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DE69431120D1 - Verfahren ii - Google Patents

Verfahren ii

Info

Publication number
DE69431120D1
DE69431120D1 DE69431120T DE69431120T DE69431120D1 DE 69431120 D1 DE69431120 D1 DE 69431120D1 DE 69431120 T DE69431120 T DE 69431120T DE 69431120 T DE69431120 T DE 69431120T DE 69431120 D1 DE69431120 D1 DE 69431120D1
Authority
DE
Germany
Prior art keywords
agglomerates
powder
procedure
spheronizing
breath
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69431120T
Other languages
English (en)
Other versions
DE69431120T2 (de
Inventor
Eva Trofast
Magnus Olsson
Claes Ahlneck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9303215A external-priority patent/SE9303215D0/xx
Priority claimed from SE9304270A external-priority patent/SE9304270D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69431120D1 publication Critical patent/DE69431120D1/de
Publication of DE69431120T2 publication Critical patent/DE69431120T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • External Artificial Organs (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Disintegrating Or Milling (AREA)
DE69431120T 1993-10-01 1994-09-29 Verfahren ii Expired - Lifetime DE69431120T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9303215A SE9303215D0 (sv) 1993-10-01 1993-10-01 Process II
SE9304270A SE9304270D0 (sv) 1993-12-22 1993-12-22 Process II
PCT/SE1994/000897 WO1995009616A1 (en) 1993-10-01 1994-09-29 Process ii

Publications (2)

Publication Number Publication Date
DE69431120D1 true DE69431120D1 (de) 2002-09-05
DE69431120T2 DE69431120T2 (de) 2002-11-28

Family

ID=26661852

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69431120T Expired - Lifetime DE69431120T2 (de) 1993-10-01 1994-09-29 Verfahren ii

Country Status (28)

Country Link
US (1) US6371171B1 (de)
EP (1) EP0721332B1 (de)
JP (1) JPH09504225A (de)
KR (1) KR100347497B1 (de)
CN (1) CN1119992C (de)
AT (1) ATE221371T1 (de)
AU (1) AU687896B2 (de)
BR (1) BR9407687A (de)
CA (1) CA2172055C (de)
CZ (1) CZ289394B6 (de)
DE (1) DE69431120T2 (de)
DK (1) DK0721332T3 (de)
EG (1) EG21071A (de)
ES (1) ES2178655T3 (de)
FI (1) FI117318B (de)
HU (1) HU226493B1 (de)
IL (1) IL111081A (de)
IS (1) IS1736B (de)
NO (1) NO316747B1 (de)
NZ (1) NZ274278A (de)
PL (1) PL175596B1 (de)
PT (1) PT721332E (de)
RU (1) RU2170083C2 (de)
SG (1) SG75091A1 (de)
SK (1) SK283554B6 (de)
TW (1) TW374728B (de)
UA (1) UA42736C2 (de)
WO (1) WO1995009616A1 (de)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
DE4425255A1 (de) 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9700134D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5826633A (en) 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
KR100386055B1 (ko) 1997-03-20 2003-06-09 쉐링 코포레이션 분말 응집물의 제조방법
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6182712B1 (en) 1997-07-21 2001-02-06 Inhale Therapeutic Systems Power filling apparatus and methods for their use
DE69924169T2 (de) * 1998-02-27 2006-02-02 Sandvik Intellectual Property Hb Verfahren und Vorrichtung zum tropfenförmigen Aufbringen fliessfähiger Massen auf ein Transportband
US6623760B1 (en) 1999-01-28 2003-09-23 Schering Corporation Method of preparing particles for agglomeration
AU779869B2 (en) 1999-04-13 2005-02-17 Nektar Therapeutics Pulmonary administration of dry powder formulations for treating infertility
ATE461692T1 (de) 1999-10-29 2010-04-15 Novartis Ag Trockenpulverzusammensetzungen mit verbesserter dispersität
WO2002096549A1 (en) * 2001-05-29 2002-12-05 Spheriform Pty Ltd Agglomeration of fine particulate material
SI1458360T1 (sl) 2001-12-19 2011-08-31 Novartis Ag Pulmonalno dajanje aminoglikozidov
PT1699434E (pt) 2003-09-02 2011-05-03 Norton Healthcare Ltd Processo para a prepara??o de um medicamento
EP1701714A2 (de) 2004-01-07 2006-09-20 Nektar Therapeutics Verbesserte zusammensetzungen mit verzögerter freisetzung für die pulmonale verabreichung von insulin
PT1765288E (pt) 2004-06-18 2013-01-29 Novartis Ag Métodos de tratamento de infeções endobrônquicas
CN101239330B (zh) * 2007-02-09 2010-10-27 中国石油化工股份有限公司 微球形催化剂载体的制备方法
KR20100098610A (ko) * 2007-10-25 2010-09-08 노파르티스 아게 단위 투여량의 약물 포장물의 분말 컨디셔닝
US8680263B2 (en) 2008-09-19 2014-03-25 Nektar Therapeutics Carbohydrate-based drug delivery polymers and conjugates thereof
JP5668317B2 (ja) * 2009-04-24 2015-02-12 大正製薬株式会社 プソイドエフェドリン含有製剤粒子
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
MX2022003427A (es) * 2019-09-24 2022-04-18 Chiesi Farm Spa Particulas portadoras novedosas para formulaciones de polvo seco para inhalacion.
CN113695054B (zh) * 2021-09-26 2024-08-30 常州市神工造粒设备有限公司 颗粒钾肥磨圆除粉装置

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
DE2350746C3 (de) * 1973-10-10 1978-08-31 Guenther Papenmeier Gmbh & Co Kg Maschinen- Und Apparatebau, 4930 Detmold Verfahren und Vorrichtungen zur Herstellung von Granulaten aus pulverformigem, körnigem oder teigigem Gut
GB1569611A (en) 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
GB1520247A (en) 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
US4039480A (en) * 1975-03-21 1977-08-02 Reynolds Metals Company Hollow ceramic balls as automotive catalysts supports
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
US4086060A (en) * 1976-10-22 1978-04-25 Jocelyn Dickson Disposable manipulative laboratory device for transferring biological fluids
US4496376A (en) * 1978-01-26 1985-01-29 Litton Systems, Inc. Variable area molecular sieve container having a thermal control system
US4316819A (en) * 1980-08-11 1982-02-23 Uop Inc. Technique to reduce the zeolite molecular sieve solubility in an aqueous system
EP0072046B1 (de) * 1981-07-24 1986-01-15 FISONS plc Inhalierbare Arzneimittel, Verfahren zu deren Herstellung und pharmazeutische Formulierungen diese enthaltend
PL135587B1 (en) * 1982-08-16 1985-11-30 Zabrzanska Fabryka Maszyn Gorniczych "Powen" Centrifugal dewatering screen
US4495308A (en) * 1983-03-04 1985-01-22 Chevron Research Company Two-region spherical catalysts
US4605173A (en) * 1984-04-04 1986-08-12 Edmonds Harvey A Size reduction machine
US4689297A (en) * 1985-03-05 1987-08-25 Miles Laboratories, Inc. Dust free particulate enzyme formulation
US4688610A (en) 1985-03-19 1987-08-25 Spiral Systems Inc. Apparatus for dispensing particulate agglomerating solids
US4655701A (en) * 1986-02-19 1987-04-07 Fuji Paudal Kabushiki Kaisha Granulating apparatus
GB8606762D0 (en) 1986-03-19 1986-04-23 Boots Co Plc Therapeutic agents
US5288500A (en) * 1987-03-13 1994-02-22 Benzon Pharma A/S Oral composition containing particles comprising an active substance
GB8711005D0 (en) * 1987-05-09 1987-06-10 British Petroleum Co Plc Chemical process
ES2044710T3 (es) * 1990-01-29 1994-01-01 Ciba Geigy Ag Procedimiento y dispositivo de dosificacion de un polvo de granulometria fina.
US5547567A (en) * 1990-10-01 1996-08-20 Cps - Chemical Products & Services A/S Apparatus for washing-down serigraphical frames and filterpart for the apparatus
GB9027018D0 (en) 1990-12-12 1991-01-30 Ici Plc Heterocyclic compounds
DE4105984A1 (de) 1991-02-26 1992-08-27 Deutsche Forsch Luft Raumfahrt Verfahren zur aufbereitung pulverfoermiger rohstoffe
US5262172A (en) * 1992-06-19 1993-11-16 Digestive Care Inc. Compositions of gastric acid-resistant microspheres containing buffered bile acids
US5399358A (en) * 1993-11-12 1995-03-21 Edward Mendell Co., Inc. Sustained release formulations for 24 hour release of metroprolol

Also Published As

Publication number Publication date
DE69431120T2 (de) 2002-11-28
CZ94196A3 (en) 1996-06-12
CA2172055A1 (en) 1995-04-13
FI961431A0 (fi) 1996-03-29
EP0721332B1 (de) 2002-07-31
AU687896B2 (en) 1998-03-05
SG75091A1 (en) 2000-09-19
FI117318B (fi) 2006-09-15
HUT74518A (en) 1997-01-28
PL175596B1 (pl) 1999-01-29
HU226493B1 (en) 2009-03-02
IS4214A (is) 1995-04-02
CN1132477A (zh) 1996-10-02
FI961431L (fi) 1996-03-29
NO961291L (no) 1996-03-29
DK0721332T3 (da) 2002-09-02
CA2172055C (en) 2005-11-08
EP0721332A1 (de) 1996-07-17
ES2178655T3 (es) 2003-01-01
NO961291D0 (no) 1996-03-29
NZ274278A (en) 1997-07-27
SK283554B6 (sk) 2003-09-11
US6371171B1 (en) 2002-04-16
PT721332E (pt) 2002-10-31
CZ289394B6 (cs) 2002-01-16
BR9407687A (pt) 1997-02-04
NO316747B1 (no) 2004-04-26
TW374728B (en) 1999-11-21
EG21071A (en) 2000-10-31
ATE221371T1 (de) 2002-08-15
CN1119992C (zh) 2003-09-03
SK39296A3 (en) 1997-06-04
PL313766A1 (en) 1996-07-22
HU9600823D0 (en) 1996-05-28
JPH09504225A (ja) 1997-04-28
AU7826294A (en) 1995-05-01
IS1736B (is) 1999-12-30
KR100347497B1 (ko) 2002-12-26
IL111081A (en) 1998-12-06
UA42736C2 (uk) 2001-11-15
RU2170083C2 (ru) 2001-07-10
IL111081A0 (en) 1994-11-28
WO1995009616A1 (en) 1995-04-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition