[go: up one dir, main page]

DK0741743T3 - Cycliske neurokinin A-antagonister - Google Patents

Cycliske neurokinin A-antagonister

Info

Publication number
DK0741743T3
DK0741743T3 DK95908459T DK95908459T DK0741743T3 DK 0741743 T3 DK0741743 T3 DK 0741743T3 DK 95908459 T DK95908459 T DK 95908459T DK 95908459 T DK95908459 T DK 95908459T DK 0741743 T3 DK0741743 T3 DK 0741743T3
Authority
DK
Denmark
Prior art keywords
antagonists
neurokinin
cyclic
cyclic neurokinin
antagonism
Prior art date
Application number
DK95908459T
Other languages
Danish (da)
English (en)
Inventor
Elizabeth M Kudlacz
Thomas J Owen
Stephen H Buck
Scott L Harbeson
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of DK0741743T3 publication Critical patent/DK0741743T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK95908459T 1994-02-03 1995-01-10 Cycliske neurokinin A-antagonister DK0741743T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/191,571 US5521156A (en) 1994-02-03 1994-02-03 Cyclic neurokinin A antagonists
PCT/US1995/000296 WO1995021187A1 (en) 1994-02-03 1995-01-10 Cyclic neurokinin a antagonists

Publications (1)

Publication Number Publication Date
DK0741743T3 true DK0741743T3 (da) 1999-06-23

Family

ID=22706020

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95908459T DK0741743T3 (da) 1994-02-03 1995-01-10 Cycliske neurokinin A-antagonister

Country Status (19)

Country Link
US (1) US5521156A (zh)
EP (1) EP0741743B1 (zh)
JP (2) JPH09511490A (zh)
KR (3) KR100380873B1 (zh)
CN (1) CN1139931A (zh)
AT (1) ATE172205T1 (zh)
AU (1) AU691246B2 (zh)
CA (1) CA2182486C (zh)
DE (1) DE69505351T2 (zh)
DK (1) DK0741743T3 (zh)
ES (1) ES2123234T3 (zh)
FI (1) FI963074A0 (zh)
HU (1) HUT74383A (zh)
IL (1) IL112489A0 (zh)
MX (1) MX9603194A (zh)
NO (1) NO963255L (zh)
NZ (1) NZ279595A (zh)
WO (1) WO1995021187A1 (zh)
ZA (1) ZA95710B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830863A (en) * 1988-06-20 1998-11-03 Merrell Pharmaceuticals Inc. Neurokinin A antagonists
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
US5521156A (en) * 1994-02-03 1996-05-28 Merrell Pharmaceuticals Inc. Cyclic neurokinin A antagonists
US5879659A (en) * 1996-03-13 1999-03-09 Dupont Pharmaceuticals Company Ternary radiopharmaceutical complexes
MX9709494A (es) * 1996-12-04 1998-07-31 Pfizer Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102877A (en) * 1976-07-28 1978-07-25 Merck & Co., Inc. Cyclization of peptides
US4659691A (en) * 1985-02-08 1987-04-21 Merck & Co., Inc. Novel cyclic Hexapeptide LHRH antagonists
IT1233696B (it) * 1989-05-29 1992-04-14 Menarini Farma Ind Peptidi di sintesi antagonisti della neurochinina a. loro sali e relativi procedimenti di fabbricazione
IT1241761B (it) * 1990-08-03 1994-02-01 Menarini Farma Ind Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione
DK0528312T3 (da) * 1991-08-13 1997-12-29 Takeda Chemical Industries Ltd Cykliske peptider og anvendelse deraf
US5521156A (en) * 1994-02-03 1996-05-28 Merrell Pharmaceuticals Inc. Cyclic neurokinin A antagonists

Also Published As

Publication number Publication date
CN1139931A (zh) 1997-01-08
IL112489A0 (en) 1995-03-30
JPH09511490A (ja) 1997-11-18
AU691246B2 (en) 1998-05-14
US5521156A (en) 1996-05-28
KR100380873B1 (ko) 2003-04-18
HUT74383A (en) 1996-12-30
JP2005089471A (ja) 2005-04-07
NO963255L (no) 1996-10-02
ES2123234T3 (es) 1999-01-01
NZ279595A (en) 1997-12-19
MX9603194A (es) 1997-05-31
AU1677195A (en) 1995-08-21
DE69505351D1 (de) 1998-11-19
CA2182486C (en) 2002-10-08
FI963074L (fi) 1996-08-02
CA2182486A1 (en) 1995-08-10
KR100378726B1 (ko) 2003-10-04
WO1995021187A1 (en) 1995-08-10
EP0741743A1 (en) 1996-11-13
ZA95710B (en) 1995-10-16
ATE172205T1 (de) 1998-10-15
FI963074A0 (fi) 1996-08-02
HU9602157D0 (en) 1996-09-30
DE69505351T2 (de) 1999-06-02
NO963255D0 (no) 1996-08-02
EP0741743B1 (en) 1998-10-14
KR100380872B1 (ko) 2003-04-18

Similar Documents

Publication Publication Date Title
ES2129090T3 (es) Diazepinas triciclicas antagonistas de la vasopresina y de la oxitocina.
LV12639B (lv) Bifenilsulfonamidi ka duali angiotenzina un endotelina receptoru antagonisti
EA199700186A1 (ru) Новые дипептидные амидины, используемые в качестве ингибиторов тромбина
EA200300873A1 (ru) Новая соль сукцинат o-десметилвенлафаксина
FI960727A0 (fi) Neurokiniiniantagonisteina käyttökelpoiset heterosyklit
EA199700118A1 (ru) Трициклические диазепины в качестве антагонистов вазопрессина, способ их получения и способ лечения с использованием трициклических диазепинов
YU104690A (sh) Supstituisani imidazo-kondenzovani 6-člani heterocikli kao antagonisti angiotenzina 2
TR200001603T2 (tr) Yeni bileşikler
TR199900318T2 (xx) IL-8 resept�r antagonistleri.
NO893431D0 (no) Fremgangsmaate for fremstilling av neuropeptid y antagonister.
DE3782999D1 (de) Bohrloch-zementierungszusammensetzungen.
FR2799148B3 (fr) Agrafeuse avec indication de la quantite d'agrafes restantes
ES2107284T3 (es) Nuevas n-piridil-carboxamidas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ATE401894T1 (de) Verwendung von 15-keto-prostaglandin-e verbindungen als endothelin antagonisten
DE69505351D1 (de) Zyklische neurokinin a - antagonisten
ATE259825T1 (de) Hemihydrat von 16.alpha.-bromoepiandrosterone
CA2022740A1 (en) Cyclic neurokinin a antagonists
EP0347802A3 (en) Neurokinin a antagonists
DE69805988D1 (de) Herstellung von 1,3-diaminopentan durch hydrierung von 3-aminopentanitril
MX9603199A (es) Antagonistas de receptores a endotelina.
EA199700223A1 (ru) Бициклические антагонисты тахикининов, их получение и применение в фармацевтической композиции
TR200000602T2 (tr) Yeni karbonik asit türevleri, üretimleri ve kullanımları.
ATE113949T1 (de) Alpha-adrenergische rezeptorantagonisten.
DE68905075D1 (de) Herstellung von tris(2-zyanaethyl)amin.
ATE109483T1 (de) Alpha-adrenergische rezeptorantagonisten.