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DE60221795D1 - Orale zusammensetzungen von itraconazol und verfahren zu herstellung derselbigen - Google Patents

Orale zusammensetzungen von itraconazol und verfahren zu herstellung derselbigen

Info

Publication number
DE60221795D1
DE60221795D1 DE60221795T DE60221795T DE60221795D1 DE 60221795 D1 DE60221795 D1 DE 60221795D1 DE 60221795 T DE60221795 T DE 60221795T DE 60221795 T DE60221795 T DE 60221795T DE 60221795 D1 DE60221795 D1 DE 60221795D1
Authority
DE
Germany
Prior art keywords
itraconazole
acid
working solution
particles
coated particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60221795T
Other languages
English (en)
Other versions
DE60221795T2 (de
Inventor
Ranga Raju Namburi
John Elgin Kerr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stiefel Research Australia Pty Ltd
Stiefel Laboratories Inc
Original Assignee
Stiefel Research Australia Pty Ltd
Stiefel Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stiefel Research Australia Pty Ltd, Stiefel Laboratories Inc filed Critical Stiefel Research Australia Pty Ltd
Publication of DE60221795D1 publication Critical patent/DE60221795D1/de
Application granted granted Critical
Publication of DE60221795T2 publication Critical patent/DE60221795T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE60221795T 2001-02-06 2002-02-01 Orale zusammensetzungen von itraconazol und verfahren zu herstellung derselbigen Expired - Fee Related DE60221795T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26665301P 2001-02-06 2001-02-06
US266653P 2001-02-06
US09/933,032 US6663897B2 (en) 2001-02-06 2001-08-20 Oral itraconazole formulations and methods of making the same
US933032 2001-08-20
PCT/NL2002/000080 WO2002062318A2 (en) 2001-02-06 2002-02-01 Oral itraconazole formulations and methods of making the same

Publications (2)

Publication Number Publication Date
DE60221795D1 true DE60221795D1 (de) 2007-09-27
DE60221795T2 DE60221795T2 (de) 2007-12-27

Family

ID=26951964

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60221795T Expired - Fee Related DE60221795T2 (de) 2001-02-06 2002-02-01 Orale zusammensetzungen von itraconazol und verfahren zu herstellung derselbigen

Country Status (9)

Country Link
US (1) US6663897B2 (de)
EP (1) EP1357899B1 (de)
JP (1) JP2004521897A (de)
AT (1) ATE369840T1 (de)
AU (1) AU2002233822A1 (de)
CA (1) CA2437372A1 (de)
DE (1) DE60221795T2 (de)
MX (1) MXPA03006980A (de)
WO (1) WO2002062318A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015239D0 (en) * 2000-06-21 2000-08-16 Biochemie Gmbh Organic compounds
US8071133B2 (en) 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
US20040115266A1 (en) * 2002-02-01 2004-06-17 Namburi Ranga Raju Oral itraconazole formulations and methods of making the same
US7446107B2 (en) 2002-02-15 2008-11-04 Transform Pharmaceuticals, Inc. Crystalline forms of conazoles and methods of making and using the same
US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US7790905B2 (en) 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
JP4906233B2 (ja) 2002-03-01 2012-03-28 ユニバーシティー オブ サウス フロリダ 少なくとも１種の有効薬剤成分を含有する多構成要素固相
GB0205253D0 (en) * 2002-03-06 2002-04-17 Univ Gent Immediate release pharmaceutical granule compositions and a continuous process for making them
EP1511490A4 (de) 2002-05-31 2009-03-11 Transform Pharmaceuticals Inc Neue kristalline conazol-formen und verwandte prozesse, pharmazeutische zusammensetzungen und verfahren
CN100360117C (zh) 2002-06-21 2008-01-09 转化医药公司 具有提高的溶出度的药物组合物
WO2004012714A1 (en) * 2002-08-05 2004-02-12 Dsm Ip Assets B.V. Oral dosage forms of water insoluble drugs and methods of making the same
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
US20050074494A1 (en) * 2003-10-06 2005-04-07 Xiu-Xiu Cheng Itraconazole immediate release formulation
US20050118265A1 (en) * 2003-11-28 2005-06-02 Anandi Krishnan Antifungal oral dosage forms and the methods for preparation
GB0612695D0 (en) * 2006-06-27 2006-08-09 Univ Gent Process for preparing a solid dosage form

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791111A (en) 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
PH30929A (en) * 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
IT1263831B (it) 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina
CN1228693A (zh) * 1996-06-28 1999-09-15 先灵公司 含有三唑类抗真菌化合物的口服组合物
FR2758461A1 (fr) 1997-01-17 1998-07-24 Pharma Pass Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation
CZ295502B6 (cs) * 1997-03-26 2005-08-17 Janssen Pharmaceutica N. V. Antifungální peleta, způsob její přípravy a farmaceutická dávková forma s obsahem těchto pelet
IL137665A0 (en) * 1998-07-17 2001-10-31 Janssen Pharmaceutica Nv Pellets having core coated with an antifungal and a polymer
WO2000030616A1 (en) 1998-11-20 2000-06-02 Rtp Pharma Inc. Dispersible phospholipid stabilized microparticles
CA2362728C (en) 1999-03-24 2009-06-23 Fmc Corporation Improved aqueous solubility pharmaceutical formulations
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
KR100331529B1 (ko) 1999-06-16 2002-04-06 민경윤 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법

Also Published As

Publication number Publication date
AU2002233822A1 (en) 2002-08-19
EP1357899A2 (de) 2003-11-05
WO2002062318A3 (en) 2002-11-21
CA2437372A1 (en) 2002-08-15
WO2002062318A2 (en) 2002-08-15
ATE369840T1 (de) 2007-09-15
JP2004521897A (ja) 2004-07-22
MXPA03006980A (es) 2004-10-15
DE60221795T2 (de) 2007-12-27
EP1357899B1 (de) 2007-08-15
US20020150620A1 (en) 2002-10-17
US6663897B2 (en) 2003-12-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee