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DE60034568D1 - Zusammensetzungen mit verzögerter freigabe, verfahren zu deren herstellung und verwendung - Google Patents

Zusammensetzungen mit verzögerter freigabe, verfahren zu deren herstellung und verwendung

Info

Publication number
DE60034568D1
DE60034568D1 DE60034568T DE60034568T DE60034568D1 DE 60034568 D1 DE60034568 D1 DE 60034568D1 DE 60034568 T DE60034568 T DE 60034568T DE 60034568 T DE60034568 T DE 60034568T DE 60034568 D1 DE60034568 D1 DE 60034568D1
Authority
DE
Germany
Prior art keywords
release compositions
salt
production
lactic acid
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60034568T
Other languages
English (en)
Other versions
DE60034568T2 (de
Inventor
Yasutaka Igari
Yoshio Hata
Kazumichi Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of DE60034568D1 publication Critical patent/DE60034568D1/de
Application granted granted Critical
Publication of DE60034568T2 publication Critical patent/DE60034568T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polyesters Or Polycarbonates (AREA)
DE60034568T 1999-07-15 2000-07-13 Zusammensetzungen mit verzögerter freigabe, verfahren zu deren herstellung und verwendung Expired - Fee Related DE60034568T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP20188799 1999-07-15
JP20188799 1999-07-15
PCT/JP2000/004683 WO2001005380A1 (fr) 1999-07-15 2000-07-13 Compositions a liberation lente, techniques de production et methodes d'utilisation

Publications (2)

Publication Number Publication Date
DE60034568D1 true DE60034568D1 (de) 2007-06-06
DE60034568T2 DE60034568T2 (de) 2008-01-03

Family

ID=16448493

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60034568T Expired - Fee Related DE60034568T2 (de) 1999-07-15 2000-07-13 Zusammensetzungen mit verzögerter freigabe, verfahren zu deren herstellung und verwendung

Country Status (21)

Country Link
US (2) US7265157B1 (de)
EP (1) EP1197208B1 (de)
KR (1) KR20020012312A (de)
CN (1) CN1361685A (de)
AT (1) ATE360413T1 (de)
AU (1) AU5853000A (de)
BR (1) BR0012400A (de)
CA (1) CA2378714A1 (de)
CZ (1) CZ2002114A3 (de)
DE (1) DE60034568T2 (de)
HK (1) HK1042237A1 (de)
HU (1) HUP0202880A3 (de)
IL (1) IL147417A0 (de)
MX (1) MXPA02000461A (de)
NO (1) NO20020084L (de)
NZ (1) NZ516466A (de)
PL (1) PL352499A1 (de)
RU (1) RU2002103718A (de)
SK (1) SK342002A3 (de)
WO (1) WO2001005380A1 (de)
ZA (1) ZA200200347B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1048301A4 (de) 1998-01-16 2005-03-09 Takeda Chemical Industries Ltd Zusammensetzungen mit verzögerter wirkstoffabgabe, verfahren zu ihrer herstellung und ihre verwendung
DE69923795T2 (de) 1998-12-15 2006-03-16 Takeda Pharmaceutical Co. Ltd. Verfahren zur Herstellung biologisch-abbaubarer Polyester
PT1310517E (pt) 2000-08-07 2006-05-31 Wako Pure Chem Ind Ltd Polimero de acido lactico e processo para a sua producao
US20040116522A1 (en) * 2001-03-30 2004-06-17 Yutaka Yamagata Medicinal solutions
CA2444727A1 (en) * 2001-04-25 2002-11-07 Takeda Chemical Industries, Ltd. Agents for preventing postoperative recurrence of premenopausal breast cancer
US6693134B2 (en) * 2001-05-29 2004-02-17 Chemokine Therapeutics Corporation Bicyclic aromatic chemokine receptor ligands
TW200526267A (en) * 2001-06-29 2005-08-16 Takeda Chemical Industries Ltd Controlled release composition and method of producing the same
KR100994658B1 (ko) * 2001-12-26 2010-11-16 다케다 야쿠힌 고교 가부시키가이샤 신규 마이크로스피어 및 이들의 제조 방법
CN1662260B (zh) 2002-06-25 2010-04-28 武田药品工业株式会社 缓释组合物的制备方法
EP2444069B1 (de) * 2003-07-23 2019-06-05 Evonik Corporation Zusammensetzung mit kontrollierter Freisetzung
US20050064045A1 (en) * 2003-09-18 2005-03-24 Sheng-Ping Zhong Injectable therapeutic formulations
US7906125B2 (en) 2003-09-18 2011-03-15 Boston Scientific Scimed, Inc. Solid or semi-solid therapeutic formulations
TW200529890A (en) 2004-02-10 2005-09-16 Takeda Pharmaceutical Sustained-release preparations
EP1679065A1 (de) 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Zubereitung mit kontrollierter Freisetzung von Interferon auf PEGT/PBT-Block-Copolymer-Basis
US8263109B2 (en) 2005-05-09 2012-09-11 Boston Scientific Scimed, Inc. Injectable bulking compositions
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
US20070149443A1 (en) * 2005-12-13 2007-06-28 Byron Rubin Methods of treating obesity using enterostatin
WO2007070563A2 (en) * 2005-12-13 2007-06-21 Harkness Pharmaceuticals, Inc. Stable solid forms of enterostatin
JP2009542813A (ja) * 2006-07-11 2009-12-03 ハルクネスス プハルマセウティカルス，インコーポレイテッド 飽食因子を使用して肥満を治療する方法
US7858663B1 (en) * 2007-10-31 2010-12-28 Pisgah Laboratories, Inc. Physical and chemical properties of thyroid hormone organic acid addition salts
NZ577281A (en) 2006-12-18 2011-12-22 Takeda Pharmaceutical Sustained-release composition and method for producing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022786A1 (en) 1995-01-23 1996-08-01 Takeda Chemical Industries, Ltd. Sustained-release preparation and use
EP0839525B1 (de) 1996-10-31 2004-08-04 Takeda Chemical Industries, Ltd. Zubereitung mit verzögerter Freisetzung
AU5678398A (en) 1997-01-29 1998-08-18 Takeda Chemical Industries Ltd. Sustained-release microspheres, their production and use
EP1048301A4 (de) * 1998-01-16 2005-03-09 Takeda Chemical Industries Ltd Zusammensetzungen mit verzögerter wirkstoffabgabe, verfahren zu ihrer herstellung und ihre verwendung
JPH11269094A (ja) * 1998-01-16 1999-10-05 Takeda Chem Ind Ltd 徐放性組成物、その製造法および用途
DE69923795T2 (de) * 1998-12-15 2006-03-16 Takeda Pharmaceutical Co. Ltd. Verfahren zur Herstellung biologisch-abbaubarer Polyester

Also Published As

Publication number Publication date
NZ516466A (en) 2003-02-28
NO20020084D0 (no) 2002-01-08
ZA200200347B (en) 2003-03-26
PL352499A1 (en) 2003-08-25
HUP0202880A2 (hu) 2003-01-28
EP1197208A1 (de) 2002-04-17
MXPA02000461A (es) 2002-07-30
CZ2002114A3 (cs) 2002-04-17
IL147417A0 (en) 2002-08-14
HK1042237A1 (zh) 2002-08-09
SK342002A3 (en) 2002-05-09
AU5853000A (en) 2001-02-05
EP1197208A4 (de) 2004-06-30
KR20020012312A (ko) 2002-02-15
US7265157B1 (en) 2007-09-04
RU2002103718A (ru) 2003-10-10
EP1197208B1 (de) 2007-04-25
DE60034568T2 (de) 2008-01-03
CN1361685A (zh) 2002-07-31
WO2001005380A1 (fr) 2001-01-25
HUP0202880A3 (en) 2003-04-28
NO20020084L (no) 2002-03-14
US20080014237A1 (en) 2008-01-17
ATE360413T1 (de) 2007-05-15
BR0012400A (pt) 2002-05-21
CA2378714A1 (en) 2001-01-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee