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DE69936911D1 - Propofolhaltiges arzneimittel enthaltend sulfite - Google Patents

Propofolhaltiges arzneimittel enthaltend sulfite

Info

Publication number
DE69936911D1
DE69936911D1 DE69936911T DE69936911T DE69936911D1 DE 69936911 D1 DE69936911 D1 DE 69936911D1 DE 69936911 T DE69936911 T DE 69936911T DE 69936911 T DE69936911 T DE 69936911T DE 69936911 D1 DE69936911 D1 DE 69936911D1
Authority
DE
Germany
Prior art keywords
propol
sulphite
medicament
medicament containing
containing medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69936911T
Other languages
English (en)
Other versions
DE69936911T2 (de
Inventor
Dorla Mirejovsky
Liananingsih Tanudarma
Dilip Ashtekar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sicor Inc
Original Assignee
Sicor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicor Inc filed Critical Sicor Inc
Application granted granted Critical
Publication of DE69936911D1 publication Critical patent/DE69936911D1/de
Publication of DE69936911T2 publication Critical patent/DE69936911T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69936911T 1998-02-10 1999-02-10 Propofolhaltiges arzneimittel enthaltend sulfite Expired - Fee Related DE69936911T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2167198A 1998-02-10 1998-02-10
US21671 1998-02-10
PCT/US1999/003036 WO1999039696A1 (en) 1998-02-10 1999-02-10 Propofol composition containing sulfite

Publications (2)

Publication Number Publication Date
DE69936911D1 true DE69936911D1 (de) 2007-10-04
DE69936911T2 DE69936911T2 (de) 2008-05-15

Family

ID=21805509

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69936911T Expired - Fee Related DE69936911T2 (de) 1998-02-10 1999-02-10 Propofolhaltiges arzneimittel enthaltend sulfite

Country Status (17)

Country Link
US (2) US6147122A (de)
EP (1) EP1052975B1 (de)
JP (1) JP2002502811A (de)
AR (1) AR015516A1 (de)
AT (1) ATE370726T1 (de)
AU (1) AU750040B2 (de)
BR (1) BR9907832A (de)
CA (1) CA2319810C (de)
CO (1) CO4810371A1 (de)
CY (1) CY1106970T1 (de)
DE (1) DE69936911T2 (de)
DK (1) DK1052975T3 (de)
ES (1) ES2292233T3 (de)
NZ (1) NZ505948A (de)
PE (1) PE20000264A1 (de)
PT (1) PT1052975E (de)
WO (1) WO1999039696A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6749868B1 (en) 1993-02-22 2004-06-15 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
KR100777647B1 (ko) 1998-08-19 2007-11-19 스키에파마 캐나다 인코포레이티드 프로포폴의 수용성 주사용 분산액
IL153457A0 (en) 2000-06-16 2003-07-06 Skyepharma Canada Inc Improved injectable dispersions of propofol
IN188917B (de) * 2000-12-07 2002-11-23 Bharat Surums & Vaccines Ltd
DE60117467T2 (de) * 2000-12-22 2006-09-28 Astellas Pharma Inc. Famotidin-injektionen
JP4127757B2 (ja) * 2001-08-21 2008-07-30 株式会社エヌ・ティ・ティ・ドコモ 無線通信システム、通信端末装置、及びバースト信号送信方法
NZ534012A (en) * 2002-01-25 2006-12-22 Theravance Inc Substituted phenylacetic acid ester compounds as short-acting sedative hypnotic agents for anesthesia and sedation
RU2297216C2 (ru) * 2002-04-08 2007-04-20 Эм-Джи-Ай Джи-Пи,Инк. Фармацевтические композиции, содержащие растворимые в воде пролекарства пропофола, и способы их применения
JP4290381B2 (ja) * 2002-04-11 2009-07-01 学校法人 聖マリアンナ医科大学 ピリドンカルボン酸化合物含有エマルション
AU2003286725B2 (en) * 2002-10-29 2007-07-12 Transform Pharmaceuticals, Inc. Propofol with cysteine
US20050004002A1 (en) 2002-12-09 2005-01-06 American Bioscience, Inc. Compositions and methods of delivery of pharmacological agents
US20040225022A1 (en) * 2003-05-09 2004-11-11 Desai Neil P. Propofol formulation containing reduced oil and surfactants
US8476010B2 (en) 2003-07-10 2013-07-02 App Pharmaceuticals Llc Propofol formulations with non-reactive container closures
SI1648413T1 (sl) * 2003-07-23 2010-01-29 Theravance Inc Farmacevtski sestavki kratko delujočega sedativnega hipnotičnega sredstva
US8546453B2 (en) * 2003-08-14 2013-10-01 Rensheng Zhang Propofol compositions and methods for reducing pain associated with propofol injection
US20070213411A1 (en) * 2003-11-05 2007-09-13 The Australian National University Dispersions And Methods Of Preparing Them
WO2005077337A2 (en) * 2004-02-05 2005-08-25 Baxter International Inc. Dispersions prepared by use of self-stabilizing agents
NZ549016A (en) 2004-02-13 2012-03-30 Bioavailability Inc A microemulsion preparation of high concentration propofol for anesthetic uses
BRPI0515181A (pt) * 2004-09-13 2008-07-22 Bharat Serums & Vaccines Ltd composição de óleo-em-água estéril para administração intravenosa, uso de um monoglicerìdeo e processo de preparação de uma composição para administração intravenosa
US8557861B2 (en) * 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
US20070293586A1 (en) * 2005-02-03 2007-12-20 Suresh Dixit Novel propofol composition comprising ascorbic acid or pharmaceutically acceptable salts thereof
CN100358513C (zh) * 2005-04-07 2008-01-02 常州市第四制药厂有限公司 一种丙泊酚注射液的制备工艺
WO2006128088A1 (en) * 2005-05-27 2006-11-30 Sandhya Goyal Novel propofol composition comprising a pharmaceutically acceptable salt of formaldehyde sulfoxylate
JP2009503059A (ja) 2005-08-05 2009-01-29 ブハラット セルムズ アンド ヴァクシンズ リミテッド 防腐効果を有する静脈プロポフォールエマルジョン組成物
CN101287447B (zh) * 2005-08-12 2012-10-24 印度血清及疫苗有限公司 包含丙泊酚的水性麻醉剂组合物
WO2007027941A2 (en) 2005-08-31 2007-03-08 Abraxis Bioscience, Llc. Compositions and methods for preparation of poorly water soluble drugs with increased stability
EP1931321B1 (de) 2005-08-31 2018-12-26 Abraxis BioScience, LLC Zusammensetzungen aus schwer wasserlöslichen pharmazeutischen mitteln und antimikrobiellen mitteln
US20070092464A1 (en) * 2005-10-25 2007-04-26 Duff Rocky J Betadine neutralizer
TWI376239B (en) * 2006-02-01 2012-11-11 Andrew Xian Chen Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
US9132090B2 (en) 2009-01-13 2015-09-15 Chetan Majmudar Propofol based anesthetic with preservative
EP2627173B2 (de) * 2010-10-12 2018-07-04 Chiesi Farmaceutici S.p.A. Clevidipin-emulsionsformulierungen mit antimikrobiellen mitteln
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
WO2013172999A1 (en) 2012-05-16 2013-11-21 Mewa Singh Pharmaceutical compositions for the delivery of substantially water-insoluble drugs
CN104622806B (zh) * 2015-02-04 2018-03-16 北京蓝丹医药科技有限公司 一种丙泮尼地药物组合物及其制备方法
US10821087B2 (en) 2015-07-24 2020-11-03 Neon Laboratories Limited Stabilized injectable emulsion of Propofol and Ketamine
WO2017031261A1 (en) 2015-08-20 2017-02-23 Mewa Singh Polyphenolic polymer to make water-insoluble molecules become water-soluble
US11992483B2 (en) 2021-03-31 2024-05-28 Cali Biosciences Us, Llc Emulsions for local anesthetics

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472793A (en) * 1974-03-28 1977-05-04 Ici Ltd Pharmaceutical compositions
US4798846A (en) * 1974-03-28 1989-01-17 Imperial Chemical Industries Plc Pharmaceutical compositions
ATE173251T1 (de) * 1991-08-21 1998-11-15 Eisai Co Ltd Kondensierte pyrimidinderivate als antitumorverbindungen
US5731356A (en) * 1994-03-22 1998-03-24 Zeneca Limited Pharmaceutical compositions of propofol and edetate
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
WO1997010814A1 (en) * 1995-09-18 1997-03-27 Vesifact Ag Propofol nanodispersions
US5637625A (en) * 1996-03-19 1997-06-10 Research Triangle Pharmaceuticals Ltd. Propofol microdroplet formulations

Also Published As

Publication number Publication date
AU750040B2 (en) 2002-07-11
PT1052975E (pt) 2007-10-29
BR9907832A (pt) 2000-10-31
EP1052975B1 (de) 2007-08-22
DE69936911T2 (de) 2008-05-15
ES2292233T3 (es) 2008-03-01
WO1999039696A1 (en) 1999-08-12
DK1052975T3 (da) 2007-12-27
CA2319810A1 (en) 1999-08-12
CA2319810C (en) 2008-12-23
US6147122A (en) 2000-11-14
AR015516A1 (es) 2001-05-02
ATE370726T1 (de) 2007-09-15
CO4810371A1 (es) 1999-06-30
US6469069B1 (en) 2002-10-22
NZ505948A (en) 2003-10-31
AU2599199A (en) 1999-08-23
CY1106970T1 (el) 2012-09-26
JP2002502811A (ja) 2002-01-29
PE20000264A1 (es) 2000-04-11
EP1052975A1 (de) 2000-11-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee