|
US5891685A
(en)
*
|
1996-06-03 |
1999-04-06 |
Mitsubishi Chemical Corporation |
Method for producing ester of (S)-γ-halogenated-β-hydroxybutyric acid
|
|
KR100506134B1
(ko)
|
1997-02-07 |
2005-08-08 |
카네카 코포레이션 |
신규한 카르보닐 환원효소 및 이것을 코딩하는 유전자 및 이러한 환원효소 및 유전자 이용방법
|
|
KR20010033541A
(ko)
*
|
1997-12-25 |
2001-04-25 |
나가타 코이치 |
신규 미생물 및 그것을 사용한 폴리올의 제조방법
|
|
JP4012299B2
(ja)
*
|
1998-02-25 |
2007-11-21 |
ダイセル化学工業株式会社 |
ハロゲン置換を含む光学活性アルコールの製造方法
|
|
KR100461561B1
(ko)
*
|
1998-07-24 |
2005-04-06 |
삼성정밀화학 주식회사 |
(s)-3-카르복시-4-브로모부티르산의 제조방법
|
|
GB0011120D0
(en)
*
|
2000-05-09 |
2000-06-28 |
Avecia Ltd |
Process
|
|
JP4578240B2
(ja)
*
|
2002-08-09 |
2010-11-10 |
コデクシス， インコーポレイテッド |
４−置換３−ヒドロキシ酪酸誘導体の生成のための酵素的プロセス
|
|
EP1660669A4
(de)
*
|
2003-08-11 |
2008-10-01 |
Codexis Inc |
Enzymatische verfahren zur herstellung 4-substituierter 3-hydroxybuttersäure-derivate und von mit vicinalem cyano, hydroxy substituierten carbonsäureestern
|
|
DK1725249T3
(en)
|
2003-11-06 |
2014-03-17 |
Seattle Genetics Inc |
Monomethylvaline compounds capable of conjugating to ligands.
|
|
EP1753463A2
(de)
|
2004-06-01 |
2007-02-21 |
Genentech, Inc. |
Antikörper-wirkstoff-konjugate und verfahren
|
|
US7521541B2
(en)
|
2004-09-23 |
2009-04-21 |
Genetech Inc. |
Cysteine engineered antibodies and conjugates
|
|
EP1817336B1
(de)
|
2004-11-12 |
2019-01-09 |
Seattle Genetics, Inc. |
Auristatine mit einer aminobenzoesäureeinheit am n-ende
|
|
WO2007008848A2
(en)
*
|
2005-07-07 |
2007-01-18 |
Seattle Genetics, Inc. |
Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus
|
|
ES2708763T3
(es)
|
2005-07-07 |
2019-04-11 |
Seattle Genetics Inc |
Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C
|
|
US7879585B2
(en)
*
|
2006-10-02 |
2011-02-01 |
Codexis, Inc. |
Ketoreductase enzymes and uses thereof
|
|
KR101460816B1
(ko)
|
2006-12-07 |
2014-11-12 |
에프. 호프만-라 로슈 아게 |
포스포이노시타이드 3-키나제 억제제 화합물 및 그의 사용 방법
|
|
CN101627116B
(zh)
*
|
2007-02-08 |
2013-07-10 |
科德克希思公司 |
酮还原酶及其用途
|
|
NZ583367A
(en)
|
2007-07-16 |
2012-10-26 |
Genentech Inc |
Anti-cd79b antibodies and immunoconjugates and methods of use
|
|
BRPI0813514A2
(pt)
|
2007-07-16 |
2019-09-24 |
Genentech Inc |
anticorpos anti-cd79b humanizados e imunoconjugados e métodos de uso
|
|
CN101784669B
(zh)
|
2007-08-24 |
2015-02-18 |
科德克希思公司 |
用于(r)-3-羟基四氢噻吩的立体选择性制备的改善的酮还原酶多肽
|
|
WO2009036404A2
(en)
|
2007-09-13 |
2009-03-19 |
Codexis, Inc. |
Ketoreductase polypeptides for the reduction of acetophenones
|
|
JP5736171B2
(ja)
|
2007-09-24 |
2015-06-17 |
ジェネンテック， インコーポレイテッド |
チアゾロピリミジンｐｉ３ｋ阻害剤化合物および使用方法
|
|
KR20100061571A
(ko)
*
|
2007-09-28 |
2010-06-07 |
코덱시스, 인코포레이티드 |
케토리덕타제 폴리펩티드 및 이의 용도
|
|
SI2205727T1
(sl)
|
2007-10-01 |
2015-09-30 |
Codexis, Inc. |
Polipeptidi ketoreduktaze za izdelavo azetidinona
|
|
EP2657253B1
(de)
|
2008-01-31 |
2017-07-19 |
Genentech, Inc. |
Anti-CD79b-Antikörper und Immunokonjugate sowie Verwendungsverfahren
|
|
IL274393B
(en)
|
2008-03-18 |
2022-09-01 |
Genentech Inc |
Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
|
|
EP2265283B1
(de)
|
2008-03-18 |
2014-09-03 |
Seattle Genetics, Inc. |
Auristatin-arznei-linker-konjugate
|
|
WO2010009124A2
(en)
|
2008-07-15 |
2010-01-21 |
Genentech, Inc. |
Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
|
|
US8288131B2
(en)
|
2008-08-27 |
2012-10-16 |
Codexis, Inc. |
Ketoreductase polypeptides and uses thereof
|
|
ES2560459T3
(es)
*
|
2008-08-27 |
2016-02-19 |
Codexis, Inc. |
Polipéptidos cetorreductasa para la producción de una 3-aril-3-hidroxipropanamina a partir de una 3-aril-3-cetopropanamina
|
|
WO2010025287A2
(en)
*
|
2008-08-27 |
2010-03-04 |
Codexis, Inc. |
Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
|
|
US8273554B2
(en)
|
2008-08-29 |
2012-09-25 |
Codexis, Inc. |
Ketoreductase polypeptides for the stereoselective production of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
|
|
CA2753285A1
(en)
|
2009-03-12 |
2010-09-16 |
Genentech, Inc. |
Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
|
|
WO2010120561A1
(en)
|
2009-04-01 |
2010-10-21 |
Genentech, Inc. |
Anti-fcrh5 antibodies and immunoconjugates and methods of use
|
|
HUE055413T2
(hu)
|
2009-06-22 |
2021-11-29 |
Codexis Inc |
Ketoreduktáz-közvetített sztereoszelektív útvonal alfa-klóralkoholokhoz
|
|
AU2010268690B2
(en)
|
2009-07-03 |
2011-11-10 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
|
WO2011022548A2
(en)
|
2009-08-19 |
2011-02-24 |
Codexis, Inc. |
Ketoreductase polypeptides for the preparation of phenylephrine
|
|
CA2770252C
(en)
|
2009-09-08 |
2018-06-12 |
F. Hoffmann-La Roche Ag |
4-substituted pyridin-3-yl-carboxamide compounds and uses thereof for treating cancer
|
|
DK2483278T3
(da)
|
2009-09-28 |
2014-01-13 |
Hoffmann La Roche |
Benzoxazepin pi3k-inhibitorforbindelser og deres anvendelse i behandlingen af cancer
|
|
PE20140918A1
(es)
|
2009-09-28 |
2014-08-06 |
Hoffmann La Roche |
Compuestos de benzoxepina inhibidores de la pi3k
|
|
US10584181B2
(en)
|
2009-12-04 |
2020-03-10 |
Genentech, Inc. |
Methods of making and using multispecific antibody panels and antibody analog panels
|
|
WO2011075786A1
(en)
|
2009-12-23 |
2011-06-30 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them 2
|
|
US9080192B2
(en)
|
2010-02-10 |
2015-07-14 |
Codexis, Inc. |
Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
|
|
PT2528625E
(pt)
|
2010-04-15 |
2013-10-17 |
Spirogen Sarl |
Pirrolobenzodiazepinas e conjugados das mesmas
|
|
WO2011140219A1
(en)
|
2010-05-04 |
2011-11-10 |
Codexis, Inc. |
Biocatalysts for ezetimibe synthesis
|
|
CN103068406B
(zh)
|
2010-06-08 |
2017-06-30 |
基因泰克公司 |
半胱氨酸改造的抗体和偶联物
|
|
JP5889912B2
(ja)
|
2010-11-17 |
2016-03-22 |
ジェネンテック， インコーポレイテッド |
アラニニルメイタンシノール抗体コンジュゲート
|
|
AR084312A1
(es)
|
2010-12-16 |
2013-05-08 |
Genentech Inc |
Compuestos triciclicos inhibidores de la pi3k y composiciones farmaceuticas
|
|
CA2831307A1
(en)
|
2011-03-30 |
2012-10-04 |
Arizona Board Of Regents, For And On Behalf Of, Arizona State Universi |
Auristatin tyramine phosphate salts and auristatin aminoquinoline derivatives and prodrugs thereof
|
|
RS56759B2
(sr)
|
2011-04-01 |
2024-10-31 |
Genentech Inc |
Kombinacija akt inhibitor jedinjenja i abiraterona za upotrebu pri terapeutskim tretiranjima
|
|
MX2013011333A
(es)
|
2011-04-01 |
2014-04-16 |
Genentech Inc |
Combinaciones de compuestos inhibidores de akt y mek, y metodos de uso.
|
|
AU2012245073B2
(en)
|
2011-04-21 |
2016-02-11 |
Garvan Institute Of Medical Research |
Modified variable domain molecules and methods for producing and using them b
|
|
ES2907071T3
(es)
|
2011-05-19 |
2022-04-21 |
Fundacion Del Sector Publico Estatal Centro Nac De Investigaciones Oncologicas Carlos Iii F S P Cnio |
Compuestos macrocíclicos como inhibidores de proteína quinasas
|
|
EP2524918A1
(de)
|
2011-05-19 |
2012-11-21 |
Centro Nacional de Investigaciones Oncológicas (CNIO) |
Imidazopyrazinderivate als Kinase Inhibitoren
|
|
CA2850371C
(en)
|
2011-10-14 |
2020-06-30 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
BR112014010391A2
(pt)
|
2011-11-03 |
2017-04-18 |
Hoffmann La Roche |
composto, composição farmacêutica, processo de produção de uma composição farmacêutica, método de tratamento, kit e uso de uma composição farmacêutica
|
|
UA111756C2
(uk)
|
2011-11-03 |
2016-06-10 |
Ф. Хоффманн-Ля Рош Аг |
Сполуки гетероарилпіридону та азапіридону як інгібітори тирозинкінази брутона
|
|
AR088642A1
(es)
|
2011-11-03 |
2014-06-25 |
Genentech Inc |
Compuestos de piperazina alquilados
|
|
CA2853967A1
(en)
|
2011-11-03 |
2013-05-10 |
F. Hoffmann-La Roche Ag |
8-fluorophthalazin-1 (2h) -one compounds as inhibitors of btk activity
|
|
HUE046089T2
(hu)
|
2011-11-18 |
2020-01-28 |
Codexis Inc |
Biokatalizátorok hidroxi-szubsztituált karbamátok elõállításához
|
|
SG11201407537YA
(en)
|
2012-06-08 |
2014-12-30 |
Hoffmann La Roche |
Mutant selectivity and combinations of a phosphoinositide 3 kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer
|
|
DE102012017026A1
(de)
|
2012-08-28 |
2014-03-06 |
Forschungszentrum Jülich GmbH |
Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen
|
|
EP2890698B1
(de)
|
2012-08-30 |
2017-03-01 |
F. Hoffmann-La Roche AG |
Dioxin- und oxazin-[2,3-d]-pyrimidin-pi3k-hemmerverbindungen und anwendungsverfahren dafür
|
|
CN109134599A
(zh)
|
2012-10-12 |
2019-01-04 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其结合物
|
|
HUE052835T2
(hu)
|
2012-10-12 |
2021-05-28 |
Medimmune Ltd |
Pirrolobenzodiazepinek és konjugátumaik
|
|
US10751346B2
(en)
|
2012-10-12 |
2020-08-25 |
Medimmune Limited |
Pyrrolobenzodiazepine—anti-PSMA antibody conjugates
|
|
SI2906296T1
(en)
|
2012-10-12 |
2018-06-29 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
CA2885305C
(en)
|
2012-10-12 |
2019-11-12 |
Spirogen Sarl |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
|
WO2014057114A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-anti-psma antibody conjugates
|
|
EP2906297B1
(de)
|
2012-10-12 |
2017-12-06 |
ADC Therapeutics SA |
Pyrrolobenzodiazepin-antikörper-konjugate
|
|
ES2703151T3
(es)
|
2012-10-12 |
2019-03-07 |
Adc Therapeutics Sa |
Conjugados de anticuerpos de pirrolobenzodiazepinas
|
|
BR112015008238A2
(pt)
|
2012-10-12 |
2017-11-28 |
Adc Therapeutics Sarl |
conjugados de pirrolbenzodiazepina-anticorpo anti-cd22
|
|
CA2894961C
(en)
|
2012-12-21 |
2020-09-15 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2014096365A1
(en)
|
2012-12-21 |
2014-06-26 |
Spirogen Sàrl |
Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
|
|
KR102182488B1
(ko)
|
2013-02-25 |
2020-11-24 |
제넨테크, 인크. |
약물 내성 akt 돌연변이체의 검출 및 치료를 위한 방법 및 조성물
|
|
MX364330B
(es)
|
2013-03-13 |
2019-04-23 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de las mismas.
|
|
MX363787B
(es)
|
2013-03-13 |
2019-04-03 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de los mismos.
|
|
JP6444902B2
(ja)
|
2013-03-13 |
2018-12-26 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
ピロロベンゾジアゼピン及びその結合体
|
|
AR095443A1
(es)
|
2013-03-15 |
2015-10-14 |
Fundación Centro Nac De Investig Oncológicas Carlos Iii |
Heterociclos condensados con acción sobre atr
|
|
JP6330028B2
(ja)
|
2013-04-17 |
2018-05-23 |
カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ |
ケトンのエナンチオ選択性還元のためのデザイナー細胞及びエナンチオ濃縮アルコールの効率的製造におけるその使用
|
|
HK1214820A1
(zh)
|
2013-07-03 |
2016-08-05 |
豪夫迈．罗氏有限公司 |
雜芳基吡啶酮和氮雜-吡啶酮酰胺化合物
|
|
US10442836B2
(en)
|
2013-08-12 |
2019-10-15 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1H-benzo[E]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
|
EP3054986B1
(de)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepin-antikörper-konjugate
|
|
US10010624B2
(en)
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054985B1
(de)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepin-antikörper-konjugate
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US9260415B2
(en)
|
2013-12-05 |
2016-02-16 |
Genentech, Inc. |
Heteroaryl pyridone and aza-pyridone compounds with electrophilic functionality
|
|
CN105828840B
(zh)
|
2013-12-16 |
2020-08-04 |
基因泰克公司 |
1-(氯甲基)-2,3-二氢-1H-苯并[e]吲哚二聚体抗体-药物缀合物化合物及使用和治疗方法
|
|
US9133488B2
(en)
|
2013-12-30 |
2015-09-15 |
University Of Alaska Fairbanks |
Synthetic methods and compounds related thereto
|
|
SG11201607334YA
(en)
|
2014-03-13 |
2016-10-28 |
Hoffmann La Roche |
Therapeutic combinations with estrogen receptor modulators
|
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
|
CN106687141A
(zh)
|
2014-09-10 |
2017-05-17 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其缀合物
|
|
WO2016040825A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Anthracycline disulfide intermediates, antibody-drug conjugates and methods
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
MX2017003123A
(es)
|
2014-09-12 |
2017-05-12 |
Genentech Inc |
Anticuerpos y conjugados modificados geneticamente con cisteina.
|
|
JP2017533887A
(ja)
|
2014-09-17 |
2017-11-16 |
ジェネンテック， インコーポレイテッド |
ピロロベンゾジアゼピン類及びその抗体ジスルフィドコンジュゲート
|
|
JP6507234B2
(ja)
|
2014-10-02 |
2019-04-24 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
ブルトンチロシンキナーゼ（ｂｔｋ）によって介入される障害の処置における使用のためのピラゾールカルボキサミド化合物
|
|
US10780096B2
(en)
|
2014-11-25 |
2020-09-22 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US10696953B2
(en)
|
2015-02-10 |
2020-06-30 |
Codexis, Inc. |
Ketoreductase polypeptides for the synthesis of chiral compounds
|
|
JP6957035B2
(ja)
|
2015-04-10 |
2021-11-02 |
トーマス・ジェファーソン・ユニバーシティ |
対象への移植用の免疫原性拡散チャンバおよびその調製方法
|
|
GB201506389D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
DK3341376T3
(da)
|
2015-08-26 |
2021-03-29 |
Fundacion Del Sector Publico Estatal Centro Nac De Investigaciones Oncologicas Carlos Iii F S P Cnio |
Kondenserede tricykliske forbindelser som proteinkinase-inhibitorer
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
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Pyrrolobenzodiazepine Conjugates
|
|
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(en)
|
2016-02-10 |
2016-03-23 |
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|
|
US11241403B2
(en)
|
2016-03-11 |
2022-02-08 |
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|
|
US10973792B2
(en)
|
2019-02-13 |
2021-04-13 |
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|
|
US10973786B2
(en)
|
2016-03-11 |
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R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions
|
|
US10245243B1
(en)
|
2017-12-19 |
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Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use
|
|
US10596129B2
(en)
|
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|
|
US11185518B2
(en)
|
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|
|
US10245242B1
(en)
|
2017-11-22 |
2019-04-02 |
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|
|
US11103470B2
(en)
|
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|
|
US10596131B2
(en)
|
2017-11-22 |
2020-03-24 |
Axcess Global Sciences, Llc |
Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
|
|
US10596130B2
(en)
|
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Axcess Global Sciences, Llc |
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|
|
US10736861B2
(en)
|
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|
|
US10925843B2
(en)
|
2018-04-18 |
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|
|
US11806324B2
(en)
|
2018-04-18 |
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|
|
US12109182B2
(en)
|
2016-04-19 |
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Axcess Global Sciences, Llc |
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|
|
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(en)
|
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2016-06-15 |
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|
|
EP3458069B1
(de)
|
2016-05-18 |
2023-07-05 |
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|
|
US10639378B2
(en)
|
2016-06-06 |
2020-05-05 |
Genentech, Inc. |
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|
|
WO2017223275A1
(en)
|
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2017-12-28 |
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|
|
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(en)
|
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2016-11-30 |
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|
|
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(sr)
|
2017-02-08 |
2021-10-29 |
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|
|
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(en)
|
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|
|
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(hr)
|
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|
|
AU2018255876B2
(en)
|
2017-04-18 |
2020-04-30 |
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|
|
MX2019012464A
(es)
|
2017-04-20 |
2019-12-11 |
Adc Therapeutics Sa |
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|
|
CN117511890A
(zh)
|
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2024-02-06 |
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|
|
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(uk)
|
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|
|
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(hr)
|
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|
|
JP2020534300A
(ja)
|
2017-09-20 |
2020-11-26 |
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|
|
US11202769B2
(en)
|
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Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function
|
|
US12090129B2
(en)
|
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|
|
US12329734B2
(en)
|
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|
|
US11944598B2
(en)
|
2017-12-19 |
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|
|
GB201803342D0
(en)
|
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2018-04-18 |
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|
|
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(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
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|
|
US10980772B2
(en)
|
2018-08-27 |
2021-04-20 |
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|
|
US11241401B2
(en)
|
2020-02-06 |
2022-02-08 |
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|
|
US11129802B2
(en)
|
2018-08-27 |
2021-09-28 |
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Compositions and methods for delivering cannabidiol and ketone bodies
|
|
US11419836B2
(en)
|
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2022-08-23 |
Axcess Global Sciences, Llc |
Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions
|
|
ES2975412T3
(es)
|
2018-06-21 |
2024-07-05 |
Fis Fabbrica Italiana Sintetici Spa |
Proceso enzimático para la preparación de droxidopa
|
|
KR20210139270A
(ko)
|
2019-03-15 |
2021-11-22 |
메드임뮨 리미티드 |
암의 치료에 사용하기 위한 아제티도벤조디아제핀 이량체 및 이를 포함하는 컨쥬게이트
|
|
GB201908128D0
(en)
|
2019-06-07 |
2019-07-24 |
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Pyrrolobenzodiazepine-antibody conjugates
|
|
US11969430B1
(en)
|
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|
|
US11033553B2
(en)
|
2019-06-21 |
2021-06-15 |
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|
|
US11950616B2
(en)
|
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Non-vasoconstricting energy-promoting compositions containing ketone bodies
|
|
US12167993B2
(en)
|
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2024-12-17 |
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|
|
US12186297B2
(en)
|
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|
|
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(en)
|
2021-04-02 |
2023-11-01 |
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|
|
WO2024138128A2
(en)
|
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2024-06-27 |
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|
|
WO2024150146A1
(en)
|
2023-01-12 |
2024-07-18 |
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|