DK0726955T3 - Kimære proteiner, som omfatter Borreliapolypeptider, og anvendelser heraf - Google Patents
Kimære proteiner, som omfatter Borreliapolypeptider, og anvendelser herafInfo
- Publication number
- DK0726955T3 DK0726955T3 DK95900453T DK95900453T DK0726955T3 DK 0726955 T3 DK0726955 T3 DK 0726955T3 DK 95900453 T DK95900453 T DK 95900453T DK 95900453 T DK95900453 T DK 95900453T DK 0726955 T3 DK0726955 T3 DK 0726955T3
- Authority
- DK
- Denmark
- Prior art keywords
- chimeric
- proteins
- chimeric proteins
- applications
- borrelia
- Prior art date
Links
- 208000016604 Lyme disease Diseases 0.000 title abstract 4
- 241000589968 Borrelia Species 0.000 title abstract 3
- 102000037865 fusion proteins Human genes 0.000 title abstract 3
- 108020001507 fusion proteins Proteins 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14819193A | 1993-11-01 | 1993-11-01 | |
| US08/235,836 US6248562B1 (en) | 1993-11-01 | 1994-04-29 | Chimeric proteins comprising borrelia polypeptides and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0726955T3 true DK0726955T3 (da) | 2004-08-09 |
Family
ID=26845620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95900453T DK0726955T3 (da) | 1993-11-01 | 1994-10-27 | Kimære proteiner, som omfatter Borreliapolypeptider, og anvendelser heraf |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0726955B1 (da) |
| AT (1) | ATE263836T1 (da) |
| AU (1) | AU8127494A (da) |
| CA (1) | CA2175567C (da) |
| DE (1) | DE69433690T2 (da) |
| DK (1) | DK0726955T3 (da) |
| ES (1) | ES2219657T3 (da) |
| IL (1) | IL111479A0 (da) |
| PT (1) | PT726955E (da) |
| WO (1) | WO1995012676A1 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6676942B1 (en) * | 1991-08-15 | 2004-01-13 | Smithkline Beecham Biologicals (S.A.) | Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines |
| US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
| CA2193870C (en) * | 1995-12-25 | 2000-07-18 | Nobuyuki Ise | Treponema pallidum fused antigen and assay for anti-treponema pallidum antibodies using the same fused antigen |
| DE19632862B4 (de) | 1996-08-14 | 2006-08-03 | Mikrogen Molekularbiologische Entwicklungs-Gmbh | Immunologisch aktive Proteine von Borrelia burgdorferi, dafür kodierende Nukleinsäuren sowie deren Verwendung in Testkits und als Impfstoffe |
| CA2300365A1 (en) * | 1997-09-10 | 1999-03-18 | Symbicom Aktiebolag | P13 antigens from borrelia |
| DE19847142A1 (de) * | 1998-10-13 | 2000-04-27 | Max Planck Gesellschaft | Testkit zur Diagnose von Borreliosen und neue Borrelia-Antigene für die Impfstoffentwicklung |
| EP1683867B1 (en) * | 1999-06-18 | 2014-04-09 | Research Foundation Of State University Of New York | Groups of Borrelia burgdorferi and Borrelia afzelii that cause lyme disease in humans |
| AU2001281145A1 (en) * | 2000-08-18 | 2002-03-04 | Brookhaven Sciences Associates, Llc | Recombinant constructs of borrelia burgdorferi |
| DE60131982T2 (de) | 2000-08-18 | 2008-12-11 | Brookhaven Science Associates Llc | Veränderte borrelia burgdorferi ospa |
| EP1865062A3 (en) * | 2000-08-18 | 2008-01-09 | Research Foundation Of State University Of New York | Altered OspA of Borrelia burgdorferi |
| EP1939294A1 (en) * | 2000-08-18 | 2008-07-02 | Research Foundation Of State University Of New York | Recombinant constructs of borrelia burgdorferi |
| EP2155782A2 (en) | 2007-03-26 | 2010-02-24 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
| WO2009003493A2 (en) | 2007-07-03 | 2009-01-08 | Dako Denmark A/S | Mhc multimers, methods for their generation, labeling and use |
| WO2009039854A2 (en) | 2007-09-27 | 2009-04-02 | Dako Denmark A/S | Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics |
| US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
| US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
| GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| US10369204B2 (en) | 2008-10-02 | 2019-08-06 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| MX375965B (es) * | 2010-05-14 | 2025-03-07 | Baxalta Inc | Genes ospa quimericos, proteinas, y metodos para usar los mismos. |
| CA2879689A1 (en) | 2012-07-27 | 2014-01-30 | Baxter International Inc. | Compositions comprising chimeric ospa molecules and methods of use thereof |
| CZ2014320A3 (cs) * | 2014-05-09 | 2015-11-18 | VÝZKUMNÝ ÚSTAV VETERINÁRNÍHO LÉKAŘSTVÍ, v.v.i. | Polyepitopový antigen, vakcinační konstrukt a vakcína pro prevenci lymeské boreliózy |
| WO2016057562A1 (en) * | 2014-10-07 | 2016-04-14 | The Research Foundation For The State University Of New York | Recombinant borrelia proteins and methods of use thereof |
| WO2020127222A2 (en) | 2018-12-17 | 2020-06-25 | Immudex Aps | Panel comprising borrelia mhc multimers |
| US20220160856A1 (en) * | 2020-11-25 | 2022-05-26 | Lankenau Institute For Medical Research | Methods and compositions for the diagnosis, prophylaxis and treatment of lyme disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69122240T2 (de) * | 1990-03-05 | 1997-02-13 | The United States of America, represented by the Secretary, U.S. Department of Commerce, Washington, D.C. | Antigen-wirkende proteine von borrelia burgdorferi |
| EP0650527B1 (en) * | 1991-10-22 | 2003-03-12 | Symbicom Ab | Improvement in borrelia burgdorferi diagnosis and prophylaxis |
| AU6366894A (en) * | 1993-03-11 | 1994-09-26 | Regents Of The University Of California, The | Methods, compositions, and kits for diagnosing lyme disease |
-
1994
- 1994-10-27 AT AT95900453T patent/ATE263836T1/de active
- 1994-10-27 PT PT95900453T patent/PT726955E/pt unknown
- 1994-10-27 ES ES95900453T patent/ES2219657T3/es not_active Expired - Lifetime
- 1994-10-27 AU AU81274/94A patent/AU8127494A/en not_active Abandoned
- 1994-10-27 DE DE69433690T patent/DE69433690T2/de not_active Expired - Lifetime
- 1994-10-27 CA CA2175567A patent/CA2175567C/en not_active Expired - Fee Related
- 1994-10-27 EP EP95900453A patent/EP0726955B1/en not_active Expired - Lifetime
- 1994-10-27 DK DK95900453T patent/DK0726955T3/da active
- 1994-10-27 WO PCT/US1994/012352 patent/WO1995012676A1/en active IP Right Grant
- 1994-10-31 IL IL11147994A patent/IL111479A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT726955E (pt) | 2004-08-31 |
| CA2175567A1 (en) | 1995-05-11 |
| DE69433690D1 (de) | 2004-05-13 |
| IL111479A0 (en) | 1994-12-29 |
| ES2219657T3 (es) | 2004-12-01 |
| WO1995012676A1 (en) | 1995-05-11 |
| DE69433690T2 (de) | 2005-03-10 |
| EP0726955A1 (en) | 1996-08-21 |
| EP0726955B1 (en) | 2004-04-07 |
| CA2175567C (en) | 2010-08-10 |
| ATE263836T1 (de) | 2004-04-15 |
| AU8127494A (en) | 1995-05-23 |
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