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DE69123357D1 - Einmalinhalator - Google Patents

Einmalinhalator

Info

Publication number
DE69123357D1
DE69123357D1 DE69123357T DE69123357T DE69123357D1 DE 69123357 D1 DE69123357 D1 DE 69123357D1 DE 69123357 T DE69123357 T DE 69123357T DE 69123357 T DE69123357 T DE 69123357T DE 69123357 D1 DE69123357 D1 DE 69123357D1
Authority
DE
Germany
Prior art keywords
compartment
powder
housing
air
end forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69123357T
Other languages
English (en)
Other versions
DE69123357T2 (de
Inventor
Goeran Kaellstrand
Per-Gunnar Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra AB filed Critical Astra AB
Application granted granted Critical
Publication of DE69123357D1 publication Critical patent/DE69123357D1/de
Publication of DE69123357T2 publication Critical patent/DE69123357T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043—Non-destructive separation of the package, e.g. peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Steroid Compounds (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Ink Jet (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Semiconductor Lasers (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
  • Seasonings (AREA)
  • Pyridine Compounds (AREA)
DE69123357T 1990-09-12 1991-09-10 Einmalinhalator Expired - Lifetime DE69123357T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9002895A SE9002895D0 (sv) 1990-09-12 1990-09-12 Inhalation devices for dispensing powders i
PCT/SE1991/000601 WO1992004069A1 (en) 1990-09-12 1991-09-10 Disposable inhaler

Publications (2)

Publication Number Publication Date
DE69123357D1 true DE69123357D1 (de) 1997-01-09
DE69123357T2 DE69123357T2 (de) 1997-03-27

Family

ID=20380330

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69123357T Expired - Lifetime DE69123357T2 (de) 1990-09-12 1991-09-10 Einmalinhalator

Country Status (25)

Country Link
US (1) US5660169A (de)
EP (1) EP0548166B1 (de)
JP (1) JP2894834B2 (de)
KR (1) KR0169749B1 (de)
AT (1) ATE145562T1 (de)
AU (1) AU650058B2 (de)
BR (1) BR9106837A (de)
CA (1) CA2090694C (de)
CZ (1) CZ280659B6 (de)
DE (1) DE69123357T2 (de)
DK (1) DK0548166T3 (de)
EE (1) EE02959B1 (de)
ES (1) ES2094819T3 (de)
FI (1) FI105776B (de)
GR (1) GR3022518T3 (de)
HU (1) HU213804B (de)
LT (1) LT3718B (de)
LV (1) LV10206B (de)
NO (1) NO304875B1 (de)
NZ (1) NZ239707A (de)
SE (1) SE9002895D0 (de)
SG (1) SG47055A1 (de)
SK (1) SK278867B6 (de)
UA (1) UA26276C2 (de)
WO (1) WO1992004069A1 (de)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
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HU213221B (en) 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
YU48707B (sh) * 1990-03-02 1999-07-28 Glaxo Group Limited Aparat za inhaliranje - inhalator
EP0558879B1 (de) * 1992-03-04 1997-05-14 Astra Aktiebolag Wegwerfinhalator
HU216427B (hu) * 1992-09-11 1999-06-28 Glaxo Group Ltd. Inhalálókészülék
SE9203570D0 (sv) * 1992-11-27 1992-11-27 Astra Ab Inhaler for multiple use
US6250300B1 (en) 1992-12-11 2001-06-26 Ab Astra System for dispensing pharmaceutically active compounds
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US6165976A (en) 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
ATE236617T1 (de) 1994-12-22 2003-04-15 Astrazeneca Ab Aerosol-arzneiformulierungen
DK0806945T3 (da) 1994-12-22 2003-08-04 Astrazeneca Ab Terapeutisk præparat til inhalering, indeholdende parathyroideahormon, PTH
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
SE9502800D0 (sv) * 1995-08-10 1995-08-10 Astra Ab Disposable inhaler
SE9502799D0 (sv) * 1995-08-10 1995-08-10 Astra Ab Device in inhalers
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device
SE9700423D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Disposable inhaler
CA2212430A1 (en) * 1997-08-07 1999-02-07 George Volgyesi Inhalation device
SE9800897D0 (sv) 1998-03-17 1998-03-17 Astra Ab Inhalation device
GB9810126D0 (de) * 1998-05-13 1998-07-08 Glaxo Group Ltd
US6223744B1 (en) 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
GB9909357D0 (en) * 1999-04-24 1999-06-16 Glaxo Group Ltd Medicament carrier
GB9909354D0 (en) 1999-04-24 1999-06-16 Glaxo Group Ltd Medicament carrier
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DE19942791A1 (de) * 1999-09-08 2001-03-15 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
MXPA02008403A (es) 2000-02-28 2004-09-27 Vectura Ltd Mejoras en o relacionadas con el suministro de farmacos por via oral.
US6948494B1 (en) * 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
AU2001283546A1 (en) * 2000-08-14 2002-02-25 Advanced Inhalation Research, Inc. Inhalation device and method
SE517227C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
SE0101825D0 (sv) 2001-05-22 2001-05-22 Astrazeneca Ab An Inhalation device
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
GR1004350B (el) 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
US6941947B2 (en) * 2002-12-18 2005-09-13 Quadrant Technologies Limited Unit dose dry powder inhaler
EP1488819A1 (de) 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Trockenpulverinhalator und Verfahren zur pulmonalen Inhalation von Trockenpulver
ES2644717T3 (es) * 2003-10-21 2017-11-30 Direct-Haler A/S Inhalador
DE10356925B4 (de) * 2003-12-05 2006-05-11 Lts Lohmann Therapie-Systeme Ag Inhalator für basische pharmazeutische Wirkstoffe sowie Verfahren für dessen Herstellung
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
DE102004022796A1 (de) * 2004-05-08 2005-12-01 Arndt Muhle Inhalationsgerät
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
KR20150039211A (ko) 2004-08-23 2015-04-09 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
JP2006130143A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
US20070012316A1 (en) * 2005-07-14 2007-01-18 Joann Truza Disposable compact rescue inhaler
WO2007033372A2 (en) 2005-09-14 2007-03-22 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
MX360812B (es) 2006-02-22 2018-11-16 Mannkind Corp Un método para mejorar las propiedades farmacéuticas de micropartículas que contienen dicetopiperazina y un agente activo.
PT103481B (pt) * 2006-05-16 2008-08-01 Hovione Farmaciencia S A Inalador de uso simples e método de inalação
JP2009543658A (ja) * 2006-07-14 2009-12-10 アストラゼネカ・アクチエボラーグ 乾燥粉末状の薬を投与するための吸入装置及び配送装置
WO2008101992A1 (en) * 2007-02-21 2008-08-28 Novo Nordisk A/S Aerosol generating device with air flow control
US8496002B2 (en) * 2007-06-12 2013-07-30 Civitas Therapeutics, Inc. Powder inhaler devices
US20090084379A1 (en) * 2007-10-02 2009-04-02 Baxter International Inc. Dry powder inhaler
JP5114158B2 (ja) * 2007-10-19 2013-01-09 株式会社カナエ ブリスターパック
RU2484852C2 (ru) 2007-12-20 2013-06-20 Астразенека Аб Устройство и способ дезагрегации порошкообразного средства 854
DE102008023376A1 (de) 2008-05-13 2009-11-19 Alfred Von Schuckmann Spender für in einer gesonderten Verpackung enthaltenen, pulverförmigen Massen
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX395141B (es) 2008-06-13 2025-03-24 Mannkind Corp Inhalador de polvo y sistema para suministro de farmaco.
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
TWI547487B (zh) 2009-06-12 2016-09-01 曼凱公司 具限定比表面積之二酮基哌微粒子
US9211383B2 (en) * 2009-07-01 2015-12-15 Astrazeneca Ab Dispenser and method for entraining powder in an airflow
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
RU2569776C2 (ru) 2011-04-01 2015-11-27 Маннкайнд Корпорейшн Блистерная упаковка для фармацевтических картриджей
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EP2747815B1 (de) 2011-09-07 2017-11-29 Concentrx Pharmaceuticals, Inc. Trockenpulverinhalator
US11027156B2 (en) 2011-10-21 2021-06-08 Honeywell International Inc. Emergency filter system for ventilated hood
US10004925B2 (en) 2011-10-21 2018-06-26 Honeywell International Inc. Emergency filter system for encapsulated suit
AU2012328885B2 (en) 2011-10-24 2017-08-31 Mannkind Corporation Methods and compositions for treating pain
BR112015000529B1 (pt) 2012-07-12 2022-01-11 Mannkind Corporation Inalador de pó seco
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
AT513144B1 (de) * 2013-01-09 2014-02-15 Steyr Mannlicher Gmbh Feuerwaffe und Gehäuse hiefür
ES2928365T3 (es) 2013-03-15 2022-11-17 Mannkind Corp Composiciones de dicetopiperazina microcristalina, métodos de preparación y uso del mismo
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
US10238820B2 (en) 2014-01-08 2019-03-26 Seroton, Inc. Dry-powder inhalation device
US11491288B2 (en) 2014-01-08 2022-11-08 Seroton, Inc. Dispenser for dry-powder inhalation devices
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
EP2929913B1 (de) 2014-04-07 2016-04-06 Honeywell International Inc. Integrierte Luftrückverteilung in belüftetem Anzug
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
DE102014017409B4 (de) * 2014-11-26 2016-06-09 Klaus Dieter Beller Einzeldosis-Pulverinhalator und Verfahren zu dessen Herstellung
EP3600504B1 (de) 2017-03-28 2023-07-12 Concentrx Pharmaceuticals, Inc. Vorrichtung zur ausgabe von trockenpulvermedikamenten
CA3096576A1 (en) * 2017-09-28 2019-04-04 Iconovo Ab A dry powder inhaler with means for enhancing dispersion

Family Cites Families (10)

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US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
US4265236A (en) * 1980-03-31 1981-05-05 Pacella Angelo M Portable inhalator device
NO166268C (no) * 1985-07-30 1991-07-03 Glaxo Group Ltd Innretning for administrering av medikamenter til pasienter.
AT384552B (de) * 1985-08-01 1987-12-10 Hurka Wilhelm Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
SE453566B (sv) * 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4817800A (en) * 1987-05-20 1989-04-04 Surgikos, Inc. Fluid injection system cassette and fluid packaging methods
CA1329526C (en) * 1987-08-20 1994-05-17 Hiroshi Ikura Powdery medicine applicator device
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
GB8914223D0 (en) * 1989-06-21 1989-08-09 Fisons Plc Medicament container
US5042472A (en) * 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device

Also Published As

Publication number Publication date
US5660169A (en) 1997-08-26
KR930702038A (ko) 1993-09-08
CZ30893A3 (en) 1993-11-17
JP2894834B2 (ja) 1999-05-24
CZ280659B6 (cs) 1996-03-13
DE69123357T2 (de) 1997-03-27
HU9300725D0 (en) 1993-09-28
HUT67168A (en) 1995-02-28
EE02959B1 (et) 1997-02-17
LTIP1716A (en) 1995-07-25
JPH06500934A (ja) 1994-01-27
EP0548166A1 (de) 1993-06-30
ATE145562T1 (de) 1996-12-15
HU213804B (en) 1997-10-28
DK0548166T3 (da) 1997-04-14
FI105776B (fi) 2000-10-13
GR3022518T3 (en) 1997-05-31
CA2090694A1 (en) 1992-03-13
HK1001555A1 (en) 1998-06-26
LT3718B (en) 1996-02-26
AU8512691A (en) 1992-03-30
NO304875B1 (no) 1999-03-01
BR9106837A (pt) 1993-06-15
NZ239707A (en) 1994-06-27
SE9002895D0 (sv) 1990-09-12
SG47055A1 (en) 1998-03-20
FI931094L (fi) 1993-03-11
NO930784L (no) 1993-03-03
SK278867B6 (sk) 1998-04-08
AU650058B2 (en) 1994-06-09
EP0548166B1 (de) 1996-11-27
KR0169749B1 (ko) 1999-01-15
UA26276C2 (uk) 1999-07-19
FI931094A0 (fi) 1993-03-11
LV10206B (en) 1995-08-20
LV10206A (lv) 1994-10-20
NO930784D0 (no) 1993-03-03
ES2094819T3 (es) 1997-02-01
CA2090694C (en) 2003-01-28
WO1992004069A1 (en) 1992-03-19
SK15493A3 (en) 1994-02-02

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Legal Events

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