[go: up one dir, main page]

DE69837607D1 - Verfahren zum herstellen von dicarbonsäuren - Google Patents

Verfahren zum herstellen von dicarbonsäuren

Info

Publication number
DE69837607D1
DE69837607D1 DE69837607T DE69837607T DE69837607D1 DE 69837607 D1 DE69837607 D1 DE 69837607D1 DE 69837607 T DE69837607 T DE 69837607T DE 69837607 T DE69837607 T DE 69837607T DE 69837607 D1 DE69837607 D1 DE 69837607D1
Authority
DE
Germany
Prior art keywords
organism
carbon source
maintain
medium
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837607T
Other languages
English (en)
Other versions
DE69837607T2 (de
Inventor
Nhuan Phu Nghiem
Mark Donnelly
Cynthia S Millard
Lucy Stols
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UT Battelle LLC
UChicago Argonne LLC
Original Assignee
UT Battelle LLC
UChicago Argonne LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UT Battelle LLC, UChicago Argonne LLC filed Critical UT Battelle LLC
Publication of DE69837607D1 publication Critical patent/DE69837607D1/de
Application granted granted Critical
Publication of DE69837607T2 publication Critical patent/DE69837607T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/46Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/853Lactobacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69837607T 1997-01-31 1998-01-30 Verfahren zum herstellen von dicarbonsäuren Expired - Lifetime DE69837607T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US792655 1997-01-31
US08/792,655 US5869301A (en) 1995-11-02 1997-01-31 Method for the production of dicarboxylic acids
PCT/US1998/001877 WO1998033930A1 (en) 1997-01-31 1998-01-30 A method for the production of dicarboxylic acids

Publications (2)

Publication Number Publication Date
DE69837607D1 true DE69837607D1 (de) 2007-05-31
DE69837607T2 DE69837607T2 (de) 2007-12-27

Family

ID=25157624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837607T Expired - Lifetime DE69837607T2 (de) 1997-01-31 1998-01-30 Verfahren zum herstellen von dicarbonsäuren

Country Status (14)

Country Link
US (1) US5869301A (de)
EP (1) EP1012323B1 (de)
JP (1) JP3681404B2 (de)
CN (1) CN1121500C (de)
AT (1) ATE360084T1 (de)
AU (1) AU724274B2 (de)
BR (1) BR9806822B1 (de)
CA (1) CA2278892C (de)
DE (1) DE69837607T2 (de)
DK (1) DK1012323T3 (de)
ES (1) ES2285757T3 (de)
HU (1) HU227509B1 (de)
PT (1) PT1012323E (de)
WO (1) WO1998033930A1 (de)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10129711B4 (de) * 2001-06-22 2007-08-23 Forschungszentrum Jülich GmbH Verfahren zur fermentativen Herstellung von Pyruvat
AU2003304173A1 (en) 2002-05-04 2005-01-04 Acorda Therapeutics, Inc. Compositions and methods for promoting neuronal outgrowth
DE10220234B4 (de) * 2002-05-06 2013-05-23 Forschungszentrum Jülich GmbH Verfahren sowie Mikroorganismen zur mikrobiellen Herstellung von Pyruvat aus Kohlenhydraten sowie Alkoholen
ES2366333T3 (es) * 2002-08-15 2011-10-19 Acorda Therapeutics, Inc. Proteína quimérica.
ES2373039T3 (es) * 2003-05-16 2012-01-30 Acorda Therapeutics, Inc. Composiciones y métodos para el tratamiento de lesiones del cns.
CA2525784C (en) * 2003-05-16 2019-04-09 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of cns
US7959914B2 (en) * 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
JP4469568B2 (ja) * 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
DK1647594T3 (da) * 2003-07-29 2010-05-25 Res Inst Innovative Tech Earth Koryneform bakteriel transformant og fremgangsmåde til fremstilling af dicarboxylsyre under anvendelse af denne
BRPI0413403A (pt) * 2003-08-28 2006-10-17 Mitsubishi Chem Corp método para produzir ácido succìnico
EP1672067B1 (de) * 2003-09-17 2015-11-11 Mitsubishi Chemical Corporation Verfahren zur herstellung einer organischen nicht-amino-säure
WO2005030973A1 (ja) * 2003-09-30 2005-04-07 Ajinomoto Co., Inc. 発酵液からのコハク酸の精製方法
JP2005295998A (ja) * 2003-11-07 2005-10-27 Mitsubishi Chemicals Corp 有機酸アンモニウム溶液の製造方法
BRPI0416274A (pt) * 2003-11-07 2007-01-09 Mitsubishi Chemical Corp E Aji método para produzir solução de amÈnio de ácido orgánico
CA2566731C (en) * 2004-05-18 2012-07-24 Acorda Therapeutics, Inc. Methods of purifying chondroitinase and stable formulations thereof
WO2005113744A1 (ja) * 2004-05-20 2005-12-01 Ajinomoto Co., Inc. コハク酸生産菌及びコハク酸の製造方法
BRPI0510921A (pt) * 2004-05-20 2008-05-20 Ajinomoto Kk bactéria produtora de ácido succìnico e processo para produzir ácido succìnico
WO2006031424A2 (en) 2004-08-27 2006-03-23 Rice University Mutant e. coli strain with increased succinic acid production
WO2006034156A2 (en) * 2004-09-17 2006-03-30 Rice University High succinate producing bacteria
JP4537862B2 (ja) * 2005-01-18 2010-09-08 財団法人地球環境産業技術研究機構 好気性細菌による高効率な有機酸の製造方法
EP2365017B1 (de) 2005-04-22 2019-07-03 Mitsubishi Chemical Corporation Aus einer Biomassenressource abgeleitetes Polyester und Herstellungsverfahren dafür
JP4380654B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
JP4380653B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
EP1937821A4 (de) * 2005-09-09 2009-11-11 Genomatica Inc Verfahren und organismen zur wachstumsgekoppelten herstellung von succinat
CA2623635C (en) 2005-09-26 2013-04-02 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
BRPI0617491B1 (pt) * 2005-10-18 2021-04-27 Ajinomoto Co., Inc Processo para produção de ácido succínico
US7335066B2 (en) * 2005-12-16 2008-02-26 James A. Carroll Network connector and connection system
JP5180060B2 (ja) * 2006-02-24 2013-04-10 三菱化学株式会社 有機酸生産菌及び有機酸の製造法
EP1842843A1 (de) * 2006-04-04 2007-10-10 Basf Aktiengesellschaft Verfahren zur Herstellung eines Carbonsäurealkylesters
UA100673C2 (uk) 2006-07-21 2013-01-25 Ксилеко, Инк. Спосіб переробки целюлозної або лігноцелюлозної біомаси (варіанти)
AU2007307736C1 (en) 2006-10-10 2014-04-10 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase ABCI mutants
WO2008091627A2 (en) * 2007-01-22 2008-07-31 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
JP5551448B2 (ja) 2007-03-16 2014-07-16 ジェノマティカ・インコーポレイテッド 1,4−ブタンジオールおよびその前駆体の生合成のための組成物および方法
BRPI0809400B1 (pt) * 2007-03-20 2018-12-04 Univ Florida célula de escherichia coli geneticamente modificada, métodos de cultivo ou crescimento da referida célula e de produção de succinato, fumarato ou malato, e composição contendo a referida célula
DE102007019184A1 (de) 2007-04-20 2008-10-23 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
PT2164975E (pt) 2007-07-06 2012-03-08 Basf Se Processo para a produção de uma solução aquosa de glicose
WO2009045637A2 (en) 2007-08-10 2009-04-09 Genomatica, Inc. Methods for the synthesis of acrylic acid and derivatives from fumaric acid
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
EP2220234B1 (de) * 2007-11-20 2012-06-27 DSM IP Assets B.V. Dicarbonsäureproduktion in einer rekombinanten hefe
FR2925068B1 (fr) * 2007-12-13 2010-01-08 Roquette Freres Procedes de production d'acide succinique
JP2011507541A (ja) * 2007-12-28 2011-03-10 ロケット フレール 大規模微生物培養法
EP2245137B1 (de) 2008-01-22 2017-08-16 Genomatica, Inc. Verfahren und organismen zur nutzung von synthesegas oder anderen gasförmigen kohlenstoffquellen und methanol
BRPI0909690A2 (pt) 2008-03-05 2019-02-26 Genomatica Inc organismos produtores de alcoóis primários
CA2719679C (en) 2008-03-27 2018-05-01 Genomatica, Inc. Microorganisms for the production of adipic acid and other compounds
JP2011519561A (ja) 2008-05-01 2011-07-14 ジェノマティカ, インコーポレイテッド メタクリル酸の産生のための微生物
US8129154B2 (en) * 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
ES2623932T3 (es) 2008-07-08 2017-07-12 Dsm Ip Assets B.V. Producción de ácido succínico por fermentación a bajo pH
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
EP3514242A3 (de) * 2008-09-10 2019-08-28 Genomatica, Inc. Mikroorganismen zur herstellung von 1,4-butandiol
DE102008051727A1 (de) 2008-10-17 2010-04-22 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
AU2009327490A1 (en) * 2008-12-16 2011-07-28 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
FR2941959B1 (fr) * 2009-02-12 2013-06-07 Roquette Freres Procedes de production d'acide succinique
MX337341B (es) 2009-04-02 2016-02-26 Univ Florida Diseño de la via para la produccion de succinato.
KR101774400B1 (ko) * 2009-04-30 2017-09-04 게노마티카 인코포레이티드 1,3-부탄다이올 생산 유기체
KR20120068763A (ko) 2009-04-30 2012-06-27 게노마티카 인코포레이티드 아이소프로판올, n-부탄올 및 아이소부탄올 생산 유기체
KR20200104931A (ko) 2009-05-07 2020-09-04 게노마티카 인코포레이티드 아디페이트, 헥사메틸렌디아민 및 6-아미노카프로산의 생합성을 위한 미생물 및 방법
KR20120036851A (ko) * 2009-05-15 2012-04-18 게노마티카 인코포레이티드 사이클로헥사논의 제조를 위한 유기체
KR20180042467A (ko) * 2009-06-04 2018-04-25 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
EP3392340B1 (de) 2009-06-04 2022-01-05 Genomatica, Inc. Mikroorganismen zur herstellung von 1,4-butandiol und entsprechende verfahren
WO2010144746A2 (en) * 2009-06-10 2010-12-16 Genomatica, Inc. Microorganisms and methods for carbon-efficient biosynthesis of mek and 2-butanol
DK2462221T3 (en) 2009-08-05 2017-05-22 Genomatica Inc SEMISYNTHETIC TEREPHTHALIC ACID BY MICRO-ORGANISMS PRODUCING MUCONIC ACID
EP2470667B1 (de) * 2009-08-27 2017-11-15 DSM IP Assets B.V. Fermentationsverfahren zur Herstellung von Dicarbonsäuren
CA2773694A1 (en) 2009-09-09 2011-03-17 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids
MX2012004291A (es) 2009-10-13 2012-08-17 Genomatica Inc Microorganismos para la produccion de 1,4-butanoidol, 4-hidroxibutanal, 4-hidroxibutiril-coa, putrescina y compuestos y metodos relacionados con los mismos.
KR20120088753A (ko) 2009-10-23 2012-08-08 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
CN102753698A (zh) 2009-12-10 2012-10-24 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
AU2011209862A1 (en) 2010-01-29 2012-07-26 Genomatica, Inc. Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
US8445244B2 (en) * 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
BR112012028049A2 (pt) 2010-05-05 2015-11-24 Genomatica Inc organismo microbiano de ocorrência não natural e método para produzir butadieno, meio de cultura, butadieno biossintetizado, composição, produto químico orgânico, polímero e uso de butadieno biossintetizado
US20110306734A1 (en) 2010-06-02 2011-12-15 Bayer Materialscience Ag Thermoplastically processable polyurethanes based on succinic acid propionates
MX355342B (es) * 2010-06-08 2018-04-16 Adhesivos sensibles a la presión a base de aceite vegetal.
US8715957B2 (en) 2010-07-26 2014-05-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
WO2012125218A1 (en) 2011-03-14 2012-09-20 Dow Global Technologies Llc Processes for producing terephthalic acid and terephthalic esters
CN102242074B (zh) * 2011-04-12 2014-08-06 叶春 一种兼性厌氧菌的筛选方法
US8580096B2 (en) 2011-09-29 2013-11-12 Uchicago Argonne, Llc Bioprocess utilizing carbon dioxide and electrodeionization
BR112014007306A2 (pt) 2011-09-30 2017-04-04 Bayer Ip Gmbh artigos extrudados homogêneos feitos a partir de poliuretanos termoplasticamente processáveis com base em poliéster-dióis formados a partir de ácido succínico e de 1,3-propanodiol
EP2836078A1 (de) 2012-04-09 2015-02-18 Avery Dennison Corporation Druckempfindliche haftkleber auf basis erneuerbarer ressourcen, uv-härtung davon und entsprechende verfahren
WO2013166075A1 (en) 2012-04-30 2013-11-07 Woods Hole Oceanographic Institution Cobalamin acquisition protein and use thereof
US11932845B2 (en) 2012-06-04 2024-03-19 Genomatica, Inc. Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds
WO2017192925A1 (en) * 2016-05-05 2017-11-09 William Marsh Rice University Improved microbial production of fats
CN110951660B (zh) 2019-12-19 2021-12-03 江南大学 一株固定co2产苹果酸的大肠杆菌工程菌的构建及应用
CN114350718B (zh) * 2021-12-31 2024-06-07 安徽丰原发酵技术工程研究有限公司 一种发酵生产苹果酸的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543759B2 (de) * 1972-06-28 1980-11-07
US4190495A (en) * 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
JPS60114197A (ja) * 1983-11-25 1985-06-20 Agency Of Ind Science & Technol 微生物によるジカルボン酸の製造法
US4871667A (en) * 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
DE3783081T2 (de) * 1986-06-11 1993-04-15 Michigan Biotech Inst Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation.
US5168055A (en) * 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
US5143834A (en) * 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5182199A (en) * 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
AU639237B2 (en) * 1989-04-27 1993-07-22 Biocontrol Systems, Incorporated Precipitate test for microorganisms
US5416020A (en) * 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
FR2702492B1 (fr) * 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
HU213759B (en) * 1993-06-25 1997-09-29 Du Pont Process for the preparation of pyruvic acid
EP0706577B1 (de) * 1993-07-01 1997-08-27 E.I. Du Pont De Nemours And Company Verbessertes Verfahren zur Herstellung von Mischuingen aus Glyoxylsäure und Aminoethylphosphonsäure unter Verwendung eines doppelt angereicherten Mikroorganismus
US5521075A (en) * 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) * 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms

Also Published As

Publication number Publication date
HUP0001997A2 (hu) 2000-10-28
ATE360084T1 (de) 2007-05-15
HU227509B1 (en) 2011-07-28
BR9806822B1 (pt) 2009-05-05
HUP0001997A3 (en) 2002-01-28
DK1012323T3 (da) 2007-06-18
BR9806822A (pt) 2000-05-09
JP3681404B2 (ja) 2005-08-10
AU6052398A (en) 1998-08-25
CN1121500C (zh) 2003-09-17
WO1998033930A1 (en) 1998-08-06
CA2278892A1 (en) 1998-08-06
ES2285757T3 (es) 2007-11-16
EP1012323B1 (de) 2007-04-18
AU724274B2 (en) 2000-09-14
JP2000515389A (ja) 2000-11-21
EP1012323A4 (de) 2002-01-16
DE69837607T2 (de) 2007-12-27
PT1012323E (pt) 2007-05-31
CN1246155A (zh) 2000-03-01
US5869301A (en) 1999-02-09
CA2278892C (en) 2009-02-24
EP1012323A1 (de) 2000-06-28

Similar Documents

Publication Publication Date Title
DE69837607D1 (de) Verfahren zum herstellen von dicarbonsäuren
CA2236472A1 (en) A mutant e. coli strain with increased succinic acid production
DE69429452D1 (de) Herstellungsverfahren einer substanz
DE69807659D1 (de) Verfahren zur erzeugung von korn-förmigem mikroorganismenwachstum in einem reaktor
ATE317911T1 (de) Verfahren zur herstellung von l-aminosäuren durch fermentation
ATE196776T1 (de) Neue mikroorganismen, deren verwendung und verfahren zur herstellung von l-alpha-aminosäuren
MY111441A (en) Method of producing l-glutamic acid by fermentation
KR850004267A (ko) 폴리-d-(-)-3-하이드록시부티르산의 제조방법
PL255683A1 (en) Method of obtaining derivatives of the a-21978c antibiotics
ATE122722T1 (de) Verfahren zur fermentativen oxydation reduzierender disaccharide.
DE3752177D1 (de) Vorrichtung zur Kultivierung von Mikroorganismen
JPS5743685A (en) L-glutamic oxidase
ATE355386T1 (de) Verfahren zur herstellung von l-glutaminsäure durch kontinuierliche gärung
ES8702487A1 (es) Procedimiento para cultivar microorganismos en aerobiosis enun medio nutritivo liquido sometido a una oxigenacion
DE3782333D1 (de) Verfahren und anlage zur herstellung von biogas aus dickfluessigen vergaerbaren medien.
GR3021593T3 (en) Fermentative method of preparing 2-hydroxyphenylacetic acid.
TR200100167T2 (tr) Klavulanik asit üretimi için geliştirilmiş yöntem
DE3782184D1 (de) Verfahren zur fermentativen herstellung von l-aminosaeuren aus alpha-ketocarbonsaeuren.
JPS61124374A (ja) 酢酸からメタンを生成する微生物の培養法
ES8602943A1 (es) Procedimiento para la mejora de la fermentacion de acido clavulanico y sus sales
ATE92964T1 (de) Verfahren zur herstellung von itaconsaeure.
GB1501560A (en) Biological treatment of waste water
FR2364184A1 (fr) Procede de purification d'eaux usees ayant une teneur elevee en substances organiques
KR960009065B1 (en) Preparation process of poly-3-hydroxybutyrate
ATE73852T1 (de) Verfahren zur fermentativen herstellung von larginin.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition