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ES2095726T3 - Piperazinas sustituidas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen. - Google Patents

Piperazinas sustituidas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.

Info

Publication number
ES2095726T3
ES2095726T3 ES94401602T ES94401602T ES2095726T3 ES 2095726 T3 ES2095726 T3 ES 2095726T3 ES 94401602 T ES94401602 T ES 94401602T ES 94401602 T ES94401602 T ES 94401602T ES 2095726 T3 ES2095726 T3 ES 2095726T3
Authority
ES
Spain
Prior art keywords
contain
pharmaceutical compositions
preparation procedure
substituted piperazines
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94401602T
Other languages
English (en)
Inventor
Jean-Jacques Godfroid
Aazdine Lamouri
Estera Touboul
Xuan Wang
Pierre Renard
Bruno Pfeiffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2095726T3 publication Critical patent/ES2095726T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

COMPUESTOS DE FORMULA GENERAL (I) EN LA QUE R4, R5 N, Y M SON TALES COMO SE DEFINEN EN LA DESCRIPCION. ESTOS COMPUESTOS ENCUENTRAN SU APLICACION EN TERAPIA EN EL TRATAMIENTO DE DIABETES NO INSULINODEPENDIENTES.
ES94401602T 1993-07-23 1994-07-12 Piperazinas sustituidas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen. Expired - Lifetime ES2095726T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9309088A FR2707984B1 (fr) 1993-07-23 1993-07-23 Nouvelles pipérazines substituées, leur procédé de préparation et les compositions les contenant.

Publications (1)

Publication Number Publication Date
ES2095726T3 true ES2095726T3 (es) 1997-02-16

Family

ID=9449559

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94401602T Expired - Lifetime ES2095726T3 (es) 1993-07-23 1994-07-12 Piperazinas sustituidas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.

Country Status (14)

Country Link
US (2) US5492912A (es)
EP (1) EP0638568B1 (es)
JP (1) JPH0753548A (es)
AT (1) ATE143955T1 (es)
AU (1) AU674759B2 (es)
CA (1) CA2128560A1 (es)
DE (1) DE69400692T2 (es)
DK (1) DK0638568T3 (es)
ES (1) ES2095726T3 (es)
FR (1) FR2707984B1 (es)
GR (1) GR3021770T3 (es)
HK (1) HK56697A (es)
NZ (1) NZ264062A (es)
ZA (1) ZA945423B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883098A (en) * 1993-11-29 1999-03-16 Fujisawa Pharmaceutical Co., Ltd. Piperazine derivatives
FR2757158B1 (fr) 1996-12-18 1999-04-02 Lipha Nouveaux derives d'acide 4-(1-piperazinyl) benzoique, leur procede de preparation et leurs applications therapeutiques
FR2763334A1 (fr) * 1997-05-13 1998-11-20 Lipha Derives anthraniliques
PL372695A1 (en) 2002-06-19 2005-07-25 Solvay Pharmaceuticals Gmbh Medicament for the treatment of diseases requiring inhibition or a reduction in the activity of ph value-regulating bicarbonate transporter proteins
FR2846656B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IL280864B2 (en) 2013-08-09 2024-03-01 Ardelyx Inc Compounds and methods for inhibiting phosphate transport
NZ752196A (en) * 2016-09-21 2022-05-27 Vectus Biosystems Ltd Compositions for the treatment of hypertension and/or fibrosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE485737A (es) * 1947-11-12
CH506548A (de) * 1966-08-10 1971-04-30 Serono Ist Farm Verfahren zur Herstellung von 2-aminsubstituiertem 4,5-Diphenyl-Oxazol
DE3752141T2 (de) * 1986-02-24 1998-03-26 Mitsui Petrochemical Ind Mittel zur behandlung von neuropathie
US5091428A (en) * 1987-04-24 1992-02-25 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
EP0324520A3 (en) * 1988-01-14 1990-08-16 Merck & Co. Inc. Alkyl-piperazinyl-5-6-alkylenepyrimidines

Also Published As

Publication number Publication date
US5500426A (en) 1996-03-19
HK56697A (en) 1997-05-09
EP0638568B1 (fr) 1996-10-09
ATE143955T1 (de) 1996-10-15
DE69400692T2 (de) 1997-05-07
GR3021770T3 (en) 1997-02-28
US5492912A (en) 1996-02-20
CA2128560A1 (fr) 1995-01-24
FR2707984A1 (fr) 1995-01-27
NZ264062A (en) 1995-04-27
DK0638568T3 (es) 1997-03-24
FR2707984B1 (fr) 1995-09-01
AU6860594A (en) 1995-02-02
JPH0753548A (ja) 1995-02-28
EP0638568A1 (fr) 1995-02-15
ZA945423B (en) 1995-03-01
DE69400692D1 (de) 1996-11-14
AU674759B2 (en) 1997-01-09

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