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DE69510228D1 - Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel - Google Patents

Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel

Info

Publication number
DE69510228D1
DE69510228D1 DE69510228T DE69510228T DE69510228D1 DE 69510228 D1 DE69510228 D1 DE 69510228D1 DE 69510228 T DE69510228 T DE 69510228T DE 69510228 T DE69510228 T DE 69510228T DE 69510228 D1 DE69510228 D1 DE 69510228D1
Authority
DE
Germany
Prior art keywords
piperidinessigic
fibrinogenic
acid derivatives
antagonist agents
antagonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69510228T
Other languages
English (en)
Other versions
DE69510228T2 (de
Inventor
David Allen
Colin Eldred
William Mitchell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9426231.8A external-priority patent/GB9426231D0/en
Priority claimed from GBGB9503133.2A external-priority patent/GB9503133D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE69510228D1 publication Critical patent/DE69510228D1/de
Application granted granted Critical
Publication of DE69510228T2 publication Critical patent/DE69510228T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69510228T 1994-12-23 1995-12-21 Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel Expired - Fee Related DE69510228T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9426231.8A GB9426231D0 (en) 1994-12-23 1994-12-23 Chemical compounds
GBGB9503133.2A GB9503133D0 (en) 1995-02-17 1995-02-17 Chemical compounds
PCT/EP1995/005043 WO1996020192A1 (en) 1994-12-23 1995-12-21 Piperidineacetic acid derivatives useful as fibrinogen antagonist agent

Publications (2)

Publication Number Publication Date
DE69510228D1 true DE69510228D1 (de) 1999-07-15
DE69510228T2 DE69510228T2 (de) 1999-11-04

Family

ID=26306268

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69510228T Expired - Fee Related DE69510228T2 (de) 1994-12-23 1995-12-21 Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel

Country Status (21)

Country Link
US (1) US5861414A (de)
EP (1) EP0799223B1 (de)
JP (1) JPH10511375A (de)
CN (1) CN1175254A (de)
AP (1) AP9701010A0 (de)
AR (1) AR002260A1 (de)
AT (1) ATE181071T1 (de)
AU (1) AU704496B2 (de)
CO (1) CO4700291A1 (de)
DE (1) DE69510228T2 (de)
DK (1) DK0799223T3 (de)
ES (1) ES2132761T3 (de)
FI (1) FI972684L (de)
GR (1) GR3031027T3 (de)
IL (1) IL116480A0 (de)
NO (1) NO972887L (de)
NZ (1) NZ298400A (de)
PE (1) PE63696A1 (de)
SI (1) SI0799223T1 (de)
WO (1) WO1996020192A1 (de)
ZA (1) ZA951822B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760028A (en) * 1995-12-22 1998-06-02 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists
GB9613096D0 (en) * 1996-06-21 1996-08-28 Glaxo Group Ltd Medicaments
ATE431347T1 (de) 1996-10-14 2009-05-15 Bayer Healthcare Ag Neue heterocyclylmethyl-substituierte pyrazolderivate und ihre verwendung in der behandlung von herz-kreislauf-erkrankungen
US6214834B1 (en) 1997-03-28 2001-04-10 Dupont Pharmaceuticals Company Integrin inhibitor prodrugs
TWI262914B (en) 1999-07-02 2006-10-01 Agouron Pharma Compounds and pharmaceutical compositions for inhibiting protein kinases
US7141581B2 (en) * 1999-07-02 2006-11-28 Agouron Pharmaceuticals, Inc. Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
PE20010306A1 (es) * 1999-07-02 2001-03-29 Agouron Pharma Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
EA200300717A1 (ru) * 2000-12-22 2003-12-25 Уайт Гетероциклилиндазольные и -азаиндазольные соединения в качестве 5-гидрокситриптамин-6-лигандов
US7008953B2 (en) 2003-07-30 2006-03-07 Agouron Pharmaceuticals, Inc. 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
GB0400895D0 (en) * 2004-01-15 2004-02-18 Smithkline Beecham Corp Chemical compounds
TW200616967A (en) * 2004-06-24 2006-06-01 Smithkline Beecham Corp Novel indazole carboxamides and their use
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681382A (en) * 1969-02-07 1972-08-01 Ciba Geigy Corp 3-aminoindazoles
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
US5219867A (en) * 1991-12-16 1993-06-15 Research Corporation Technologies, Inc. Platelet aggregation inhibitory agents
JPH05255308A (ja) * 1992-03-11 1993-10-05 Ajinomoto Co Inc ピペリジン誘導体
JP3194777B2 (ja) * 1992-03-13 2001-08-06 学校法人東京薬科大学 立体選択的ｄ−リボフラノシル化法
JPH06234633A (ja) * 1993-02-10 1994-08-23 Ajinomoto Co Inc アミン誘導体およびこれを含有する抗血小板剤

Also Published As

Publication number Publication date
NZ298400A (en) 1999-10-28
SI0799223T1 (en) 1999-10-31
ZA951822B (en) 1996-09-26
US5861414A (en) 1999-01-19
NO972887D0 (no) 1997-06-20
DK0799223T3 (da) 1999-12-27
EP0799223B1 (de) 1999-06-09
FI972684A0 (fi) 1997-06-19
WO1996020192A1 (en) 1996-07-04
CN1175254A (zh) 1998-03-04
IL116480A0 (en) 1996-03-31
GR3031027T3 (en) 1999-12-31
CO4700291A1 (es) 1998-12-29
PE63696A1 (es) 1997-01-11
AU704496B2 (en) 1999-04-22
AP9701010A0 (en) 1997-07-31
AU4387896A (en) 1996-07-19
DE69510228T2 (de) 1999-11-04
ES2132761T3 (es) 1999-08-16
NO972887L (no) 1997-08-20
AR002260A1 (es) 1998-03-11
JPH10511375A (ja) 1998-11-04
ATE181071T1 (de) 1999-06-15
FI972684L (fi) 1997-06-19
EP0799223A1 (de) 1997-10-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee