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DE60119905D1 - Verfahren zur herstellung fester dispersionen - Google Patents

Verfahren zur herstellung fester dispersionen

Info

Publication number
DE60119905D1
DE60119905D1 DE60119905T DE60119905T DE60119905D1 DE 60119905 D1 DE60119905 D1 DE 60119905D1 DE 60119905 T DE60119905 T DE 60119905T DE 60119905 T DE60119905 T DE 60119905T DE 60119905 D1 DE60119905 D1 DE 60119905D1
Authority
DE
Germany
Prior art keywords
methods
solid dispersions
substances
preparing solid
dispersions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60119905T
Other languages
English (en)
Other versions
DE60119905T2 (de
Inventor
Arne Brodin
Sylvan Frank
Chao Ye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio State University Research Foundation
Original Assignee
Ohio State University Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0000934A external-priority patent/SE0000934D0/xx
Application filed by Ohio State University Research Foundation filed Critical Ohio State University Research Foundation
Publication of DE60119905D1 publication Critical patent/DE60119905D1/de
Application granted granted Critical
Publication of DE60119905T2 publication Critical patent/DE60119905T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60119905T 2000-03-09 2001-03-08 Verfahren zur Herstellung von Feststoffdispersionen Expired - Lifetime DE60119905T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18798400P 2000-03-09 2000-03-09
US187984P 2000-03-09
SE0000934A SE0000934D0 (sv) 2000-03-21 2000-03-21 Method of preparing pharmaceutical compositions
SE0000934 2000-03-21
PCT/SE2001/000499 WO2001066091A1 (en) 2000-03-09 2001-03-08 Method of preparing solid dispersions

Publications (2)

Publication Number Publication Date
DE60119905D1 true DE60119905D1 (de) 2006-06-29
DE60119905T2 DE60119905T2 (de) 2007-01-11

Family

ID=26655029

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60119905T Expired - Lifetime DE60119905T2 (de) 2000-03-09 2001-03-08 Verfahren zur Herstellung von Feststoffdispersionen

Country Status (11)

Country Link
US (1) US20030104065A1 (de)
EP (1) EP1263413B1 (de)
JP (1) JP2003525895A (de)
AT (1) ATE326949T1 (de)
AU (1) AU2001239625A1 (de)
CY (1) CY1105515T1 (de)
DE (1) DE60119905T2 (de)
DK (1) DK1263413T3 (de)
ES (1) ES2263600T3 (de)
PT (1) PT1263413E (de)
WO (1) WO2001066091A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
DE10358749A1 (de) * 2003-12-12 2005-07-14 Lts Lohmann Therapie-Systeme Ag Darreichungsform zur Bekämpfung von primären Kopfschmerzen
US8475845B2 (en) 2005-07-15 2013-07-02 Map Pharmaceuticals, Inc. Method of particle formation
ATE521337T1 (de) * 2007-07-18 2011-09-15 Feyecon Bv Verfahren zur herstellung einer pharmazeutischen co-kristall-zusammensetzung
JP5632835B2 (ja) * 2009-05-29 2014-11-26 森下仁丹株式会社 口腔用薬剤組成物およびそれを封入した口腔用薬剤カプセル
JP5941072B2 (ja) * 2011-03-07 2016-06-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルデバイス及び方法
FR2987266B1 (fr) * 2012-02-28 2014-12-19 Debregeas Et Associes Pharma Procede d'obtention d'une composition pharmaceutique a base de modafinil, composition pharmaceutique ainsi obtenue et son application
WO2015071841A1 (en) 2013-11-12 2015-05-21 Druggability Technologies Holdings Limited Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them
CN108096195B (zh) * 2018-01-08 2020-01-24 中国药科大学 超临界抗溶剂法制备阿齐沙坦固体分散体的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169433A (en) * 1990-07-18 1992-12-08 Formulogics, Inc. Method of preparing mixtures of active ingredients and excipients using liquid carbon dioxide
AU5171293A (en) * 1992-10-14 1994-05-09 Regents Of The University Of Colorado, The Ion-pairing of drugs for improved efficacy and delivery
SI9400079B (sl) * 1994-02-15 2003-02-28 Dr. Weidner Eckhard, Dipl. Ing. Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom
JP2001505190A (ja) * 1996-10-14 2001-04-17 エフ・ホフマン―ラ ロシュ アーゲー 微粉状調製物の調製方法
US5955475A (en) * 1997-06-30 1999-09-21 Endo Pharmaceuticals Inc. Process for manufacturing paroxetine solid dispersions
US6299906B1 (en) * 1998-04-09 2001-10-09 Hoffmann-La Roche Inc. Process for making submicron particles
US6177103B1 (en) * 1998-06-19 2001-01-23 Rtp Pharma, Inc. Processes to generate submicron particles of water-insoluble compounds
US20020041898A1 (en) * 2000-01-05 2002-04-11 Unger Evan C. Novel targeted delivery systems for bioactive agents

Also Published As

Publication number Publication date
DK1263413T3 (da) 2006-09-11
JP2003525895A (ja) 2003-09-02
US20030104065A1 (en) 2003-06-05
ES2263600T3 (es) 2006-12-16
DE60119905T2 (de) 2007-01-11
EP1263413B1 (de) 2006-05-24
ATE326949T1 (de) 2006-06-15
CY1105515T1 (el) 2010-07-28
PT1263413E (pt) 2006-08-31
WO2001066091A1 (en) 2001-09-13
AU2001239625A1 (en) 2001-09-17
EP1263413A1 (de) 2002-12-11

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