DE69102415D1 - Ester der 10-(1-Hydroxy-äthyl)-11-oxo-1-Azatricyclo[7.2.0.0(3,8)]undec-2-ene-2-Carbonsäure und deren Derivate und Verfahren zu ihrer Herstellung. - Google Patents

Ester der 10-(1-Hydroxy-äthyl)-11-oxo-1-Azatricyclo[7.2.0.0(3,8)]undec-2-ene-2-Carbonsäure und deren Derivate und Verfahren zu ihrer Herstellung.

Info

Publication number: DE69102415D1
Authority: DE; Germany
Prior art keywords: azatricyclo; undec; ene; oxo; hydroxyethyl
Prior art date: 1990-08-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69102415T

Other languages

English (en)

Other versions

DE69102415T2 (de

Inventor

Alcide Perboni

Tino Rossi

Giovanni Gaviraghi

Antonella Ursini

Giorgio Tarzia

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

GlaxoSmithKline SpA

Original Assignee

Glaxo SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-21

Filing date

1991-08-20

Publication date

1994-07-14

1990-08-21 Priority claimed from GB909018330A external-priority patent/GB9018330D0/en

1991-03-07 Priority claimed from GB919104770A external-priority patent/GB9104770D0/en

1991-08-20 Application filed by Glaxo SpA filed Critical Glaxo SpA

1994-07-14 Application granted granted Critical

1994-07-14 Publication of DE69102415D1 publication Critical patent/DE69102415D1/de

1994-10-13 Publication of DE69102415T2 publication Critical patent/DE69102415T2/de

2011-08-21 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heat Sensitive Colour Forming Recording (AREA)
Plural Heterocyclic Compounds (AREA)

DE69102415T 1990-08-21 1991-08-20 Ester der 10-(1-Hydroxy-äthyl)-11-oxo-1-Azatricyclo[7.2.0.0(3,8)]undec-2-ene-2-Carbonsäure und deren Derivate und Verfahren zu ihrer Herstellung. Expired - Fee Related DE69102415T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB909018330A GB9018330D0 (en)	1990-08-21	1990-08-21	Heterocyclic compounds
GB919104770A GB9104770D0 (en)	1991-03-07	1991-03-07	Heterocyclic compounds
PCT/EP1991/001589 WO1992003437A1 (en)	1990-08-21	1991-08-20	10(1-hydroxyethyl)-11-oxo-1-azatricyclo[7.2.0.0.3.8]undec-2-ene-2-carboxylic acid esters and a process for preparing thereof

Publications (2)

Publication Number	Publication Date
DE69102415D1 true DE69102415D1 (de)	1994-07-14
DE69102415T2 DE69102415T2 (de)	1994-10-13

Family

ID=26297540

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69102415T Expired - Fee Related DE69102415T2 (de)	1990-08-21	1991-08-20	Ester der 10-(1-Hydroxy-äthyl)-11-oxo-1-Azatricyclo[7.2.0.0(3,8)]undec-2-ene-2-Carbonsäure und deren Derivate und Verfahren zu ihrer Herstellung.

Country Status (32)

Country	Link
US (1)	US5587374A (de)
EP (1)	EP0495953B1 (de)
JP (2)	JP3151215B2 (de)
KR (1)	KR0169147B1 (de)
CN (1)	CN1030917C (de)
AP (1)	AP238A (de)
AT (1)	ATE106887T1 (de)
AU (1)	AU647178B2 (de)
CA (1)	CA2067741C (de)
CY (1)	CY2037A (de)
CZ (1)	CZ280942B6 (de)
DE (1)	DE69102415T2 (de)
DK (1)	DK0495953T3 (de)
ES (1)	ES2054502T3 (de)
FI (1)	FI97136C (de)
HK (1)	HK19495A (de)
HR (1)	HRP940556B1 (de)
HU (2)	HUT61024A (de)
IE (1)	IE66122B1 (de)
IL (1)	IL99248A (de)
MX (1)	MX9100743A (de)
MY (1)	MY106997A (de)
NO (1)	NO300176B1 (de)
NZ (1)	NZ239474A (de)
OA (1)	OA09578A (de)
PL (1)	PL169425B1 (de)
PT (1)	PT98729B (de)
SG (1)	SG169494G (de)
SI (1)	SI9111427B (de)
SK (1)	SK121392A3 (de)
WO (1)	WO1992003437A1 (de)
YU (1)	YU48079B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9104838D0 (en) *	1991-03-07	1991-04-17	Glaxo Spa	Heterocyclic compounds
AP294A (en) *	1992-08-31	1993-12-28	Glaxo Spa	"10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8) undec-2-ene-2-carboxylic acid derivatives".
GB9218781D0 (en) *	1992-09-04	1992-10-21	Glaxo Spa	Heterocyclic derivatives
IN188720B (de) *	1997-11-06	2002-11-02	Panacea Biotec Ltd
KR100945706B1 (ko) *	2001-11-05	2010-03-05	다이닛본 스미토모 세이야꾸 가부시끼가이샤	신규 카르바페넴 화합물
WO2004089954A1 (ja) *	2003-04-08	2004-10-21	Sumitomo Pharmaceuticals Co., Ltd.	新規なカルバペネム化合物
EP1785426A4 (de) *	2004-09-03	2008-02-20	Dainippon Sumitomo Pharma Co	Neue carbapenemverbindung
JPWO2006103999A1 (ja) *	2005-03-25	2008-09-04	大日本住友製薬株式会社	新規なカルバペネム化合物
EP2085084A1 (de)	2008-01-29	2009-08-05	LEK Pharmaceuticals D.D.	Verwendung eines Hemmers von Beta-Lactamasen und dessen Kombination mit Beta-Lactam-Antibiotika
EP2135871A1 (de) *	2008-06-18	2009-12-23	LEK Pharmaceuticals D.D.	Neuartige Trinemantibiotika und Hemmer von Beta-Lactamasen
EP3621609B1 (de)	2017-05-08	2022-07-27	GlaxoSmithKline Intellectual Property Development Limited	Sanfetrinem oder ein salz oder ester davon zur verwendung bei der behandlung von mykobakterieninfektionen

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1433131A (en) *	1972-03-13	1976-04-22	Astra Laekemedel Ab	Penicillins
GB1425571A (en) *	1972-03-13	1976-02-18	Astra Laekemedel Ab	Penicillins and cephaosporins
DE2811514A1 (de) *	1977-03-19	1978-09-21	Beecham Group Ltd	Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
US4374849A (en) *	1981-09-14	1983-02-22	Merck & Co., Inc.	6-Amidocyclonocardicins
US4374848A (en) *	1981-09-14	1983-02-22	Merck & Co., Inc.	6-(1-Hydroxyethyl)cyclonocardicin
CZ435990A3 (cs) *	1989-09-08	1999-11-17	Glaxo S.P.A.	Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
AU636913B2 (en) *	1989-10-11	1993-05-13	Takeda Chemical Industries Ltd.	Tricyclic carbapenem compounds
GB9104838D0 (en) *	1991-03-07	1991-04-17	Glaxo Spa	Heterocyclic compounds
GB9104832D0 (en) *	1991-03-07	1991-04-17	Glaxo Spa	Heterocyclic compounds

1991
- 1991-08-20 IE IE294491A patent/IE66122B1/en not_active IP Right Cessation
- 1991-08-20 AP APAP/P/1991/000320A patent/AP238A/en active
- 1991-08-20 HU HU921303A patent/HUT61024A/hu unknown
- 1991-08-20 PT PT98729A patent/PT98729B/pt not_active IP Right Cessation
- 1991-08-20 IL IL9924891A patent/IL99248A/en not_active IP Right Cessation
- 1991-08-20 EP EP91914351A patent/EP0495953B1/de not_active Expired - Lifetime
- 1991-08-20 ES ES91914351T patent/ES2054502T3/es not_active Expired - Lifetime
- 1991-08-20 AT AT91914351T patent/ATE106887T1/de not_active IP Right Cessation
- 1991-08-20 DK DK91914351.1T patent/DK0495953T3/da active
- 1991-08-20 CN CN91109093A patent/CN1030917C/zh not_active Expired - Fee Related
- 1991-08-20 SK SK1213-92A patent/SK121392A3/sk unknown
- 1991-08-20 JP JP51366091A patent/JP3151215B2/ja not_active Expired - Fee Related
- 1991-08-20 YU YU142791A patent/YU48079B/sh unknown
- 1991-08-20 SI SI9111427A patent/SI9111427B/sl unknown
- 1991-08-20 WO PCT/EP1991/001589 patent/WO1992003437A1/en active IP Right Grant
- 1991-08-20 MX MX9100743A patent/MX9100743A/es unknown
- 1991-08-20 PL PL91294573A patent/PL169425B1/pl unknown
- 1991-08-20 CZ CS921213A patent/CZ280942B6/cs not_active IP Right Cessation
- 1991-08-20 MY MYPI91001514A patent/MY106997A/en unknown
- 1991-08-20 NZ NZ239474A patent/NZ239474A/en unknown
- 1991-08-20 DE DE69102415T patent/DE69102415T2/de not_active Expired - Fee Related
- 1991-08-20 AU AU84212/91A patent/AU647178B2/en not_active Ceased
- 1991-08-20 CA CA002067741A patent/CA2067741C/en not_active Expired - Fee Related
1992
- 1992-04-13 OA OA60190A patent/OA09578A/en unknown
- 1992-04-15 NO NO921521A patent/NO300176B1/no unknown
- 1992-04-16 FI FI921717A patent/FI97136C/fi active
- 1992-04-20 KR KR1019920700916A patent/KR0169147B1/ko not_active Expired - Fee Related
1994
- 1994-09-16 HR HR940556A patent/HRP940556B1/xx not_active IP Right Cessation
- 1994-12-01 SG SG169494A patent/SG169494G/en unknown
1995
- 1995-02-09 HK HK19495A patent/HK19495A/xx not_active IP Right Cessation
- 1995-02-14 US US08/388,515 patent/US5587374A/en not_active Expired - Fee Related
- 1995-06-27 HU HU95P/P00455P patent/HU211584A9/hu unknown
1998
- 1998-02-20 CY CY203798A patent/CY2037A/xx unknown
2000
- 2000-05-17 JP JP2000144232A patent/JP3461786B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
SI9111427B (sl)	2000-10-31
FI97136C (fi)	1996-10-25
FI97136B (fi)	1996-07-15
EP0495953B1 (de)	1994-06-08
JP3461786B2 (ja)	2003-10-27
HK19495A (en)	1995-02-17
HRP940556B1 (en)	2000-06-30
PL169425B1 (pl)	1996-07-31
US5587374A (en)	1996-12-24
KR0169147B1 (en)	1999-01-15
SG169494G (en)	1995-04-28
NO300176B1 (no)	1997-04-21
PT98729A (pt)	1992-07-31
AP238A (en)	1993-02-04
KR920702361A (ko)	1992-09-03
SK278470B6 (en)	1997-06-04
SI9111427A (en)	1996-12-31
CA2067741A1 (en)	1992-02-22
DK0495953T3 (da)	1994-07-18
ES2054502T3 (es)	1994-08-01
WO1992003437A1 (en)	1992-03-05
JP3151215B2 (ja)	2001-04-03
IL99248A0 (en)	1992-07-15
HRP940556A2 (en)	1996-06-30
FI921717A0 (fi)	1992-04-16
HUT61024A (en)	1992-11-30
CN1060094A (zh)	1992-04-08
MX9100743A (es)	1992-04-01
PT98729B (pt)	1999-01-29
AP9100320A0 (en)	1991-10-31
CY2037A (en)	1998-02-20
AU8421291A (en)	1992-03-17
HU9201303D0 (en)	1992-07-28
CZ121392A3 (en)	1993-04-14
OA09578A (en)	1993-01-31
CA2067741C (en)	2002-01-01
DE69102415T2 (de)	1994-10-13
YU142791A (sh)	1994-01-20
IE66122B1 (en)	1995-12-13
IL99248A (en)	1996-01-31
JP2000351730A (ja)	2000-12-19
EP0495953A1 (de)	1992-07-29
NO921521D0 (no)	1992-04-15
FI921717L (fi)	1992-04-16
MY106997A (en)	1995-08-30
NZ239474A (en)	1994-06-27
IE912944A1 (en)	1992-02-26
CZ280942B6 (cs)	1996-05-15
YU48079B (sh)	1997-01-08
SK121392A3 (en)	1997-06-04
CN1030917C (zh)	1996-02-07
NO921521L (no)	1992-06-22
JPH05502044A (ja)	1993-04-15
AU647178B2 (en)	1994-03-17
ATE106887T1 (de)	1994-06-15
HU211584A9 (en)	1995-12-28

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Legal Events

Date	Code	Title	Description
1995-07-06	8364	No opposition during term of opposition
2006-10-26	8328	Change in the person/name/address of the agent	Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN
2007-06-28	8339	Ceased/non-payment of the annual fee