DE69837607D1 - Verfahren zum herstellen von dicarbonsäuren - Google Patents
Verfahren zum herstellen von dicarbonsäurenInfo
- Publication number
- DE69837607D1 DE69837607D1 DE69837607T DE69837607T DE69837607D1 DE 69837607 D1 DE69837607 D1 DE 69837607D1 DE 69837607 T DE69837607 T DE 69837607T DE 69837607 T DE69837607 T DE 69837607T DE 69837607 D1 DE69837607 D1 DE 69837607D1
- Authority
- DE
- Germany
- Prior art keywords
- organism
- carbon source
- maintain
- medium
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001991 dicarboxylic acids Chemical class 0.000 title 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 6
- 229910052799 carbon Inorganic materials 0.000 abstract 6
- 239000002028 Biomass Substances 0.000 abstract 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 2
- 150000001735 carboxylic acids Chemical class 0.000 abstract 2
- 230000004060 metabolic process Effects 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US792655 | 1997-01-31 | ||
US08/792,655 US5869301A (en) | 1995-11-02 | 1997-01-31 | Method for the production of dicarboxylic acids |
PCT/US1998/001877 WO1998033930A1 (en) | 1997-01-31 | 1998-01-30 | A method for the production of dicarboxylic acids |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69837607D1 true DE69837607D1 (de) | 2007-05-31 |
DE69837607T2 DE69837607T2 (de) | 2007-12-27 |
Family
ID=25157624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69837607T Expired - Lifetime DE69837607T2 (de) | 1997-01-31 | 1998-01-30 | Verfahren zum herstellen von dicarbonsäuren |
Country Status (14)
Country | Link |
---|---|
US (1) | US5869301A (de) |
EP (1) | EP1012323B1 (de) |
JP (1) | JP3681404B2 (de) |
CN (1) | CN1121500C (de) |
AT (1) | ATE360084T1 (de) |
AU (1) | AU724274B2 (de) |
BR (1) | BR9806822B1 (de) |
CA (1) | CA2278892C (de) |
DE (1) | DE69837607T2 (de) |
DK (1) | DK1012323T3 (de) |
ES (1) | ES2285757T3 (de) |
HU (1) | HU227509B1 (de) |
PT (1) | PT1012323E (de) |
WO (1) | WO1998033930A1 (de) |
Families Citing this family (86)
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AU2003304173A1 (en) | 2002-05-04 | 2005-01-04 | Acorda Therapeutics, Inc. | Compositions and methods for promoting neuronal outgrowth |
DE10220234B4 (de) * | 2002-05-06 | 2013-05-23 | Forschungszentrum Jülich GmbH | Verfahren sowie Mikroorganismen zur mikrobiellen Herstellung von Pyruvat aus Kohlenhydraten sowie Alkoholen |
ES2366333T3 (es) * | 2002-08-15 | 2011-10-19 | Acorda Therapeutics, Inc. | Proteína quimérica. |
ES2373039T3 (es) * | 2003-05-16 | 2012-01-30 | Acorda Therapeutics, Inc. | Composiciones y métodos para el tratamiento de lesiones del cns. |
CA2525784C (en) * | 2003-05-16 | 2019-04-09 | Acorda Therapeutics, Inc. | Proteoglycan degrading mutants for treatment of cns |
US7959914B2 (en) * | 2003-05-16 | 2011-06-14 | Acorda Therapeutics, Inc. | Methods of reducing extravasation of inflammatory cells |
JP4469568B2 (ja) * | 2003-07-09 | 2010-05-26 | 三菱化学株式会社 | 有機酸の製造方法 |
DK1647594T3 (da) * | 2003-07-29 | 2010-05-25 | Res Inst Innovative Tech Earth | Koryneform bakteriel transformant og fremgangsmåde til fremstilling af dicarboxylsyre under anvendelse af denne |
BRPI0413403A (pt) * | 2003-08-28 | 2006-10-17 | Mitsubishi Chem Corp | método para produzir ácido succìnico |
EP1672067B1 (de) * | 2003-09-17 | 2015-11-11 | Mitsubishi Chemical Corporation | Verfahren zur herstellung einer organischen nicht-amino-säure |
WO2005030973A1 (ja) * | 2003-09-30 | 2005-04-07 | Ajinomoto Co., Inc. | 発酵液からのコハク酸の精製方法 |
JP2005295998A (ja) * | 2003-11-07 | 2005-10-27 | Mitsubishi Chemicals Corp | 有機酸アンモニウム溶液の製造方法 |
BRPI0416274A (pt) * | 2003-11-07 | 2007-01-09 | Mitsubishi Chemical Corp E Aji | método para produzir solução de amÈnio de ácido orgánico |
CA2566731C (en) * | 2004-05-18 | 2012-07-24 | Acorda Therapeutics, Inc. | Methods of purifying chondroitinase and stable formulations thereof |
WO2005113744A1 (ja) * | 2004-05-20 | 2005-12-01 | Ajinomoto Co., Inc. | コハク酸生産菌及びコハク酸の製造方法 |
BRPI0510921A (pt) * | 2004-05-20 | 2008-05-20 | Ajinomoto Kk | bactéria produtora de ácido succìnico e processo para produzir ácido succìnico |
WO2006031424A2 (en) | 2004-08-27 | 2006-03-23 | Rice University | Mutant e. coli strain with increased succinic acid production |
WO2006034156A2 (en) * | 2004-09-17 | 2006-03-30 | Rice University | High succinate producing bacteria |
JP4537862B2 (ja) * | 2005-01-18 | 2010-09-08 | 財団法人地球環境産業技術研究機構 | 好気性細菌による高効率な有機酸の製造方法 |
EP2365017B1 (de) | 2005-04-22 | 2019-07-03 | Mitsubishi Chemical Corporation | Aus einer Biomassenressource abgeleitetes Polyester und Herstellungsverfahren dafür |
JP4380654B2 (ja) * | 2005-04-22 | 2009-12-09 | 三菱化学株式会社 | ポリエステル及びその製造方法 |
JP4380653B2 (ja) * | 2005-04-22 | 2009-12-09 | 三菱化学株式会社 | ポリエステル及びその製造方法 |
EP1937821A4 (de) * | 2005-09-09 | 2009-11-11 | Genomatica Inc | Verfahren und organismen zur wachstumsgekoppelten herstellung von succinat |
CA2623635C (en) | 2005-09-26 | 2013-04-02 | Acorda Therapeutics, Inc. | Compositions and methods of using chondroitinase abci mutants |
BRPI0617491B1 (pt) * | 2005-10-18 | 2021-04-27 | Ajinomoto Co., Inc | Processo para produção de ácido succínico |
US7335066B2 (en) * | 2005-12-16 | 2008-02-26 | James A. Carroll | Network connector and connection system |
JP5180060B2 (ja) * | 2006-02-24 | 2013-04-10 | 三菱化学株式会社 | 有機酸生産菌及び有機酸の製造法 |
EP1842843A1 (de) * | 2006-04-04 | 2007-10-10 | Basf Aktiengesellschaft | Verfahren zur Herstellung eines Carbonsäurealkylesters |
UA100673C2 (uk) | 2006-07-21 | 2013-01-25 | Ксилеко, Инк. | Спосіб переробки целюлозної або лігноцелюлозної біомаси (варіанти) |
AU2007307736C1 (en) | 2006-10-10 | 2014-04-10 | Acorda Therapeutics, Inc. | Compositions and methods of using chondroitinase ABCI mutants |
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JP5551448B2 (ja) | 2007-03-16 | 2014-07-16 | ジェノマティカ・インコーポレイテッド | 1,4−ブタンジオールおよびその前駆体の生合成のための組成物および方法 |
BRPI0809400B1 (pt) * | 2007-03-20 | 2018-12-04 | Univ Florida | célula de escherichia coli geneticamente modificada, métodos de cultivo ou crescimento da referida célula e de produção de succinato, fumarato ou malato, e composição contendo a referida célula |
DE102007019184A1 (de) | 2007-04-20 | 2008-10-23 | Organo Balance Gmbh | Mikroorganismus zur Herstellung von Bernsteinsäure |
PT2164975E (pt) | 2007-07-06 | 2012-03-08 | Basf Se | Processo para a produção de uma solução aquosa de glicose |
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EP2220234B1 (de) * | 2007-11-20 | 2012-06-27 | DSM IP Assets B.V. | Dicarbonsäureproduktion in einer rekombinanten hefe |
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JP2011507541A (ja) * | 2007-12-28 | 2011-03-10 | ロケット フレール | 大規模微生物培養法 |
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ES2623932T3 (es) | 2008-07-08 | 2017-07-12 | Dsm Ip Assets B.V. | Producción de ácido succínico por fermentación a bajo pH |
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EP3514242A3 (de) * | 2008-09-10 | 2019-08-28 | Genomatica, Inc. | Mikroorganismen zur herstellung von 1,4-butandiol |
DE102008051727A1 (de) | 2008-10-17 | 2010-04-22 | Organo Balance Gmbh | Mikroorganismus zur Herstellung von Bernsteinsäure |
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FR2941959B1 (fr) * | 2009-02-12 | 2013-06-07 | Roquette Freres | Procedes de production d'acide succinique |
MX337341B (es) | 2009-04-02 | 2016-02-26 | Univ Florida | Diseño de la via para la produccion de succinato. |
KR101774400B1 (ko) * | 2009-04-30 | 2017-09-04 | 게노마티카 인코포레이티드 | 1,3-부탄다이올 생산 유기체 |
KR20120068763A (ko) | 2009-04-30 | 2012-06-27 | 게노마티카 인코포레이티드 | 아이소프로판올, n-부탄올 및 아이소부탄올 생산 유기체 |
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CN110951660B (zh) | 2019-12-19 | 2021-12-03 | 江南大学 | 一株固定co2产苹果酸的大肠杆菌工程菌的构建及应用 |
CN114350718B (zh) * | 2021-12-31 | 2024-06-07 | 安徽丰原发酵技术工程研究有限公司 | 一种发酵生产苹果酸的方法 |
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JPS5543759B2 (de) * | 1972-06-28 | 1980-11-07 | ||
US4190495A (en) * | 1976-09-27 | 1980-02-26 | Research Corporation | Modified microorganisms and method of preparing and using same |
JPS60114197A (ja) * | 1983-11-25 | 1985-06-20 | Agency Of Ind Science & Technol | 微生物によるジカルボン酸の製造法 |
US4871667A (en) * | 1984-11-26 | 1989-10-03 | Agency Of Industrial Science & Technology | Process for preparing muconic acid |
DE3783081T2 (de) * | 1986-06-11 | 1993-04-15 | Michigan Biotech Inst | Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation. |
US5168055A (en) * | 1986-06-11 | 1992-12-01 | Rathin Datta | Fermentation and purification process for succinic acid |
US5143834A (en) * | 1986-06-11 | 1992-09-01 | Glassner David A | Process for the production and purification of succinic acid |
US5182199A (en) * | 1987-05-27 | 1993-01-26 | Hartley Brian S | Thermophilic ethanol production in a two-stage closed system |
AU639237B2 (en) * | 1989-04-27 | 1993-07-22 | Biocontrol Systems, Incorporated | Precipitate test for microorganisms |
US5416020A (en) * | 1992-09-29 | 1995-05-16 | Bio-Technical Resources | Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid |
FR2702492B1 (fr) * | 1993-03-12 | 1995-05-24 | Rhone Poulenc Chimie | Procédé de production par fermentation d'acide itaconique. |
HU213759B (en) * | 1993-06-25 | 1997-09-29 | Du Pont | Process for the preparation of pyruvic acid |
EP0706577B1 (de) * | 1993-07-01 | 1997-08-27 | E.I. Du Pont De Nemours And Company | Verbessertes Verfahren zur Herstellung von Mischuingen aus Glyoxylsäure und Aminoethylphosphonsäure unter Verwendung eines doppelt angereicherten Mikroorganismus |
US5521075A (en) * | 1994-12-19 | 1996-05-28 | Michigan Biotechnology Institute | Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants |
US5504004A (en) * | 1994-12-20 | 1996-04-02 | Michigan Biotechnology Institute | Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms |
-
1997
- 1997-01-31 US US08/792,655 patent/US5869301A/en not_active Expired - Lifetime
-
1998
- 1998-01-30 HU HU0001997A patent/HU227509B1/hu not_active IP Right Cessation
- 1998-01-30 EP EP98903871A patent/EP1012323B1/de not_active Expired - Lifetime
- 1998-01-30 WO PCT/US1998/001877 patent/WO1998033930A1/en active IP Right Grant
- 1998-01-30 ES ES98903871T patent/ES2285757T3/es not_active Expired - Lifetime
- 1998-01-30 CA CA002278892A patent/CA2278892C/en not_active Expired - Fee Related
- 1998-01-30 BR BRPI9806822-9A patent/BR9806822B1/pt not_active IP Right Cessation
- 1998-01-30 DK DK98903871T patent/DK1012323T3/da active
- 1998-01-30 AT AT98903871T patent/ATE360084T1/de active
- 1998-01-30 DE DE69837607T patent/DE69837607T2/de not_active Expired - Lifetime
- 1998-01-30 CN CN98802169A patent/CN1121500C/zh not_active Expired - Fee Related
- 1998-01-30 JP JP53314198A patent/JP3681404B2/ja not_active Expired - Fee Related
- 1998-01-30 AU AU60523/98A patent/AU724274B2/en not_active Ceased
- 1998-01-30 PT PT98903871T patent/PT1012323E/pt unknown
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HUP0001997A2 (hu) | 2000-10-28 |
ATE360084T1 (de) | 2007-05-15 |
HU227509B1 (en) | 2011-07-28 |
BR9806822B1 (pt) | 2009-05-05 |
HUP0001997A3 (en) | 2002-01-28 |
DK1012323T3 (da) | 2007-06-18 |
BR9806822A (pt) | 2000-05-09 |
JP3681404B2 (ja) | 2005-08-10 |
AU6052398A (en) | 1998-08-25 |
CN1121500C (zh) | 2003-09-17 |
WO1998033930A1 (en) | 1998-08-06 |
CA2278892A1 (en) | 1998-08-06 |
ES2285757T3 (es) | 2007-11-16 |
EP1012323B1 (de) | 2007-04-18 |
AU724274B2 (en) | 2000-09-14 |
JP2000515389A (ja) | 2000-11-21 |
EP1012323A4 (de) | 2002-01-16 |
DE69837607T2 (de) | 2007-12-27 |
PT1012323E (pt) | 2007-05-31 |
CN1246155A (zh) | 2000-03-01 |
US5869301A (en) | 1999-02-09 |
CA2278892C (en) | 2009-02-24 |
EP1012323A1 (de) | 2000-06-28 |
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