DK1007686T3 - Tuberkulosevaccine - Google Patents
TuberkulosevaccineInfo
- Publication number
- DK1007686T3 DK1007686T3 DK98947427T DK98947427T DK1007686T3 DK 1007686 T3 DK1007686 T3 DK 1007686T3 DK 98947427 T DK98947427 T DK 98947427T DK 98947427 T DK98947427 T DK 98947427T DK 1007686 T3 DK1007686 T3 DK 1007686T3
- Authority
- DK
- Denmark
- Prior art keywords
- nucleic acid
- acid molecules
- present
- tuberculosis vaccine
- novel recombinant
- Prior art date
Links
- 229960002109 tuberculosis vaccine Drugs 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 108010008038 Synthetic Vaccines Proteins 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229940124551 recombinant vaccine Drugs 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97114614A EP0902086A1 (en) | 1997-08-22 | 1997-08-22 | Tuberculosis vaccine |
| PCT/EP1998/005109 WO1999010496A1 (en) | 1997-08-22 | 1998-08-12 | Tuberculosis vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1007686T3 true DK1007686T3 (da) | 2007-04-10 |
Family
ID=8227261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98947427T DK1007686T3 (da) | 1997-08-22 | 1998-08-12 | Tuberkulosevaccine |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6673353B1 (da) |
| EP (2) | EP0902086A1 (da) |
| JP (1) | JP4255209B2 (da) |
| AT (1) | ATE347599T1 (da) |
| AU (1) | AU9435098A (da) |
| CA (1) | CA2301879C (da) |
| CY (1) | CY1106350T1 (da) |
| DE (1) | DE69836588T2 (da) |
| DK (1) | DK1007686T3 (da) |
| ES (1) | ES2274580T3 (da) |
| PT (1) | PT1007686E (da) |
| SI (1) | SI1007686T1 (da) |
| WO (1) | WO1999010496A1 (da) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8956621B2 (en) | 1994-11-08 | 2015-02-17 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical dysplasia |
| US7820180B2 (en) * | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
| US8114414B2 (en) | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
| US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| US7794729B2 (en) | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
| US6051237A (en) * | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
| US7662396B2 (en) | 2001-03-26 | 2010-02-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| US7635479B2 (en) | 2000-03-29 | 2009-12-22 | The Trustees Of The University Of Pennsylvania | Composition and methods for enhancing immunogenecity of antigens |
| MXPA01004469A (es) | 1998-11-04 | 2002-08-30 | Isis Innovation | Prueba de diagnostico para la tuberculosis. |
| GB0006693D0 (en) * | 2000-03-20 | 2000-05-10 | Glaxo Group Ltd | Vaccine |
| US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| US6855320B2 (en) | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
| US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
| US7700344B2 (en) | 2001-03-26 | 2010-04-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| JP4545151B2 (ja) * | 2003-02-06 | 2010-09-15 | シーラス コーポレイション | 非食細胞中への侵入について減弱化されているリステリア、そのリステリアを含むワクチン、およびそれらの使用法 |
| DE602004028000D1 (de) | 2003-04-23 | 2010-08-19 | Max Planck Gesellschaft | Tuberkulose vaccine mit verbesserter effizienz |
| EP1649869A1 (en) * | 2004-10-21 | 2006-04-26 | Vakzine Projekt Management GmbH | Combination of a recombinant mycobacterium and a biologically active agent as a vaccine |
| ZA200704765B (en) * | 2004-12-01 | 2008-09-25 | Aeras Global Tb Vaccine Found | Recombinant BCG strains with enhanced ability to escape the endosome |
| EP3284478A1 (en) | 2006-08-15 | 2018-02-21 | The Trustees of the University of Pennsylvania | Compositions comprising hmw-maa and fragments thereof for treating cancer |
| US8268326B2 (en) | 2006-08-15 | 2012-09-18 | The Trustees Of The University Of Pennsylvania | Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof |
| US20110129499A1 (en) | 2008-05-19 | 2011-06-02 | Paulo Maciag | Dual delivery system for heterologous antigens |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| US8778329B2 (en) | 2009-03-04 | 2014-07-15 | The Trustees Of The University Of Pennsylvania | Compositions comprising angiogenic factors and methods of use thereof |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| CN103118703A (zh) | 2010-09-20 | 2013-05-22 | 疫苗项目管理有限公司 | 作为人用疫苗的重组分枝杆菌 |
| CN103282048B (zh) | 2010-10-01 | 2017-05-17 | 宾夕法尼亚大学理事会 | 李斯特菌疫苗载体用于在寄生虫感染的个体中扭转免疫无应答的用途 |
| EP2656070B9 (en) * | 2010-12-21 | 2017-01-04 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Determination of the efficacy of a live recombinant anti-mycobacterial vaccination |
| CN103354747A (zh) | 2010-12-21 | 2013-10-16 | 马普科技促进协会 | 作为疫苗的重组分枝杆菌 |
| EP3332804A1 (en) | 2011-03-11 | 2018-06-13 | Advaxis, Inc. | Listeria-based adjuvants |
| BR102012003790A2 (pt) | 2012-02-17 | 2014-04-22 | Fundacao Butantan | Cepa de mycobacterium recombinante, composição imunogênica e uso |
| KR20140134695A (ko) | 2012-03-12 | 2014-11-24 | 어드박시스, 인크. | 리스테리아 백신 치료 후 억제 세포 기능 저해 |
| CA2867516A1 (en) * | 2012-04-02 | 2013-10-10 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium for induction of cellular immune response |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5504005A (en) * | 1987-03-02 | 1996-04-02 | Albert Einstein College Of Medicine Of Yeshiva University | Recombinant mycobacterial vaccine |
-
1997
- 1997-08-22 EP EP97114614A patent/EP0902086A1/en not_active Withdrawn
-
1998
- 1998-08-12 DK DK98947427T patent/DK1007686T3/da active
- 1998-08-12 PT PT98947427T patent/PT1007686E/pt unknown
- 1998-08-12 ES ES98947427T patent/ES2274580T3/es not_active Expired - Lifetime
- 1998-08-12 DE DE69836588T patent/DE69836588T2/de not_active Expired - Lifetime
- 1998-08-12 SI SI9830871T patent/SI1007686T1/sl unknown
- 1998-08-12 JP JP2000507804A patent/JP4255209B2/ja not_active Expired - Lifetime
- 1998-08-12 US US09/485,717 patent/US6673353B1/en not_active Expired - Lifetime
- 1998-08-12 AU AU94350/98A patent/AU9435098A/en not_active Abandoned
- 1998-08-12 AT AT98947427T patent/ATE347599T1/de active
- 1998-08-12 WO PCT/EP1998/005109 patent/WO1999010496A1/en active IP Right Grant
- 1998-08-12 EP EP98947427A patent/EP1007686B1/en not_active Expired - Lifetime
- 1998-08-12 CA CA2301879A patent/CA2301879C/en not_active Expired - Lifetime
-
2007
- 2007-03-01 CY CY20071100297T patent/CY1106350T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2274580T3 (es) | 2007-05-16 |
| JP2001514000A (ja) | 2001-09-11 |
| DE69836588T2 (de) | 2007-04-05 |
| EP1007686B1 (en) | 2006-12-06 |
| SI1007686T1 (sl) | 2007-04-30 |
| WO1999010496A1 (en) | 1999-03-04 |
| JP4255209B2 (ja) | 2009-04-15 |
| CA2301879C (en) | 2014-02-04 |
| AU9435098A (en) | 1999-03-16 |
| ATE347599T1 (de) | 2006-12-15 |
| PT1007686E (pt) | 2007-03-30 |
| CA2301879A1 (en) | 1999-03-04 |
| DE69836588D1 (de) | 2007-01-18 |
| US6673353B1 (en) | 2004-01-06 |
| CY1106350T1 (el) | 2011-10-12 |
| EP1007686A1 (en) | 2000-06-14 |
| EP0902086A1 (en) | 1999-03-17 |
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