DE69714019D1 - 1,4-dihydropyridin-verbindungen als bradykinin-antagonisten - Google Patents

1,4-dihydropyridin-verbindungen als bradykinin-antagonisten

Info

Publication number: DE69714019D1
Authority: DE; Germany
Prior art keywords: dihydropyridine compounds; bradykinine; antagonists; bradykinine antagonists; dihydropyridine
Prior art date: 1996-02-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69714019T

Other languages

English (en)

Other versions

DE69714019T2 (de

Inventor

Takafumi Ikeda

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Corp Belgium

Pfizer Inc

Original Assignee

Pfizer Corp Belgium

Pfizer Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-19

Filing date

1997-01-27

Publication date

2002-08-22

1997-01-27 Application filed by Pfizer Corp Belgium, Pfizer Inc filed Critical Pfizer Corp Belgium

2002-08-22 Application granted granted Critical

2002-08-22 Publication of DE69714019D1 publication Critical patent/DE69714019D1/de

2002-11-14 Publication of DE69714019T2 publication Critical patent/DE69714019T2/de

2017-01-28 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Virology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)

DE69714019T 1996-02-19 1997-01-27 1,4-dihydropyridin-verbindungen als bradykinin-antagonisten Expired - Fee Related DE69714019T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IB9600132		1996-02-19
PCT/IB1997/000058 WO1997030048A1 (en)	1996-02-19	1997-01-27	1,4-dihydropyridine compounds as bradykinin antagonists

Publications (2)

Publication Number	Publication Date
DE69714019D1 true DE69714019D1 (de)	2002-08-22
DE69714019T2 DE69714019T2 (de)	2002-11-14

Family

ID=11004406

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69714019T Expired - Fee Related DE69714019T2 (de)	1996-02-19	1997-01-27	1,4-dihydropyridin-verbindungen als bradykinin-antagonisten

Country Status (34)

Country	Link
US (1)	US6131226A (de)
EP (1)	EP0882044B1 (de)
JP (1)	JP3167335B2 (de)
KR (1)	KR19990082678A (de)
CN (1)	CN1211251A (de)
AR (1)	AR005841A1 (de)
AT (1)	ATE220676T1 (de)
AU (1)	AU1396497A (de)
BG (1)	BG102678A (de)
BR (1)	BR9707568A (de)
CA (1)	CA2245857C (de)
CO (1)	CO4650041A1 (de)
CZ (1)	CZ258698A3 (de)
DE (1)	DE69714019T2 (de)
DK (1)	DK0882044T3 (de)
ES (1)	ES2177921T3 (de)
HN (1)	HN1997000013A (de)
HR (1)	HRP970094A2 (de)
HU (1)	HUP9902810A3 (de)
ID (1)	ID16434A (de)
IL (1)	IL124867A0 (de)
IS (1)	IS4783A (de)
MA (1)	MA26419A1 (de)
NO (1)	NO983776L (de)
NZ (1)	NZ325455A (de)
OA (1)	OA10712A (de)
PE (1)	PE36298A1 (de)
PL (1)	PL328514A1 (de)
PT (1)	PT882044E (de)
SI (1)	SI0882044T1 (de)
TN (1)	TNSN97037A1 (de)
TR (1)	TR199801593T2 (de)
WO (1)	WO1997030048A1 (de)
ZA (1)	ZA971357B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH11106375A (ja) *	1997-08-18	1999-04-20	Pfizer Pharmaceut Inc	ブラジキニンアンタゴニストとしての光学的に活性な１，４−ジヒドロピリジン化合物
US6653313B2 (en) *	2000-08-10	2003-11-25	Warner-Lambert Company Llc	1,4-dihydropyridine compounds as bradykinin antagonists
GB0427281D0 (en) *	2004-12-14	2005-01-12	3M Innovative Properties Co	Methods of providing medicinal metal components having through holes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5120750A (en) *	1989-01-17	1992-06-09	Synphar Laboratories, Inc.	Generation of 1,4-dihydropyridine derivatives
WO1996006083A1 (en) *	1994-08-24	1996-02-29	Pfizer Pharmaceuticals Inc.	2-(piperazinyl-1-carbonylmethyl)-1,4-dihydropyridines as bradykinin antagonists
MX9701245A (es) *	1996-02-19	1998-04-30	Pfizer	Compuestos de 1,4 dihidropiridina.

1996
- 1996-02-18 TN TNTNSN97037A patent/TNSN97037A1/fr unknown
1997
- 1997-01-27 AU AU13964/97A patent/AU1396497A/en not_active Abandoned
- 1997-01-27 PT PT97900401T patent/PT882044E/pt unknown
- 1997-01-27 SI SI9730361T patent/SI0882044T1/xx unknown
- 1997-01-27 AT AT97900401T patent/ATE220676T1/de not_active IP Right Cessation
- 1997-01-27 KR KR1019980706424A patent/KR19990082678A/ko not_active Application Discontinuation
- 1997-01-27 JP JP52913897A patent/JP3167335B2/ja not_active Expired - Fee Related
- 1997-01-27 DE DE69714019T patent/DE69714019T2/de not_active Expired - Fee Related
- 1997-01-27 ES ES97900401T patent/ES2177921T3/es not_active Expired - Lifetime
- 1997-01-27 CZ CZ982586A patent/CZ258698A3/cs unknown
- 1997-01-27 CA CA002245857A patent/CA2245857C/en not_active Expired - Fee Related
- 1997-01-27 IL IL12486797A patent/IL124867A0/xx unknown
- 1997-01-27 HN HN1997000013A patent/HN1997000013A/es unknown
- 1997-01-27 EP EP97900401A patent/EP0882044B1/de not_active Expired - Lifetime
- 1997-01-27 NZ NZ325455A patent/NZ325455A/xx unknown
- 1997-01-27 US US09/125,137 patent/US6131226A/en not_active Expired - Fee Related
- 1997-01-27 HU HU9902810A patent/HUP9902810A3/hu unknown
- 1997-01-27 CN CN97192240A patent/CN1211251A/zh active Pending
- 1997-01-27 BR BR9707568A patent/BR9707568A/pt active Search and Examination
- 1997-01-27 WO PCT/IB1997/000058 patent/WO1997030048A1/en active IP Right Grant
- 1997-01-27 DK DK97900401T patent/DK0882044T3/da active
- 1997-01-27 PL PL97328514A patent/PL328514A1/xx unknown
- 1997-01-27 TR TR1998/01593T patent/TR199801593T2/xx unknown
- 1997-02-10 PE PE1997000085A patent/PE36298A1/es not_active Application Discontinuation
- 1997-02-13 CO CO97007547A patent/CO4650041A1/es unknown
- 1997-02-17 AR ARP970100614A patent/AR005841A1/es unknown
- 1997-02-18 HR HRPCT/IB96/00132A patent/HRP970094A2/xx not_active Application Discontinuation
- 1997-02-18 ID IDP970467A patent/ID16434A/id unknown
- 1997-02-18 MA MA24498A patent/MA26419A1/fr unknown
- 1997-02-18 ZA ZA971357A patent/ZA971357B/xx unknown
1998
- 1998-06-25 IS IS4783A patent/IS4783A/is unknown
- 1998-07-10 OA OA9800111A patent/OA10712A/en unknown
- 1998-08-10 BG BG102678A patent/BG102678A/xx unknown
- 1998-08-18 NO NO983776A patent/NO983776L/no unknown

Also Published As

Publication number	Publication date
TNSN97037A1 (fr)	2005-03-15
DE69714019T2 (de)	2002-11-14
CN1211251A (zh)	1999-03-17
CA2245857A1 (en)	1997-08-21
AU1396497A (en)	1997-09-02
HRP970094A2 (en)	1998-06-30
BR9707568A (pt)	1999-07-27
ID16434A (id)	1997-09-25
NZ325455A (en)	1999-07-29
NO983776D0 (no)	1998-08-18
ATE220676T1 (de)	2002-08-15
IL124867A0 (en)	1999-01-26
TR199801593T2 (xx)	1999-12-21
CO4650041A1 (es)	1998-09-03
AR005841A1 (es)	1999-07-14
CZ258698A3 (cs)	1999-06-16
KR19990082678A (ko)	1999-11-25
WO1997030048A1 (en)	1997-08-21
NO983776L (no)	1998-08-18
HUP9902810A3 (en)	2000-09-28
SI0882044T1 (en)	2002-10-31
PE36298A1 (es)	1998-07-18
JP3167335B2 (ja)	2001-05-21
US6131226A (en)	2000-10-17
ZA971357B (en)	1998-08-18
PT882044E (pt)	2002-11-29
MA26419A1 (fr)	2004-12-20
JPH11507949A (ja)	1999-07-13
EP0882044B1 (de)	2002-07-17
BG102678A (en)	1999-04-30
CA2245857C (en)	2002-10-01
OA10712A (en)	2001-06-04
DK0882044T3 (da)	2002-09-02
HN1997000013A (es)	1997-06-26
ES2177921T3 (es)	2002-12-16
PL328514A1 (en)	1999-02-01
IS4783A (is)	1998-06-25
HUP9902810A2 (hu)	2000-05-28
EP0882044A1 (de)	1998-12-09

Publication	Publication Date	Title
ID17259A (id)	1997-12-11	Fluorina mengandung turunan piperidina 1,4-disubtitusikan
DE69531331D1 (de)	2003-08-28	Phenylpiperidinderivate als neurokinin antagonists
EE9600186A (et)	1997-08-15	Neurokiniini (tahhüülkiniini) antagonistid
ATE297898T1 (de)	2005-07-15	4-carboxamino-2-subsitutierte-1,2,3,4- tetrahydrochinoline als cetp inhibitoren
ATE277906T1 (de)	2004-10-15	4-carboxamino-2-methyl-1,2,3,4- tetrahydrochinoline als cetp inhibitoren
ATE340176T1 (de)	2006-10-15	Substituierte 6,5-heterobicyclische-derivate
DK0925298T3 (da)	2004-08-09	Substituerede 6,6-heterobicykliske derivater
ID24583A (id)	2000-07-27	Turunan-turunan 1,2,3,4-tetrahidronaftalena tersubstitusi
NO2006016I1 (no)	2006-11-27	7,8,9,10-tetrahydro-6H-6,10-metanoazepinoÄ4,5-gÜkinoksalintartrat
PT993456E (pt)	2005-01-31	4,5-diaril-imidazoles 2-substituidos
ATE233260T1 (de)	2003-03-15	Muscarin-antagonisten
DE69607178D1 (de)	2000-04-20	Mikroemulsionsförmige Desinfektionszusammensetzung
FI971685A0 (fi)	1997-04-18	Takykiniini-antagonisteja
FI960727L (fi)	1996-02-16	Neurokiniiniantagonisteina käyttökelpoiset heterosyklit
DE69718771D1 (de)	2003-03-06	Substituierte 1,2,3,4-tetrahydronaphthalinderivate
ID18685A (id)	1998-04-30	Senyawa trisiklik tersubstitusi
DE59507222D1 (de)	1999-12-16	Substituierte 1,2,3,4-tetrahydro-5-nitro-pyrimidine
DE69626220D1 (de)	2003-03-20	3-azetidinylalkylpiperidine oder -pyrrolidine als tachykinin antagonisten
DE69718786D1 (de)	2003-03-06	Benzoxazinone als dopamine -d4- rezeptor-antagonisten
DE69735811D1 (de)	2006-06-08	Piperazinoderivate als neurokinin-antagonisten
DE69714019D1 (de)	2002-08-22	1,4-dihydropyridin-verbindungen als bradykinin-antagonisten
ID26508A (id)	2001-01-11	Oksim-oksim tersubstitusi sebagai antagonis-antagonis neurokinin
DK1068200T3 (da)	2005-06-20	2,4,4-trisubstituerede-1,3-dioxolanfungicider
ID24047A (id)	2000-07-06	Turunan 5-tersubstitusi-3-oksaziazolil 1,6-naftiridin-2 1h-on
KR950700297A (ko)	1995-01-16	5-HT3-수용체 길항제로서의 2,6-메타노-2H-퀴놀리진 유도체(2,6-Methano-2H-quinolizin derivative as 5-HT3-receptor antagonist)

Legal Events

Date	Code	Title	Description
2003-08-14	8364	No opposition during term of opposition
2007-11-15	8339	Ceased/non-payment of the annual fee