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DE3689056D1 - Verfahren und Zusammensetzung zur Herstellung von Liposomen. - Google Patents

Verfahren und Zusammensetzung zur Herstellung von Liposomen.

Info

Publication number
DE3689056D1
DE3689056D1 DE86306014T DE3689056T DE3689056D1 DE 3689056 D1 DE3689056 D1 DE 3689056D1 DE 86306014 T DE86306014 T DE 86306014T DE 3689056 T DE3689056 T DE 3689056T DE 3689056 D1 DE3689056 D1 DE 3689056D1
Authority
DE
Germany
Prior art keywords
liposomes
composition
production
preliposome
liposome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE86306014T
Other languages
English (en)
Other versions
DE3689056T2 (de
Inventor
John Y Park
Shurl A Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
SmithKline Beecham Corp
Original Assignee
GlaxoSmithKline LLC
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25067952&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3689056(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by GlaxoSmithKline LLC, SmithKline Beecham Corp filed Critical GlaxoSmithKline LLC
Publication of DE3689056D1 publication Critical patent/DE3689056D1/de
Application granted granted Critical
Publication of DE3689056T2 publication Critical patent/DE3689056T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Materials For Medical Uses (AREA)
DE86306014T 1985-08-07 1986-08-05 Verfahren und Zusammensetzung zur Herstellung von Liposomen. Expired - Fee Related DE3689056T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76348485A 1985-08-07 1985-08-07

Publications (2)

Publication Number Publication Date
DE3689056D1 true DE3689056D1 (de) 1993-10-28
DE3689056T2 DE3689056T2 (de) 1994-01-27

Family

ID=25067952

Family Applications (1)

Application Number Title Priority Date Filing Date
DE86306014T Expired - Fee Related DE3689056T2 (de) 1985-08-07 1986-08-05 Verfahren und Zusammensetzung zur Herstellung von Liposomen.

Country Status (20)

Country Link
EP (1) EP0211647B1 (de)
JP (1) JP2511417B2 (de)
KR (1) KR900007185B1 (de)
CN (1) CN1027491C (de)
AT (1) ATE94754T1 (de)
AU (1) AU601154B2 (de)
CA (1) CA1280975C (de)
DE (1) DE3689056T2 (de)
DK (1) DK362786A (de)
ES (1) ES8801118A1 (de)
FI (1) FI863227L (de)
GR (1) GR862020B (de)
HK (1) HK1004530A1 (de)
HU (1) HU198836B (de)
IE (1) IE61445B1 (de)
IL (1) IL79114A (de)
NO (1) NO863176L (de)
NZ (1) NZ216768A (de)
PT (1) PT83130B (de)
ZA (1) ZA864541B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL79114A (en) * 1985-08-07 1990-09-17 Allergan Pharma Method and composition for making liposomes
US4883670A (en) * 1986-10-23 1989-11-28 Arval S.P.A. Cosmetic preparations containing ubidecarenones
IT1214540B (it) * 1986-10-23 1990-01-18 Vincenzo Zappia Mario De Rosa Formulazioni idrosolubili di ubidecarenoni, procedimento per laloro preparazione e composizioni farmaceutiche che li compongono.
JPH03500652A (ja) * 1987-10-19 1991-02-14 ザ　リポソーム　カンパニー，インコーポレイテッド リポソーム組成物の水性製剤
FR2631234B1 (fr) * 1988-05-10 1990-09-14 Dior Christian Parfums Composition cosmetique ou dermatologique, notamment a action amincissante ou anti-cellulitique contenant des extraits de cola sous forme libre ou sous forme liposomale
JP2786482B2 (ja) * 1988-06-29 1998-08-13 第一製薬株式会社 脂質膜構造体
BE1001869A3 (fr) * 1988-10-12 1990-04-03 Franz Legros Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US5741513A (en) * 1990-02-08 1998-04-21 A. Natterman & Cie. Gmbh Alcoholic aqueous gel-like phospholipid composition, its use and topical preparations containing it
JP3218637B2 (ja) * 1990-07-26 2001-10-15 大正製薬株式会社 安定なリポソーム水懸濁液
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
JP3765579B2 (ja) * 1990-08-24 2006-04-12 イーデーエーアー アーゲー 作用物質投与用超微小滴状調剤
DE4038075C1 (en) * 1990-11-29 1992-03-19 B. Braun Melsungen Ag, 3508 Melsungen, De Encapsulating solid or liq. lipophilic agents - comprises mixing hydration medium with phospholipid increasing temp. to above soln. phase change temp. and adding remaining medium
CA2087691A1 (en) * 1992-01-23 1993-07-24 Peter Critchley Cosmetic compositon
GB9224502D0 (en) * 1992-11-23 1993-01-13 New Roger R C Method of preparing a lipid-containing formulation
EP0684838A1 (de) * 1993-02-19 1995-12-06 Smithkline Beecham Corporation 3-0-deacylierte monophoshoryl lipid a enthaltende influenzaimpfstoffzusammensetzungen
DK0616799T3 (da) * 1993-03-24 2000-09-18 Collaborative Lab Inc Kosmetisk applikationssystem for salicylsyre og fremgangsmåde til fremstilling heraf
CA2120197A1 (en) * 1993-04-02 1994-10-03 Kenji Endo Stable aqueous dispersions containing liposomes
JPH0757826A (ja) * 1993-08-18 1995-03-03 Nec Corp 端子台
TW520294B (en) * 1998-01-08 2003-02-11 Res Dev Foundation Stabilization of lipid: DNA formulations during nebulization
US6375980B1 (en) * 1998-01-08 2002-04-23 Research Development Foundation Stabilization of lipid:DNA formulations during nebulization
MXPA01006424A (es) 1998-12-23 2002-06-04 Idea Ag Formulacion mejorada para aplicacion topica no invasiva in vivo.
ATE216875T1 (de) 1999-01-27 2002-05-15 Idea Ag Nichtinvasive impfung durch die haut
EP1031347B1 (de) 1999-01-27 2002-04-17 Idea Ag Transnasaler Transport bzw. Impfung mit hochadaptierbaren Trägern
WO2001001962A1 (en) 1999-07-05 2001-01-11 Idea Ag. A method for the improvement of transport across adaptable semi-permeable barriers
US6248353B1 (en) * 1999-12-10 2001-06-19 Dade Behring Inc. Reconstitution of purified membrane proteins into preformed liposomes
EP1138310A1 (de) * 2000-03-28 2001-10-04 Primacare S.A. Pro-liposomen
ES2260321T3 (es) 2000-12-07 2006-11-01 Universiteit Utrecht Holding B.V. Composicion para el tratamiento de transtornos inflamatorios.
US6610322B1 (en) 2000-12-20 2003-08-26 Brian Charles Keller Self forming, thermodynamically stable liposomes and their applications
US20040105881A1 (en) 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
GB0404993D0 (en) * 2004-03-05 2004-04-07 Univ Liverpool John Moores Method and apparatus for producing carrier complexes
JP5137256B2 (ja) * 2005-03-31 2013-02-06 ユニリーバー・ナームローゼ・ベンノートシヤープ 皮膚効果剤の増強された送達
JP5484059B2 (ja) * 2006-10-06 2014-05-07 エスシーアイエル テクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング 脊髄核インプラント
JP5112673B2 (ja) * 2006-10-16 2013-01-09 株式会社コーセー セラミド含有組成物及びこれを配合する皮膚外用剤
EP2667853A4 (de) * 2011-01-25 2014-08-20 Procter & Gamble Liposom- und körperpflegezusammensetzung damit
US8986732B2 (en) 2013-08-12 2015-03-24 Helix Biopharma Corporation Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery
US10159646B2 (en) * 2013-08-12 2018-12-25 Altum-Avro Pharma Partnership Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery
IT201700086879A1 (it) * 2017-07-28 2019-01-28 Univ Degli Studi Cagliari Vescicole lipidiche a doppio strato contenenti adrenalina, per uso nel trattamento delle emergenze cardiache
CN109224879B (zh) * 2018-09-17 2021-04-27 南京工业大学 一种cha分子筛膜的制备方法
CN113995852B (zh) * 2021-11-08 2024-01-30 河北大学 Arg-脂质体微囊、微囊包封的鱼精蛋白-siRNA复合体及其制备方法和应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK116528A (de) * 1966-09-30
US3932657A (en) * 1973-11-12 1976-01-13 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome encapsulation of chelating agents
US3957971A (en) * 1974-07-29 1976-05-18 Lever Brothers Company Moisturizing units and moisturizing compositions containing the same
AT356278B (de) * 1976-07-12 1980-04-25 Hoffmann La Roche Verfahren zur herstellung von injektions- loesungen
JPS5323872A (en) * 1976-08-17 1978-03-04 Takeda Chem Ind Ltd Preparation of microcapsule
DE2656333C2 (de) * 1976-12-13 1985-08-08 Karl Prof. Dr.med. 7302 Ostfildern Theurer Verfahren zur Herstellung von Liposomen, welche Arzneistoffe enthalten
IT1110989B (it) * 1979-01-19 1986-01-13 Erba Farmitalia Forme farmaceutiche costitutite da liposomi e procedimenti relativi
DE2856333C2 (de) * 1978-12-27 1983-09-22 A. Nattermann & Cie GmbH, 5000 Köln Oral einnehmbare Arzneimittel mit entzündungshemmender Wirkung
US4174296A (en) * 1978-12-04 1979-11-13 American Lecithin Company Water soluble lecithin composition
US4528193A (en) * 1978-12-27 1985-07-09 A. Natterman & Cie. Gmbh Inflammation-preventing pharmaceutical composition of oral administration
DE2914789A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Injizierbare arzneimittel mit entzuendungshemmender wirkung
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
JPS574913A (en) * 1980-06-11 1982-01-11 Green Cross Corp:The Urokinase preparation for oral administration
JPS5746921A (en) * 1980-09-02 1982-03-17 Green Cross Corp:The Oral preparation of human blood coagulation factor
IL64397A0 (en) * 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
WO1983003383A1 (en) * 1982-03-29 1983-10-13 Liposome Co Inc Stable plurilamellar vesicles
EP0102324A3 (de) * 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
SE8206744D0 (sv) * 1982-11-26 1982-11-26 Fluidcarbon International Ab Preparat for kontrollerad avgivning av substanser
FR2540381B1 (fr) * 1983-02-08 1986-05-30 Dior Sa Parfums Christian Procede pour stimuler la croissance des cellules; composition cosmetique, pharmaceutique et composition complementaire pour milieu de culture cellulaire appliquant ce procede
JPS607934A (ja) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソ−ムの製造方法
JPS607932A (ja) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソーム懸濁液およびその製法
IL79114A (en) * 1985-08-07 1990-09-17 Allergan Pharma Method and composition for making liposomes

Also Published As

Publication number Publication date
EP0211647B1 (de) 1993-09-22
ES8801118A1 (es) 1987-12-16
ZA864541B (en) 1987-02-25
JPS6242733A (ja) 1987-02-24
IE862103L (en) 1987-02-07
FI863227L (fi) 1987-02-08
IE61445B1 (en) 1994-11-02
KR900007185B1 (ko) 1990-09-29
AU601154B2 (en) 1990-09-06
PT83130B (pt) 1989-03-30
NO863176D0 (no) 1986-08-06
ES556651A0 (es) 1987-12-16
HK1004530A1 (en) 1998-11-27
AU5914186A (en) 1987-12-24
PT83130A (en) 1986-09-01
IL79114A (en) 1990-09-17
NZ216768A (en) 1989-11-28
DE3689056T2 (de) 1994-01-27
HU198836B (en) 1989-12-28
JP2511417B2 (ja) 1996-06-26
EP0211647A1 (de) 1987-02-25
CA1280975C (en) 1991-03-05
FI863227A0 (fi) 1986-08-06
IL79114A0 (en) 1986-09-30
CN1027491C (zh) 1995-01-25
KR880002508A (ko) 1988-05-09
NO863176L (no) 1987-02-09
DK362786D0 (da) 1986-07-30
GR862020B (en) 1986-12-24
HUT43487A (en) 1987-11-30
ATE94754T1 (de) 1993-10-15
DK362786A (da) 1987-02-08
CN86104874A (zh) 1987-02-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee