DK0639225T3 - Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi - Google Patents
Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologiInfo
- Publication number
- DK0639225T3 DK0639225T3 DK93909852T DK93909852T DK0639225T3 DK 0639225 T3 DK0639225 T3 DK 0639225T3 DK 93909852 T DK93909852 T DK 93909852T DK 93909852 T DK93909852 T DK 93909852T DK 0639225 T3 DK0639225 T3 DK 0639225T3
- Authority
- DK
- Denmark
- Prior art keywords
- amino acid
- acid sequence
- polypeptides
- immunology
- inflammation
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 206010061218 Inflammation Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000005008 immunosuppressive cell Anatomy 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
- C07K2319/91—Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP92401231 | 1992-04-30 | ||
PCT/EP1993/001022 WO1993022437A1 (en) | 1992-04-30 | 1993-04-28 | New polypeptides and peptides, nucleic acids coding for them, and their use in the field of tumor therapy, inflammation or immunology |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0639225T3 true DK0639225T3 (da) | 2003-02-17 |
Family
ID=8211656
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93909852T DK0639225T3 (da) | 1992-04-30 | 1993-04-28 | Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi |
Country Status (9)
Country | Link |
---|---|
US (2) | US5981277A (da) |
EP (1) | EP0639225B1 (da) |
JP (1) | JPH07502171A (da) |
AT (1) | ATE226250T1 (da) |
DE (1) | DE69332406T2 (da) |
DK (1) | DK0639225T3 (da) |
ES (1) | ES2185630T3 (da) |
PT (1) | PT639225E (da) |
WO (1) | WO1993022437A1 (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0791061A4 (en) * | 1994-03-04 | 1998-07-15 | Ludwig Inst Cancer Res | TARGET GENE BREAKING ANIMALS |
DE19846077C2 (de) * | 1998-10-06 | 2000-09-07 | Ulrich H Goeringer | Trypanosomen-bindende Nukleinsäuren, ihre Herstellung und Verwendung |
CA2390415A1 (en) * | 1999-11-30 | 2001-06-07 | Innogenetics N.V. | New uses of suppressive macrophage activation factors |
US7329725B1 (en) | 2003-10-29 | 2008-02-12 | Nastech Pharmaceutical Company Inc. | Phage displayed Trp cage ligands |
ES2326670T3 (es) | 2004-03-30 | 2009-10-16 | Nsgene A/S | Uso terapeutico del factor de crecimiento nsg33. |
PL1957647T3 (pl) * | 2005-11-25 | 2015-07-31 | Zoetis Belgium S A | Oligorybonukleotydy immunostymulujące |
CA2730710C (en) * | 2008-07-24 | 2021-06-08 | Nsgene A/S | Therapeutic use of a growth factor, metrnl |
CN108079279B (zh) | 2010-10-01 | 2022-04-12 | 霍巴治疗公司 | 镍纹蛋白用于治疗异常性疼痛、痛觉过敏、自发性疼痛和幻痛的用途 |
CN104105501B (zh) | 2011-09-05 | 2017-10-20 | 霍巴治疗公司 | 异常性疼痛、痛觉过敏、自发性疼痛、和幻痛的治疗 |
WO2014116556A2 (en) * | 2013-01-25 | 2014-07-31 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for regulating thermogenesis and muscle inflammation using metrnl and metrn |
WO2015062167A1 (zh) * | 2013-10-29 | 2015-05-07 | 中国人民解放军第二军医大学 | Metrnl蛋白在制备降血脂降血糖药物中的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6490199A (en) * | 1987-09-30 | 1989-04-06 | Hiromi Fujiwara | T cell growth factor derived from thymic interstitial cell and production thereof |
US5049659A (en) * | 1988-02-09 | 1991-09-17 | Dana Farber Cancer Institute | Proteins which induce immunological effector cell activation and chemattraction |
-
1993
- 1993-04-28 US US08/318,837 patent/US5981277A/en not_active Expired - Fee Related
- 1993-04-28 WO PCT/EP1993/001022 patent/WO1993022437A1/en not_active Application Discontinuation
- 1993-04-28 DE DE69332406T patent/DE69332406T2/de not_active Revoked
- 1993-04-28 DK DK93909852T patent/DK0639225T3/da active
- 1993-04-28 PT PT93909852T patent/PT639225E/pt unknown
- 1993-04-28 ES ES93909852T patent/ES2185630T3/es not_active Expired - Lifetime
- 1993-04-28 JP JP5518910A patent/JPH07502171A/ja active Pending
- 1993-04-28 EP EP93909852A patent/EP0639225B1/en not_active Revoked
- 1993-04-28 AT AT93909852T patent/ATE226250T1/de not_active IP Right Cessation
-
1999
- 1999-04-19 US US09/294,121 patent/US20020069422A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE226250T1 (de) | 2002-11-15 |
DE69332406T2 (de) | 2003-06-26 |
US5981277A (en) | 1999-11-09 |
EP0639225A1 (en) | 1995-02-22 |
ES2185630T3 (es) | 2003-05-01 |
WO1993022437A1 (en) | 1993-11-11 |
EP0639225B1 (en) | 2002-10-16 |
JPH07502171A (ja) | 1995-03-09 |
US20020069422A1 (en) | 2002-06-06 |
PT639225E (pt) | 2003-03-31 |
DE69332406D1 (de) | 2002-11-21 |
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