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DE69933388D1 - Pharmazeutische Lösungen VON TRIPHENYLETHYLEN-ANTIÖSTROGENEN - Google Patents

Pharmazeutische Lösungen VON TRIPHENYLETHYLEN-ANTIÖSTROGENEN

Info

Publication number
DE69933388D1
DE69933388D1 DE69933388T DE69933388T DE69933388D1 DE 69933388 D1 DE69933388 D1 DE 69933388D1 DE 69933388 T DE69933388 T DE 69933388T DE 69933388 T DE69933388 T DE 69933388T DE 69933388 D1 DE69933388 D1 DE 69933388D1
Authority
DE
Germany
Prior art keywords
triphenylethylene
antiotrogenes
corresponding anion
pharmaceutical solutions
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69933388T
Other languages
English (en)
Other versions
DE69933388T2 (de
Inventor
Juha Kiesvaara
Gunilla Oern
Mikko Kananen
Pirjo Kortesuo
Heikki Niskanen
Jukka Salmia
Ursin Kaija Af
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Oyj filed Critical Orion Oyj
Application granted granted Critical
Publication of DE69933388D1 publication Critical patent/DE69933388D1/de
Publication of DE69933388T2 publication Critical patent/DE69933388T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Dental Preparations (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
DE69933388T 1998-12-17 1999-12-16 Pharmazeutische Lösungen VON TRIPHENYLETHYLEN-ANTIÖSTROGENEN Expired - Lifetime DE69933388T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI982733 1998-12-17
FI982733A FI982733L (fi) 1998-12-17 1998-12-17 Trifenyylietyleeniantiestrogeenien liukoisia koostumuksia
PCT/FI1999/001046 WO2000035485A1 (en) 1998-12-17 1999-12-16 Soluble compositions of triphenylethylene antiestrogens

Publications (2)

Publication Number Publication Date
DE69933388D1 true DE69933388D1 (de) 2006-11-09
DE69933388T2 DE69933388T2 (de) 2007-08-23

Family

ID=8553138

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933388T Expired - Lifetime DE69933388T2 (de) 1998-12-17 1999-12-16 Pharmazeutische Lösungen VON TRIPHENYLETHYLEN-ANTIÖSTROGENEN

Country Status (13)

Country Link
US (2) US6632841B1 (de)
EP (1) EP1140196B1 (de)
JP (1) JP4523167B2 (de)
AT (1) ATE340591T1 (de)
AU (1) AU767714B2 (de)
CA (1) CA2355175C (de)
DE (1) DE69933388T2 (de)
ES (1) ES2272092T3 (de)
FI (1) FI982733L (de)
IL (2) IL143575A0 (de)
NO (1) NO330251B1 (de)
NZ (1) NZ512270A (de)
WO (1) WO2000035485A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI982733L (fi) * 1998-12-17 2000-06-18 Orion Yhtymae Oyj Trifenyylietyleeniantiestrogeenien liukoisia koostumuksia
EP1832582A1 (de) * 2002-09-30 2007-09-12 A/S GEA Farmaceutisk Fabrik Neue Malonsäureadditionssalze aus Raloxifen und/oder Solvate daraus sowie pharmazeutische Zusammensetzungen damit
US7968532B2 (en) * 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
US7507769B2 (en) * 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP2373305B1 (de) * 2008-12-11 2017-03-15 Besins Healthcare Luxembourg SARL Ein serm enthaltende transdermale pharmazeutische zusammensetzungen
JP6356678B2 (ja) * 2012-09-17 2018-07-11 ファイザー・インク 治療用ナノ粒子を製造する方法
ME02860B (de) 2013-09-16 2018-04-20 Astrazeneca Ab Therapeutische polymernanopartikel sowie verfahren zur herstellung und verwendung davon
EP3015453B1 (de) * 2014-10-28 2016-10-12 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Verfahren zur Herstellung von Clomiphen
CN108463453A (zh) 2016-04-22 2018-08-28 意大利合成制造有限公司 用于制备具有针状晶体习性的柠檬酸恩氯米芬的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE293263C (de)
FR2558373B1 (fr) 1984-01-20 1987-07-03 Mauvais Jarvis Pierre Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee
GB8604528D0 (en) 1986-02-24 1986-04-03 Ici Plc Therapeutic agents
EP0396069B1 (de) 1989-05-05 1994-06-22 ASTA Medica Aktiengesellschaft Salze des Azelastins mit verbesserter Löslichkeit
US5189212A (en) * 1990-09-07 1993-02-23 University Of Georgia Research Foundation, Inc. Triarylethylene carboxylic acids with estrogenic activity
GB9126209D0 (en) 1991-12-10 1992-02-12 Orion Yhtymae Oy Drug formulations for parenteral use
GB9207437D0 (en) 1992-04-03 1992-05-20 Orion Yhtymae Oy Topical administration of toremifene and its metabolites
IT1263831B (it) 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina
DE4407742C1 (de) 1994-03-08 1995-06-22 Hexal Pharma Gmbh Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat
US5441986A (en) * 1994-07-19 1995-08-15 Pfizer Inc. Estrogen agonists as remedies for prostate and cardiovascular diseases
HUP0001172A3 (en) * 1996-08-28 2002-01-28 Lilly Co Eli Amorphous benzothiophenes, methods of preparation, and methods of use
CA2219377A1 (en) 1996-10-30 1998-04-30 Eli Lilly And Company Improvements in or relating to the prophylaxis of breast cancer
US6114395A (en) 1996-11-15 2000-09-05 Pfizer Inc. Method of treating atherosclerosis
EP0893121B1 (de) 1997-06-27 2002-03-13 Akzo Nobel N.V. Oral anzuwendende flüssige Arzneilösung
WO1999024032A1 (en) 1997-11-10 1999-05-20 Novo Nordisk A/S Transdermal delivery of 3,4-diarylchromans
FI109332B (fi) * 1998-12-17 2002-07-15 Orion Yhtymae Oyj Toremifeenin liukoisia koostumuksia
FI982733L (fi) * 1998-12-17 2000-06-18 Orion Yhtymae Oyj Trifenyylietyleeniantiestrogeenien liukoisia koostumuksia

Also Published As

Publication number Publication date
FI982733A7 (fi) 2000-06-18
NO20012793D0 (no) 2001-06-06
ATE340591T1 (de) 2006-10-15
DE69933388T2 (de) 2007-08-23
EP1140196B1 (de) 2006-09-27
FI982733L (fi) 2000-06-18
CA2355175C (en) 2008-07-15
JP2002532437A (ja) 2002-10-02
US6887888B2 (en) 2005-05-03
AU1985500A (en) 2000-07-03
EP1140196A1 (de) 2001-10-10
WO2000035485A1 (en) 2000-06-22
US20030181530A1 (en) 2003-09-25
NO20012793L (no) 2001-08-09
FI982733A0 (fi) 1998-12-17
JP4523167B2 (ja) 2010-08-11
IL143575A (en) 2006-12-10
CA2355175A1 (en) 2000-06-22
NZ512270A (en) 2003-01-31
AU767714B2 (en) 2003-11-20
US6632841B1 (en) 2003-10-14
IL143575A0 (en) 2002-04-21
NO330251B1 (no) 2011-03-14
ES2272092T3 (es) 2007-04-16

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Legal Events

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