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DE69333605D1 - Stabile injizierbare Paclitaxel Lösung - Google Patents

Stabile injizierbare Paclitaxel Lösung

Info

Publication number
DE69333605D1
DE69333605D1 DE69333605T DE69333605T DE69333605D1 DE 69333605 D1 DE69333605 D1 DE 69333605D1 DE 69333605 T DE69333605 T DE 69333605T DE 69333605 T DE69333605 T DE 69333605T DE 69333605 D1 DE69333605 D1 DE 69333605D1
Authority
DE
Germany
Prior art keywords
taxol
solution
paclitaxel solution
stable injectable
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69333605T
Other languages
English (en)
Other versions
DE69333605T2 (de
Inventor
Paul Handreck
Robyn Elliott
Timothy R Prout
Hernita Ewald
David R Carver
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayne Pharma USA Inc
Original Assignee
Mayne Pharma USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25644377&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69333605(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mayne Pharma USA Inc filed Critical Mayne Pharma USA Inc
Publication of DE69333605D1 publication Critical patent/DE69333605D1/de
Application granted granted Critical
Publication of DE69333605T2 publication Critical patent/DE69333605T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69333605T 1992-11-27 1993-11-18 Stabile injizierbare Paclitaxel Lösung Revoked DE69333605T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPL607492 1992-11-27
AUPL607492 1992-11-27
US99550192A 1992-12-22 1992-12-22
US995501 1992-12-22

Publications (2)

Publication Number Publication Date
DE69333605D1 true DE69333605D1 (de) 2004-09-30
DE69333605T2 DE69333605T2 (de) 2005-02-03

Family

ID=25644377

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69333605T Revoked DE69333605T2 (de) 1992-11-27 1993-11-18 Stabile injizierbare Paclitaxel Lösung
DE69320206T Revoked DE69320206T2 (de) 1992-11-27 1993-11-18 Paclitaxel enthaltende injizierbare zusammensetzung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69320206T Revoked DE69320206T2 (de) 1992-11-27 1993-11-18 Paclitaxel enthaltende injizierbare zusammensetzung

Country Status (12)

Country Link
US (7) US5733888A (de)
EP (4) EP0835657B1 (de)
JP (1) JP2880292B2 (de)
AT (2) ATE169216T1 (de)
AU (1) AU5612694A (de)
CA (2) CA2149150C (de)
DE (2) DE69333605T2 (de)
DK (2) DK0835657T3 (de)
ES (2) ES2119996T3 (de)
GR (1) GR3027724T3 (de)
PT (1) PT835657E (de)
WO (2) WO1994012031A1 (de)

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JPH08503945A (ja) 1996-04-30
US20040204479A1 (en) 2004-10-14
EP1500393A1 (de) 2005-01-26
CA2308082A1 (en) 1994-06-09
US6770670B2 (en) 2004-08-03
WO1994012031A1 (en) 1994-06-09
JP2880292B2 (ja) 1999-04-05
GR3027724T3 (en) 1998-11-30
DE69320206T2 (de) 1999-02-11
PT835657E (pt) 2004-11-30
DK0674510T3 (da) 1999-05-10
EP0835657A1 (de) 1998-04-15
ATE169216T1 (de) 1998-08-15
EP0674510B1 (de) 1998-08-05
EP1384474A1 (de) 2004-01-28
EP0674510A1 (de) 1995-10-04
ES2119996T3 (es) 1998-10-16
US5972992A (en) 1999-10-26
DE69333605T2 (de) 2005-02-03
US5733888A (en) 1998-03-31
US5977164A (en) 1999-11-02
US20030065022A1 (en) 2003-04-03
AU5612694A (en) 1994-06-22
EP0674510A4 (de) 1995-08-12
US6140359A (en) 2000-10-31
CA2149150C (en) 2000-08-01
EP0835657B1 (de) 2004-08-25
WO1994012030A1 (en) 1994-06-09
DK0835657T3 (da) 2005-01-10
ES2224200T3 (es) 2005-03-01
ATE274347T1 (de) 2004-09-15
CA2149150A1 (en) 1994-06-09
US6306894B1 (en) 2001-10-23
DE69320206D1 (de) 1998-09-10

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