DK1159296T3 - Fremgangsmåde til fremstilling af cyclo-(Asp-DPhe-NMeVal-Arg-Gly) - Google Patents

Fremgangsmåde til fremstilling af cyclo-(Asp-DPhe-NMeVal-Arg-Gly)

Info

Publication number: DK1159296T3
Authority: DK; Denmark
Prior art keywords: nmeval; dphe; cyclo; gly; asp
Prior art date: 1999-03-11

Application number

DK00920461T

Other languages

English (en)

Inventor

Alfred Jonczyk

Markus Arnold

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-11

Filing date

2000-03-01

Publication date

2004-09-27

2000-03-01 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

2004-09-27 Application granted granted Critical

2004-09-27 Publication of DK1159296T3 publication Critical patent/DK1159296T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C07K5/06095—Arg-amino acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK00920461T 1999-03-11 2000-03-01 Fremgangsmåde til fremstilling af cyclo-(Asp-DPhe-NMeVal-Arg-Gly) DK1159296T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19910727		1999-03-11

Publications (1)

Publication Number	Publication Date
DK1159296T3 true DK1159296T3 (da)	2004-09-27

Family

ID=7900511

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00920461T DK1159296T3 (da)	1999-03-11	2000-03-01	Fremgangsmåde til fremstilling af cyclo-(Asp-DPhe-NMeVal-Arg-Gly)

Country Status (28)

Country	Link
US (1)	US6822074B1 (da)
EP (1)	EP1159296B1 (da)
JP (1)	JP4762418B2 (da)
KR (1)	KR100645002B1 (da)
CN (1)	CN1200947C (da)
AR (1)	AR022905A1 (da)
AT (1)	ATE267839T1 (da)
AU (1)	AU762540B2 (da)
BR (1)	BR0008863A (da)
CA (1)	CA2366694C (da)
CZ (1)	CZ299879B6 (da)
DE (1)	DE50006598D1 (da)
DK (1)	DK1159296T3 (da)
ES (1)	ES2221616T3 (da)
HK (1)	HK1044780B (da)
HU (1)	HUP0200369A3 (da)
ID (1)	ID30126A (da)
MY (1)	MY120083A (da)
NO (1)	NO330030B1 (da)
PL (1)	PL202996B1 (da)
PT (1)	PT1159296E (da)
RU (1)	RU2243974C2 (da)
SE (1)	SE1159296T5 (da)
SK (1)	SK285387B6 (da)
TW (1)	TWI269798B (da)
UA (1)	UA71608C2 (da)
WO (1)	WO2000053627A1 (da)
ZA (1)	ZA200108335B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0814519D0 (en)	2008-08-08	2008-09-17	Imp Innovations Ltd	Process
US20120058905A1 (en) *	2009-05-15	2012-03-08	Covello Patrick S	DNA Sequences Encoding Caryophyllaceae and Caryophyllaceae-Like Cyclopeptide Precursors and Methods of Use
EP2432801B1 (en) *	2009-05-20	2016-03-23	Merck Patent GmbH	Novel solid materials of {[2s, 5r,8s,11s)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid} and methods for obtaining them
WO2011069629A2 (en)	2009-12-10	2011-06-16	Merck Patent Gmbh	Pharmaceutical composition comprising oligopeptides
CA2838573A1 (en)	2011-06-09	2012-12-13	Simon Goodman	Treatment of cancers and metastases with suspensions of cilengitide in carrier
WO2019234108A1 (en) *	2018-06-05	2019-12-12	Dsm Ip Assets B.V.	Methods for the synthesis of arginine-containing peptides

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1038741B (de) *	1956-09-14	1958-09-11	Eberhard Brecklinghaus	Aus Gummi oder einem anderen elastischen Werkstoff bestehender Kantenschoner fuer Treppenstufen aus Beton od. dgl.
US3630660A (en) *	1968-10-31	1971-12-28	Burlington Industries Inc	Process for removal of moisture and/or solvents from textile materials
UA43823C2 (uk) *	1992-07-06	2002-01-15	Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг	ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН
JPH06263798A (ja) *	1993-01-13	1994-09-20	Takeda Chem Ind Ltd	βターン及びγターンを有する環状ペンタペプチド、その製造方法および用途
EP0606881B1 (en)	1993-01-13	1999-05-12	Takeda Chemical Industries, Ltd.	Cyclic pentapeptides having a beta-turn and a gamma-turn
DE4310643A1 (de)	1993-04-01	1994-10-06	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren
AU2671795A (en) *	1994-06-02	1996-01-04	Boehringer Mannheim Gmbh	Process and intermediate products for preparing cardiodilatin fragments, and highly purified cardiodilatin fragments
WO1997045447A1 (en) *	1996-05-31	1997-12-04	The Scripps Research Institute	METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF αvβ5 MEDIATED ANGIOGENESIS
DE19534177A1 (de)	1995-09-15	1997-03-20	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren
DE19538741A1 (de)	1995-10-18	1997-04-24	Merck Patent Gmbh	Cyclopeptidderivate
DE19613933A1 (de)	1996-04-06	1997-10-09	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren
DE19728524A1 (de)	1997-07-04	1999-01-07	Merck Patent Gmbh	Cyclische Azapeptide

2000
- 2000-01-03 UA UA2001106897A patent/UA71608C2/uk unknown
- 2000-03-01 KR KR1020017011291A patent/KR100645002B1/ko not_active IP Right Cessation
- 2000-03-01 PT PT00920461T patent/PT1159296E/pt unknown
- 2000-03-01 DE DE50006598T patent/DE50006598D1/de not_active Expired - Lifetime
- 2000-03-01 AT AT00920461T patent/ATE267839T1/de active
- 2000-03-01 ID IDW00200102095A patent/ID30126A/id unknown
- 2000-03-01 CN CNB008048746A patent/CN1200947C/zh not_active Expired - Fee Related
- 2000-03-01 ES ES00920461T patent/ES2221616T3/es not_active Expired - Lifetime
- 2000-03-01 SK SK1255-2001A patent/SK285387B6/sk not_active IP Right Cessation
- 2000-03-01 WO PCT/EP2000/001751 patent/WO2000053627A1/de active IP Right Grant
- 2000-03-01 CZ CZ20013214A patent/CZ299879B6/cs not_active IP Right Cessation
- 2000-03-01 EP EP00920461A patent/EP1159296B1/de not_active Expired - Lifetime
- 2000-03-01 BR BR0008863-3A patent/BR0008863A/pt active Search and Examination
- 2000-03-01 PL PL349646A patent/PL202996B1/pl not_active IP Right Cessation
- 2000-03-01 US US09/936,230 patent/US6822074B1/en not_active Expired - Fee Related
- 2000-03-01 SE SE00820481T patent/SE1159296T5/xx unknown
- 2000-03-01 MY MYPI20000799A patent/MY120083A/en unknown
- 2000-03-01 AU AU41034/00A patent/AU762540B2/en not_active Ceased
- 2000-03-01 RU RU2001126541/04A patent/RU2243974C2/ru not_active IP Right Cessation
- 2000-03-01 DK DK00920461T patent/DK1159296T3/da active
- 2000-03-01 JP JP2000604062A patent/JP4762418B2/ja not_active Expired - Fee Related
- 2000-03-01 HU HU0200369A patent/HUP0200369A3/hu unknown
- 2000-03-01 CA CA2366694A patent/CA2366694C/en not_active Expired - Fee Related
- 2000-03-07 TW TW089104103A patent/TWI269798B/zh not_active IP Right Cessation
- 2000-03-10 AR ARP000101079A patent/AR022905A1/es active IP Right Grant
2001
- 2001-09-10 NO NO20014383A patent/NO330030B1/no not_active IP Right Cessation
- 2001-10-10 ZA ZA200108335A patent/ZA200108335B/en unknown
2002
- 2002-08-29 HK HK02106365.2A patent/HK1044780B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP2002539137A (ja)	2002-11-19
NO330030B1 (no)	2011-02-07
SK12552001A3 (sk)	2002-05-09
KR100645002B1 (ko)	2006-11-10
JP4762418B2 (ja)	2011-08-31
US6822074B1 (en)	2004-11-23
HK1044780B (zh)	2005-08-26
NO20014383L (no)	2001-11-02
HUP0200369A2 (en)	2002-06-29
SK285387B6 (sk)	2006-12-07
UA71608C2 (en)	2004-12-15
ZA200108335B (en)	2003-01-10
PT1159296E (pt)	2004-10-29
CN1343220A (zh)	2002-04-03
SE1159296T3 (da)	2004-08-24
DE50006598D1 (de)	2004-07-01
HUP0200369A3 (en)	2002-09-30
ES2221616T3 (es)	2005-01-01
CN1200947C (zh)	2005-05-11
CA2366694A1 (en)	2000-09-14
BR0008863A (pt)	2002-01-02
EP1159296A1 (de)	2001-12-05
KR20010102503A (ko)	2001-11-15
AU762540B2 (en)	2003-06-26
NO20014383D0 (no)	2001-09-10
MY120083A (en)	2005-08-30
TWI269798B (en)	2007-01-01
CA2366694C (en)	2010-07-20
PL202996B1 (pl)	2009-08-31
ATE267839T1 (de)	2004-06-15
CZ20013214A3 (cs)	2001-12-12
AR022905A1 (es)	2002-09-04
EP1159296B1 (de)	2004-05-26
ID30126A (id)	2001-11-08
SE1159296T5 (da)	2004-09-07
HK1044780A1 (en)	2002-11-01
RU2243974C2 (ru)	2005-01-10
AU4103400A (en)	2000-09-28
CZ299879B6 (cs)	2008-12-17
WO2000053627A1 (de)	2000-09-14

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