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DE60214361D1 - Verfahren zur herstellung von gallensäure - Google Patents

Verfahren zur herstellung von gallensäure

Info

Publication number
DE60214361D1
DE60214361D1 DE60214361T DE60214361T DE60214361D1 DE 60214361 D1 DE60214361 D1 DE 60214361D1 DE 60214361 T DE60214361 T DE 60214361T DE 60214361 T DE60214361 T DE 60214361T DE 60214361 D1 DE60214361 D1 DE 60214361D1
Authority
DE
Germany
Prior art keywords
gallen
acid
production
relates
bile acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60214361T
Other languages
English (en)
Other versions
DE60214361T2 (de
Inventor
Peter Faarup
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE60214361D1 publication Critical patent/DE60214361D1/de
Application granted granted Critical
Publication of DE60214361T2 publication Critical patent/DE60214361T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60214361T 2001-05-02 2002-04-18 Verfahren zur herstellung von gallensäure Expired - Fee Related DE60214361T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200100688 2001-05-02
DK200100688 2001-05-02
PCT/DK2002/000250 WO2002088166A1 (en) 2001-05-02 2002-04-18 Preparation of bile acids

Publications (2)

Publication Number Publication Date
DE60214361D1 true DE60214361D1 (de) 2006-10-12
DE60214361T2 DE60214361T2 (de) 2007-09-13

Family

ID=8160465

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60214361T Expired - Fee Related DE60214361T2 (de) 2001-05-02 2002-04-18 Verfahren zur herstellung von gallensäure

Country Status (6)

Country Link
EP (2) EP1698636A1 (de)
JP (1) JP2004529160A (de)
AT (1) ATE338055T1 (de)
DE (1) DE60214361T2 (de)
ES (1) ES2271255T3 (de)
WO (1) WO2002088166A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006006718A1 (ja) * 2004-07-13 2006-01-19 Mitsubishi Chemical Corporation ステロイド化合物の製造方法
JP2007210888A (ja) 2006-01-12 2007-08-23 Mitsubishi Chemicals Corp ステロイド化合物の製造方法
US8242294B2 (en) 2007-06-19 2012-08-14 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
JOP20180077A1 (ar) 2007-06-19 2019-01-30 Kythera Biopharmaceuticals Inc تركيبات وطرق لحمض صفراوي تخليقي
US20080318870A1 (en) 2007-06-19 2008-12-25 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
WO2012021133A1 (en) 2010-08-12 2012-02-16 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
CN111560045A (zh) * 2020-06-23 2020-08-21 江苏佳尔科药业集团股份有限公司 一种以ba为原料合成石胆酸的方法
CN112375117A (zh) * 2020-11-14 2021-02-19 湖南科瑞生物制药股份有限公司 石胆酸及其中间体的制备方法
CN115466300B (zh) * 2022-10-18 2024-10-22 湖南科瑞生物制药股份有限公司 一种胆酸中间体a7及其合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2398709A (en) * 1940-10-07 1946-04-16 George A Breon & Company Hydroxycholanic acids
NZ273285A (en) * 1993-09-17 1997-10-24 Novo Nordisk As Insulin derivatives and compositions thereof
DE59510092D1 (de) * 1994-07-25 2002-04-11 Roche Diagnostics Gmbh Hapten-markierte peptide
DE69737479D1 (de) * 1996-08-30 2007-04-26 Novo Nordisk As Glp-1 derivate
JPH1160594A (ja) * 1997-08-25 1999-03-02 Sankyo Co Ltd 胆汁酸誘導体
WO1999048907A1 (de) * 1998-03-23 1999-09-30 Cognis Deutschland Gmbh Verfahren zur herstellung von stanolen
GB2355009A (en) * 1999-07-30 2001-04-11 Univ Glasgow Peptides conjugated to bile acids/salts

Also Published As

Publication number Publication date
WO2002088166A1 (en) 2002-11-07
JP2004529160A (ja) 2004-09-24
EP1385867B1 (de) 2006-08-30
EP1385867A1 (de) 2004-02-04
ATE338055T1 (de) 2006-09-15
DE60214361T2 (de) 2007-09-13
ES2271255T3 (es) 2007-04-16
EP1698636A1 (de) 2006-09-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee