273304T3 (da) 2005-09-12
DK1273304T4 true DK1273304T4 (da) 2009-08-31

Family

ID=8228040

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02014656T DK1273304T4 (da) 1997-02-21 1998-02-23 Anvendelse af interleukin-15

Country Status (9)

Country Link
US (3) US6344192B1 (es)
EP (2) EP0971728B1 (es)
AT (2) ATE295736T1 (es)
AU (1) AU6726698A (es)
DE (2) DE69810091T2 (es)
DK (1) DK1273304T4 (es)
ES (1) ES2187946T3 (es)
WO (1) WO1998036768A1 (es)
ZA (1) ZA981478B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192935B1 (en) 1993-03-08 2007-03-20 Amgen Inc. Polynucleotides encoding epithelium-derived T-cell factor and uses thereof
IL126919A0 (en) * 1998-11-05 1999-09-22 Univ Ben Gurion Antisense oligomer
US5985663A (en) * 1998-11-25 1999-11-16 Isis Pharmaceuticals Inc. Antisense inhibition of interleukin-15 expression
EP1927657A3 (en) * 2000-05-11 2008-10-22 Baylor Research Institute Compositions and methods for producing antigen-presenting cells
MXPA03002278A (es) * 2000-09-14 2004-12-03 Beth Israel Hospital Modulacion de respuestas de la celula t mediadas por il-2 e il-15.
US7041302B2 (en) * 2001-01-09 2006-05-09 Biother Corporation Therapeutic modulation of the tumor inflammatory response
US7329405B2 (en) 2001-08-23 2008-02-12 Genmab A/S Human antibodies specific for interleukin 15 (IL-15)
US7247304B2 (en) 2001-08-23 2007-07-24 Genmab A/S Methods of treating using anti-IL-15 antibodies
RS51829B (sr) 2001-08-23 2012-02-29 Genmab A/S. Ljudska antitela specifična za interleukin 15 (il-15)
CU23093A1 (es) * 2002-10-09 2005-10-19 Ct Ingenieria Genetica Biotech Composición vacunal que comprende interleucina-15 (il-15)
PL1606318T3 (pl) 2003-03-26 2010-01-29 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Ulepszone białka fuzyjne FC
DE602004031681D1 (de) 2003-07-21 2011-04-14 Transgene Sa Multifunktionelle Cytokine
CU23472A1 (es) * 2004-09-17 2009-12-17 Ct Ingenieria Genetica Biotech Péptido antagonista de la interleucina-15
DK1809321T3 (da) 2004-10-08 2012-06-25 Us Gov Health & Human Serv Adoptiv immunterapi med forøget T-lymfocytoverlevelse
EP1899364B2 (en) 2005-05-17 2024-10-30 University of Connecticut Compositions and methods for immunomodulation in an organism
EP1777294A1 (en) 2005-10-20 2007-04-25 Institut National De La Sante Et De La Recherche Medicale (Inserm) IL-15Ralpha sushi domain as a selective and potent enhancer of IL-15 action through IL-15Rbeta/gamma, and hyperagonist (IL15Ralpha sushi -IL15) fusion proteins
US20070160578A1 (en) * 2005-12-14 2007-07-12 The Gov. Of The Usa As Represented By The Secretary Of The Dep. Of Health And Human Services Expansion of natural killer and CD8 T-cells with IL-15R/ligand activator complexes
EP1984505B1 (en) 2006-01-13 2019-12-25 The Government of the U.S.A., as repr. by the Secretary, Dept. of Health & Human Services, the Nat. Inst. of Health Codon optimized il-15 and il-15r-alpha genes for expression in mammalian cells
US20080131415A1 (en) * 2006-11-30 2008-06-05 Riddell Stanley R Adoptive transfer of cd8 + t cell clones derived from central memory cells
ES2518393T3 (es) 2007-05-11 2014-11-05 Altor Bioscience Corporation Moléculas de fusión y variantes de IL-15
WO2009002562A2 (en) 2007-06-27 2008-12-31 Marine Polymer Technologies, Inc. Complexes of il-15 and il-15ralpha and uses thereof
NZ714757A (en) 2009-08-14 2018-07-27 Us Gov Health & Human Services Use of il-15 to increase thymic output and to treat lymphopenia
KR20140020228A (ko) 2010-09-21 2014-02-18 알토 바이오사이언스 코포레이션 다량체성 아이엘 15 용해성 융합 분자 및 그의 제조 및 사용 방법
US11053299B2 (en) 2010-09-21 2021-07-06 Immunity Bio, Inc. Superkine
CN110200997A (zh) 2011-03-23 2019-09-06 弗雷德哈钦森癌症研究中心 用于细胞免疫治疗的方法和组合物
CA2909576C (en) 2013-04-19 2023-07-18 Cytune Pharma Cytokine derived treatment with reduced vascular leak syndrome
CN106659775B (zh) 2014-06-30 2021-08-06 阿尔托生物科学有限公司 基于il-15的分子及其方法和用途
JP7492336B2 (ja) 2016-10-21 2024-05-29 アルター・バイオサイエンス・コーポレーション 多量体il-15に基づく分子
WO2023086772A1 (en) 2021-11-12 2023-05-19 Xencor, Inc. Bispecific antibodies that bind to b7h3 and nkg2d
WO2024102636A1 (en) 2022-11-07 2024-05-16 Xencor, Inc. Bispecific antibodies that bind to b7h3 and mica/b
US20250243279A1 (en) 2023-10-17 2025-07-31 Xencor, Inc. Bispecific antibodies that bind to nkp46 and mica/b

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747024A (en) * 1993-03-08 1998-05-05 Immunex Corporation Vaccine adjuvant comprising interleukin-15
US5574138A (en) * 1993-03-08 1996-11-12 Immunex Corporation Epithelium-derived T-cell factor
US5591630A (en) * 1994-05-06 1997-01-07 Immunex Corporation Monoclonal antibodies that bind interleukin-15 receptors
DK0789588T3 (da) * 1994-11-17 2005-05-30 Univ South Florida Metode til fremstilling af et medikament til behandling af sekundær immundefekt
US5795966A (en) * 1995-02-22 1998-08-18 Immunex Corp Antagonists of interleukin-15
WO1997014433A1 (en) * 1995-10-17 1997-04-24 Wayne State University Chicken interleukin-15 and uses thereof
US5870759A (en) * 1996-10-09 1999-02-09 Oracle Corporation System for synchronizing data between computers using a before-image of data
US6065018A (en) * 1998-03-04 2000-05-16 International Business Machines Corporation Synchronizing recovery log having time stamp to a remote site for disaster recovery of a primary database having related hierarchial and relational databases
US6356917B1 (en) * 1998-07-17 2002-03-12 Ncr Corporation Monitoring and raising alerts for database jobs
US6553392B1 (en) * 1999-02-04 2003-04-22 Hewlett-Packard Development Company, L.P. System and method for purging database update image files after completion of associated transactions
US6728879B1 (en) * 1999-06-02 2004-04-27 Microsoft Corporation Transactional log with multi-sector log block validation

Also Published As

Publication number Publication date
EP1273304A2 (en) 2003-01-08
US6344192B1 (en) 2002-02-05
EP1273304B1 (en) 2005-05-18
EP1273304B2 (en) 2009-07-15
WO1998036768A1 (en) 1998-08-27
ES2187946T3 (es) 2003-06-16
DE69810091T2 (de) 2003-10-09
DE69810091D1 (de) 2003-01-23
ZA981478B (en) 1998-08-24
ATE295736T1 (de) 2005-06-15
EP0971728B1 (en) 2002-12-11
DE69830257T2 (de) 2006-02-02
ATE229342T1 (de) 2002-12-15
EP1273304A3 (en) 2003-04-23
US20070134718A1 (en) 2007-06-14
DE69830257T3 (de) 2009-10-15
EP0971728A1 (en) 2000-01-19
DK1273304T3 (da) 2005-09-12
DE69830257D1 (de) 2005-06-23
US20020182178A1 (en) 2002-12-05
AU6726698A (en) 1998-09-09

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