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DE69028312D1 - Verfahren zur überwachung der reagenzförderung in einem abtastspektrophotometer - Google Patents

Verfahren zur überwachung der reagenzförderung in einem abtastspektrophotometer

Info

Publication number
DE69028312D1
DE69028312D1 DE69028312T DE69028312T DE69028312D1 DE 69028312 D1 DE69028312 D1 DE 69028312D1 DE 69028312 T DE69028312 T DE 69028312T DE 69028312 T DE69028312 T DE 69028312T DE 69028312 D1 DE69028312 D1 DE 69028312D1
Authority
DE
Germany
Prior art keywords
reagent
dye
concentration
reaction mixture
spectral region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69028312T
Other languages
English (en)
Other versions
DE69028312T2 (de
Inventor
Richard Driscoll
Timothy Fischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tcoag Ireland Ltd Dublin Ie
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE69028312D1 publication Critical patent/DE69028312D1/de
Application granted granted Critical
Publication of DE69028312T2 publication Critical patent/DE69028312T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Plasma & Fusion (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
DE69028312T 1989-12-01 1990-12-03 Verfahren zur überwachung der reagenzförderung in einem abtastspektrophotometer Expired - Lifetime DE69028312T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/443,953 US5068181A (en) 1989-12-01 1989-12-01 Method of monitoring reagent delivery in a scanning spectrophotometer
PCT/US1990/007068 WO1991008461A1 (en) 1989-12-01 1990-12-03 Method of monitoring reagent delivery in a scanning spectrophotometer

Publications (2)

Publication Number Publication Date
DE69028312D1 true DE69028312D1 (de) 1996-10-02
DE69028312T2 DE69028312T2 (de) 1997-01-16

Family

ID=23762872

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69028312T Expired - Lifetime DE69028312T2 (de) 1989-12-01 1990-12-03 Verfahren zur überwachung der reagenzförderung in einem abtastspektrophotometer

Country Status (14)

Country Link
US (1) US5068181A (de)
EP (1) EP0502983B1 (de)
JP (1) JP2902108B2 (de)
KR (1) KR100210736B1 (de)
AT (1) ATE142018T1 (de)
AU (2) AU655577B2 (de)
CA (1) CA2069887C (de)
DE (1) DE69028312T2 (de)
DK (1) DK0502983T3 (de)
ES (1) ES2095310T3 (de)
FI (1) FI101575B1 (de)
GR (1) GR3021261T3 (de)
IE (1) IE75698B1 (de)
WO (1) WO1991008461A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646046A (en) * 1989-12-01 1997-07-08 Akzo Nobel N.V. Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
AU1414292A (en) * 1991-02-15 1992-09-15 Formulogics, Inc. Determination of contaminants
US5580744A (en) * 1992-04-27 1996-12-03 Avocet Medical, Inc. Test article and method for performing blood coagulation assays
US5344036A (en) * 1992-06-04 1994-09-06 Akzo N.V. Container system
US5447838A (en) * 1992-08-05 1995-09-05 Hybritech Incorporated Protein-dye conjugate for confirmation of correct dilution of calibrators
US5919707A (en) * 1994-12-22 1999-07-06 Nalco Chemical Company Monitoring of rolling oil emulsions
US6521182B1 (en) * 1998-07-20 2003-02-18 Lifescan, Inc. Fluidic device for medical diagnostics
US6830934B1 (en) * 1999-06-15 2004-12-14 Lifescan, Inc. Microdroplet dispensing for a medical diagnostic device
DE10257716B4 (de) 2002-12-11 2005-12-29 Institut für Textilchemie der Deutschen Institute für Textil- und Faserforschung Stuttgart Optischer Sensor zur Bestimmung von Farbstoffkonzentrationen in flüssigen Medien und Verfahren zu dessen Betrieb
US7283245B2 (en) * 2004-01-20 2007-10-16 General Electric Company Handheld device with a disposable element for chemical analysis of multiple analytes
US20060001551A1 (en) * 2004-06-30 2006-01-05 Ulrich Kraft Analyte monitoring system with wireless alarm
US20060000709A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Methods for modulation of flow in a flow pathway
US20060002817A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Flow modulation devices
US20060000710A1 (en) 2004-06-30 2006-01-05 Klaus Peter Weidenhaupt Fluid handling methods
CA2719012C (en) 2008-03-21 2013-07-09 Abbott Point Of Care, Inc. Method and apparatus for detecting and counting platelets individually and in aggregate clumps
EP2265946B1 (de) 2008-03-21 2012-08-01 Abbott Point Of Care, Inc. Verfahren und vorrichtung zur bestimmung des hämatokrit einer blutprobe unter nutzung der intrinsischen pigmentierung von in den roten blutzellen enthaltenem hämoglobin
JP5539309B2 (ja) 2008-03-21 2014-07-02 アボット ポイント オブ ケア インコーポレイテッド 赤血球中に含まれるヘモグロビンの固有色素を利用して血液試料の赤血球指数を決定するための方法及び装置
EP3109621A1 (de) 2008-03-21 2016-12-28 Abbott Point Of Care, Inc. Vorrichtung zur analyse einzelner zellen oder partikeln in einer blutprobe auf der grundlage von fluoreszenzbildern und bildern der optischen dichte der probe
JP4887464B2 (ja) * 2008-03-21 2012-02-29 アボット ポイント オブ ケア インコーポレイテッド 生体試料を撮像するように構成された撮像機器の焦点位置を決定するための方法及び装置
ES2416404T3 (es) * 2008-04-02 2013-07-31 Abbott Point Of Care, Inc. Disolución en gradiente de auto-calibración en un ensayo de constituyentes y aparato de disolución en gradiente realizado en una muestra de película delgada
CA2720077C (en) * 2008-04-09 2014-08-05 Abbott Point Of Care, Inc. Method for measuring the area of a sample disposed within an analysis chamber
WO2009126505A1 (en) * 2008-04-09 2009-10-15 Abbott Point Of Care, Inc. Method of detecting very low levels of analyte within a thin film fluid sample contained in a thin thickness chamber
US20100255605A1 (en) * 2009-04-02 2010-10-07 Abbott Point Of Care, Inc. Method and device for transferring biologic fluid samples
CN103154735B (zh) * 2009-05-11 2018-10-02 连接Dx股份有限公司 用于检测分析物的方法和组合物
EP2519820B1 (de) * 2009-12-31 2013-11-06 Abbott Point Of Care, Inc. Verfahren und vorrichtung zur bestimmung des mittleren zellvolumen roter blutzellen
WO2011116305A1 (en) 2010-03-18 2011-09-22 Abbott Point Of Care, Inc. Method and apparatus for optically determining at least one hemoglobin related parameter of a whole blood sample
CN102128796B (zh) * 2010-12-07 2012-07-25 桂林理工大学 一种测定硫酸庆大霉素的方法
US9476871B2 (en) * 2012-05-02 2016-10-25 Diatech Oncology Llc System and method for automated determination of the relative effectiveness of anti-cancer drug candidates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3059524A (en) * 1958-06-04 1962-10-23 Grassmann Wolfgang Method and apparatus for the continuous colorimetric determination of the individualcomponents of a mixture
US4204839A (en) * 1978-08-09 1980-05-27 Eastman Kodak Company Fluorimetric analysis method for bilirubin
US4274744A (en) * 1978-11-21 1981-06-23 Medico Electronic, Inc. Direct reading digital colorimeter
US4329149A (en) * 1980-03-06 1982-05-11 Hach Chemical Company Method for spectrophotometric compensation for colorimetric reagent variation
DE3019612A1 (de) * 1980-05-22 1981-11-26 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisiertes thrombinpraeparat
JPS5832168A (ja) * 1981-08-19 1983-02-25 Olympus Optical Co Ltd 分析装置
US4506626A (en) * 1981-11-02 1985-03-26 Schurman Richard H Apparatus for controlling the proportions of a fluid
US4543335A (en) * 1982-12-20 1985-09-24 Miles Laboratories, Inc. Device and method for the quantitative determination of heparin in mammalian blood plasma
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US4911549A (en) * 1988-04-05 1990-03-27 Baxter International Inc. Heparin monitoring system and methodology

Also Published As

Publication number Publication date
FI922478A0 (fi) 1992-05-29
WO1991008461A1 (en) 1991-06-13
EP0502983A1 (de) 1992-09-16
KR920704118A (ko) 1992-12-19
AU655577B2 (en) 1995-01-05
IE904276A1 (en) 1991-06-05
JPH05502723A (ja) 1993-05-13
EP0502983A4 (en) 1993-05-05
CA2069887A1 (en) 1991-06-02
KR100210736B1 (ko) 1999-07-15
DE69028312T2 (de) 1997-01-16
GR3021261T3 (en) 1997-01-31
AU1628795A (en) 1995-06-29
DK0502983T3 (de) 1997-01-20
AU6951291A (en) 1991-06-26
IE75698B1 (en) 1997-09-10
US5068181A (en) 1991-11-26
JP2902108B2 (ja) 1999-06-07
FI101575B (fi) 1998-07-15
ATE142018T1 (de) 1996-09-15
EP0502983B1 (de) 1996-08-28
FI101575B1 (fi) 1998-07-15
ES2095310T3 (es) 1997-02-16
CA2069887C (en) 2004-02-10
FI922478A (fi) 1992-05-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TRINITY BIOTECH MANUFACTURING LTD., WICKLOW, IE

8327 Change in the person/name/address of the patent owner

Owner name: TCOAG IRELAND LTD., DUBLIN, IE