DE69903252D1 - Verfahren zur Herstellung der Taxolanalogen 10-Deacetyltaxol A, B und C - Google Patents
Verfahren zur Herstellung der Taxolanalogen 10-Deacetyltaxol A, B und CInfo
- Publication number
- DE69903252D1 DE69903252D1 DE69903252T DE69903252T DE69903252D1 DE 69903252 D1 DE69903252 D1 DE 69903252D1 DE 69903252 T DE69903252 T DE 69903252T DE 69903252 T DE69903252 T DE 69903252T DE 69903252 D1 DE69903252 D1 DE 69903252D1
- Authority
- DE
- Germany
- Prior art keywords
- deacetyltaxol
- preparation
- taxol analogs
- taxol
- analogs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- TYLVGQKNNUHXIP-MHHARFCSSA-N 10-Deacetyltaxol A Natural products O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)C=4C=CC=CC=4)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 TYLVGQKNNUHXIP-MHHARFCSSA-N 0.000 title 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical class O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN231DE1999 IN192059B (de) | 1999-02-12 | 1999-02-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69903252D1 true DE69903252D1 (de) | 2002-11-07 |
| DE69903252T2 DE69903252T2 (de) | 2003-02-13 |
Family
ID=11088821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69903252T Expired - Lifetime DE69903252T2 (de) | 1999-02-12 | 1999-03-12 | Verfahren zur Herstellung der Taxolanalogen 10-Deacetyltaxol A, B und C |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US6028206A (de) |
| EP (1) | EP1028116B1 (de) |
| DE (1) | DE69903252T2 (de) |
| IN (1) | IN192059B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6624317B1 (en) | 2000-09-25 | 2003-09-23 | The University Of North Carolina At Chapel Hill | Taxoid conjugates as antimitotic and antitumor agents |
| DE60109165T2 (de) * | 2001-09-28 | 2006-02-16 | Council Of Scientific And Industrial Research | Verfahren zur Herstellung von 10-Desacetylbaccatin III |
| US6437154B1 (en) | 2001-09-28 | 2002-08-20 | Council Of Scientific And Industrial Research | Process for the preparation of 10-deacetylbaccatin III |
| JP3632059B2 (ja) * | 2002-07-31 | 2005-03-23 | 伊東電機株式会社 | 直流ブラシレスモータ制御装置 |
| US7605278B2 (en) * | 2002-08-04 | 2009-10-20 | Natural Pharmaceuticals, Inc. | Methods and compositions for converting taxane amides to paclitaxel or other taxanes |
| US20080220074A1 (en) * | 2002-10-04 | 2008-09-11 | Elan Corporation Plc | Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same |
| CN102296053B (zh) | 2010-06-25 | 2015-03-11 | 中国医学科学院药物研究所 | 一种7-木糖紫杉烷糖基水解酶、其基因的核苷酸序列及其应用 |
| CN111662252A (zh) * | 2020-07-08 | 2020-09-15 | 云南汉德生物技术有限公司 | 一种利用废料制备10-脱乙酰基巴卡亭ⅲ的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601676B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
| US5380916A (en) * | 1990-11-02 | 1995-01-10 | University Of Florida | Method for the isolation and purification of taxane derivatives |
| US5200534A (en) * | 1992-03-13 | 1993-04-06 | University Of Florida | Process for the preparation of taxol and 10-deacetyltaxol |
| US5856532A (en) * | 1996-08-14 | 1999-01-05 | Council Of Scientific & Industrial Research | Process for the production of taxol |
-
1999
- 1999-02-12 IN IN231DE1999 patent/IN192059B/en unknown
- 1999-03-05 US US09/264,383 patent/US6028206A/en not_active Expired - Lifetime
- 1999-03-12 EP EP99301915A patent/EP1028116B1/de not_active Expired - Lifetime
- 1999-03-12 DE DE69903252T patent/DE69903252T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1028116B1 (de) | 2002-10-02 |
| DE69903252T2 (de) | 2003-02-13 |
| US6028206A (en) | 2000-02-22 |
| EP1028116A1 (de) | 2000-08-16 |
| IN192059B (de) | 2004-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| R082 | Change of representative |
Ref document number: 1028116 Country of ref document: EP Representative=s name: BOEHMERT & BOEHMERT, DE |