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DE3468688D1 - Peptides and their use in therapy - Google Patents

Peptides and their use in therapy

Info

Publication number
DE3468688D1
DE3468688D1 DE8484306950T DE3468688T DE3468688D1 DE 3468688 D1 DE3468688 D1 DE 3468688D1 DE 8484306950 T DE8484306950 T DE 8484306950T DE 3468688 T DE3468688 T DE 3468688T DE 3468688 D1 DE3468688 D1 DE 3468688D1
Authority
DE
Germany
Prior art keywords
phe
cys
peptides
therapy
thr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484306950T
Other languages
English (en)
Inventor
David H Coy
William A Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
Original Assignee
Tulane University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tulane University filed Critical Tulane University
Application granted granted Critical
Publication of DE3468688D1 publication Critical patent/DE3468688D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE8484306950T 1983-10-11 1984-10-11 Peptides and their use in therapy Expired DE3468688D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/540,380 US4485101A (en) 1983-10-11 1983-10-11 Peptides

Publications (1)

Publication Number Publication Date
DE3468688D1 true DE3468688D1 (en) 1988-02-18

Family

ID=24155205

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484306950T Expired DE3468688D1 (en) 1983-10-11 1984-10-11 Peptides and their use in therapy

Country Status (7)

Country Link
US (1) US4485101A (de)
EP (1) EP0142272B1 (de)
JP (1) JPH0635479B2 (de)
AT (1) ATE31931T1 (de)
CA (1) CA1265899A (de)
DE (1) DE3468688D1 (de)
ZA (1) ZA847960B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863899A (en) * 1983-05-09 1989-09-05 Todaro George J Biologically active polypeptides
US5240912A (en) * 1983-05-09 1993-08-31 Todaro George J Transforming growth factor (TGF) peptides
JPS6034997A (ja) * 1983-05-09 1985-02-22 ジヨージ、ジヨセフ、トダロ 生物学的活性ポリペプチド類
US4904642A (en) * 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4853371A (en) * 1986-06-17 1989-08-01 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
GB8620035D0 (en) * 1986-08-18 1986-10-01 Sandoz Ltd Organic compounds
US4871717A (en) * 1987-01-07 1989-10-03 Administrators Of The Tulane Educational Fund Peptides
GB2239178B (en) * 1987-07-10 1991-11-27 Sandoz Ltd Somatostatin analogues for the treatment of breast cancer
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
GB8813160D0 (en) * 1988-06-03 1988-07-06 Soc D Etudes Prod Chimique Therapeutic methods
US5633263A (en) * 1989-04-26 1997-05-27 The Administrators Of The Tulane Educational Fund Linear somatostatin analogs
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
ATE140237T1 (de) * 1989-12-08 1996-07-15 Univ Tulane Oktapeptidanaloge von somatostatin mit threonin in position 6
CA2079896A1 (en) * 1991-02-08 1992-08-09 Arthur E. Bogden Method of treating benign and malignant proliferative skin disease
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US5620675A (en) * 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
EP0981364B1 (de) * 1997-05-13 2006-03-01 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Methoden und zusammensetzungen zur behandlung der hyperlipidämie
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
CA2289499C (en) * 1997-05-13 2010-02-23 Michael Anthony Cawthorne Somatostatin and somatostatin agonists for treating insulin insensitivity and syndrome x
PT981363E (pt) 1997-05-13 2003-12-31 Conseils De Rec Appl Scient S Somatostatina e agonistas da somatostatina para reduzir o peso corporal
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
CA2246791A1 (en) * 1998-09-01 2000-03-01 Alison Buchan Treatment of endothelium with somatostatin analogues
JP2002089791A (ja) * 2000-09-14 2002-03-27 Sumitomo Precision Prod Co Ltd 液化ガス気化装置
JP2002340296A (ja) * 2001-05-16 2002-11-27 Sumitomo Precision Prod Co Ltd 液化ガス気化・加熱装置
MXPA03011321A (es) 2001-06-08 2004-12-06 Conseils De Rech S Et D Aplica Analogos quimericos de somatostatina-dopamina.
EP1490625B1 (de) * 2002-03-29 2011-08-31 Excelerate Energy Limited Partnership Verfahren und vorrichtung für die wiederverdampfung von verflüssigtem erdgas an bord eines transportschiffes
EP1610805A2 (de) * 2003-03-10 2006-01-04 Biogen Idec Inc. Thiol-vermittelte wirkstoffanbindung an targeting-peptide
RU2361876C2 (ru) 2003-04-22 2009-07-20 Сосьете Де Консей Де Решерш Э Д`Аппликасьон Сьентифик С.А.С. Пептидные векторы
FI20031454A0 (fi) 2003-10-06 2003-10-06 Juvantia Pharma Ltd Oy Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja
JP2008540618A (ja) * 2005-05-18 2008-11-20 ブルスター，ジークフリート ソマトスタチン受容体サブタイプ１及び／又は４に選択的なペプチド模倣薬
AU2011255490B2 (en) 2010-05-20 2015-07-23 Excelerate Energy Limited Partnership Systems and methods for treatment of LNG cargo tanks
US20160129089A1 (en) 2013-06-13 2016-05-12 Antisense Therapeutics Ltd Combination therapy
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
US20170121385A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions
JP7099717B2 (ja) 2019-09-30 2022-07-12 株式会社理研バイオ ソマトスタチン受容体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2416048A1 (de) * 1974-04-03 1975-10-30 Hoechst Ag Neue peptide mit biologischer wirkung
DE2519656A1 (de) * 1974-05-13 1975-11-27 Sandoz Ag Neue peptide und verfahren zu ihrer herstellung
DE2608336A1 (de) * 1975-03-11 1976-09-30 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
US4372884A (en) * 1975-08-06 1983-02-08 The Salk Institute For Biological Studies Pharmaceutically active peptides
US4133782A (en) * 1976-06-07 1979-01-09 The Salk Institute For Biological Studies Somatostatin analogs with dissociated biological activities
US4190575A (en) * 1977-12-27 1980-02-26 American Home Products Corporation Polypeptides related to somatostatin
GB1578402A (en) * 1977-02-22 1980-11-05 American Home Prod Somatostatin peptide analogues
US4211693A (en) * 1977-09-20 1980-07-08 The Salk Institute For Biological Studies Peptides with para-substituted phenylalanine
CA1107273A (en) * 1978-05-19 1981-08-18 Chester A. Meyers Somatostatin analogs having a substituted tryptophyl residue in position eight
US4215039A (en) * 1979-02-15 1980-07-29 American Home Products Corporation Somatostatin analogues
US4209426A (en) * 1979-05-29 1980-06-24 American Home Products Corporation Polypeptides related to somatostatin
US4369179A (en) * 1979-12-14 1983-01-18 Ciba-Geigy Corporation Acylpeptides

Also Published As

Publication number Publication date
ZA847960B (en) 1985-06-26
JPH0635479B2 (ja) 1994-05-11
EP0142272A1 (de) 1985-05-22
US4485101A (en) 1984-11-27
EP0142272B1 (de) 1988-01-13
ATE31931T1 (de) 1988-01-15
CA1265899A (en) 1990-02-13
JPS60149599A (ja) 1985-08-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee