ATE196314T1 - Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheit - Google Patents
Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheitInfo
- Publication number
- ATE196314T1 ATE196314T1 AT97946405T AT97946405T ATE196314T1 AT E196314 T1 ATE196314 T1 AT E196314T1 AT 97946405 T AT97946405 T AT 97946405T AT 97946405 T AT97946405 T AT 97946405T AT E196314 T1 ATE196314 T1 AT E196314T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- methods
- angiogenesis
- alpha subunit
- preventing inflammation
- Prior art date
Links
- 102100026423 Adhesion G protein-coupled receptor E5 Human genes 0.000 title abstract 5
- 101000718243 Homo sapiens Adhesion G protein-coupled receptor E5 Proteins 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 title 1
- 230000033115 angiogenesis Effects 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2787196P | 1996-10-25 | 1996-10-25 | |
| PCT/US1997/019772 WO1998017796A2 (en) | 1996-10-25 | 1997-10-24 | Methods and compositions for inhibiting inflammation and angiogenesis comprising a mammalian cd97 alpha subunit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196314T1 true ATE196314T1 (de) | 2000-09-15 |
Family
ID=21840250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97946405T ATE196314T1 (de) | 1996-10-25 | 1997-10-24 | Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheit |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6365712B1 (de) |
| EP (1) | EP0938557B1 (de) |
| JP (1) | JP2001510987A (de) |
| AT (1) | ATE196314T1 (de) |
| AU (1) | AU5158098A (de) |
| CA (1) | CA2270154A1 (de) |
| DE (1) | DE69703121D1 (de) |
| WO (1) | WO1998017796A2 (de) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001009188A1 (en) * | 1999-07-29 | 2001-02-08 | Dyax Corp. | Binding moieties for fibrin |
| US8460367B2 (en) * | 2000-03-15 | 2013-06-11 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US20070055367A1 (en) * | 2000-03-15 | 2007-03-08 | Orbus Medical Technologies, Inc. | Medical device with coating that promotes endothelial cell adherence and differentiation |
| JP5859179B2 (ja) | 2000-03-15 | 2016-02-10 | オーバスネイチ メディカル、インコーポレイテッド | 内皮細胞接着を促進するコーティング |
| US20070141107A1 (en) * | 2000-03-15 | 2007-06-21 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
| US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
| US20030229393A1 (en) * | 2001-03-15 | 2003-12-11 | Kutryk Michael J. B. | Medical device with coating that promotes cell adherence and differentiation |
| GB0009181D0 (en) * | 2000-04-13 | 2000-05-31 | Isis Innovation | Protein |
| GB2367822A (en) * | 2000-06-19 | 2002-04-17 | Smithkline Beecham Corp | CD97 polypeptides |
| US6984373B2 (en) | 2000-12-23 | 2006-01-10 | Dyax Corp. | Fibrin binding moieties useful as imaging agents |
| BR0207297A (pt) | 2001-02-15 | 2005-04-19 | King Pharmaceuticals Inc | Composição farmacêutica em forma sólida e método de preparar uma forma de dosagem sólida de um ingrediente farmaceuticamente ativo |
| US8722654B2 (en) | 2001-03-02 | 2014-05-13 | The Brigham And Women's Hospital, Inc. | Lipoxin analogs as novel inhibitors of angiogenesis |
| EP1406698B1 (de) | 2001-03-02 | 2008-10-29 | The Brigham and Women's Hospital | Lipoxin analoge als neue inhibitoren der angiogenese |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| BRPI0307077A2 (pt) * | 2002-01-22 | 2017-06-20 | Biomatera Inc | método para secar polímeros biodegradáveis |
| EP2946666B1 (de) * | 2004-04-30 | 2017-11-15 | OrbusNeich Medical, Inc. | Medizinische vorrichtung mit beschichtung zur erfassung von genetisch veränderten zellen und anwendungsverfahren dafür |
| US7727718B2 (en) * | 2005-01-04 | 2010-06-01 | Molecular Research Center, Inc. | Reagents for storage and preparation of samples for DNA analysis |
| WO2007084500A2 (en) * | 2006-01-13 | 2007-07-26 | Advanced Bionutrition Corporation | Continuous spray-capture production system |
| US11298113B2 (en) | 2008-10-01 | 2022-04-12 | Covidien Lp | Device for needle biopsy with integrated needle protection |
| US8968210B2 (en) | 2008-10-01 | 2015-03-03 | Covidien LLP | Device for needle biopsy with integrated needle protection |
| US9186128B2 (en) | 2008-10-01 | 2015-11-17 | Covidien Lp | Needle biopsy device |
| US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
| US9332973B2 (en) | 2008-10-01 | 2016-05-10 | Covidien Lp | Needle biopsy device with exchangeable needle and integrated needle protection |
| EP2537929B1 (de) | 2010-02-17 | 2017-04-12 | Japan Tobacco, Inc. | Regulierungsfaktor für pflanzenkomponenten und verwendung davon |
| UA115373C2 (uk) | 2013-06-28 | 2017-10-25 | Амген Інк. | Стабільний рідкий склад amg 416 (велкалсетиду) |
| WO2015142675A2 (en) | 2014-03-15 | 2015-09-24 | Novartis Ag | Treatment of cancer using chimeric antigen receptor |
| WO2016014530A1 (en) | 2014-07-21 | 2016-01-28 | Novartis Ag | Combinations of low, immune enhancing. doses of mtor inhibitors and cars |
| US20180334490A1 (en) | 2014-12-03 | 2018-11-22 | Qilong H. Wu | Methods for b cell preconditioning in car therapy |
| WO2016126608A1 (en) | 2015-02-02 | 2016-08-11 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| WO2016172583A1 (en) | 2015-04-23 | 2016-10-27 | Novartis Ag | Treatment of cancer using chimeric antigen receptor and protein kinase a blocker |
| WO2017027392A1 (en) | 2015-08-07 | 2017-02-16 | Novartis Ag | Treatment of cancer using chimeric cd3 receptor proteins |
| US10711282B2 (en) | 2015-11-23 | 2020-07-14 | Novartis Ag | Optimized lentiviral transfer vectors and uses thereof |
| EP3397756B1 (de) | 2015-12-30 | 2023-03-08 | Novartis AG | Immuneffektorzelltherapien mit verbesserter wirksamkeit |
| KR20180118175A (ko) | 2016-03-04 | 2018-10-30 | 노파르티스 아게 | 다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도 |
| WO2017165683A1 (en) | 2016-03-23 | 2017-09-28 | Novartis Ag | Cell secreted minibodies and uses thereof |
| JP7497955B6 (ja) | 2016-04-15 | 2024-07-01 | ノバルティス アーゲー | 選択的タンパク質発現のための組成物および方法 |
| JP2019527696A (ja) | 2016-08-01 | 2019-10-03 | ノバルティス アーゲー | プロm2マクロファージ分子の阻害剤と組み合わせてキメラ抗原受容体を用いる癌の処置 |
| WO2018111340A1 (en) | 2016-12-16 | 2018-06-21 | Novartis Ag | Methods for determining potency and proliferative function of chimeric antigen receptor (car)-t cells |
| EP4043485A1 (de) | 2017-01-26 | 2022-08-17 | Novartis AG | Cd28-zusammensetzungen und verfahren für chimäre antigenrezeptortherapie |
| JP2020506700A (ja) | 2017-01-31 | 2020-03-05 | ノバルティス アーゲー | 多重特異性を有するキメラt細胞受容体タンパク質を用いた癌の治療 |
| US11999802B2 (en) | 2017-10-18 | 2024-06-04 | Novartis Ag | Compositions and methods for selective protein degradation |
| EP3700933A1 (de) | 2017-10-25 | 2020-09-02 | Novartis AG | Gegen cd32b gerichtete antikörper und verfahren zur verwendung davon |
| RU2020116579A (ru) | 2017-10-25 | 2021-11-25 | Новартис Аг | Способы получения клеток, экспрессирующих химерный антигенный рецептор |
| EP3784351A1 (de) | 2018-04-27 | 2021-03-03 | Novartis AG | Car-t-zelltherapien mit erhöhter wirksamkeit |
| US20210396739A1 (en) | 2018-05-01 | 2021-12-23 | Novartis Ag | Biomarkers for evaluating car-t cells to predict clinical outcome |
| EP3801769A1 (de) | 2018-05-25 | 2021-04-14 | Novartis AG | Kombinationstherapie mit therapien mit chimärem antigen-rezeptor (car) |
| WO2019237035A1 (en) | 2018-06-08 | 2019-12-12 | Intellia Therapeutics, Inc. | Compositions and methods for immunooncology |
| AR116109A1 (es) | 2018-07-10 | 2021-03-31 | Novartis Ag | Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos |
| AU2019402189B2 (en) | 2018-12-20 | 2023-04-13 | Novartis Ag | Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives |
| US20220144807A1 (en) | 2019-02-15 | 2022-05-12 | Novartis Ag | 3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof |
| BR112021015672A2 (pt) | 2019-02-15 | 2021-10-05 | Novartis Ag | Derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona substituída e usos dos mesmos |
| EP3959320A1 (de) | 2019-04-24 | 2022-03-02 | Novartis AG | Zusammensetzungen und verfahren für selektiven proteinabbau |
| CN110627903B (zh) * | 2019-10-29 | 2021-09-21 | 河南大学 | 抗cd97单克隆抗体、其可变区与恒定区序列及应用 |
| EP4076660A1 (de) | 2019-12-20 | 2022-10-26 | Novartis AG | Verwendung von anti-tgf-beta-antikörpern und checkpoint-inhibitoren zur behandlung von proliferativen erkrankungen |
| KR20230024967A (ko) | 2020-06-11 | 2023-02-21 | 노파르티스 아게 | Zbtb32 억제제 및 이의 용도 |
| JP2023531676A (ja) | 2020-06-23 | 2023-07-25 | ノバルティス アーゲー | 3-(1-オキソイソインドリン-2-イル)ピぺリジン-2,6-ジオン誘導体を含む投与レジメン |
| US20230271940A1 (en) | 2020-08-03 | 2023-08-31 | Novartis Ag | Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof |
| TW202304979A (zh) | 2021-04-07 | 2023-02-01 | 瑞士商諾華公司 | 抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途 |
| AU2022267891A1 (en) | 2021-04-27 | 2023-11-09 | Novartis Ag | Viral vector production system |
| WO2023214325A1 (en) | 2022-05-05 | 2023-11-09 | Novartis Ag | Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors |
| AU2023369684A1 (en) | 2022-10-26 | 2025-04-17 | Novartis Ag | Lentiviral formulations |
| TW202500126A (zh) | 2023-05-24 | 2025-01-01 | 美商金橘生物科技公司 | 雜環化合物及其用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT920502E (pt) * | 1996-08-09 | 2006-07-31 | Sanquin Bloedvoorziening | Metodos e meios para modificacao da activacao do complemento |
-
1997
- 1997-10-24 AU AU51580/98A patent/AU5158098A/en not_active Abandoned
- 1997-10-24 DE DE69703121T patent/DE69703121D1/de not_active Expired - Lifetime
- 1997-10-24 CA CA002270154A patent/CA2270154A1/en not_active Abandoned
- 1997-10-24 AT AT97946405T patent/ATE196314T1/de not_active IP Right Cessation
- 1997-10-24 US US09/284,819 patent/US6365712B1/en not_active Expired - Fee Related
- 1997-10-24 EP EP97946405A patent/EP0938557B1/de not_active Expired - Lifetime
- 1997-10-24 JP JP51974798A patent/JP2001510987A/ja active Pending
- 1997-10-24 WO PCT/US1997/019772 patent/WO1998017796A2/en not_active Ceased
-
2002
- 2002-01-29 US US10/059,506 patent/US6846911B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998017796A2 (en) | 1998-04-30 |
| CA2270154A1 (en) | 1998-04-30 |
| EP0938557B1 (de) | 2000-09-13 |
| US6846911B2 (en) | 2005-01-25 |
| US20020168361A1 (en) | 2002-11-14 |
| AU5158098A (en) | 1998-05-15 |
| DE69703121D1 (de) | 2000-10-19 |
| US6365712B1 (en) | 2002-04-02 |
| JP2001510987A (ja) | 2001-08-07 |
| WO1998017796A3 (en) | 1998-07-09 |
| EP0938557A2 (de) | 1999-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |