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DK1106178T3 - Anvendelse af ibudilast til fremstilling af et lægemiddel til behandling af dissemineret sklerose - Google Patents

Anvendelse af ibudilast til fremstilling af et lægemiddel til behandling af dissemineret sklerose

Info

Publication number
DK1106178T3
DK1106178T3 DK98936715T DK98936715T DK1106178T3 DK 1106178 T3 DK1106178 T3 DK 1106178T3 DK 98936715 T DK98936715 T DK 98936715T DK 98936715 T DK98936715 T DK 98936715T DK 1106178 T3 DK1106178 T3 DK 1106178T3
Authority
DK
Denmark
Prior art keywords
ibudilast
treatment
medicament
manufacture
disseminated sclerosis
Prior art date
Application number
DK98936715T
Other languages
English (en)
Inventor
Saburo Sakoda
Original Assignee
Kyorin Seiyaku Kk
Saburo Sakoda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk, Saburo Sakoda filed Critical Kyorin Seiyaku Kk
Application granted granted Critical
Publication of DK1106178T3 publication Critical patent/DK1106178T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Forklifts And Lifting Vehicles (AREA)
  • Medicinal Preparation (AREA)
DK98936715T 1998-08-10 1998-08-10 Anvendelse af ibudilast til fremstilling af et lægemiddel til behandling af dissemineret sklerose DK1106178T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1998/003548 WO2000009127A1 (fr) 1998-08-10 1998-08-10 Traitements contre la sclerose en plaques

Publications (1)

Publication Number Publication Date
DK1106178T3 true DK1106178T3 (da) 2005-02-28

Family

ID=14208769

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98936715T DK1106178T3 (da) 1998-08-10 1998-08-10 Anvendelse af ibudilast til fremstilling af et lægemiddel til behandling af dissemineret sklerose

Country Status (11)

Country Link
US (1) US6395747B1 (da)
EP (1) EP1106178B1 (da)
JP (1) JP4828003B2 (da)
AT (1) ATE283047T1 (da)
AU (1) AU8562198A (da)
CA (1) CA2339934C (da)
DE (1) DE69827853T2 (da)
DK (1) DK1106178T3 (da)
ES (1) ES2231998T3 (da)
PT (1) PT1106178E (da)
WO (1) WO2000009127A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060106054A1 (en) * 2002-12-03 2006-05-18 Michiaki Nagasawa Phosphodiesterase 10a inhibitors
DE602004031356D1 (de) * 2003-11-21 2011-03-24 Zalicus Inc Verfahren und reagenzien zur behandlung von entzündlichen erkrankungen
US20060093578A1 (en) * 2004-11-04 2006-05-04 Kyorin Pharmaceutical Co., Ltd. Method and composition for treating multiple sclerosis
MX2007006777A (es) * 2004-12-06 2007-08-06 Avigen Inc Ibudilast para tratar dolor neuropatico y sindromes asociados.
KR100780479B1 (ko) 2006-05-08 2007-11-28 윈셋파마 주식회사 이부딜라스트 함유 경구용 제제 및 이의 제조방법
EP2026804A1 (en) * 2006-05-31 2009-02-25 Avigen, Inc. Ibudilast for inhibiting macrophage migration inhibitory factor (mif) activity
PT2131841E (pt) * 2007-01-30 2012-09-24 Univ Colorado Regents Métodos para tratar a dor aguda e sub-crónica
US20080287402A1 (en) * 2007-05-03 2008-11-20 Johnson Kirk W Use of a glial attenuator to prevent amplified pain responses caused by glial priming
PL2187882T3 (pl) 2007-07-11 2013-05-31 Medicinova Inc Leczenie postępującej choroby neurodegeneracyjnej ibudilastem
US10391085B2 (en) 2016-12-22 2019-08-27 Medicinova, Inc. Methods of treating glioblastoma multiforme using ibudilast
JP2021512921A (ja) 2018-02-12 2021-05-20 メディシノバ・インコーポレイテッドＭｅｄｉｃｉＮｏｖａ， Ｉｎｃ． 癌療法に対するイブジラストおよび第二の薬剤を使用した方法ならびに投与レジメン
WO2019157428A1 (en) * 2018-02-12 2019-08-15 Medicinova, Inc. Methods of suppressing myeloid-derived suppressor cells in patients
EP3773562A1 (en) * 2018-04-05 2021-02-17 Universiteit Hasselt Selective pde4d inhibitors against demyelinating diseases
WO2020076809A1 (en) 2018-10-09 2020-04-16 Medicinova, Inc. Combination of ibudilast and interferon-beta and methods of using same
WO2020081941A1 (en) 2018-10-19 2020-04-23 Medicinova, Inc. Methods of treating ophthalmic disease/disorder or injury with ibudilast
WO2020251748A1 (en) * 2019-06-11 2020-12-17 Yale University Novel treatment for wolfram syndrome
JP2022549137A (ja) 2019-09-23 2022-11-24 メディシノバ・インコーポレイテッド イブジラスト経口製剤およびその使用方法
CN115335049A (zh) 2020-04-06 2022-11-11 美迪诺亚公司 降低患者中巨噬细胞迁移抑制因子的血浆水平的方法
CN116887829A (zh) 2021-01-29 2023-10-13 美迪诺亚公司 治疗化学气体暴露的方法
CN117940128A (zh) 2021-07-26 2024-04-26 美迪诺亚公司 异丁司特用于防止眼癌转移
CA3231869A1 (en) 2021-09-21 2023-03-30 Medicinova, Inc. Ibudilast in combination therapy for use in the treatment of glioblastoma
US12042485B2 (en) 2021-10-07 2024-07-23 Medicinova, Inc. Methods of minimizing cancer metastasis
EP4472631A1 (en) 2022-02-01 2024-12-11 MediciNova, Inc. Ibudilast for use in the treatment of post-covid conditions
WO2024015415A1 (en) 2022-07-13 2024-01-18 Medicinova, Inc. Injectable formulations of ibudilast

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672622A (en) * 1994-04-21 1997-09-30 Berlex Laboratories, Inc. Treatment of multiple sclerosis
CN1043993C (zh) * 1994-08-29 1999-07-07 山之内制药株式会社 萘啶衍生物及其医药组合物

Also Published As

Publication number Publication date
EP1106178A4 (en) 2001-11-21
US6395747B1 (en) 2002-05-28
EP1106178B1 (en) 2004-11-24
CA2339934C (en) 2008-06-03
PT1106178E (pt) 2005-02-28
DE69827853T2 (de) 2005-12-08
EP1106178A1 (en) 2001-06-13
WO2000009127A1 (fr) 2000-02-24
AU8562198A (en) 2000-03-06
ES2231998T3 (es) 2005-05-16
JP4828003B2 (ja) 2011-11-30
DE69827853D1 (de) 2004-12-30
ATE283047T1 (de) 2004-12-15
CA2339934A1 (en) 2000-02-24

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