DE3461713D1 - Heterocyclic compounds, process for their preparation and medicines containing them - Google Patents
Heterocyclic compounds, process for their preparation and medicines containing themInfo
- Publication number
- DE3461713D1 DE3461713D1 DE8484400058T DE3461713T DE3461713D1 DE 3461713 D1 DE3461713 D1 DE 3461713D1 DE 8484400058 T DE8484400058 T DE 8484400058T DE 3461713 T DE3461713 T DE 3461713T DE 3461713 D1 DE3461713 D1 DE 3461713D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- heterocyclic compounds
- medicines containing
- substituted
- medicines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 229960004676 antithrombotic agent Drugs 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000002829 nitrogen Chemical class 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- -1 p is 0 or 1 and y=H Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Silicon Polymers (AREA)
- Peptides Or Proteins (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Earth Drilling (AREA)
- Instructional Devices (AREA)
- Materials For Medical Uses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8300454A FR2539417A1 (fr) | 1983-01-13 | 1983-01-13 | Nouveaux pyrrolo-1, 2 heterocycles, leur preparation et les medicaments qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3461713D1 true DE3461713D1 (en) | 1987-01-29 |
Family
ID=9284899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484400058T Expired DE3461713D1 (en) | 1983-01-13 | 1984-01-12 | Heterocyclic compounds, process for their preparation and medicines containing them |
Country Status (26)
Country | Link |
---|---|
US (2) | US4546100A (de) |
EP (1) | EP0118321B1 (de) |
JP (1) | JPS59134797A (de) |
KR (1) | KR910001284B1 (de) |
AT (1) | ATE24321T1 (de) |
AU (1) | AU562832B2 (de) |
BG (4) | BG40147A3 (de) |
CA (1) | CA1222514A (de) |
CS (1) | CS259516B2 (de) |
DD (1) | DD216022A5 (de) |
DE (1) | DE3461713D1 (de) |
DK (1) | DK13884A (de) |
ES (3) | ES8502122A1 (de) |
FI (1) | FI76578C (de) |
FR (1) | FR2539417A1 (de) |
GR (1) | GR81680B (de) |
HU (1) | HU194224B (de) |
IE (1) | IE56838B1 (de) |
IL (1) | IL70663A (de) |
MA (1) | MA20002A1 (de) |
NO (1) | NO167032C (de) |
NZ (1) | NZ206809A (de) |
PL (4) | PL142322B1 (de) |
PT (1) | PT77951B (de) |
SU (6) | SU1297730A3 (de) |
ZA (1) | ZA84234B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2557111B1 (fr) * | 1983-12-21 | 1986-04-11 | Rhone Poulenc Sante | Nouveaux derives ortho-condenses du pyrrole, leur preparation et les medicaments qui les contiennent |
GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
US5260451A (en) * | 1989-05-11 | 1993-11-09 | Merckle Gmbh | Substituted pyrrole compounds and use thereof in pharmaceutical compositions |
DE3915450A1 (de) * | 1989-05-11 | 1990-11-15 | Gerd Prof Dr Dannhardt | Substituierte pyrrolverbindungen und deren anwendung in der pharmazie |
JP3061631B2 (ja) * | 1989-10-11 | 2000-07-10 | 山之内製薬株式会社 | 新規なヘテロ環化合物およびその製造法 |
DE4419247A1 (de) * | 1994-06-01 | 1995-12-07 | Merckle Gmbh | Sulfonylierte Pyrrolizincarbonsäureamide und deren Anwendung in der Pharmazie |
DE4419246A1 (de) * | 1994-06-01 | 1995-12-07 | Merckle Gmbh | Heteroarylsubstituierte Pyrrolizinverbindungen und deren Anwendung in der Pharmazie |
FR2735476B1 (fr) * | 1995-06-14 | 1997-07-18 | Rhone Poulenc Rorer Sa | Nouvelle application de derives du pyrrole |
ATE369369T1 (de) | 1999-11-23 | 2007-08-15 | Merckle Gmbh | Antiinflammatorische oxo- und hydroxyderivative von pyrrolizinen und deren anwendung in der pharmazie |
DE10004157A1 (de) | 2000-02-01 | 2001-08-02 | Merckle Gmbh Chem Pharm Fabrik | 4-Pyridyl-und 2,4-Pyrimidinyl-substituierte Pyrrolderivate und ihre Anwendung in der Pharmazie |
US8424704B2 (en) * | 2004-06-02 | 2013-04-23 | X-Pert Paint Mixing Systems, Inc. | Self-cleaning lid for a paint container fluid pour spout |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1401707A (fr) * | 1963-07-03 | 1965-06-04 | Kodak Pathe | Nouveaux colorants, nouveaux composés intermédiaires servant à les préparer et produits photographiques les contenant |
BE649903A (de) * | 1963-07-03 | |||
US3642807A (en) * | 1970-06-18 | 1972-02-15 | Schering Corp | Certain 1-/dilower-alkyl amino-loweralkyl/-2-phenyl indolizines and quaternary salts thereof |
-
1983
- 1983-01-13 FR FR8300454A patent/FR2539417A1/fr active Granted
-
1984
- 1984-01-10 CS CS84198A patent/CS259516B2/cs unknown
- 1984-01-11 US US06/569,907 patent/US4546100A/en not_active Expired - Lifetime
- 1984-01-11 ZA ZA84234A patent/ZA84234B/xx unknown
- 1984-01-11 NZ NZ206809A patent/NZ206809A/en unknown
- 1984-01-11 DD DD84259352A patent/DD216022A5/de unknown
- 1984-01-11 AU AU23201/84A patent/AU562832B2/en not_active Ceased
- 1984-01-11 GR GR73492A patent/GR81680B/el unknown
- 1984-01-11 IL IL70663A patent/IL70663A/xx unknown
- 1984-01-11 MA MA20223A patent/MA20002A1/fr unknown
- 1984-01-12 FI FI840107A patent/FI76578C/fi not_active IP Right Cessation
- 1984-01-12 BG BG066790A patent/BG40147A3/xx unknown
- 1984-01-12 BG BG063860A patent/BG40968A3/xx unknown
- 1984-01-12 EP EP84400058A patent/EP0118321B1/de not_active Expired
- 1984-01-12 PT PT77951A patent/PT77951B/pt not_active IP Right Cessation
- 1984-01-12 BG BG066789A patent/BG40146A3/xx unknown
- 1984-01-12 IE IE63/84A patent/IE56838B1/en not_active IP Right Cessation
- 1984-01-12 SU SU843692003A patent/SU1297730A3/ru active
- 1984-01-12 BG BG066791A patent/BG40148A3/xx unknown
- 1984-01-12 DK DK13884A patent/DK13884A/da not_active Application Discontinuation
- 1984-01-12 AT AT84400058T patent/ATE24321T1/de not_active IP Right Cessation
- 1984-01-12 NO NO840107A patent/NO167032C/no unknown
- 1984-01-12 KR KR1019840000094A patent/KR910001284B1/ko not_active IP Right Cessation
- 1984-01-12 CA CA000445144A patent/CA1222514A/fr not_active Expired
- 1984-01-12 SU SU843692010A patent/SU1251805A3/ru active
- 1984-01-12 HU HU8481A patent/HU194224B/hu unknown
- 1984-01-12 DE DE8484400058T patent/DE3461713D1/de not_active Expired
- 1984-01-13 PL PL1984245704A patent/PL142322B1/pl unknown
- 1984-01-13 PL PL1984251478A patent/PL144350B1/pl unknown
- 1984-01-13 PL PL1984251479A patent/PL144351B1/pl unknown
- 1984-01-13 ES ES528874A patent/ES8502122A1/es not_active Expired
- 1984-01-13 JP JP59003685A patent/JPS59134797A/ja active Granted
- 1984-01-13 PL PL1984245702A patent/PL144341B1/pl unknown
- 1984-03-28 ES ES531062A patent/ES8504823A1/es not_active Expired
- 1984-03-28 ES ES531063A patent/ES531063A0/es active Granted
- 1984-12-07 SU SU843821204A patent/SU1251808A3/ru active
- 1984-12-14 SU SU843823559A patent/SU1282819A3/ru active
- 1984-12-14 SU SU843822790A patent/SU1277900A3/ru active
- 1984-12-14 SU SU843823253A patent/SU1282818A3/ru active
-
1985
- 1985-04-10 US US06/721,773 patent/US4584297A/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |