[go: up one dir, main page]

DE69626544T2 - Arzneistoffe - Google Patents

Arzneistoffe Download PDF

Info

Publication number
DE69626544T2
DE69626544T2 DE69626544T DE69626544T DE69626544T2 DE 69626544 T2 DE69626544 T2 DE 69626544T2 DE 69626544 T DE69626544 T DE 69626544T DE 69626544 T DE69626544 T DE 69626544T DE 69626544 T2 DE69626544 T2 DE 69626544T2
Authority
DE
Germany
Prior art keywords
drug substances
cryptophycin compounds
novel cryptophycin
disrupting
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69626544T
Other languages
English (en)
Other versions
DE69626544D1 (de
Inventor
Chuan Shih
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hawaii at Manoa
Wayne State University
Eli Lilly and Co
Original Assignee
University of Hawaii at Manoa
Wayne State University
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hawaii at Manoa, Wayne State University, Eli Lilly and Co filed Critical University of Hawaii at Manoa
Application granted granted Critical
Publication of DE69626544D1 publication Critical patent/DE69626544D1/de
Publication of DE69626544T2 publication Critical patent/DE69626544T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69626544T 1995-12-22 1996-12-20 Arzneistoffe Expired - Fee Related DE69626544T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US914595P 1995-12-22 1995-12-22
US2507996P 1996-08-30 1996-08-30
PCT/US1996/020633 WO1997023211A1 (en) 1995-12-22 1996-12-20 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
DE69626544D1 DE69626544D1 (de) 2003-04-10
DE69626544T2 true DE69626544T2 (de) 2004-01-15

Family

ID=26679113

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69626544T Expired - Fee Related DE69626544T2 (de) 1995-12-22 1996-12-20 Arzneistoffe

Country Status (8)

Country Link
EP (1) EP0869786B1 (de)
JP (1) JP2000502351A (de)
AT (1) ATE233745T1 (de)
AU (1) AU1469097A (de)
CA (1) CA2241086A1 (de)
DE (1) DE69626544T2 (de)
ES (1) ES2194129T3 (de)
WO (1) WO1997023211A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU722492B2 (en) * 1996-08-30 2000-08-03 University Of Hawaii Pharmaceutical compounds
US6680311B1 (en) 1996-08-30 2004-01-20 Eli Lilly And Company Cryptophycin compounds
HUP0000212A3 (en) * 1996-09-06 2001-12-28 Wayne State University Detroit Process to prepare cryptophycin derivatives and intermediates thereof
CA2281107A1 (en) * 1997-02-26 1998-09-03 Eli Lilly And Company Tripeptide and tetrapeptide pharmaceutical compounds
PL335347A1 (en) * 1997-02-26 2000-04-25 Lilly Co Eli Selective epoxidising process for use in production of pharmaceutic compounds
EP0870506A1 (de) * 1997-04-11 1998-10-14 Eli Lilly And Company Zusammentsetzungen enthaltend ein Cryptophycin Derivat in Kombination mit einem synchronisierten Wirkstoff oder Aktivierungsmittel zur Behandlung von Krebs
US6103913A (en) * 1998-10-16 2000-08-15 Eli Lilly And Company Process for preparing enollactone derivatives
US6376230B1 (en) 1998-10-16 2002-04-23 Eli Lilly And Company Stereoselective process for producing intermediates of cryptophycins
JP4776843B2 (ja) 1999-10-01 2011-09-21 イムノゲン インコーポレーティッド 免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
GB8814813D0 (en) * 1988-06-22 1988-07-27 Beecham Group Plc Novel compounds
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
CA2179490A1 (en) * 1993-12-21 1995-06-29 Trimurtulu Golakoti New cryptophycins
JP2000501067A (ja) * 1995-08-30 2000-02-02 イーライ・リリー・アンド・カンパニー 医薬化合物
CA2264297A1 (en) * 1996-08-30 1998-03-05 Chuan Shih Pharmaceutical compounds
AU4330097A (en) * 1996-08-30 1998-03-19 Eli Lilly And Company Pharmaceutical compounds

Also Published As

Publication number Publication date
ATE233745T1 (de) 2003-03-15
JP2000502351A (ja) 2000-02-29
DE69626544D1 (de) 2003-04-10
AU1469097A (en) 1997-07-17
EP0869786B1 (de) 2003-03-05
ES2194129T3 (es) 2003-11-16
CA2241086A1 (en) 1997-07-03
EP0869786A1 (de) 1998-10-14
WO1997023211A1 (en) 1997-07-03
EP0869786A4 (de) 1999-04-14

Similar Documents

Publication Publication Date Title
ATE339406T1 (de) Chinazoline verbindungen als heilmittel
BR9711986A (pt) Compostos farmac-uticos
CY1118334T1 (el) Χρηση δαπτομυκινης
DE602004027936D1 (de) Tocopherolmodifizierte therapeutische arzneimittelverbindung
AU2002236765A1 (en) Pharmaceutical combination for the treatment of cancer containing a 4-quinazolineamine and another anti-neoplastic agent
MY118151A (en) Pharmaceutical formulations containing voriconazole.
EE200000320A (et) Uudsed ühendid
SE9704544D0 (sv) Novel compounds
TR200101103T2 (tr) CGMP PDE-İnhibitörü içeren kontrollu serbest bırakılan farmasötik formülasyonlar
SE9704546D0 (sv) Novel compounds
ATE240303T1 (de) 1,2,4-triazol-3-thion verbindungen
DE69626544T2 (de) Arzneistoffe
GB9907571D0 (en) Compounds
DE59608150D1 (de) Transdermales therapeutisches system (tts) zur verabreichung von testosteron
HUP0000110A2 (hu) Azaciklusos, azabiciklusos vagy tetrahidropiridinszármazékokat tartalmazó, fájdalom kezelésére alkalmas gyógyászati készítmények
SE0004827D0 (sv) Therapeutic compounds
NO20020914D0 (no) Alkoksy-substituerte benzimidazolforbindelser, preparater inneholdende slike samt anvendelser derav
MX9801604A (es) Compuestos farmaceuticos.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee