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DE69825056D1 - 2-aminopropan-1,3-diol-verbindungen, ihre medizinische anwendung und zwischenprodukte zu ihrer synthese - Google Patents

2-aminopropan-1,3-diol-verbindungen, ihre medizinische anwendung und zwischenprodukte zu ihrer synthese

Info

Publication number
DE69825056D1
DE69825056D1 DE69825056T DE69825056T DE69825056D1 DE 69825056 D1 DE69825056 D1 DE 69825056D1 DE 69825056 T DE69825056 T DE 69825056T DE 69825056 T DE69825056 T DE 69825056T DE 69825056 D1 DE69825056 D1 DE 69825056D1
Authority
DE
Germany
Prior art keywords
compound
aminopropane
synthesis
intermediate products
medical application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69825056T
Other languages
English (en)
Other versions
DE69825056T2 (de
Inventor
Kunitomo Adachi
Yoshiyuki Aoki
Tokushi Hanano
Koji Teshima
Yukio Hoshino
Tetsuro Fujita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Mitsubishi Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp
Application granted granted Critical
Publication of DE69825056D1 publication Critical patent/DE69825056D1/de
Publication of DE69825056T2 publication Critical patent/DE69825056T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/16—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same carbon atom of an acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69825056T 1997-04-04 1998-04-03 2-aminopropan-1,3-diol-verbindungen, ihre medizinische anwendung und zwischenprodukte zu ihrer synthese Expired - Lifetime DE69825056T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8625597 1997-04-04
JP8625597 1997-04-04
PCT/JP1998/001571 WO1998045249A1 (fr) 1997-04-04 1998-04-03 Composes 2-aminopropane-1,3-diol, leur utilisation pharmaceutique, et intermediaires servant a leur synthese

Publications (2)

Publication Number Publication Date
DE69825056D1 true DE69825056D1 (de) 2004-08-19
DE69825056T2 DE69825056T2 (de) 2005-08-25

Family

ID=13881722

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69830756T Expired - Lifetime DE69830756T2 (de) 1997-04-04 1998-04-03 2-Aminopropan-1,3-diol-Verbindungen, ihre medizinische Anwendung und Zwischenprodukte zu ihrer Synthese
DE69825056T Expired - Lifetime DE69825056T2 (de) 1997-04-04 1998-04-03 2-aminopropan-1,3-diol-verbindungen, ihre medizinische anwendung und zwischenprodukte zu ihrer synthese

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69830756T Expired - Lifetime DE69830756T2 (de) 1997-04-04 1998-04-03 2-Aminopropan-1,3-diol-Verbindungen, ihre medizinische Anwendung und Zwischenprodukte zu ihrer Synthese

Country Status (18)

Country Link
US (2) US6214873B1 (de)
EP (2) EP1319651B1 (de)
JP (1) JP4045364B2 (de)
KR (1) KR100551931B1 (de)
CN (2) CN1137086C (de)
AT (2) ATE298740T1 (de)
AU (1) AU735853B2 (de)
BR (1) BR9808481A (de)
CA (1) CA2286315C (de)
DE (2) DE69830756T2 (de)
DK (2) DK1319651T3 (de)
ES (2) ES2226110T3 (de)
IL (3) IL155066A (de)
NZ (1) NZ500713A (de)
PT (2) PT1002792E (de)
RU (1) RU2198162C2 (de)
SI (2) SI1002792T1 (de)
WO (1) WO1998045249A1 (de)

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Also Published As

Publication number Publication date
EP1002792B1 (de) 2004-07-14
IL155065A0 (en) 2003-10-31
IL132208A (en) 2003-07-31
NZ500713A (en) 2000-07-28
SI1002792T1 (en) 2004-12-31
EP1319651A2 (de) 2003-06-18
US6214873B1 (en) 2001-04-10
RU2198162C2 (ru) 2003-02-10
KR100551931B1 (ko) 2006-02-16
PT1002792E (pt) 2004-12-31
DE69825056T2 (de) 2005-08-25
PT1319651E (pt) 2005-09-30
EP1002792A1 (de) 2000-05-24
USRE39072E1 (en) 2006-04-18
DE69830756T2 (de) 2006-05-04
WO1998045249A1 (fr) 1998-10-15
KR20010006004A (ko) 2001-01-15
CN1290819C (zh) 2006-12-20
IL155065A (en) 2004-01-04
SI1319651T1 (en) 2005-10-31
CN1480450A (zh) 2004-03-10
CA2286315C (en) 2007-03-06
CA2286315A1 (en) 1998-10-15
DK1002792T3 (da) 2004-11-22
BR9808481A (pt) 2000-05-23
ES2240868T3 (es) 2005-10-16
AU735853B2 (en) 2001-07-19
ATE298740T1 (de) 2005-07-15
CN1137086C (zh) 2004-02-04
DE69830756D1 (de) 2005-08-04
EP1319651B1 (de) 2005-06-29
DK1319651T3 (da) 2005-08-01
ATE271028T1 (de) 2004-07-15
JP4045364B2 (ja) 2008-02-13
IL155066A0 (en) 2003-10-31
CN1259117A (zh) 2000-07-05
ES2226110T3 (es) 2005-03-16
AU6523098A (en) 1998-10-30
IL132208A0 (en) 2001-03-19
EP1319651A3 (de) 2004-01-02
EP1002792A4 (de) 2002-03-20
IL155066A (en) 2004-06-20

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