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DE69840526D1 - Verwendung von inhaliertem stickstoffmonoxid als entzündungshemmendes agens - Google Patents

Verwendung von inhaliertem stickstoffmonoxid als entzündungshemmendes agens

Info

Publication number
DE69840526D1
DE69840526D1 DE69840526T DE69840526T DE69840526D1 DE 69840526 D1 DE69840526 D1 DE 69840526D1 DE 69840526 T DE69840526 T DE 69840526T DE 69840526 T DE69840526 T DE 69840526T DE 69840526 D1 DE69840526 D1 DE 69840526D1
Authority
DE
Germany
Prior art keywords
inflammatory agent
nitrogen monoxide
inhaled nitrogen
inhaled
monoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840526T
Other languages
English (en)
Inventor
Warren M Zapol
Kenneth D Bloch
Anthony Rosenzweig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26742873&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69840526(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of DE69840526D1 publication Critical patent/DE69840526D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
DE69840526T 1997-10-21 1998-10-19 Verwendung von inhaliertem stickstoffmonoxid als entzündungshemmendes agens Expired - Lifetime DE69840526D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6292697P 1997-10-21 1997-10-21
US08/971,003 US6656452B1 (en) 1997-10-21 1997-11-14 Use of inhaled NO as anti-inflammatory agent
PCT/US1998/022044 WO1999020251A1 (en) 1997-10-21 1998-10-19 Use of inhaled no as anti-inflammatory agent

Publications (1)

Publication Number Publication Date
DE69840526D1 true DE69840526D1 (de) 2009-03-19

Family

ID=26742873

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69840526T Expired - Lifetime DE69840526D1 (de) 1997-10-21 1998-10-19 Verwendung von inhaliertem stickstoffmonoxid als entzündungshemmendes agens

Country Status (13)

Country Link
US (2) US6656452B1 (de)
EP (1) EP1073416B1 (de)
JP (1) JP2003532615A (de)
AR (1) AR015973A1 (de)
AT (1) ATE421874T1 (de)
AU (1) AU751853B2 (de)
CA (1) CA2309038C (de)
CY (1) CY1110228T1 (de)
DE (1) DE69840526D1 (de)
DK (1) DK1073416T3 (de)
ES (1) ES2319240T3 (de)
PT (1) PT1073416E (de)
WO (1) WO1999020251A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19834506A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Transmucosales therapeutisches System zur Anwendung von Sildenafil
US20030070674A1 (en) * 2001-10-12 2003-04-17 Bryan Perry Use of aerosolized compounds in the treatment of exercise induced pulmonary hemorrhage in an equine
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
US7086397B2 (en) * 2002-02-16 2006-08-08 Graham Lindley Spruiell Patient usable emergency medical kit
US7091207B2 (en) * 2002-05-22 2006-08-15 Virginia Commonwealth University Method of treating myocardial infarction with PDE-5 inhibitors
US20050244508A1 (en) * 2002-06-12 2005-11-03 Messer Griesheim Anti-spasmodic comprising xenon
HRP20041204A2 (en) * 2002-06-21 2005-06-30 University Of Pittsburgh Of The Commonwealth Systebeth Israel Deaconess Medical Center Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
ES2294543T3 (es) 2003-07-09 2008-04-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Heal Uso de sales de nitrilo para el tratamiento de afecciones cardiovasculares.
US20050255178A1 (en) * 2004-02-04 2005-11-17 Bloch Kenneth D Enhancing the effectiveness of an inhaled therapeutic gas
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US8557300B2 (en) * 2005-05-19 2013-10-15 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
WO2007130725A2 (en) * 2006-02-06 2007-11-15 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of hmgb1 for protection against ischemia reperfusion injury
KR20090087900A (ko) * 2006-11-07 2009-08-18 더 제너럴 하스피탈 코포레이션 혈관작용성 산소운반체에 의해 유도되는 혈관수축의 감소
WO2008132239A1 (en) 2007-04-30 2008-11-06 Nnoxe Pharmaceutiques Inc Pharmaceutical composition comprising at least one thrombolytic agent (a) and at least one gas (b) selected from the group consisting of nitrous oxide, argon, xenon, helium, neon
WO2010049423A1 (en) * 2008-10-27 2010-05-06 Life Sciences Research Partners Vzw Effects of nitric oxide inhalation on long-term myocardial reperfusion injury
AR077041A1 (es) 2009-06-09 2011-07-27 Prolong Pharmaceuticals Inc Composiciones de hemoglobina. metodos.
JP5581500B2 (ja) * 2010-03-10 2014-09-03 学校法人北里研究所 虚血再灌流障害軽減用治療剤および治療装置
JP2014506872A (ja) * 2010-12-03 2014-03-20 ゲノ エルエルシー 一酸化窒素治療
US9573110B2 (en) 2011-10-03 2017-02-21 NitricGen, Inc. Apparatus and method for generating nitric oxide in controlled and accurate amounts
HK1200355A1 (en) 2011-11-07 2015-08-07 通用医疗公司 Treatment of red blood cells
JP2014141536A (ja) * 2014-05-16 2014-08-07 Kitasato Institute 虚血再灌流障害軽減用治療剤および治療装置
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
WO2023190532A1 (ja) * 2022-03-29 2023-10-05 康太郎 木田 横紋筋融解症を治療するための医薬組成物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5396882A (en) 1992-03-11 1995-03-14 The General Hospital Corporation Generation of nitric oxide from air for medical uses
US5570683A (en) * 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
US5536241A (en) 1990-12-05 1996-07-16 The General Hospital Corporation Methods and devices for relaxing smooth muscle contractions
DK1516639T4 (en) * 1990-12-05 2015-06-29 Gen Hospital Corp Use of NO to treat persistent pulmonary hypertension in newborns
US5427797A (en) 1993-04-06 1995-06-27 Brigham And Women's Hospital Systemic effects of nitric oxide inhalation
GB9320978D0 (en) 1993-10-12 1993-12-01 Higenbottam Timohy W Nitric oxide treatment
PT726768E (pt) 1993-11-02 2000-11-30 Us Health Utilizacao de compostos libertadores de acido nitrico para o fabrico de um medicamento para proteccao na lesao por isquemia-reperfusao
US5521191A (en) 1994-10-17 1996-05-28 Washington University Method for treatment of arterial stenosis
US6063407A (en) 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US5823180A (en) 1995-04-03 1998-10-20 The General Hospital Corporation Methods for treating pulmonary vasoconstriction and asthma
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US5725492A (en) * 1996-03-04 1998-03-10 Cormedics Corp Extracorporeal circulation apparatus and method
ES2267141T3 (es) 1996-04-05 2007-03-01 The General Hospital Corporation Tratamiento de una hemoglobinopatia.
US6601580B1 (en) 2000-06-28 2003-08-05 The General Hospital Corporation Enhancing therapeutic effectiveness of nitric oxide inhalation

Also Published As

Publication number Publication date
CA2309038C (en) 2009-04-21
ATE421874T1 (de) 2009-02-15
ES2319240T3 (es) 2009-05-05
EP1073416A1 (de) 2001-02-07
WO1999020251A1 (en) 1999-04-29
JP2003532615A (ja) 2003-11-05
DK1073416T3 (da) 2009-03-09
EP1073416A4 (de) 2004-07-07
EP1073416B1 (de) 2009-01-28
US20040096523A1 (en) 2004-05-20
AU1101299A (en) 1999-05-10
AR015973A1 (es) 2001-05-30
US6811768B2 (en) 2004-11-02
CY1110228T1 (el) 2015-01-14
PT1073416E (pt) 2009-03-17
CA2309038A1 (en) 1999-04-29
AU751853B2 (en) 2002-08-29
US6656452B1 (en) 2003-12-02

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Legal Events

Date Code Title Description
8363 Opposition against the patent