DE69827853D1 - Verwendung von ibudilast zur herstellung eines arzneimittels zur behandlung multiple sklerose - Google Patents
Verwendung von ibudilast zur herstellung eines arzneimittels zur behandlung multiple skleroseInfo
- Publication number
- DE69827853D1 DE69827853D1 DE69827853T DE69827853T DE69827853D1 DE 69827853 D1 DE69827853 D1 DE 69827853D1 DE 69827853 T DE69827853 T DE 69827853T DE 69827853 T DE69827853 T DE 69827853T DE 69827853 D1 DE69827853 D1 DE 69827853D1
- Authority
- DE
- Germany
- Prior art keywords
- ibudilast
- multiple sclerosis
- producing
- medicinal product
- treating multiple
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Forklifts And Lifting Vehicles (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP1998/003548 WO2000009127A1 (fr) | 1998-08-10 | 1998-08-10 | Traitements contre la sclerose en plaques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69827853D1 true DE69827853D1 (de) | 2004-12-30 |
| DE69827853T2 DE69827853T2 (de) | 2005-12-08 |
Family
ID=14208769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69827853T Expired - Lifetime DE69827853T2 (de) | 1998-08-10 | 1998-08-10 | Verwendung von Ibudilast zur Herstellung eines Arzneimittels zur Behandlung von multipler Sklerose |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6395747B1 (de) |
| EP (1) | EP1106178B1 (de) |
| JP (1) | JP4828003B2 (de) |
| AT (1) | ATE283047T1 (de) |
| AU (1) | AU8562198A (de) |
| CA (1) | CA2339934C (de) |
| DE (1) | DE69827853T2 (de) |
| DK (1) | DK1106178T3 (de) |
| ES (1) | ES2231998T3 (de) |
| PT (1) | PT1106178E (de) |
| WO (1) | WO2000009127A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4589122B2 (ja) * | 2002-12-03 | 2010-12-01 | 杏林製薬株式会社 | ホスホジエステラーゼ１０ａ阻害剤 |
| DE602004031356D1 (de) * | 2003-11-21 | 2011-03-24 | Zalicus Inc | Verfahren und reagenzien zur behandlung von entzündlichen erkrankungen |
| US20060093578A1 (en) * | 2004-11-04 | 2006-05-04 | Kyorin Pharmaceutical Co., Ltd. | Method and composition for treating multiple sclerosis |
| BRPI0518829A2 (pt) * | 2004-12-06 | 2008-12-09 | Avigen Inc | mÉtodo para o tratamento de dor neuropÁtica e sÍndromes associadas |
| KR100780479B1 (ko) | 2006-05-08 | 2007-11-28 | 윈셋파마 주식회사 | 이부딜라스트 함유 경구용 제제 및 이의 제조방법 |
| US7622256B2 (en) * | 2006-05-31 | 2009-11-24 | Avigen, Inc. | Method for selecting compounds that modulate MIF-induced expression of ICAM-1 and/or VCAM-1 |
| DK2131841T3 (da) * | 2007-01-30 | 2012-10-15 | Avigen Inc | Fremgangsmåder til behandling af akut smerte |
| US20080287402A1 (en) * | 2007-05-03 | 2008-11-20 | Johnson Kirk W | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
| CN101848712B (zh) * | 2007-07-11 | 2013-07-24 | 美迪诺亚公司 | 用异丁地特治疗渐进性神经变性疾病 |
| JP2020504721A (ja) | 2016-12-22 | 2020-02-13 | メディシノバ・インコーポレイテッドＭｅｄｉｃｉＮｏｖａ， Ｉｎｃ． | イブジラストを使用した多形膠芽腫の治療方法 |
| US10744123B2 (en) | 2018-02-12 | 2020-08-18 | Medicinova, Inc. | Methods and dosing regimens using ibudilast and a second agent for cancer therapy |
| EP3740205B1 (de) * | 2018-02-12 | 2023-09-20 | MediciNova, Inc. | Verfahren zur unterdrückung von myeloidabgeleiteten suppressorzellen in patienten |
| EP3773562A1 (de) * | 2018-04-05 | 2021-02-17 | Universiteit Hasselt | Selektive pde4d-inhibitoren gegen demyelinisierende krankheiten |
| US10946071B2 (en) | 2018-10-09 | 2021-03-16 | Medicinova, Inc. | Combination of ibudilast and interferon-beta and methods of using same |
| WO2020081941A1 (en) | 2018-10-19 | 2020-04-23 | Medicinova, Inc. | Methods of treating ophthalmic disease/disorder or injury with ibudilast |
| US20220347159A1 (en) * | 2019-06-11 | 2022-11-03 | Yale University | Novel treatment for wolfram syndrome |
| US11865214B2 (en) | 2019-09-23 | 2024-01-09 | Medicinova, Inc. | Ibudilast oral formulations and methods of using same |
| EP4132521A1 (de) | 2020-04-06 | 2023-02-15 | MediciNova, Inc. | Verfahren zur reduzierung des plasmaspiegels des makrophagen-migrationshemmenden faktors bei patienten mit ibudilast |
| WO2022164948A1 (en) | 2021-01-29 | 2022-08-04 | Medicinova, Inc. | Methods of treating chemical gas exposure |
| US12005049B2 (en) | 2021-07-26 | 2024-06-11 | Medicinova, Inc. | Methods of preventing cancer metastasis |
| CA3231869A1 (en) | 2021-09-21 | 2023-03-30 | Medicinova, Inc. | Ibudilast in combination therapy for use in the treatment of glioblastoma |
| US12042485B2 (en) | 2021-10-07 | 2024-07-23 | Medicinova, Inc. | Methods of minimizing cancer metastasis |
| US12171752B2 (en) | 2022-02-01 | 2024-12-24 | Medicinova, Inc. | Methods of treating post-COVID condition(s) |
| US20240016729A1 (en) | 2022-07-13 | 2024-01-18 | Medicinova, Inc. | Injectable formulations of ibudilast |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5672622A (en) * | 1994-04-21 | 1997-09-30 | Berlex Laboratories, Inc. | Treatment of multiple sclerosis |
| NZ291507A (en) * | 1994-08-29 | 1997-12-19 | Yamanouchi Pharma Co Ltd | 1,8-naphthyridine derivatives; medicaments |
-
1998
- 1998-08-10 WO PCT/JP1998/003548 patent/WO2000009127A1/ja active IP Right Grant
- 1998-08-10 AT AT98936715T patent/ATE283047T1/de active
- 1998-08-10 PT PT98936715T patent/PT1106178E/pt unknown
- 1998-08-10 AU AU85621/98A patent/AU8562198A/en not_active Abandoned
- 1998-08-10 JP JP53649998A patent/JP4828003B2/ja not_active Expired - Lifetime
- 1998-08-10 DK DK98936715T patent/DK1106178T3/da active
- 1998-08-10 EP EP98936715A patent/EP1106178B1/de not_active Expired - Lifetime
- 1998-08-10 DE DE69827853T patent/DE69827853T2/de not_active Expired - Lifetime
- 1998-08-10 CA CA002339934A patent/CA2339934C/en not_active Expired - Lifetime
- 1998-08-10 US US09/762,616 patent/US6395747B1/en not_active Expired - Lifetime
- 1998-08-10 ES ES98936715T patent/ES2231998T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1106178E (pt) | 2005-02-28 |
| US6395747B1 (en) | 2002-05-28 |
| DK1106178T3 (da) | 2005-02-28 |
| EP1106178A1 (de) | 2001-06-13 |
| CA2339934A1 (en) | 2000-02-24 |
| DE69827853T2 (de) | 2005-12-08 |
| WO2000009127A1 (fr) | 2000-02-24 |
| AU8562198A (en) | 2000-03-06 |
| JP4828003B2 (ja) | 2011-11-30 |
| EP1106178B1 (de) | 2004-11-24 |
| ATE283047T1 (de) | 2004-12-15 |
| CA2339934C (en) | 2008-06-03 |
| ES2231998T3 (es) | 2005-05-16 |
| EP1106178A4 (de) | 2001-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |