DE68904928D1 - Verfahren zur herstellung von 4-aryl-disubstituierten-1-tetralonen. - Google Patents
Verfahren zur herstellung von 4-aryl-disubstituierten-1-tetralonen.Info
- Publication number
- DE68904928D1 DE68904928D1 DE8989401577T DE68904928T DE68904928D1 DE 68904928 D1 DE68904928 D1 DE 68904928D1 DE 8989401577 T DE8989401577 T DE 8989401577T DE 68904928 T DE68904928 T DE 68904928T DE 68904928 D1 DE68904928 D1 DE 68904928D1
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- tetralones
- producing
- denotes halogen
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
- KJCVRFUGPWSIIH-UHFFFAOYSA-N 1-naphthol Chemical compound C1=CC=C2C(O)=CC=CC2=C1 KJCVRFUGPWSIIH-UHFFFAOYSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/512—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being a free hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8807641A FR2632633B1 (fr) | 1988-06-08 | 1988-06-08 | Procede de preparation de 4-aryl-1-tetralones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE68904928D1 true DE68904928D1 (de) | 1993-03-25 |
| DE68904928T2 DE68904928T2 (de) | 1993-08-19 |
Family
ID=9367081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8989401577T Expired - Lifetime DE68904928T2 (de) | 1988-06-08 | 1989-06-07 | Verfahren zur herstellung von 4-aryl-disubstituierten-1-tetralonen. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5019655A (de) |
| EP (1) | EP0346226B1 (de) |
| JP (1) | JP2543983B2 (de) |
| AT (1) | ATE85791T1 (de) |
| CA (1) | CA1339378C (de) |
| DE (1) | DE68904928T2 (de) |
| DK (1) | DK171020B1 (de) |
| ES (1) | ES2045489T3 (de) |
| FR (1) | FR2632633B1 (de) |
| IE (1) | IE62753B1 (de) |
| PT (1) | PT90785B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69406553T2 (de) * | 1993-11-30 | 1998-02-26 | Pfizer Inc., New York, N.Y. | Verfahren zur herstellung von chiralen tetralonen |
| HU218599B (hu) * | 1996-10-09 | 2000-10-28 | EGIS Gyógyszergyár Rt. | Eljárás 4-(3,4-diklór-fenil)-3,4-dihidro-1-(2H)-naftalin-1-on előállítására |
| FR2777000B1 (fr) | 1998-04-01 | 2002-09-27 | Catalys | Procede de preparation de la sertraline racemique |
| US6054614A (en) * | 1998-04-23 | 2000-04-25 | Ciba Specialty Chemicals Corporation | Process for the preparation of tetralone imines for the preparation of active pharmaceutical compounds |
| US6103938A (en) * | 1998-04-23 | 2000-08-15 | Ciba Specialty Chemicals Corporation | Process for preparing 4-(substituted phenyl)-3,4-dihydro-2H-naphthalen-1-ones |
| ATE295349T1 (de) | 1999-11-16 | 2005-05-15 | Ciba Sc Holding Ag | Verfahren zur herstellung von ketiminen |
| US6723878B2 (en) | 2001-06-15 | 2004-04-20 | Orion Corporation Fermion | Method for preparing sertraline |
| CN116041160A (zh) * | 2021-10-28 | 2023-05-02 | 上虞京新药业有限公司 | 一种将异舍曲酮转化为舍曲酮的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4029731A (en) * | 1974-11-06 | 1977-06-14 | Pfizer Inc. | Aminophenyltetralin compounds |
| US4045488A (en) * | 1974-11-06 | 1977-08-30 | Pfizer Inc. | Aminophenyltetralin compounds |
| US4536518A (en) * | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
-
1988
- 1988-06-08 FR FR8807641A patent/FR2632633B1/fr not_active Expired - Lifetime
-
1989
- 1989-06-07 DE DE8989401577T patent/DE68904928T2/de not_active Expired - Lifetime
- 1989-06-07 ES ES89401577T patent/ES2045489T3/es not_active Expired - Lifetime
- 1989-06-07 EP EP89401577A patent/EP0346226B1/de not_active Expired - Lifetime
- 1989-06-07 AT AT89401577T patent/ATE85791T1/de not_active IP Right Cessation
- 1989-06-07 DK DK279289A patent/DK171020B1/da not_active IP Right Cessation
- 1989-06-07 CA CA000602052A patent/CA1339378C/en not_active Expired - Fee Related
- 1989-06-08 JP JP1146546A patent/JP2543983B2/ja not_active Expired - Lifetime
- 1989-06-08 PT PT90785A patent/PT90785B/pt not_active IP Right Cessation
- 1989-06-08 US US07/363,252 patent/US5019655A/en not_active Expired - Lifetime
- 1989-06-12 IE IE184089A patent/IE62753B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0236142A (ja) | 1990-02-06 |
| IE62753B1 (en) | 1995-02-22 |
| FR2632633B1 (fr) | 1991-04-05 |
| PT90785A (pt) | 1989-12-29 |
| DE68904928T2 (de) | 1993-08-19 |
| ATE85791T1 (de) | 1993-03-15 |
| DK171020B1 (da) | 1996-04-22 |
| EP0346226A1 (de) | 1989-12-13 |
| ES2045489T3 (es) | 1994-01-16 |
| DK279289A (da) | 1989-12-09 |
| IE891840L (en) | 1989-12-08 |
| FR2632633A1 (fr) | 1989-12-15 |
| EP0346226B1 (de) | 1993-02-17 |
| US5019655A (en) | 1991-05-28 |
| DK279289D0 (da) | 1989-06-07 |
| PT90785B (pt) | 1994-10-31 |
| CA1339378C (en) | 1997-08-26 |
| JP2543983B2 (ja) | 1996-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SYLACHIM, CHASSE SUR RHONE, FR |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: FINORGA SA., CHASSE SUR RHONE, FR |