DK0513675T3 - Hidtil ukendt peptidforbindelse samt fremgangsmåde til fremstilling deraf - Google Patents

Hidtil ukendt peptidforbindelse samt fremgangsmåde til fremstilling deraf

Info

Publication number: DK0513675T3
Authority: DK; Denmark
Prior art keywords: preparation; formula; peptide compound; carboxy; group
Prior art date: 1991-05-13

Application number

DK92107757.4T

Other languages

Danish (da)

English (en)

Inventor

Akito Tanaka

Hiroyoshi Sakai

Hisashi Takasugi

Takatoshi Ishikawa

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-05-13

Filing date

1992-05-08

Publication date

1996-09-30

1991-05-13 Priority claimed from GB919110298A external-priority patent/GB9110298D0/en

1992-02-03 Priority claimed from GB929202260A external-priority patent/GB9202260D0/en

1992-05-08 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1996-09-30 Application granted granted Critical

1996-09-30 Publication of DK0513675T3 publication Critical patent/DK0513675T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Gastroenterology & Hepatology (AREA)
Animal Behavior & Ethology (AREA)
Toxicology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

DK92107757.4T 1991-05-13 1992-05-08 Hidtil ukendt peptidforbindelse samt fremgangsmåde til fremstilling deraf DK0513675T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB919110298A GB9110298D0 (en)	1991-05-13	1991-05-13	New peptide compound and a process for the preparation thereof
GB929202260A GB9202260D0 (en)	1992-02-03	1992-02-03	New peptide compound and a process for the preparation thereof

Publications (1)

Publication Number	Publication Date
DK0513675T3 true DK0513675T3 (da)	1996-09-30

Family

ID=26298895

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92107757.4T DK0513675T3 (da)	1991-05-13	1992-05-08	Hidtil ukendt peptidforbindelse samt fremgangsmåde til fremstilling deraf

Country Status (15)

Country	Link
US (1)	US5574016A (de)
EP (1)	EP0513675B1 (de)
JP (1)	JP2606528B2 (de)
KR (1)	KR920021579A (de)
CN (2)	CN1043647C (de)
AT (1)	ATE142641T1 (de)
AU (1)	AU662522B2 (de)
CA (1)	CA2068478A1 (de)
DE (1)	DE69213546T2 (de)
DK (1)	DK0513675T3 (de)
ES (1)	ES2091359T3 (de)
GR (1)	GR3021182T3 (de)
HU (2)	HUT61780A (de)
IL (1)	IL101839A (de)
TW (1)	TW203057B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5272162A (en) *	1992-07-02	1993-12-21	G. D. Searle & Co.	Platelet aggregation inhibitors
US5354738A (en) *	1992-09-04	1994-10-11	G. D. Searle & Co.	Platelet aggregation inhibitors
US5314902A (en) *	1993-01-27	1994-05-24	Monsanto Company	Urea derivatives useful as platelet aggregation inhibitors
DE4309867A1 (de) *	1993-03-26	1994-09-29	Cassella Ag	Neue Harnstoffderivate, ihre Herstellung und Verwendung
ZW4194A1 (en) *	1993-03-29	1994-12-21	Zeneca Ltd	Heterocyclic compounds
DK0825184T3 (da) *	1993-03-29	2001-09-10	Astrazeneca Ab	Heterocykliske derivater som blodpladeaggregeringsinhibitorer
US5753659A (en) *	1993-03-29	1998-05-19	Zeneca Limited	Heterocyclic compouds
US5750754A (en) *	1993-03-29	1998-05-12	Zeneca Limited	Heterocyclic compounds
US5652242A (en) *	1993-03-29	1997-07-29	Zeneca Limited	Heterocyclic derivatives
GB9313268D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Chemical compounds
US5463011A (en) *	1993-06-28	1995-10-31	Zeneca Limited	Acid derivatives
GB9313285D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Acid derivatives
US5780590A (en) *	1993-10-15	1998-07-14	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
WO1995013825A1 (en) *	1993-11-19	1995-05-26	G.D. Searle & Co.	TRANSDERMAL COMPOSITION OF N-[N-[5-[4-(AMINOIMINOMETHYL)PHENYL]-1-OXOPENTYL]-L-α-ASPARTYL]-L-PHENYLALANINE OR ITS ESTERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS
US6387880B1 (en)	1994-10-24	2002-05-14	G.D. Searle & Co.	Transdermal N-[N-[5-[4-(aminoiminomethly)phenyl]-1-oxopentyl]-L-α-aspartyl]-L-phenylalainine or its esters and their pharmaceutically acceptable salts
CN1167485A (zh) *	1994-11-01	1997-12-10	泰尔茂株式会社	四氢异喹啉衍生物和含有它们的药物制剂
US5766932A (en) *	1995-12-20	1998-06-16	Hoechst Marion Roussel, Inc.	Process for preparing N-acetyl(L)-4-cyanophenylalanine from a mixture of the corresponding D,L ethyl esters using subtilisin
NZ324159A (en) *	1995-12-20	1999-07-29	Hoechst Marion Roussel Inc	Process for preparing n-acetyl-(l)-4-cyanophenylalanine ac-(l)-phe(4-cn)-oh and n-acetyl-(l)-p-amidinophenylalanine-cyclohexylglycine-beta-(3-n-methylpyr idinium)-alanine ac-(l)-paph-chg-palme(3)-nh2
JP2001131078A (ja) *	1999-11-09	2001-05-15	Iatron Lab Inc	新規活性固定化血小板及びその製造方法
DE10005631A1 (de) *	2000-02-09	2001-08-23	Max Planck Gesellschaft	Arginin-Mimetika als Faktor X¶a¶-Inhibitoren
PT1317419E (pt) *	2000-09-06	2009-05-08	Emisphere Tech Inc	Compostos e composições de ácido cianofenoxicarboxílico para administrar agentes activos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4857508A (en) *	1987-12-03	1989-08-15	Monsanto Company	Novel platelet-aggregation inhibitor peptide derivatives
US5039805A (en) *	1988-12-08	1991-08-13	Hoffmann-La Roche Inc.	Novel benzoic and phenylacetic acid derivatives
CA2008116C (en) *	1989-02-23	2001-11-20	Thomas Weller	Glycine derivatives
AU646838B2 (en) *	1990-03-09	1994-03-10	F. Hoffmann-La Roche Ag	Acetic acid derivatives
CA2037153A1 (en) *	1990-03-09	1991-09-10	Leo Alig	Acetic acid derivatives
IE920710A1 (en) *	1991-03-06	1992-09-09	Searle & Co	Phenyl amidines derivatives useful as platelet aggregation¹inhibitors
DE4212304A1 (de) *	1992-04-13	1993-10-14	Cassella Ag	Asparaginsäurederivate, ihre Herstellung und Verwendung

1992
- 1992-05-08 AT AT92107757T patent/ATE142641T1/de not_active IP Right Cessation
- 1992-05-08 DE DE69213546T patent/DE69213546T2/de not_active Expired - Fee Related
- 1992-05-08 AU AU16144/92A patent/AU662522B2/en not_active Ceased
- 1992-05-08 EP EP92107757A patent/EP0513675B1/de not_active Expired - Lifetime
- 1992-05-08 DK DK92107757.4T patent/DK0513675T3/da active
- 1992-05-08 ES ES92107757T patent/ES2091359T3/es not_active Expired - Lifetime
- 1992-05-11 TW TW081103635A patent/TW203057B/zh active
- 1992-05-12 CN CN92103241A patent/CN1043647C/zh not_active Expired - Fee Related
- 1992-05-12 HU HU9201578A patent/HUT61780A/hu unknown
- 1992-05-12 JP JP4118870A patent/JP2606528B2/ja not_active Expired - Lifetime
- 1992-05-12 IL IL10183992A patent/IL101839A/en not_active IP Right Cessation
- 1992-05-12 KR KR1019920007969A patent/KR920021579A/ko not_active Application Discontinuation
- 1992-05-12 CA CA002068478A patent/CA2068478A1/en not_active Abandoned
1995
- 1995-05-22 US US08/446,288 patent/US5574016A/en not_active Expired - Fee Related
- 1995-06-22 HU HU95P/P00352P patent/HU211266A9/hu unknown
- 1995-08-18 CN CN95109813A patent/CN1120047A/zh active Pending
1996
- 1996-09-27 GR GR960402534T patent/GR3021182T3/el unknown

Also Published As

Publication number	Publication date
AU662522B2 (en)	1995-09-07
ES2091359T3 (es)	1996-11-01
GR3021182T3 (en)	1996-12-31
EP0513675A1 (de)	1992-11-19
AU1614492A (en)	1992-11-19
CN1043647C (zh)	1999-06-16
CN1120047A (zh)	1996-04-10
IL101839A0 (en)	1992-12-30
HU211266A9 (en)	1995-11-28
TW203057B (de)	1993-04-01
CN1066660A (zh)	1992-12-02
HU9201578D0 (en)	1992-08-28
CA2068478A1 (en)	1992-11-14
JP2606528B2 (ja)	1997-05-07
DE69213546T2 (de)	1997-02-27
IL101839A (en)	1996-12-05
KR920021579A (ko)	1992-12-18
EP0513675B1 (de)	1996-09-11
HUT61780A (en)	1993-03-01
US5574016A (en)	1996-11-12
DE69213546D1 (de)	1996-10-17
JPH05148207A (ja)	1993-06-15
ATE142641T1 (de)	1996-09-15

Publication	Publication Date	Title
DK0513675T3 (da)	1996-09-30	Hidtil ukendt peptidforbindelse samt fremgangsmåde til fremstilling deraf
FI882813A (fi)	1988-12-16	Pyrazolopyridinfoerening och foerfarande foer dess framstaellning.
DK0379979T3 (de)	1997-04-07
DK0622361T3 (da)	2001-12-03	Heterocykliske forbindelser som bradykininantagonister
DK0467248T3 (da)	1999-07-05	Pyrazolopyridinforbindelse og fremgangsmåder til fremstilling heraf
PT976748E (pt)	2004-03-31	Derivados de pirrolidina com actividade inibidora de fosfolipase a2
DE69413237D1 (en)	1998-10-15	Plättchenaggregationsinhibitoren
ES2148254T3 (es)	2000-10-16	Peptidos antimicrobianos ciclicos y preparacion de los mismos.
HU914153D0 (en)	1992-03-30	Electrically operated lock
DK0559079T3 (da)	1998-03-30	Substituerede aminophosphonatderivater, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende derivaterne
CA2140927A1 (en)	1994-03-05	Platelet aggregation inhibitors
DE68926981D1 (de)	1996-09-26	Cephemverbindungen und Verfahren zu ihrer Herstellung
EP0604352A3 (de)	1995-02-08	Arylsubstituierte heterocyclische Verbindungen.
DE69330601D1 (de)	2001-09-20	Serotoninergische ergolin derivate
DE69329184D1 (de)	2000-09-14	Alkylsubstituierte heterocyclische Verbindungen
FI895139A0 (fi)	1989-10-30	Pyrrolidinderivat.
WO1987004435A3 (en)	1988-03-24	Xanthine compounds
ES2149180T3 (es)	2000-11-01	Derivado de pirazolotiazolopirimidina.