DE60045139D1 - Löslicher Interleukin-20-Rezeptor - Google Patents
Löslicher Interleukin-20-RezeptorInfo
- Publication number
- DE60045139D1 DE60045139D1 DE60045139T DE60045139T DE60045139D1 DE 60045139 D1 DE60045139 D1 DE 60045139D1 DE 60045139 T DE60045139 T DE 60045139T DE 60045139 T DE60045139 T DE 60045139T DE 60045139 D1 DE60045139 D1 DE 60045139D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor
- soluble interleukin
- immunoglobulin
- subunit
- fused
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108010001618 interleukin-20 receptor Proteins 0.000 title 1
- 101001044895 Homo sapiens Interleukin-20 receptor subunit beta Proteins 0.000 abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract 2
- 102100022706 Interleukin-20 receptor subunit alpha Human genes 0.000 abstract 2
- 102100022705 Interleukin-20 receptor subunit beta Human genes 0.000 abstract 2
- 102000018358 immunoglobulin Human genes 0.000 abstract 2
- 101001044893 Homo sapiens Interleukin-20 receptor subunit alpha Proteins 0.000 abstract 1
- 101710174006 Interleukin-20 receptor subunit alpha Proteins 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/7056—Lectin superfamily, e.g. CD23, CD72
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47177499A | 1999-12-23 | 1999-12-23 | |
US21341600P | 2000-06-22 | 2000-06-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60045139D1 true DE60045139D1 (de) | 2010-12-02 |
Family
ID=26908064
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60040240T Expired - Lifetime DE60040240D1 (de) | 1999-12-23 | 2000-12-22 | Löslicher interleukin-20 rezeptor |
DE60045139T Expired - Lifetime DE60045139D1 (de) | 1999-12-23 | 2000-12-22 | Löslicher Interleukin-20-Rezeptor |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60040240T Expired - Lifetime DE60040240D1 (de) | 1999-12-23 | 2000-12-22 | Löslicher interleukin-20 rezeptor |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP1246846B1 (de) |
JP (1) | JP4741139B2 (de) |
AT (2) | ATE407950T1 (de) |
AU (1) | AU783473B2 (de) |
CA (1) | CA2395539C (de) |
DE (2) | DE60040240D1 (de) |
DK (1) | DK1246846T3 (de) |
RU (1) | RU2279441C2 (de) |
UA (1) | UA84830C2 (de) |
WO (1) | WO2001046232A2 (de) |
Families Citing this family (93)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7122632B2 (en) | 1999-12-23 | 2006-10-17 | Zymogenetics, Inc. | Soluble Interleukin-20 receptor |
DK1246846T3 (da) | 1999-12-23 | 2008-12-08 | Zymogenetics Inc | Oplöselig interleukin-20-receptor |
EP2295079A3 (de) * | 1999-12-23 | 2011-03-23 | ZymoGenetics, L.L.C. | Verfahren zur Behandlung von Entzündungen |
US6610286B2 (en) | 1999-12-23 | 2003-08-26 | Zymogenetics, Inc. | Method for treating inflammation using soluble receptors to interleukin-20 |
US7045498B2 (en) | 2000-08-08 | 2006-05-16 | Zymogenetics, Inc. | Soluble Zcytor11 cytokine receptors |
DE60141546D1 (de) | 2000-09-15 | 2010-04-22 | Zymogenetics Inc | Polypeptide enthaltend extrazellulären Domäne von IL-20RA und/oderr IL-20RB |
KR20060125923A (ko) * | 2001-06-20 | 2006-12-06 | 제넨테크, 인크. | 종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물 |
WO2004085475A2 (en) | 2003-03-24 | 2004-10-07 | Zymogenetics, Inc. | Anti-il-20 antibodies and binding partners and methods of using in inflammation |
EP1653995A1 (de) | 2003-08-08 | 2006-05-10 | Novo Nordisk A/S | Interleukin-20 zur behandlung und diagnose von mit neovaskularization verbunden zuständen |
DK1725249T3 (en) | 2003-11-06 | 2014-03-17 | Seattle Genetics Inc | Monomethylvaline compounds capable of conjugating to ligands. |
EP1753463A2 (de) | 2004-06-01 | 2007-02-21 | Genentech, Inc. | Antikörper-wirkstoff-konjugate und verfahren |
US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
US7521541B2 (en) | 2004-09-23 | 2009-04-21 | Genetech Inc. | Cysteine engineered antibodies and conjugates |
US7537761B2 (en) | 2004-10-22 | 2009-05-26 | Zymogenetics, Inc. | Anti-IL-22RA antibodies and binding partners and methods of using in inflammation |
WO2006086396A2 (en) | 2005-02-08 | 2006-08-17 | Zymogenetics, Inc. | Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation |
WO2007131654A2 (de) * | 2006-05-17 | 2007-11-22 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Antientzündliches fusionsprotein |
KR101691534B1 (ko) * | 2008-10-07 | 2017-01-09 | 내셔날 쳉쿵 유니버시티 | 류마티스 관절염 및 골다공증 치료용 il-20 길항제의 용도 |
US8470980B2 (en) | 2009-09-09 | 2013-06-25 | Centrose, Llc | Extracellular targeted drug conjugates |
RS61082B1 (sr) | 2010-02-26 | 2020-12-31 | Novo Nordisk As | Stabilno antitelo koje sadrži kompozicije |
PT2528625E (pt) | 2010-04-15 | 2013-10-17 | Spirogen Sarl | Pirrolobenzodiazepinas e conjugados das mesmas |
CN105055306B (zh) | 2010-05-28 | 2019-10-01 | 诺沃—诺迪斯克有限公司 | 包含抗体和防腐剂的稳定的多剂量组合物 |
CN103068406B (zh) | 2010-06-08 | 2017-06-30 | 基因泰克公司 | 半胱氨酸改造的抗体和偶联物 |
JP5889912B2 (ja) | 2010-11-17 | 2016-03-22 | ジェネンテック, インコーポレイテッド | アラニニルメイタンシノール抗体コンジュゲート |
CN103608684B (zh) | 2011-05-12 | 2016-05-04 | 基因泰克公司 | 利用框架签名肽检测动物样品中的治疗性抗体的多重反应监测lc-ms/ms方法 |
CA2850371C (en) | 2011-10-14 | 2020-06-30 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
WO2013130093A1 (en) | 2012-03-02 | 2013-09-06 | Genentech, Inc. | Biomarkers for treatment with anti-tubulin chemotherapeutic compounds |
BR112015008238A2 (pt) | 2012-10-12 | 2017-11-28 | Adc Therapeutics Sarl | conjugados de pirrolbenzodiazepina-anticorpo anti-cd22 |
CN109134599A (zh) | 2012-10-12 | 2019-01-04 | 麦迪穆有限责任公司 | 吡咯并苯并二氮杂卓及其结合物 |
US10751346B2 (en) | 2012-10-12 | 2020-08-25 | Medimmune Limited | Pyrrolobenzodiazepine—anti-PSMA antibody conjugates |
EP2906297B1 (de) | 2012-10-12 | 2017-12-06 | ADC Therapeutics SA | Pyrrolobenzodiazepin-antikörper-konjugate |
ES2703151T3 (es) | 2012-10-12 | 2019-03-07 | Adc Therapeutics Sa | Conjugados de anticuerpos de pirrolobenzodiazepinas |
WO2014057114A1 (en) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Pyrrolobenzodiazepine-anti-psma antibody conjugates |
SI2906296T1 (en) | 2012-10-12 | 2018-06-29 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
WO2014096365A1 (en) | 2012-12-21 | 2014-06-26 | Spirogen Sàrl | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
CA2894961C (en) | 2012-12-21 | 2020-09-15 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
MX364330B (es) | 2013-03-13 | 2019-04-23 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de las mismas. |
JP6444902B2 (ja) | 2013-03-13 | 2018-12-26 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピン及びその結合体 |
MX363787B (es) | 2013-03-13 | 2019-04-03 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de los mismos. |
US10442836B2 (en) | 2013-08-12 | 2019-10-15 | Genentech, Inc. | 1-(chloromethyl)-2,3-dihydro-1H-benzo[E]indole dimer antibody-drug conjugate compounds, and methods of use and treatment |
US10010624B2 (en) | 2013-10-11 | 2018-07-03 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
EP3054985B1 (de) | 2013-10-11 | 2018-12-26 | Medimmune Limited | Pyrrolobenzodiazepin-antikörper-konjugate |
EP3054986B1 (de) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Pyrrolobenzodiazepin-antikörper-konjugate |
MX371092B (es) | 2013-12-16 | 2020-01-16 | Genentech Inc | Compuestos peptidomimeticos y conjugados de anticuerpo-farmaco de los mismos. |
CN105828840B (zh) | 2013-12-16 | 2020-08-04 | 基因泰克公司 | 1-(氯甲基)-2,3-二氢-1H-苯并[e]吲哚二聚体抗体-药物缀合物化合物及使用和治疗方法 |
PE20161394A1 (es) | 2013-12-16 | 2017-01-06 | Genentech Inc | Compuestos peptidomimeticos y sus conjugados de anticuerpo-farmaco |
RS59643B1 (sr) | 2014-06-06 | 2020-01-31 | Bristol Myers Squibb Co | Antitela na glukokortikoidom indukovani receptor faktora nekroze tumora (gitr) i njihova primena |
CN106687141A (zh) | 2014-09-10 | 2017-05-17 | 麦迪穆有限责任公司 | 吡咯并苯并二氮杂卓及其缀合物 |
GB201416112D0 (en) | 2014-09-12 | 2014-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
MX2017003123A (es) | 2014-09-12 | 2017-05-12 | Genentech Inc | Anticuerpos y conjugados modificados geneticamente con cisteina. |
WO2016040825A1 (en) | 2014-09-12 | 2016-03-17 | Genentech, Inc. | Anthracycline disulfide intermediates, antibody-drug conjugates and methods |
JP2017533887A (ja) | 2014-09-17 | 2017-11-16 | ジェネンテック, インコーポレイテッド | ピロロベンゾジアゼピン類及びその抗体ジスルフィドコンジュゲート |
EA202090956A3 (ru) | 2014-11-21 | 2020-12-30 | Бристол-Майерс Сквибб Компани | Антитела к cd73 и их применения |
BR112017010094A2 (pt) | 2014-11-21 | 2018-02-06 | Bristol-Myers Squibb Company | anticorpos compreendendo regiões constantes de cadeias pesadas modificadas |
US10780096B2 (en) | 2014-11-25 | 2020-09-22 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
JP6752204B2 (ja) | 2014-12-03 | 2020-09-09 | ジェネンテック, インコーポレイテッド | 四級アミン化合物及びその抗体−薬物コンジュゲート |
GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
EA201792497A1 (ru) | 2015-06-03 | 2018-05-31 | Бристол-Майерс Сквибб Компани | Антитела к gitr для диагностики злокачественной опухоли |
MA43345A (fr) | 2015-10-02 | 2018-08-08 | Hoffmann La Roche | Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation |
MA43354A (fr) | 2015-10-16 | 2018-08-22 | Genentech Inc | Conjugués médicamenteux à pont disulfure encombré |
MA45326A (fr) | 2015-10-20 | 2018-08-29 | Genentech Inc | Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation |
CA3005855A1 (en) | 2015-11-19 | 2017-05-26 | Bristol-Myers Squibb Company | Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof |
GB201601431D0 (en) | 2016-01-26 | 2016-03-09 | Medimmune Ltd | Pyrrolobenzodiazepines |
GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
CN108700598A (zh) | 2016-03-25 | 2018-10-23 | 豪夫迈·罗氏有限公司 | 多路总抗体和抗体缀合的药物量化测定法 |
GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
EP3458101B1 (de) | 2016-05-20 | 2020-12-30 | H. Hoffnabb-La Roche Ag | Protac-antikörper-konjugate und verfahren zur verwendung |
WO2017205741A1 (en) | 2016-05-27 | 2017-11-30 | Genentech, Inc. | Bioanalytical method for the characterization of site-specific antibody-drug conjugates |
US10639378B2 (en) | 2016-06-06 | 2020-05-05 | Genentech, Inc. | Silvestrol antibody-drug conjugates and methods of use |
CN109689111B (zh) | 2016-08-11 | 2024-04-05 | 基因泰克公司 | 吡咯并苯并二氮杂䓬前药及其抗体缀合物 |
WO2018065501A1 (en) | 2016-10-05 | 2018-04-12 | F. Hoffmann-La Roche Ag | Methods for preparing antibody drug conjugates |
GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
HRP20210979T1 (hr) | 2017-02-08 | 2021-09-17 | Adc Therapeutics Sa | Konjugati pirolobenzodiazepin-protutijelo |
GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
AU2018255876B2 (en) | 2017-04-18 | 2020-04-30 | Medimmune Limited | Pyrrolobenzodiazepine conjugates |
MX2019012464A (es) | 2017-04-20 | 2019-12-11 | Adc Therapeutics Sa | Terapia combinada con un conjugado de anticuerpo y farmaco anti-axl. |
WO2018213297A1 (en) | 2017-05-16 | 2018-11-22 | Bristol-Myers Squibb Company | Treatment of cancer with anti-gitr agonist antibodies |
UA127900C2 (uk) | 2017-06-14 | 2024-02-07 | Ейдісі Терапьютікс Са | Схема дозування для введення adc до cd19 |
HRP20220311T1 (hr) | 2017-08-18 | 2022-05-13 | Medimmune Limited | Konjugati pirolobenzodiazepina |
JP2020534300A (ja) | 2017-09-20 | 2020-11-26 | ピーエイチ・ファーマ・カンパニー・リミテッドPh Pharma Co., Ltd. | タイランスタチン類似体 |
KR101933217B1 (ko) | 2017-12-28 | 2018-12-27 | (주) 에빅스젠 | 피부 염증 억제용 펩티드 및 이를 포함하는 피부 염증 예방 또는 치료용 조성물 |
GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
EP3870235A1 (de) | 2018-10-24 | 2021-09-01 | F. Hoffmann-La Roche AG | Konjugierte chemische abbauauslöser und verwendungsverfahren |
CN113227119A (zh) | 2018-12-10 | 2021-08-06 | 基因泰克公司 | 用于与含Fc的蛋白质进行位点特异性缀合的光交联肽 |
GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
KR20210139270A (ko) | 2019-03-15 | 2021-11-22 | 메드임뮨 리미티드 | 암의 치료에 사용하기 위한 아제티도벤조디아제핀 이량체 및 이를 포함하는 컨쥬게이트 |
EP4426727A2 (de) | 2021-11-03 | 2024-09-11 | Hangzhou Dac Biotech Co., Ltd. | Spezifische konjugation eines antikörpers |
WO2024138128A2 (en) | 2022-12-23 | 2024-06-27 | Genentech, Inc. | Cereblon degrader conjugates, and uses thereof |
WO2024220546A2 (en) | 2023-04-17 | 2024-10-24 | Peak Bio, Inc. | Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0659439B1 (de) * | 1993-12-24 | 2001-10-24 | MERCK PATENT GmbH | Immunokonjugate |
WO2000073454A1 (en) * | 1999-06-02 | 2000-12-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US5945511A (en) * | 1997-02-20 | 1999-08-31 | Zymogenetics, Inc. | Class II cytokine receptor |
EP1012260A4 (de) * | 1997-07-16 | 2001-05-09 | Human Genome Sciences Inc | Interleukin-20 |
PL198687B1 (pl) | 1997-11-26 | 2008-07-31 | Zymogenetics Inc | Zastosowanie polipeptydu do wytwarzania leku |
AU737592B2 (en) * | 1998-01-23 | 2001-08-23 | Immunex Corporation | Il-18 receptors |
WO1999046379A2 (en) * | 1998-03-09 | 1999-09-16 | Schering Corporation | Human receptor proteins; related reagents and methods |
NZ507435A (en) * | 1998-03-10 | 2003-12-19 | Genentech Inc | Novel polypeptides and nucleic acids with homology to cornichon |
AU5203199A (en) | 1998-05-26 | 1999-12-13 | Procter & Gamble Company, The | Chimeric molecules comprising an extracellular ligand binding domain of a receptor and an ige fc or constant region, and their use in an assay system |
AU4411699A (en) * | 1998-06-05 | 1999-12-20 | Human Genome Sciences, Inc. | Interferon receptor hkaef92 |
EP1141008A1 (de) * | 1998-12-31 | 2001-10-10 | Millennium Pharmaceuticals, Inc. | Cytokinin klasse ii rezeptor-ähnliche proteine und für diese kodierende nukleinsäuren |
DK1246846T3 (da) | 1999-12-23 | 2008-12-08 | Zymogenetics Inc | Oplöselig interleukin-20-receptor |
EP2295079A3 (de) | 1999-12-23 | 2011-03-23 | ZymoGenetics, L.L.C. | Verfahren zur Behandlung von Entzündungen |
-
2000
- 2000-12-22 DK DK00986743T patent/DK1246846T3/da active
- 2000-12-22 AT AT00986743T patent/ATE407950T1/de active
- 2000-12-22 UA UA2002075992A patent/UA84830C2/uk unknown
- 2000-12-22 DE DE60040240T patent/DE60040240D1/de not_active Expired - Lifetime
- 2000-12-22 RU RU2002119563/13A patent/RU2279441C2/ru not_active IP Right Cessation
- 2000-12-22 EP EP00986743A patent/EP1246846B1/de not_active Expired - Lifetime
- 2000-12-22 DE DE60045139T patent/DE60045139D1/de not_active Expired - Lifetime
- 2000-12-22 CA CA002395539A patent/CA2395539C/en not_active Expired - Fee Related
- 2000-12-22 EP EP07012370A patent/EP1857466B1/de not_active Expired - Lifetime
- 2000-12-22 AT AT07012370T patent/ATE485306T1/de not_active IP Right Cessation
- 2000-12-22 AU AU22925/01A patent/AU783473B2/en not_active Ceased
- 2000-12-22 WO PCT/US2000/035307 patent/WO2001046232A2/en active IP Right Grant
- 2000-12-22 JP JP2001547141A patent/JP4741139B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2395539C (en) | 2009-08-25 |
UA84830C2 (uk) | 2008-12-10 |
DE60040240D1 (de) | 2008-10-23 |
EP1246846A2 (de) | 2002-10-09 |
EP1246846B1 (de) | 2008-09-10 |
AU783473B2 (en) | 2005-10-27 |
WO2001046232A3 (en) | 2002-02-21 |
JP4741139B2 (ja) | 2011-08-03 |
JP2003517846A (ja) | 2003-06-03 |
WO2001046232A2 (en) | 2001-06-28 |
RU2002119563A (ru) | 2004-03-27 |
ATE407950T1 (de) | 2008-09-15 |
RU2279441C2 (ru) | 2006-07-10 |
EP1857466A2 (de) | 2007-11-21 |
EP1857466A3 (de) | 2008-02-13 |
DK1246846T3 (da) | 2008-12-08 |
ATE485306T1 (de) | 2010-11-15 |
EP1857466B1 (de) | 2010-10-20 |
CA2395539A1 (en) | 2001-06-28 |
AU2292501A (en) | 2001-07-03 |
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