DE69610622D1 - Ein organisches aminenthaltende pranoprofen-augentropfen - Google Patents
Ein organisches aminenthaltende pranoprofen-augentropfenInfo
- Publication number
- DE69610622D1 DE69610622D1 DE69610622T DE69610622T DE69610622D1 DE 69610622 D1 DE69610622 D1 DE 69610622D1 DE 69610622 T DE69610622 T DE 69610622T DE 69610622 T DE69610622 T DE 69610622T DE 69610622 D1 DE69610622 D1 DE 69610622D1
- Authority
- DE
- Germany
- Prior art keywords
- organic amine
- ophthalmic solution
- pranopropen
- eye drops
- amine containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001412 amines Chemical class 0.000 title abstract 5
- 239000003889 eye drop Substances 0.000 title 1
- 229940012356 eye drops Drugs 0.000 title 1
- 229940054534 ophthalmic solution Drugs 0.000 abstract 5
- 239000002997 ophthalmic solution Substances 0.000 abstract 5
- TVQZAMVBTVNYLA-UHFFFAOYSA-N Pranoprofen Chemical compound C1=CC=C2CC3=CC(C(C(O)=O)C)=CC=C3OC2=N1 TVQZAMVBTVNYLA-UHFFFAOYSA-N 0.000 abstract 3
- 229960003101 pranoprofen Drugs 0.000 abstract 3
- JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical compound OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical group OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
- 229960000281 trometamol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP09472395A JP3170619B2 (ja) | 1995-04-20 | 1995-04-20 | 有機アミンを配合したプラノプロフェン点眼液 |
PCT/JP1996/001035 WO1996032941A1 (fr) | 1995-04-20 | 1996-04-16 | Gouttes oculaires de pranoprofene renfermant un amine organique |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69610622D1 true DE69610622D1 (de) | 2000-11-16 |
DE69610622T2 DE69610622T2 (de) | 2001-05-31 |
Family
ID=14118050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69610622T Expired - Fee Related DE69610622T2 (de) | 1995-04-20 | 1996-04-16 | Ein organisches aminenthaltende pranoprofen-augentropfen |
Country Status (10)
Country | Link |
---|---|
US (1) | US6281224B1 (de) |
EP (1) | EP0824916B1 (de) |
JP (1) | JP3170619B2 (de) |
AT (1) | ATE196846T1 (de) |
DE (1) | DE69610622T2 (de) |
DK (1) | DK0824916T3 (de) |
ES (1) | ES2152016T3 (de) |
GR (1) | GR3034705T3 (de) |
PT (1) | PT824916E (de) |
WO (1) | WO1996032941A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6274592B1 (en) | 1997-02-04 | 2001-08-14 | Senju Pharmaceutical Co., Ltd. | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid |
US20020198174A1 (en) * | 2001-05-07 | 2002-12-26 | Allergan Sales, Inc. | Disinfecting and solubilizing steroid compositions |
US6211246B1 (en) * | 1999-06-10 | 2001-04-03 | Mcneil-Ppc, Inc. | Rapidly absorbed liquid compositions |
PT1283042E (pt) * | 2000-05-17 | 2008-11-19 | Senju Pharma Co | Preparação líquida aquosa de pranoprofeno |
JP4707316B2 (ja) * | 2002-10-11 | 2011-06-22 | ロート製薬株式会社 | 水性液状組成物 |
PL1683526T3 (pl) * | 2003-11-14 | 2012-09-28 | Senju Pharma Co | Preparat wodnego roztworu zawierający antybiotyk aminoglikozydowy i bromfenak |
JP4789479B2 (ja) * | 2004-02-23 | 2011-10-12 | ロート製薬株式会社 | プラノプロフェン含有水性組成物 |
JP2005239681A (ja) * | 2004-02-27 | 2005-09-08 | Taisho Pharmaceut Co Ltd | 眼科用剤 |
JP2005239658A (ja) * | 2004-02-27 | 2005-09-08 | Taisho Pharmaceut Co Ltd | 点眼剤 |
JP5434981B2 (ja) * | 2004-02-27 | 2014-03-05 | 大正製薬株式会社 | 点眼剤 |
JP5785353B2 (ja) * | 2004-02-27 | 2015-09-30 | 大正製薬株式会社 | 眼科用剤 |
JP4961671B2 (ja) * | 2004-02-27 | 2012-06-27 | 大正製薬株式会社 | 点眼剤 |
CA2560559C (en) * | 2004-11-05 | 2013-07-02 | Senju Pharmaceutical Co., Ltd. | Aqueous intraocular penetration-promoting eye drop |
US8030349B2 (en) * | 2005-08-02 | 2011-10-04 | Santen Pharmaceutical Co., Ltd. | Method for prevention of degradation of thermally unstable medicament |
JP5252787B2 (ja) * | 2005-08-02 | 2013-07-31 | 参天製薬株式会社 | 熱的に不安定な薬物の分解抑制方法 |
JP5305710B2 (ja) * | 2008-03-31 | 2013-10-02 | 株式会社ニデック | ドルゾラミド塩酸塩点眼液 |
JP5992293B2 (ja) * | 2012-10-31 | 2016-09-14 | 大正製薬株式会社 | 眼科用剤 |
CN105392481B (zh) * | 2013-05-30 | 2018-10-12 | 千寿制药株式会社 | 两性离子性软性隐形眼镜用眼科用组合物 |
KR102493579B1 (ko) * | 2018-01-08 | 2023-01-31 | 삼성전자주식회사 | 카메라를 포함하는 전자 장치 및 전자 장치의 제어 방법 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5195120A (en) * | 1975-02-10 | 1976-08-20 | Tenganekino seizoho | |
JPS5989617A (ja) * | 1982-11-15 | 1984-05-23 | Lion Corp | 点眼液 |
JPS5989616A (ja) * | 1982-11-15 | 1984-05-23 | Lion Corp | 点眼液 |
JPS60184013A (ja) * | 1984-03-01 | 1985-09-19 | Yoshitomi Pharmaceut Ind Ltd | 点眼剤 |
JPS6112617A (ja) * | 1984-06-27 | 1986-01-21 | Lion Corp | 点眼液 |
US4696917A (en) | 1985-08-01 | 1987-09-29 | Lindstrom Richard L | Irrigation solution |
DE3612537C1 (de) | 1986-04-14 | 1987-07-16 | Dispersa Ag | Arzneimittel zur Behandlung von Entzuendungen im Auge |
DE3612538A1 (de) | 1986-04-14 | 1987-10-15 | Dispersa Ag | Stabilisierung von quecksilberhaltigen konservierungsmitteln in augentropfen |
JPS6429170A (en) | 1987-07-24 | 1989-01-31 | Nec Corp | Method and apparatus for recording dot picture |
US5414011A (en) * | 1987-09-11 | 1995-05-09 | Syntex (U.S.A.) Inc. | Preservative system for ophthalmic formulations |
EP0501578A1 (de) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Pyranylphenyl-hydroyalkylnaphthalinsäuren als Inhibitoren der Leuktotrien-Biosynthese |
JPH05186349A (ja) * | 1991-12-30 | 1993-07-27 | Teika Seiyaku Kk | プラノプロフェン点眼剤組成物 |
JPH0717863A (ja) * | 1993-06-30 | 1995-01-20 | Kaken Pharmaceut Co Ltd | プラノプロフェン点眼液 |
JP3021312B2 (ja) * | 1994-03-15 | 2000-03-15 | 千寿製薬株式会社 | プラノプロフェンの安定化方法および安定なプラノプロフェン水性液剤 |
JP3297969B2 (ja) * | 1994-12-26 | 2002-07-02 | ライオン株式会社 | 点眼剤 |
-
1995
- 1995-04-20 JP JP09472395A patent/JP3170619B2/ja not_active Expired - Lifetime
-
1996
- 1996-04-16 ES ES96909378T patent/ES2152016T3/es not_active Expired - Lifetime
- 1996-04-16 PT PT96909378T patent/PT824916E/pt unknown
- 1996-04-16 DE DE69610622T patent/DE69610622T2/de not_active Expired - Fee Related
- 1996-04-16 WO PCT/JP1996/001035 patent/WO1996032941A1/ja active IP Right Grant
- 1996-04-16 EP EP96909378A patent/EP0824916B1/de not_active Expired - Lifetime
- 1996-04-16 DK DK96909378T patent/DK0824916T3/da active
- 1996-04-16 AT AT96909378T patent/ATE196846T1/de not_active IP Right Cessation
- 1996-04-16 US US08/945,198 patent/US6281224B1/en not_active Expired - Fee Related
-
2000
- 2000-10-30 GR GR20000402394T patent/GR3034705T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0824916A1 (de) | 1998-02-25 |
ES2152016T3 (es) | 2001-01-16 |
JP3170619B2 (ja) | 2001-05-28 |
US6281224B1 (en) | 2001-08-28 |
DE69610622T2 (de) | 2001-05-31 |
EP0824916B1 (de) | 2000-10-11 |
JPH08291065A (ja) | 1996-11-05 |
PT824916E (pt) | 2001-01-31 |
DK0824916T3 (da) | 2001-02-05 |
EP0824916A4 (de) | 1999-06-16 |
ATE196846T1 (de) | 2000-10-15 |
GR3034705T3 (en) | 2001-01-31 |
WO1996032941A1 (fr) | 1996-10-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |