DK0653942T3 - Morphogen-induceret nerve-regenerering og -reparation - Google Patents

Morphogen-induceret nerve-regenerering og -reparation

Info

Publication number: DK0653942T3
Authority: DK; Denmark
Prior art keywords: neurons; mammal; morphogen; stimulating; repair
Prior art date: 1992-07-31

Application number

DK93918560T

Other languages

English (en)

Inventor

Charles M Cohen

Hermann Oppermann

Engin Ozkaynak

Thangavel Kuberasampath

David C Rueger

Roy H L Pang

Original Assignee

Curis Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-31

Filing date

1993-07-29

Publication date

2003-10-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27363454&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0653942(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-07-29 Application filed by Curis Inc filed Critical Curis Inc

2003-10-20 Application granted granted Critical

2003-10-20 Publication of DK0653942T3 publication Critical patent/DK0653942T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Immunology (AREA)
Transplantation (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Psychiatry (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Oral & Maxillofacial Surgery (AREA)
Dermatology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Addiction (AREA)
Orthopedic Medicine & Surgery (AREA)
Toxicology (AREA)
Psychology (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)

DK93918560T 1992-07-31 1993-07-29 Morphogen-induceret nerve-regenerering og -reparation DK0653942T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US92281392A	1992-07-31	1992-07-31
US2933593A	1993-03-04	1993-03-04
US4051093A	1993-03-31	1993-03-31
PCT/US1993/007231 WO1994003200A1 (en)	1992-07-31	1993-07-29	Morphogen-induced nerve regeneration and repair

Publications (1)

Publication Number	Publication Date
DK0653942T3 true DK0653942T3 (da)	2003-10-20

Family

ID=27363454

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93918560T DK0653942T3 (da)	1992-07-31	1993-07-29	Morphogen-induceret nerve-regenerering og -reparation

Country Status (10)

Country	Link
EP (1)	EP0653942B2 (da)
JP (3)	JP4344012B2 (da)
AT (1)	ATE242639T1 (da)
AU (1)	AU681594B2 (da)
CA (1)	CA2141554C (da)
DE (1)	DE69333040T3 (da)
DK (1)	DK0653942T3 (da)
ES (1)	ES2201059T5 (da)
PT (1)	PT653942E (da)
WO (1)	WO1994003200A1 (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6150328A (en)	1986-07-01	2000-11-21	Genetics Institute, Inc.	BMP products
US6495513B1 (en)	1991-03-11	2002-12-17	Curis, Inc.	Morphogen-enhanced survival and repair of neural cells
US6723698B2 (en)	1991-03-11	2004-04-20	Curis, Inc.	Methods and compositions for the treatment of motor neuron injury and neuropathy
US6506729B1 (en)	1991-03-11	2003-01-14	Curis, Inc.	Methods and compositions for the treatment and prevention of Parkinson's disease
DE69333040T3 (de) *	1992-07-31	2007-10-11	Curis, Inc., Cambridge	Morphogen induzierte nerven wiederherstellung und wiedergutmachung.
WO1994006447A2 (en) *	1992-09-15	1994-03-31	Creative Biomolecules, Inc.	60a protein-induced morphogenesis
EP1378572B1 (en)	1993-05-12	2006-10-25	Genetics Institute, LLC	Bmp-11 compositions
AU677866B2 (en) *	1993-08-26	1997-05-08	Board Of Trustees Of The University Of Illinois, The	Neural regeneration using human bone morphogenetic proteins
US6291206B1 (en)	1993-09-17	2001-09-18	Genetics Institute, Inc.	BMP receptor proteins
EP0733109B9 (en)	1993-12-07	2006-07-05	Genetics Institute, LLC	Bmp-12, bmp-13 and tendon-inducing compositions thereof
US5669407A (en) *	1994-03-24	1997-09-23	Masco Corporation Of Indiana	Compression cartridge for a faucet valve assembly
WO1996030038A1 (en) *	1995-03-29	1996-10-03	The Rockefeller University	Peptide growth factor having epidermal inducing activity
EP1364655B1 (en)	1996-03-22	2010-12-29	Stryker Corporation	Method for enhancing functional recovery of motor coordination, speech or sensory perception after central nervous system ischemia or trauma
US6498142B1 (en)	1996-05-06	2002-12-24	Curis, Inc.	Morphogen treatment for chronic renal failure
US5928940A (en) *	1996-09-24	1999-07-27	Creative Biomolecules, Inc.	Morphogen-responsive signal transducer and methods of use thereof
AU4726597A (en) *	1996-10-31	1998-05-22	Nippon Shinyaku Co. Ltd.	Cranial nerve cell protectives
WO1998020889A1 (en) *	1996-11-15	1998-05-22	Creative Biomolecules Inc	Morphogen peptide-induced regeneration of sense perceptory tissues
PT980252E (pt) *	1997-05-05	2005-01-31	Curis Inc	Terapias para insuficiencia renal aguda
EP2309261A1 (en)	1997-05-30	2011-04-13	Stryker Corporation	Methods for evaluating tissue morphogenesis and morphogenic activity
US20030170213A1 (en) *	1998-01-23	2003-09-11	Marc F. Charette	Methods and compositions for enhancing cognitive function using morphogenic proteins
US7147839B2 (en) *	1998-05-29	2006-12-12	Curis, Inc.	Methods for evaluating tissue morphogenesis and activity
EP1131087B2 (en) †	1998-11-13	2009-04-01	Stryker Corporation	Alleviatation of prostate cancer symptoms
US6727224B1 (en)	1999-02-01	2004-04-27	Genetics Institute, Llc.	Methods and compositions for healing and repair of articular cartilage
CA2386408A1 (en)	1999-10-15	2001-04-26	Genetics Institute, Inc.	Formulations of hyaluronic acid for delivery of osteogenic proteins
TWI329129B (en)	2001-02-08	2010-08-21	Wyeth Corp	Modified and stabilized gdf propeptides and uses thereof
DE60226321T2 (de)	2001-06-01	2009-07-09	Wyeth	Zusammensetzungen für die systemische verabreichung von sequenzen, die für knochenmorphogenese-proteinen kodieren
TWI267378B (en)	2001-06-08	2006-12-01	Wyeth Corp	Calcium phosphate delivery vehicles for osteoinductive proteins
ES2397327T3 (es)	2002-06-17	2013-03-06	Thrasos, Inc.	Compuestos asociados a un dominio único de TDF y análogos de los mismos
EP2319526A1 (en)	2004-06-17	2011-05-11	Thrasos Therapeutics, Inc.	Tdf-related compounds and analogs thereof
CN101031645B (zh) *	2004-06-23	2011-06-08	组织基因股份有限公司	神经再生
WO2007035872A2 (en)	2005-09-20	2007-03-29	Thrasos Therapeutics, Inc.	Tdf-related compounds and analogs thereof
JP2011514331A (ja)	2008-02-13	2011-05-06	キースフルスカ，	血管硬化症の治療における使用のためのｂｍｐ−７
WO2010144696A1 (en)	2009-06-11	2010-12-16	Burnham Institute For Medical Research	Directed differentiation of stem cells
WO2018112362A1 (en) *	2016-12-16	2018-06-21	Biogen Ma Inc.	Stabilized proteolytically activated growth differentiation factor 11

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0723013B1 (en) *	1988-04-08	2003-06-18	Stryker Corporation	Biosynthetic osteogenic proteins and osteogenic devices containing them
CA2030518C (en) *	1989-03-28	2000-03-21	Elizabeth A. Wang	Osteoinductive compositions
ES2137931T3 (es) *	1990-06-15	2000-01-01	Carnegie Inst Of Washington	Proteinas gdf-1 y uog-1.
AU660019B2 (en) *	1991-03-11	1995-06-08	Stryker Corporation	Protein-induced morphogenesis
AU674500B2 (en) *	1991-11-04	1997-01-02	Genetics Institute, Llc	Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
DE69333040T3 (de) *	1992-07-31	2007-10-11	Curis, Inc., Cambridge	Morphogen induzierte nerven wiederherstellung und wiedergutmachung.

1993
- 1993-07-29 DE DE69333040T patent/DE69333040T3/de not_active Expired - Lifetime
- 1993-07-29 EP EP93918560A patent/EP0653942B2/en not_active Expired - Lifetime
- 1993-07-29 PT PT93918560T patent/PT653942E/pt unknown
- 1993-07-29 WO PCT/US1993/007231 patent/WO1994003200A1/en active IP Right Grant
- 1993-07-29 ES ES93918560T patent/ES2201059T5/es not_active Expired - Lifetime
- 1993-07-29 DK DK93918560T patent/DK0653942T3/da active
- 1993-07-29 AT AT93918560T patent/ATE242639T1/de not_active IP Right Cessation
- 1993-07-29 CA CA002141554A patent/CA2141554C/en not_active Expired - Fee Related
- 1993-07-29 AU AU47971/93A patent/AU681594B2/en not_active Ceased
- 1993-07-29 JP JP50548594A patent/JP4344012B2/ja not_active Expired - Lifetime
2005
- 2005-04-05 JP JP2005108242A patent/JP2005287512A/ja active Pending
2009
- 2009-05-12 JP JP2009115655A patent/JP2009227679A/ja active Pending

Also Published As

Publication number	Publication date
DE69333040T2 (de)	2004-05-06
AU681594B2 (en)	1997-09-04
CA2141554A1 (en)	1994-02-17
EP0653942B2 (en)	2007-03-07
DE69333040T3 (de)	2007-10-11
JPH07509721A (ja)	1995-10-26
EP0653942A1 (en)	1995-05-24
ES2201059T3 (es)	2004-03-16
JP4344012B2 (ja)	2009-10-14
AU4797193A (en)	1994-03-03
JP2009227679A (ja)	2009-10-08
EP0653942B1 (en)	2003-06-11
PT653942E (pt)	2003-11-28
ES2201059T5 (es)	2007-11-01
CA2141554C (en)	2003-02-11
ATE242639T1 (de)	2003-06-15
DE69333040D1 (de)	2003-07-17
WO1994003200A1 (en)	1994-02-17
JP2005287512A (ja)	2005-10-20

Publication	Publication Date	Title
DK0653942T3 (da)	2003-10-20	Morphogen-induceret nerve-regenerering og -reparation
DK0670729T3 (da)	2001-12-10	Anvendelse af insulin-lignende vækstfaktorer og analoger til behandling af retinale nervesygdomme
ES2114073T3 (es)	1998-05-16	Regeneracion del higado inducida por morfogenes.
EP1039802A4 (en)	2002-01-23	TRANSDERMAL THERAPEUTIC DEVICE AND METHOD USING CAPSAICIN AND THE LIKE
AR023400A1 (es)	2002-09-04	Metodos para inducir la muerte de celulas cancerosas y la regresion de tumores
ATE381935T1 (de)	2008-01-15	Verwendung von triacetyluridin zur behandlung von mitochondrialen erkrankungen
DE58906649D1 (de)	1994-02-17	Implantierbares medizinisches Gerät mit Mitteln zum Stimulieren von Gewebekontraktionen mit einstellbarer Stimulationsintensität und Verfahren zum Betrieb eines solchen Gerätes.
EA200200847A1 (ru)	2003-02-27	Производные пиперазина и пиперидина для лечения и профилактики поврежденных нейронов
PT950057E (pt)	2003-04-30	Enantiomeros de 3-piridilo e sua utilizacao como analgesicos
ATE323482T1 (de)	2006-05-15	Verwendung von p38 mapk inhibitoren in der behandlung von augenkrankheiten
DK0858330T3 (da)	2001-01-02	Præparater indeholdende derivater af hydroperoxyeicosatetraensyre og fremgangsmåder til anvendelse ved behandling af sygdom
ATE434975T1 (de)	2009-07-15	Vorrichtung und verfahren zur repositionierung von patienten
ATE365550T1 (de)	2007-07-15	Verwendung von einem protein kinase hemmer wie z.b. genistein bei der behandlung von diabetischer retinopathie
KR20040101220A (ko)	2004-12-02	중추신경계 신경 재생을 촉진하는 슈반 세포 브리지임플란트 및 포스포디에스테라제 저해제
FR2760369B1 (fr)	1999-04-30	Stimulateur cardiaque multisites pour le traitement des insuffisances cardiaques par stimulation
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DE69940024D1 (de)	2009-01-15	Methode zum screening von anti-amyloidogenen eigenschaften und methode zur behandlung neurodegenerativer krankheiten
EP0214017A3 (en)	1989-07-26	Use of n,n,-dimethylbiguanid p-chorophenoxyacetate in the treatment of neuropathies and nerval degeneration
BR9906926A (pt)	2002-01-15	Composições e métodos para tratamento de células tendo dna de minuto duplo
ATE359774T1 (de)	2007-05-15	Taurinderivate verwendbar in der behandlung von netzhauterkrankungen
NO20010390L (no)	2001-03-13	Behandling av angstsykdommer
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CY1108922T1 (el)	2014-07-02	Θεραπεια μελανωματος
DE69800906D1 (de)	2001-07-19	Verwendung von Olanzapine zur Herstellung eines Arzneimittels zur Behandlung der zerebralen fokalen Ischämie