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DE60023476D1 - Kombination von doctaxel und rhumab her2 zür krebsbehandlung - Google Patents

Kombination von doctaxel und rhumab her2 zür krebsbehandlung

Info

Publication number
DE60023476D1
DE60023476D1 DE60023476T DE60023476T DE60023476D1 DE 60023476 D1 DE60023476 D1 DE 60023476D1 DE 60023476 T DE60023476 T DE 60023476T DE 60023476 T DE60023476 T DE 60023476T DE 60023476 D1 DE60023476 D1 DE 60023476D1
Authority
DE
Germany
Prior art keywords
rhumab her2
doctaxel
combination
cancer treatment
docetaxel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60023476T
Other languages
English (en)
Other versions
DE60023476T2 (de
Inventor
Charles Le Vogel
E Bellet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22435924&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60023476(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of DE60023476D1 publication Critical patent/DE60023476D1/de
Application granted granted Critical
Publication of DE60023476T2 publication Critical patent/DE60023476T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Drying Of Gases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
DE60023476T 1999-04-09 2000-04-07 Kombination von doctaxel und rhumab her2 zur krebsbehandlung Expired - Lifetime DE60023476T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12856499P 1999-04-09 1999-04-09
US128564P 1999-04-09
PCT/US2000/009247 WO2000061185A1 (en) 1999-04-09 2000-04-07 Docetaxel in combination with rhumab her2 for the treatment of cancers

Publications (2)

Publication Number Publication Date
DE60023476D1 true DE60023476D1 (de) 2005-12-01
DE60023476T2 DE60023476T2 (de) 2006-07-06

Family

ID=22435924

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60023476T Expired - Lifetime DE60023476T2 (de) 1999-04-09 2000-04-07 Kombination von doctaxel und rhumab her2 zur krebsbehandlung

Country Status (22)

Country Link
US (1) US6333348B1 (de)
EP (1) EP1169059B1 (de)
JP (2) JP2003512298A (de)
KR (1) KR100695383B1 (de)
CN (1) CN1191859C (de)
AT (1) ATE307608T1 (de)
AU (1) AU777661B2 (de)
BR (1) BR0009647A (de)
CA (1) CA2368369C (de)
CZ (1) CZ296373B6 (de)
DE (1) DE60023476T2 (de)
DK (1) DK1169059T3 (de)
EA (1) EA006097B1 (de)
ES (1) ES2248070T3 (de)
HK (2) HK1043313A1 (de)
HU (1) HU226672B1 (de)
MX (1) MXPA01010138A (de)
NO (1) NO332619B1 (de)
NZ (1) NZ515337A (de)
TR (1) TR200102845T2 (de)
WO (1) WO2000061185A1 (de)
ZA (1) ZA200107771B (de)

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US6406693B1 (en) * 1998-07-13 2002-06-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
US6818213B1 (en) * 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
BR9911882A (pt) 1998-07-13 2005-02-15 Univ Texas Processo de tratamento de câncer empregando anticorpos a aminofosfolipìdios
US7067109B1 (en) * 1998-07-13 2006-06-27 Board Of Regents, The University Of Texas System Cancer treatment kits comprising therapeutic conjugates that bind to aminophospholipids
US6333348B1 (en) * 1999-04-09 2001-12-25 Aventis Pharma S.A. Use of docetaxel for treating cancers
US20040013667A1 (en) * 1999-06-25 2004-01-22 Genentech, Inc. Treatment with anti-ErbB2 antibodies
US6949245B1 (en) 1999-06-25 2005-09-27 Genentech, Inc. Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
US7041292B1 (en) 1999-06-25 2006-05-09 Genentech, Inc. Treating prostate cancer with anti-ErbB2 antibodies
BR0012195A (pt) * 1999-06-25 2002-07-23 Genentech Inc Método para tratar câncer de próstata num ser humano, artigo de fabricação e uso de um anticorpo que liga erbb2
GB9917012D0 (en) * 1999-07-20 1999-09-22 Pharmacia & Upjohn Spa Combined preparations comprising antitumor agents
KR20090024308A (ko) 1999-08-27 2009-03-06 제넨테크, 인크. 항-ＥｒｂＢ2 항체 투여 치료 방법
PL400669A1 (pl) 2000-05-19 2012-11-05 Genentech, Inc. Genowa próba wykrywania odpowiedzi na antagoniste ErbB dla poprawienia prawdopodobienstwa i skutecznosci leczenia raka
AU2002232413A1 (en) * 2000-11-21 2002-06-03 Cell Pathways, Inc. Method for treating neoplasia by administering an anti-her2 antibody and a cgmp-specific phosphodiesterase inhibitor
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US7714109B2 (en) * 2002-07-15 2010-05-11 Board Of Regents, The University Of Texas System Combinations and kits for cancer treatment using selected antibodies to aminophospholipids
US7622118B2 (en) * 2002-07-15 2009-11-24 Board Of Regents, The University Of Texas System Cancer treatment methods using selected antibodies to aminophospholipids
US7625563B2 (en) * 2002-07-15 2009-12-01 Board Of Regents, The University Of Texas System Cancer treatment methods using selected immunoconjugates for binding to aminophospholipids
CA2491310C (en) * 2002-07-15 2015-10-06 Board Of Regents, The University Of Texas System Compositions comprising cell-impermeant duramycin derivatives
US7615223B2 (en) * 2002-07-15 2009-11-10 Board Of Regents, The University Of Texas System Selected immunoconjugates for binding to aminophospholipids
US7247303B2 (en) * 2002-07-15 2007-07-24 Board Of Regents, The University Of Texas System Selected antibody CDRs for binding to aminophospholipids
US7572448B2 (en) * 2002-07-15 2009-08-11 Board Of Regents, The University Of Texas System Combined cancer treatment methods using selected antibodies to aminophospholipids
US7678386B2 (en) * 2002-07-15 2010-03-16 Board Of Regents The University Of Texas Liposomes coated with selected antibodies that bind to aminophospholipids
EP1572972A4 (de) * 2002-11-21 2007-11-21 Genentech Inc Therapie nichtmaligner krankheiten oder störungen mit anti-erbb2-antikörpern
US7989490B2 (en) * 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
JP2008528486A (ja) 2005-01-21 2008-07-31 ジェネンテック・インコーポレーテッド Ｈｅｒ抗体の一定投薬
ZA200706247B (en) * 2005-02-09 2008-11-26 Genentech Inc Inhibiting HER2 shedding with matrix metalloprotease antagonists
RU2404806C2 (ru) 2005-02-23 2010-11-27 Дженентек, Инк. Продление времени до прогрессирования заболевания или продолжительности жизни у онкологических больных с применением ингибиторов димеризации her
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Ｈｅｒｃｅｐｔｉｎ（登録商標）補助療法
US20070172844A1 (en) * 2005-09-28 2007-07-26 University Of South Florida Individualized cancer treatments
EP1913958B1 (de) * 2006-08-03 2009-12-23 Sanofi-Aventis Antitumorale Zusammensetzungen enthaltend Acetylcyclopropyl Docetaxel und Trastuzumab
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US9551033B2 (en) 2007-06-08 2017-01-24 Genentech, Inc. Gene expression markers of tumor resistance to HER2 inhibitor treatment
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EP2133433A1 (de) * 2008-06-09 2009-12-16 Centre Georges François Leclerc Verfahren zur Vorhersage der Reaktion auf eine Behandlung mit einem Antikörper gegen HER2
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
US20110286960A1 (en) * 2008-11-02 2011-11-24 Optimata Ltd. Cancer therapy by docetaxel and granulocyte colony-stimulating factor (g-csf)
MD35Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
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CN102356092B (zh) 2009-03-20 2014-11-05 霍夫曼-拉罗奇有限公司 双特异性抗-her抗体
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US9327023B2 (en) 2011-10-25 2016-05-03 The Regents Of The University Of Michigan HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
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US6333348B1 (en) * 1999-04-09 2001-12-25 Aventis Pharma S.A. Use of docetaxel for treating cancers

Also Published As

Publication number Publication date
HK1046093A1 (en) 2002-12-27
CA2368369A1 (en) 2000-10-19
JP2003512298A (ja) 2003-04-02
EA006097B1 (ru) 2005-08-25
EP1169059B1 (de) 2005-10-26
ATE307608T1 (de) 2005-11-15
HU226672B1 (en) 2009-06-29
ZA200107771B (en) 2002-09-20
CZ296373B6 (cs) 2006-03-15
CZ20013614A3 (cs) 2002-07-17
ES2248070T3 (es) 2006-03-16
NO332619B1 (no) 2012-11-19
HK1046093B (zh) 2005-10-28
NO20014842D0 (no) 2001-10-04
DE60023476T2 (de) 2006-07-06
US6333348B1 (en) 2001-12-25
WO2000061185A1 (en) 2000-10-19
NZ515337A (en) 2003-10-31
EP1169059A1 (de) 2002-01-09
KR100695383B1 (ko) 2007-03-15
CN1191859C (zh) 2005-03-09
HK1043313A1 (zh) 2002-09-13
HUP0201459A2 (en) 2002-09-28
CN1350464A (zh) 2002-05-22
CA2368369C (en) 2014-03-25
NO20014842L (no) 2001-10-04
TR200102845T2 (tr) 2002-01-21
AU4332700A (en) 2000-11-14
KR20020007358A (ko) 2002-01-26
EA200101064A1 (ru) 2002-04-25
AU777661B2 (en) 2004-10-28
HUP0201459A3 (en) 2003-04-28
DK1169059T3 (da) 2006-02-27
BR0009647A (pt) 2002-01-08
JP2012136535A (ja) 2012-07-19
MXPA01010138A (es) 2003-07-14

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