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DE69731003D1 - Blutzuckersenkende und lipidsenkende verbindungen - Google Patents

Blutzuckersenkende und lipidsenkende verbindungen

Info

Publication number
DE69731003D1
DE69731003D1 DE69731003T DE69731003T DE69731003D1 DE 69731003 D1 DE69731003 D1 DE 69731003D1 DE 69731003 T DE69731003 T DE 69731003T DE 69731003 T DE69731003 T DE 69731003T DE 69731003 D1 DE69731003 D1 DE 69731003D1
Authority
DE
Germany
Prior art keywords
lowering
compounds
lipid
glucose
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69731003T
Other languages
English (en)
Inventor
J Dominianni
H Gritton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE69731003D1 publication Critical patent/DE69731003D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69731003T 1996-07-01 1997-06-30 Blutzuckersenkende und lipidsenkende verbindungen Expired - Lifetime DE69731003D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2101796P 1996-07-01 1996-07-01
PCT/US1997/011514 WO1998000403A1 (en) 1996-07-01 1997-06-30 Hypoglycemic and hypolipidemic compounds

Publications (1)

Publication Number Publication Date
DE69731003D1 true DE69731003D1 (de) 2004-11-04

Family

ID=21801860

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69731003T Expired - Lifetime DE69731003D1 (de) 1996-07-01 1997-06-30 Blutzuckersenkende und lipidsenkende verbindungen

Country Status (10)

Country Link
US (1) US6121282A (de)
EP (1) EP1019378B1 (de)
JP (1) JP2000515501A (de)
AT (1) ATE277907T1 (de)
AU (1) AU3513497A (de)
CA (1) CA2259431A1 (de)
DE (1) DE69731003D1 (de)
IL (1) IL121203A (de)
WO (1) WO1998000403A1 (de)
ZA (1) ZA975867B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI302149B (en) 1999-09-22 2008-10-21 Bristol Myers Squibb Co Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method
US6414002B1 (en) 1999-09-22 2002-07-02 Bristol-Myers Squibb Company Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
CA2393265A1 (en) * 1999-12-03 2001-06-07 Kyoto Pharmaceutical Industries, Ltd. Novel heterocyclic compounds and salts thereof and medicinal use of the same
US7187947B1 (en) 2000-03-28 2007-03-06 Affinity Labs, Llc System and method for communicating selected information to an electronic device
BR0209735A (pt) 2001-05-29 2004-07-27 Kyoto Pharma Ind Derivados heterocìclicos e uso medicinal destes
NZ530358A (en) * 2001-05-29 2005-04-29 Kyoto Pharma Ind Heterocyclic compound and medicinal use thereof
EP1405848B1 (de) * 2001-06-18 2008-05-07 Ono Pharmaceutical Co., Ltd. Tetrahydrochinolinderivatverbindung und die verbindung als wirkstoff enthaltendes arzneimittel
CA2463922C (en) 2001-06-27 2013-07-16 4 Media, Inc. Improved media delivery platform
US6716842B2 (en) 2002-04-05 2004-04-06 Warner-Lambert Company, Llc Antidiabetic agents
JP4579681B2 (ja) 2002-07-09 2010-11-10 ブリストル−マイヤーズ スクイブ カンパニー 抗糖尿病薬および抗肥満薬として有用な置換ヘテロシクロ誘導体および方法
WO2004106276A1 (ja) 2003-05-30 2004-12-09 Takeda Pharmaceutical Company Limited 縮合環化合物
JP4805552B2 (ja) * 2003-05-30 2011-11-02 武田薬品工業株式会社 縮合環化合物
BRPI0507462A (pt) 2004-02-04 2007-07-10 Pfizer Prod Inc compostos de quinolina substituìdos
US20080186971A1 (en) * 2007-02-02 2008-08-07 Tarari, Inc. Systems and methods for processing access control lists (acls) in network switches using regular expression matching logic
WO2012033195A1 (ja) * 2010-09-10 2012-03-15 京都薬品工業株式会社 複素環化合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988720A (en) * 1985-05-28 1991-01-29 Beecham Group P.L.C. Novel treatment of hyperglycaemia
CA1338625C (en) * 1988-06-09 1996-10-01 Kyowa Hakko Kogyo Co., Ltd. Tricyclic compounds
US4902695A (en) * 1989-02-13 1990-02-20 Eli Lilly And Company Excitatory amino acid receptor antagonists
AU6368090A (en) * 1989-10-03 1991-04-11 Warner-Lambert Company Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
KR0180248B1 (ko) * 1991-06-07 1999-03-20 오오쓰까 아끼히꼬 항당뇨병약품
US5246943A (en) * 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
PT604657E (pt) * 1992-05-21 2000-04-28 Otsuka Pharma Co Ltd Derivado de diester fosfonico
US5236934A (en) * 1992-08-26 1993-08-17 E. I. Du Pont De Nemours And Company 1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS disorders
JP2845743B2 (ja) * 1992-12-28 1999-01-13 三菱化学株式会社 新規なナフタレン誘導体
GB9311661D0 (en) * 1993-06-05 1993-07-21 Smithkline Beecham Plc Novel compounds
US5591862A (en) * 1993-06-11 1997-01-07 Takeda Chemical Industries, Ltd. Tetrazole derivatives, their production and use
CA2172125A1 (en) * 1993-09-30 1995-04-06 S. Jane Desolms Inhibitors of farnesyl-protein transferase
US5571792A (en) * 1994-06-30 1996-11-05 Warner-Lambert Company Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase
US5616819A (en) * 1995-08-28 1997-04-01 Laroche Industries Inc. Process for preparing fluorinated aliphatic compounds
US5885327A (en) * 1995-09-12 1999-03-23 Henkel Corporation Process for the recovery of gold
DE19535243A1 (de) * 1995-09-22 1997-03-27 Bayer Ag Neue Zwischenprodukte für die Synthese von Bisphosphinverbindungen

Also Published As

Publication number Publication date
CA2259431A1 (en) 1998-01-08
IL121203A (en) 2001-04-30
EP1019378A1 (de) 2000-07-19
US6121282A (en) 2000-09-19
ATE277907T1 (de) 2004-10-15
EP1019378A4 (de) 2001-09-26
JP2000515501A (ja) 2000-11-21
IL121203A0 (en) 1997-11-20
WO1998000403A1 (en) 1998-01-08
EP1019378B1 (de) 2004-09-29
AU3513497A (en) 1998-01-21
ZA975867B (en) 1999-01-04

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Legal Events

Date Code Title Description
8332 No legal effect for de