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DE3381617D1 - Indazol-derivate. - Google Patents

Indazol-derivate.

Info

Publication number
DE3381617D1
DE3381617D1 DE8383102602T DE3381617T DE3381617D1 DE 3381617 D1 DE3381617 D1 DE 3381617D1 DE 8383102602 T DE8383102602 T DE 8383102602T DE 3381617 T DE3381617 T DE 3381617T DE 3381617 D1 DE3381617 D1 DE 3381617D1
Authority
DE
Germany
Prior art keywords
indazol
derivatives
indazol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8383102602T
Other languages
English (en)
Inventor
Tadayuki Ibuki
Taisuke Sugihara
Hiromu Kawakubo
Takanori Sone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4068982A external-priority patent/JPS58159474A/ja
Priority claimed from JP4068882A external-priority patent/JPS58159473A/ja
Priority claimed from JP4068682A external-priority patent/JPS58159471A/ja
Priority claimed from JP4069182A external-priority patent/JPS58159476A/ja
Priority claimed from JP4069082A external-priority patent/JPS58159475A/ja
Priority claimed from JP4068782A external-priority patent/JPS58159472A/ja
Priority claimed from JP4069282A external-priority patent/JPS58159477A/ja
Application filed by Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Chemical Industry Co Ltd
Application granted granted Critical
Publication of DE3381617D1 publication Critical patent/DE3381617D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8383102602T 1982-03-17 1983-03-16 Indazol-derivate. Expired - Lifetime DE3381617D1 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP4068982A JPS58159474A (ja) 1982-03-17 1982-03-17 新規なベンゼン環置換基を有する１位置換３−アミノインダゾ−ル誘導体およびその製造法
JP4068882A JPS58159473A (ja) 1982-03-17 1982-03-17 ベンゼン環置換基を有する新規な１位置換インダゾ−ル誘導体およびその製造法
JP4068682A JPS58159471A (ja) 1982-03-17 1982-03-17 ベンゼン環置換基を有する新規な１，３位ジ置換３−アミノインダゾ−ル誘導体およびその製造法
JP4069182A JPS58159476A (ja) 1982-03-17 1982-03-17 新規なベンゼン環置換基を有する３位置換インダゾ−ル誘導体およびその製造法
JP4069082A JPS58159475A (ja) 1982-03-17 1982-03-17 ベンゼン環置換基を有する新規な３−アミノインダゾ−ルおよびその製造法
JP4068782A JPS58159472A (ja) 1982-03-17 1982-03-17 ベンゼン環置換基を有する新規な３位置換インダゾ−ル誘導体およびその製造法
JP4069282A JPS58159477A (ja) 1982-03-17 1982-03-17 新規なベンゼン環置換基を有する１，３位ジ置換３−アミノインダゾ−ル誘導体およびその製造法

Publications (1)

Publication Number Publication Date
DE3381617D1 true DE3381617D1 (de) 1990-07-05

Family

ID=27564521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383102602T Expired - Lifetime DE3381617D1 (de) 1982-03-17 1983-03-16 Indazol-derivate.

Country Status (3)

Country Link
US (2) US4533731A (de)
EP (1) EP0090972B1 (de)
DE (1) DE3381617D1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0090972B1 (de) * 1982-03-17 1990-05-30 Asahi Kasei Kogyo Kabushiki Kaisha Indazol-Derivate
JP3462501B2 (ja) * 1992-11-23 2003-11-05 アベンティス・ファーマスーティカルズ・インコーポレイテツド 置換された３−（アミノアルキルアミノ）−１，２−ベンゾイソキサゾールおよび関連化合物
US5494908A (en) * 1992-11-23 1996-02-27 Hoechst-Roussel Pharmaceutical Incorporated Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds
EP0982300A3 (de) * 1998-07-29 2000-03-08 Societe Civile Bioprojet Alkylamine ohne Imidazolring als Histamin-H3-antagonisten und deren therapeutische Anwendung
EP0978512A1 (de) * 1998-07-29 2000-02-09 Societe Civile Bioprojet Aryloxy- (oder Arylthio)alkylamine ohne Imidazolring als Histamin-H3-Antagonisten und deren therapeutische Anwendung
CA2460145C (en) * 2001-09-26 2011-04-26 Pharmacia Italia S.P.A. Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
MXPA05001807A (es) * 2002-09-05 2005-04-19 Aventis Pharma Sa Nuevos derivados de aminoindazol utilizados como medicamentos y composiciones farmaceuticas que los contienen.
BRPI0610580B8 (pt) 2005-05-30 2021-05-25 Banyu Pharma Co Ltd composto derivado de piperidina
US7915410B2 (en) * 2005-09-09 2011-03-29 Bristol-Myers Squibb Company Acyclic IKur inhibitors
NL2012149C2 (nl) * 2013-07-15 2015-01-21 Ind Ontwerpbureau Hsm B V Dispenser en werkwijze voor het dispenseren van tabletten.

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133081A (en) * 1964-05-12 J-aminoindazole derivatives
US2971842A (en) * 1956-03-21 1961-02-14 Gen Aniline & Film Corp Light sensitive layers for photomechanical reproduction
USRE28939E (en) * 1961-11-30 1976-08-24 Smithkline Corporation 3-Aminoindazole derivatives
CH434271A (de) * 1963-01-16 1967-04-30 Siegfried Ag Verfahren zur Herstellung neuer antiphlogistisch wirksamer Aminoindazol-Derivate
US3194020A (en) * 1963-03-25 1965-07-13 Combustion Eng Method and apparatus relating to vapor generation
DE1301319B (de) * 1965-09-08 1969-08-21 Siegfried Ag 3,5-Diaminoindazol, dessen Salze, sowie Verfahren zu deren Herstellung
DE1770649A1 (de) * 1968-06-15 1971-11-11 Bayer Ag Substituierte 3-Amino-indazole
US3681382A (en) * 1969-02-07 1972-08-01 Ciba Geigy Corp 3-aminoindazoles
US3725431A (en) * 1970-09-23 1973-04-03 Ciba Geigy Corp 1-aralkyl-3-aminoindazoles
US3826657A (en) * 1972-02-07 1974-07-30 Tenneco Chem Surface-coating compositions that contain n1-(substituted ethyl)indazoles
CH606334A5 (de) * 1974-06-21 1978-10-31 Ciba Geigy Ag
US4001269A (en) * 1976-01-29 1977-01-04 Morton-Norwich Products, Inc. 3-amino-5,6-dimethoxyindazole hydrochloride
EP0049779B1 (de) * 1980-09-18 1984-10-31 Asahi Kasei Kogyo Kabushiki Kaisha 3-Aminoindazolderivate und Verfahren zu deren Herstellung
EP0090972B1 (de) * 1982-03-17 1990-05-30 Asahi Kasei Kogyo Kabushiki Kaisha Indazol-Derivate

Also Published As

Publication number Publication date
EP0090972A2 (de) 1983-10-12
US4533731A (en) 1985-08-06
US4751302A (en) 1988-06-14
EP0090972B1 (de) 1990-05-30
EP0090972A3 (en) 1984-08-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee