DE60118527D1 - Sensible und multiplexe diagnostische tests zur proteinanalyse - Google Patents
Sensible und multiplexe diagnostische tests zur proteinanalyseInfo
- Publication number
- DE60118527D1 DE60118527D1 DE60118527T DE60118527T DE60118527D1 DE 60118527 D1 DE60118527 D1 DE 60118527D1 DE 60118527 T DE60118527 T DE 60118527T DE 60118527 T DE60118527 T DE 60118527T DE 60118527 D1 DE60118527 D1 DE 60118527D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- protein
- binding reagents
- sample
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1051—Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17787300P | 2000-01-24 | 2000-01-24 | |
| PCT/US2001/000291 WO2001053539A1 (en) | 2000-01-24 | 2001-01-04 | Sensitive, multiplexed diagnostic assays for protein analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60118527D1 true DE60118527D1 (de) | 2006-05-18 |
Family
ID=22650272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60118527T Expired - Lifetime DE60118527D1 (de) | 2000-01-24 | 2001-01-04 | Sensible und multiplexe diagnostische tests zur proteinanalyse |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6489116B2 (de) |
| EP (1) | EP1250463B1 (de) |
| JP (1) | JP2003520050A (de) |
| AT (1) | ATE322558T1 (de) |
| AU (1) | AU783689B2 (de) |
| CA (1) | CA2396810A1 (de) |
| DE (1) | DE60118527D1 (de) |
| WO (1) | WO2001053539A1 (de) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1377828A4 (de) * | 2001-04-10 | 2006-11-15 | Childrens Medical Center | Verfahren zur analyse und markierung von protein-protein-wechselwirkungen |
| WO2002102820A1 (en) | 2001-06-20 | 2002-12-27 | Nuevolution A/S | Nucleoside derivatives for library preparation |
| EP1419274A4 (de) * | 2001-07-31 | 2006-02-08 | Phylos Inc | Modulare konstruktion von nukleinsäure-protein-fusionsmultimeren |
| DE10145226A1 (de) * | 2001-09-13 | 2003-04-10 | Lifebits Ag | Herstellung von trägergebundenen Molekülen |
| US7045311B2 (en) * | 2001-10-25 | 2006-05-16 | Monogram Biosciences, Inc. | Whole cell assay systems for cell surface proteases |
| WO2003045975A2 (en) * | 2001-11-27 | 2003-06-05 | Compound Therapeutics, Inc. | Solid-phase immobilization of proteins and peptides |
| AU2003209272A1 (en) * | 2002-01-16 | 2003-09-02 | Zyomyx, Inc. | Engineered binding proteins |
| US20030166010A1 (en) * | 2002-02-25 | 2003-09-04 | Affholter Joseph A. | Custom ligand design for biomolecular filtration and purification for bioseperation |
| EP2186897B1 (de) | 2002-03-15 | 2016-02-17 | Nuevolution A/S | Eine verbesserte Methode zur Synthese von matritzenabhängigen Molekülen |
| US20030198973A1 (en) * | 2002-04-23 | 2003-10-23 | The Molecular Sciences Institute, Inc. | Chimeric fusion molecule for analyte detection and quantitation |
| US7402397B2 (en) | 2002-05-21 | 2008-07-22 | Monogram Biosciences, Inc. | Detecting and profiling molecular complexes |
| US20040229294A1 (en) | 2002-05-21 | 2004-11-18 | Po-Ying Chan-Hui | ErbB surface receptor complexes as biomarkers |
| AU2003247266A1 (en) | 2002-08-01 | 2004-02-23 | Nuevolution A/S | Multi-step synthesis of templated molecules |
| ES2640279T3 (es) | 2002-10-30 | 2017-11-02 | Nuevolution A/S | Procedimiento para la síntesis de un complejo bifuncional |
| ATE450609T1 (de) | 2002-12-19 | 2009-12-15 | Nuevolution As | Durch quasizufallsstrukturen und funktionen geführte synthesemethode |
| US20070026397A1 (en) | 2003-02-21 | 2007-02-01 | Nuevolution A/S | Method for producing second-generation library |
| CA2522753C (en) * | 2003-04-18 | 2014-06-10 | Becton, Dickinson And Company | Immuno-amplification |
| WO2004104229A2 (en) * | 2003-05-16 | 2004-12-02 | Vickery Michael C L | Internal control nucleic acid molecule for nucleic acid amplification systems |
| US7713923B2 (en) | 2003-06-25 | 2010-05-11 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
| DK1636250T3 (en) * | 2003-06-25 | 2016-02-22 | Massachusetts Inst Technology | SELF-ORGANIZING PEPTIDES, CONTAINING MODIFICATIONS, AND APPLICATIONS THEREOF |
| DK1670939T3 (da) * | 2003-09-18 | 2010-03-01 | Nuevolution As | Fremgangsmåde til opnåelse af strukturel information om et kodet molekyle og fremgangsmåde til udvælgelse af forbindelser |
| EP1681983A4 (de) * | 2003-10-14 | 2008-12-10 | Monogram Biosciences Inc | Rezeptor-tyrosin-kinase-signalpfad-analyse für diagnose und therapie |
| US7785843B2 (en) * | 2004-06-23 | 2010-08-31 | Sequenom, Inc. | Target-specific compomers and methods of use |
| US20060110724A1 (en) | 2004-11-19 | 2006-05-25 | Burkhardt William Iii | Quantitative real-time assay for noroviruses and enteroviruses with built in quality control standard |
| US20060204999A1 (en) * | 2005-03-14 | 2006-09-14 | Stephen Macevicz | Detecting molecular complexes |
| KR20100102750A (ko) * | 2005-04-25 | 2010-09-24 | 메사추세츠 인스티튜트 오브 테크놀로지 | 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법 |
| CN106443006A (zh) | 2005-11-16 | 2017-02-22 | Ambrx公司 | 包括非天然氨基酸的方法和组合物 |
| DK3018206T3 (da) | 2005-12-01 | 2021-11-15 | Nuevolution As | Enzymatic encoding methods for efficient synthesis of large libraries |
| WO2007142757A2 (en) | 2006-04-25 | 2007-12-13 | Massachusetts Institute Of Technology | Compositions and methods for affecting movement of contaminants, bodily fluids or other entities and/or affecting other physiological conditions |
| EP2860194B1 (de) * | 2006-09-26 | 2018-11-07 | Massachusetts Institute Of Technology | Modifizierte selbstanordnende Peptide |
| KR20210049186A (ko) | 2007-11-30 | 2021-05-04 | 애브비 바이오테크놀로지 리미티드 | 단백질 제형 및 이의 제조방법 |
| US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
| KR20110036638A (ko) | 2008-07-25 | 2011-04-07 | 리차드 더블유. 와그너 | 단백질 스크리닝 방법 |
| WO2011072482A1 (en) | 2009-12-14 | 2011-06-23 | The University Of Hong Kong | Nano cancer barrier device(ncbd) to immobilize and inhibit the division of metastic cancer stem cells |
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| EP2558577B1 (de) | 2010-04-16 | 2018-12-12 | Nuevolution A/S | Bifunktionelle komplexe und verfahren zur herstellung sowie verwendung derartiger komplexe |
| EP3798236B1 (de) | 2011-03-15 | 2022-08-10 | X-Body, Inc. | Antikörper-screening-verfahren |
| SI3415619T1 (sl) | 2011-04-28 | 2021-04-30 | The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel Building 170, Third Floor, Main Quad | Identifikacija polinukleotidov, povezanih z vzorcem |
| AU2012347972B2 (en) | 2011-12-05 | 2018-05-10 | X-Body, Inc. | PDGF receptor beta binding polypeptides |
| EP3321378B1 (de) | 2012-02-27 | 2021-11-10 | Becton, Dickinson and Company | Zusammensetzungen für molekularen zählung |
| KR102309517B1 (ko) | 2013-06-28 | 2021-10-07 | 엑스-바디 인코포레이티드 | 표적 항원 발견, 표현형 선별 및 표적 세포 특이성 표적 에피토프를 규명하기 위한 그의 용도 |
| DK3039158T3 (en) | 2013-08-28 | 2019-03-04 | Becton Dickinson Co | MASSIVE PARALLEL SINGLE CELL CELL ANALYSIS |
| US10519436B2 (en) | 2013-09-23 | 2019-12-31 | X-Body, Inc. | Methods and compositions for generation of binding agents against cell surface antigens |
| PT3152232T (pt) * | 2014-06-06 | 2020-02-19 | Herlev Hospital | Determinando o reconhecimento de antígenos através do código de barras dos multímeros cmh |
| US11585806B2 (en) * | 2014-06-13 | 2023-02-21 | Immudex Aps | General detection and isolation of specific cells by binding of labeled molecules |
| US9727810B2 (en) | 2015-02-27 | 2017-08-08 | Cellular Research, Inc. | Spatially addressable molecular barcoding |
| EP3277843A2 (de) | 2015-03-30 | 2018-02-07 | Cellular Research, Inc. | Verfahren und zusammensetzungen für kombinatorische barcodierung |
| WO2016172373A1 (en) | 2015-04-23 | 2016-10-27 | Cellular Research, Inc. | Methods and compositions for whole transcriptome amplification |
| WO2017044574A1 (en) | 2015-09-11 | 2017-03-16 | Cellular Research, Inc. | Methods and compositions for nucleic acid library normalization |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| AU2017331459B2 (en) | 2016-09-26 | 2023-04-13 | Becton, Dickinson And Company | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
| WO2018144240A1 (en) | 2017-02-01 | 2018-08-09 | Cellular Research, Inc. | Selective amplification using blocking oligonucleotides |
| CN110719959B (zh) | 2017-06-05 | 2021-08-06 | 贝克顿迪金森公司 | 针对单细胞的样品索引 |
| JP7407128B2 (ja) | 2018-05-03 | 2023-12-28 | ベクトン・ディキンソン・アンド・カンパニー | ハイスループットマルチオミクスサンプル解析 |
| CN112243461B (zh) | 2018-05-03 | 2024-07-12 | 贝克顿迪金森公司 | 在相对的转录物末端进行分子条形码化 |
| CN112805389B (zh) | 2018-10-01 | 2024-08-06 | 贝克顿迪金森公司 | 确定5’转录物序列 |
| WO2020097315A1 (en) | 2018-11-08 | 2020-05-14 | Cellular Research, Inc. | Whole transcriptome analysis of single cells using random priming |
| US11492660B2 (en) | 2018-12-13 | 2022-11-08 | Becton, Dickinson And Company | Selective extension in single cell whole transcriptome analysis |
| WO2020154247A1 (en) | 2019-01-23 | 2020-07-30 | Cellular Research, Inc. | Oligonucleotides associated with antibodies |
| CN113454234B (zh) | 2019-02-14 | 2025-03-18 | 贝克顿迪金森公司 | 杂合体靶向和全转录物组扩增 |
| CN114051534B (zh) | 2019-07-22 | 2025-02-21 | 贝克顿迪金森公司 | 单细胞染色质免疫沉淀测序测定 |
| EP4407041A3 (de) | 2019-11-08 | 2024-09-25 | Becton Dickinson and Company | Verwendung von random-rpiming zur gewinnung von v(d)j-informationen in voller länge für immunrepertoiresequenzierung |
| EP4090763B1 (de) | 2020-01-13 | 2024-12-04 | Becton Dickinson and Company | Verfahren und zusammensetzungen zur quantifizierung von proteinen und rna |
| EP4097228B1 (de) | 2020-01-29 | 2024-08-14 | Becton, Dickinson and Company | Barkodierte wells zur räumlichen abbildung einzelner zellen durch sequenzierung |
| EP4111168A1 (de) | 2020-02-25 | 2023-01-04 | Becton Dickinson and Company | Bispezifische sonden zur ermöglichung der verwendung von einzelzellenproben als einzelfarbkompensationssteuerung |
| CN115605614A (zh) | 2020-05-14 | 2023-01-13 | 贝克顿迪金森公司（Us） | 用于免疫组库谱分析的引物 |
| EP4407030A3 (de) | 2020-06-02 | 2024-09-11 | Becton, Dickinson and Company | Oligonukleotide und perlen für 5 prime genexpressionsassay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4587044A (en) | 1983-09-01 | 1986-05-06 | The Johns Hopkins University | Linkage of proteins to nucleic acids |
| DE3590766C2 (de) | 1985-03-30 | 1991-01-10 | Marc Genf/Geneve Ch Ballivet | |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
| ES2118066T3 (es) | 1989-10-05 | 1998-09-16 | Optein Inc | Sintesis y aislamiento, exentos de celulas, de nuevos genes y polipeptidos. |
| US5270163A (en) | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
| US5723286A (en) | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
| US5650489A (en) | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
| WO1992002536A1 (en) | 1990-08-02 | 1992-02-20 | The Regents Of The University Of Colorado | Systematic polypeptide evolution by reverse translation |
| US5264563A (en) | 1990-08-24 | 1993-11-23 | Ixsys Inc. | Process for synthesizing oligonucleotides with random codons |
| DE4112440C1 (de) | 1991-04-16 | 1992-10-22 | Diagen Institut Fuer Molekularbiologische Diagnostik Gmbh, 4000 Duesseldorf, De | |
| US5795747A (en) | 1991-04-16 | 1998-08-18 | Evotec Biosystems Gmbh | Process for manufacturing new biopolymers |
| AU2313392A (en) | 1991-08-01 | 1993-03-02 | University Research Corporation | Systematic polypeptide evolution by reverse translation |
| US5639603A (en) | 1991-09-18 | 1997-06-17 | Affymax Technologies N.V. | Synthesizing and screening molecular diversity |
| US5733731A (en) | 1991-10-16 | 1998-03-31 | Affymax Technologies N.V. | Peptide library and screening method |
| US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
| US5541061A (en) | 1992-04-29 | 1996-07-30 | Affymax Technologies N.V. | Methods for screening factorial chemical libraries |
| US5565324A (en) | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
| US6087186A (en) | 1993-07-16 | 2000-07-11 | Irori | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries |
| US5635602A (en) | 1993-08-13 | 1997-06-03 | The Regents Of The University Of California | Design and synthesis of bispecific DNA-antibody conjugates |
| AU8124694A (en) | 1993-10-29 | 1995-05-22 | Affymax Technologies N.V. | In vitro peptide and antibody display libraries |
| US5561043A (en) | 1994-01-31 | 1996-10-01 | Trustees Of Boston University | Self-assembling multimeric nucleic acid constructs |
| ES2201097T3 (es) | 1994-01-31 | 2004-03-16 | Trustees Of Boston University | Bibliotecas de anticuerpos policlonales. |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| EP0763202A4 (de) | 1994-05-23 | 1998-12-09 | Smithkline Beecham Corp | Kodierte kombinatorische bibliotheken |
| US5627024A (en) | 1994-08-05 | 1997-05-06 | The Scripps Research Institute | Lambdoid bacteriophage vectors for expression and display of foreign proteins |
| US5559000A (en) | 1995-01-18 | 1996-09-24 | The Scripps Research Institute | Encoded reaction cassette |
| US5751629A (en) | 1995-04-25 | 1998-05-12 | Irori | Remotely programmable matrices with memories |
| DE19646372C1 (de) | 1995-11-11 | 1997-06-19 | Evotec Biosystems Gmbh | Genotyp und Phänotyp koppelnde Verbindung |
| EP1477561B1 (de) | 1996-10-17 | 2008-12-10 | Mitsubishi Chemical Corporation | Molekül, welches Genotyp und Phänotyp zusammenführt und dessen Anwendungen |
| US6261804B1 (en) * | 1997-01-21 | 2001-07-17 | The General Hospital Corporation | Selection of proteins using RNA-protein fusions |
| EP0971946B1 (de) * | 1997-01-21 | 2006-07-05 | The General Hospital Corporation | Selektion von proteinen mittels rns-protein fusionen |
| GB9703369D0 (en) * | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
| GB9712512D0 (en) | 1997-06-16 | 1997-08-20 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
| DE69933369D1 (en) * | 1998-04-03 | 2006-11-09 | Compound Therapeutics Inc | Adressierbare protein arrays |
| US5985575A (en) | 1998-05-20 | 1999-11-16 | Wisconsin Alumni Research Foundation | Tethered function assay for protein function |
| DK1105360T3 (da) | 1998-08-17 | 2009-11-02 | Bristol Myers Squibb Co | Identifikation af forbindelse-protein-interaktioner ved anvendelse af biblioteker af protein-nukleinsyrefusionsmolekyler |
| WO2000032823A1 (en) | 1998-12-02 | 2000-06-08 | Phylos, Inc. | Dna-protein fusions and uses thereof |
| DK1137941T4 (da) | 1998-12-10 | 2014-01-06 | Brystol Myers Squibb Company | Protein-scaffolds til antistof-mimetika og andre bindingsproteiner |
-
2001
- 2001-01-04 EP EP01942678A patent/EP1250463B1/de not_active Expired - Lifetime
- 2001-01-04 AU AU29279/01A patent/AU783689B2/en not_active Ceased
- 2001-01-04 JP JP2001553398A patent/JP2003520050A/ja active Pending
- 2001-01-04 CA CA002396810A patent/CA2396810A1/en not_active Abandoned
- 2001-01-04 US US09/755,663 patent/US6489116B2/en not_active Expired - Lifetime
- 2001-01-04 AT AT01942678T patent/ATE322558T1/de not_active IP Right Cessation
- 2001-01-04 DE DE60118527T patent/DE60118527D1/de not_active Expired - Lifetime
- 2001-01-04 WO PCT/US2001/000291 patent/WO2001053539A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003520050A (ja) | 2003-07-02 |
| EP1250463A1 (de) | 2002-10-23 |
| US20010024784A1 (en) | 2001-09-27 |
| AU2927901A (en) | 2001-07-31 |
| ATE322558T1 (de) | 2006-04-15 |
| EP1250463B1 (de) | 2006-04-05 |
| EP1250463A4 (de) | 2004-03-24 |
| US6489116B2 (en) | 2002-12-03 |
| CA2396810A1 (en) | 2001-07-26 |
| WO2001053539A1 (en) | 2001-07-26 |
| AU783689B2 (en) | 2005-11-24 |
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