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DE69317282D1 - Anti-Rezeptor Antikörper gegen den Vitamin B12/transcobalamin II Rezeptor - Google Patents

Anti-Rezeptor Antikörper gegen den Vitamin B12/transcobalamin II Rezeptor

Info

Publication number
DE69317282D1
DE69317282D1 DE69317282T DE69317282T DE69317282D1 DE 69317282 D1 DE69317282 D1 DE 69317282D1 DE 69317282 T DE69317282 T DE 69317282T DE 69317282 T DE69317282 T DE 69317282T DE 69317282 D1 DE69317282 D1 DE 69317282D1
Authority
DE
Germany
Prior art keywords
receptor
vitamin
transcobalamin
blocking agents
growth blocking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69317282T
Other languages
English (en)
Inventor
Alton Morgan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Receptagen Corp
Original Assignee
Receptagen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Receptagen Corp filed Critical Receptagen Corp
Application granted granted Critical
Publication of DE69317282D1 publication Critical patent/DE69317282D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69317282T 1992-05-08 1993-05-07 Anti-Rezeptor Antikörper gegen den Vitamin B12/transcobalamin II Rezeptor Expired - Lifetime DE69317282D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88054092A 1992-05-08 1992-05-08
PCT/US1993/004341 WO1993023557A1 (en) 1992-05-08 1993-05-07 Anti-receptor agents to the vitamin b12/transcobalamin ii receptor

Publications (1)

Publication Number Publication Date
DE69317282D1 true DE69317282D1 (de) 1998-04-09

Family

ID=25376514

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69317282T Expired - Lifetime DE69317282D1 (de) 1992-05-08 1993-05-07 Anti-Rezeptor Antikörper gegen den Vitamin B12/transcobalamin II Rezeptor

Country Status (11)

Country Link
US (1) US5688504A (de)
EP (1) EP0644948B1 (de)
JP (1) JPH07508174A (de)
KR (1) KR950701390A (de)
AT (1) ATE163679T1 (de)
AU (1) AU680822B2 (de)
CA (1) CA2135277C (de)
DE (1) DE69317282D1 (de)
NO (1) NO944247L (de)
NZ (1) NZ252559A (de)
WO (1) WO1993023557A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7416728B2 (en) 1992-05-08 2008-08-26 Kyto Biopharma, Inc. Growth blocking agents
CA2187346C (en) * 1994-04-08 2010-06-29 A. Charles Morgan, Jr. Receptor modulating agents and methods relating thereto
US5840880A (en) * 1994-04-08 1998-11-24 Receptagen Corporation Receptor modulating agents
US5869465A (en) * 1994-04-08 1999-02-09 Receptagen Corporation Methods of receptor modulation and uses therefor
US5739287A (en) * 1994-04-08 1998-04-14 University Of Washington Biotinylated cobalamins
EP0783526B1 (de) * 1994-09-13 2006-03-01 Kyto Biopharma, Inc. Wachstumsinhibierende agenzien gegen vitamin b12 bindungsstellen von transcobalamin-ii
AU7718296A (en) * 1995-10-19 1997-05-07 Receptagen Corporation Vitamin B12 receptor modulating agents and methods related thereto
US20020102258A1 (en) * 1997-05-12 2002-08-01 Smithkline Beecham Corporation Human tumor necrosis factor receptor-like 2 (TR2) antibodies
EP1009431A4 (de) * 1997-05-12 2000-09-27 Smithkline Beckman Corp Antikörper gegen den menschlichen tumornekrosefaktor-rezeptor des typs 2 (tr2)
US6410245B1 (en) * 1998-04-01 2002-06-25 Affymax, Inc. Compositions and methods for detecting ligand-dependent nuclear receptor and coactivator interactions
GB9820473D0 (en) * 1998-09-18 1998-11-11 Axis Biochemicals Asa Assay
US6492497B1 (en) * 1999-04-30 2002-12-10 Cambridge Antibody Technology Limited Specific binding members for TGFbeta1
EP1372717A2 (de) 2001-03-23 2004-01-02 Aphton Corporation Kombinationsbehandlung von pankreaskrebs
GB0109925D0 (en) * 2001-04-23 2001-06-13 Axis Shield Asa Method
US20090191232A1 (en) * 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
US20040047917A1 (en) * 2002-09-06 2004-03-11 Stephen Wilson Drug delivery and targeting with vitamin B12 conjugates
DK1794586T3 (da) 2004-09-22 2013-05-13 Cancer Advances Inc Monoklonale antistoffer til progastrin
AU2007208340B2 (en) * 2006-01-23 2012-11-01 Joseph P. Errico Methods and compositions of targeted drug development
JP5524610B2 (ja) 2006-04-07 2014-06-18 ザ リサーチ ファウンデーション オブ ステイト ユニバーシティー オブ ニューヨーク トランスコバラミン受容体ポリペプチド、核酸およびその調節因子、ならびに細胞の増殖の調節ならびにガンおよびコバラミン欠損症の処置に使用する関連方法
US9044461B2 (en) 2006-04-07 2015-06-02 The Research Foundation Of State University Of New York Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency
US9120858B2 (en) 2011-07-22 2015-09-01 The Research Foundation Of State University Of New York Antibodies to the B12-transcobalamin receptor
CN111050789A (zh) 2017-06-15 2020-04-21 癌症进展有限公司 用于诱导针对肿瘤和癌症的体液免疫和细胞免疫的组合物和方法
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4332785A (en) * 1980-04-09 1982-06-01 University Patents, Inc. Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein
JPS633262A (ja) * 1986-06-24 1988-01-08 Toshiba Corp 網状赤血球の分析方法及び装置

Also Published As

Publication number Publication date
NZ252559A (en) 1996-10-28
AU4239193A (en) 1993-12-13
CA2135277A1 (en) 1993-11-25
CA2135277C (en) 2001-04-24
EP0644948B1 (de) 1998-03-04
KR950701390A (ko) 1995-03-23
EP0644948A1 (de) 1995-03-29
JPH07508174A (ja) 1995-09-14
NO944247D0 (no) 1994-11-07
AU680822B2 (en) 1997-08-14
US5688504A (en) 1997-11-18
WO1993023557A1 (en) 1993-11-25
ATE163679T1 (de) 1998-03-15
NO944247L (no) 1995-01-09

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Legal Events

Date Code Title Description
8332 No legal effect for de