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YU104690A - Supstituisani imidazo-kondenzovani 6-člani heterocikli kao antagonisti angiotenzina 2 - Google Patents

Supstituisani imidazo-kondenzovani 6-člani heterocikli kao antagonisti angiotenzina 2

Info

Publication number
YU104690A
YU104690A YU104690A YU104690A YU104690A YU 104690 A YU104690 A YU 104690A YU 104690 A YU104690 A YU 104690A YU 104690 A YU104690 A YU 104690A YU 104690 A YU104690 A YU 104690A
Authority
YU
Yugoslavia
Prior art keywords
angiotensin
antagonists
condensed
substituted
imidaso
Prior art date
Application number
YU104690A
Other languages
English (en)
Inventor
P.K. Chakravarty
W.J. Greenlee
N.B. Mantilo
A.A. Petchett
T.F. Walsh
Original Assignee
Merck & Co.Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co.Inc. filed Critical Merck & Co.Inc.
Priority to SI9011046A priority Critical patent/SI9011046A/sl
Publication of YU104690A publication Critical patent/YU104690A/sh
Priority to HRP-1046/90A priority patent/HRP930776A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SUPSTITUISANI IMIDAZO-KONDENZOVANI 6-ČLANI HETEROCIKLI KAO ANTAGONISTI ANGIOTENZINA 2 , pronalazak se odnosi na postupak za izradu imidazo-kondenzovanih 6-članih heterocikla strukturne formule: u kojoj su A,B,C i D nezavisno atomi ugljenika ili atomi azota koji su antagonisti angiotenzina II podesni za lečenje hipertenzije i kongestivne srčane mane.
YU104690A 1989-05-30 1990-05-29 Supstituisani imidazo-kondenzovani 6-člani heterocikli kao antagonisti angiotenzina 2 YU104690A (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI9011046A SI9011046A (sl) 1989-05-30 1990-05-29 Substituiraniimidazo-kondenzirani 6-členski heterocikli kot antagonisti angiotenzinaii
HRP-1046/90A HRP930776A2 (en) 1989-05-30 1993-04-02 Substituted imidazo-fused 6-membered heterocycles as angiotensin ii antagonists

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35897189A 1989-05-30 1989-05-30
US07/516,286 US5332744A (en) 1989-05-30 1990-05-04 Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists

Publications (1)

Publication Number Publication Date
YU104690A true YU104690A (sh) 1992-12-21

Family

ID=23411780

Family Applications (1)

Application Number Title Priority Date Filing Date
YU104690A YU104690A (sh) 1989-05-30 1990-05-29 Supstituisani imidazo-kondenzovani 6-člani heterocikli kao antagonisti angiotenzina 2

Country Status (4)

Country Link
US (1) US5332744A (sh)
KR (1) KR900018072A (sh)
YU (1) YU104690A (sh)
ZA (1) ZA904094B (sh)

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Also Published As

Publication number Publication date
ZA904094B (en) 1991-03-27
KR900018072A (ko) 1990-12-20
US5332744A (en) 1994-07-26

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