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DD287505A5 - Verfahren zur herstellung von kristallisierten cephem-saeureadditionssalze - Google Patents

Verfahren zur herstellung von kristallisierten cephem-saeureadditionssalze Download PDF

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Publication number
DD287505A5
DD287505A5 DD88313117A DD31311788A DD287505A5 DD 287505 A5 DD287505 A5 DD 287505A5 DD 88313117 A DD88313117 A DD 88313117A DD 31311788 A DD31311788 A DD 31311788A DD 287505 A5 DD287505 A5 DD 287505A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
acid
water
salts
cephem
Prior art date
Application number
DD88313117A
Other languages
German (de)
English (en)
Inventor
Rudolf Lattrell
Walter Duerckheimer
Reiner Kirrstetter
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@������������k�� filed Critical ������@������������k��
Publication of DD287505A5 publication Critical patent/DD287505A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD88313117A 1987-02-25 1988-02-23 Verfahren zur herstellung von kristallisierten cephem-saeureadditionssalze DD287505A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873706020 DE3706020A1 (de) 1987-02-25 1987-02-25 Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DD287505A5 true DD287505A5 (de) 1991-02-28

Family

ID=6321729

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88313117A DD287505A5 (de) 1987-02-25 1988-02-23 Verfahren zur herstellung von kristallisierten cephem-saeureadditionssalze

Country Status (27)

Country Link
US (1) US4845087A (es)
EP (1) EP0280157B1 (es)
JP (1) JP2635078B2 (es)
KR (1) KR960003617B1 (es)
AR (1) AR243193A1 (es)
AT (1) ATE128469T1 (es)
AU (1) AU621040B2 (es)
CA (1) CA1297473C (es)
CS (1) CS274422B2 (es)
CY (1) CY2023A (es)
DD (1) DD287505A5 (es)
DE (2) DE3706020A1 (es)
DK (1) DK174331B1 (es)
ES (1) ES2079349T3 (es)
FI (1) FI91530C (es)
GR (1) GR3017917T3 (es)
HU (1) HU200186B (es)
IE (1) IE69040B1 (es)
IL (1) IL85521A0 (es)
MA (1) MA21193A1 (es)
MX (1) MX10537A (es)
NO (1) NO880811L (es)
NZ (1) NZ223594A (es)
PH (1) PH26857A (es)
PT (1) PT86826B (es)
TN (1) TNSN88018A1 (es)
ZA (1) ZA881282B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4921851A (en) * 1986-06-09 1990-05-01 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
IE61679B1 (en) * 1987-08-10 1994-11-16 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
EP0997466A1 (en) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Novel antimicrobial lactam-quinolones
DE4440141A1 (de) * 1994-11-10 1996-05-15 Hoechst Ag Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
KR100389284B1 (ko) * 1999-09-30 2003-06-27 (주)정인종합건축사사무소 경첩
ES2346573T3 (es) * 2005-10-29 2010-10-18 Intervet International Bv Composiciones de cefquinoma y metodos para su uso.
TWI400243B (zh) * 2009-07-20 2013-07-01 Intervet Int Bv 製造西喹諾(cefquinome)粒子的方法
CN102002058B (zh) * 2010-11-05 2012-04-04 山东鲁抗立科药物化学有限公司 硫酸头孢喹肟的合成方法
WO2012095438A1 (en) 2011-01-12 2012-07-19 Intervet International B.V. Particles and suspensions of cephalosporin antibiotics
CN104031069B (zh) * 2014-05-19 2016-05-18 浙江工业大学 一种硫酸头孢喹肟的制备方法
CN111072686B (zh) * 2019-12-30 2021-02-12 济宁市化工研究院(淮海化工研究院) 一种硫酸头孢喹肟的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005439A (nl) * 1979-10-02 1981-04-06 Glaxo Group Ltd Verbeteringen aan of met betrekking tot een cefalosporine met antibiotische werking.
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
DE3419015A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von cephalosporinen

Also Published As

Publication number Publication date
AU1210688A (en) 1988-09-01
US4845087A (en) 1989-07-04
EP0280157B1 (de) 1995-09-27
HUT46695A (en) 1988-11-28
JPH01216995A (ja) 1989-08-30
FI880842A0 (fi) 1988-02-23
AR243193A1 (es) 1993-07-30
NO880811D0 (no) 1988-02-24
NZ223594A (en) 1990-03-27
CS274422B2 (en) 1991-04-11
FI91530B (fi) 1994-03-31
CS113688A2 (en) 1990-08-14
IE69040B1 (en) 1996-08-07
KR960003617B1 (en) 1996-03-20
JP2635078B2 (ja) 1997-07-30
FI91530C (fi) 1994-07-11
ATE128469T1 (de) 1995-10-15
FI880842A (fi) 1988-08-26
CY2023A (en) 1998-02-20
PT86826A (pt) 1988-03-01
HU200186B (en) 1990-04-28
GR3017917T3 (en) 1996-01-31
DK95788D0 (da) 1988-02-24
ES2079349T3 (es) 1996-01-16
DK174331B1 (da) 2002-12-09
EP0280157A3 (en) 1990-07-18
AU621040B2 (en) 1992-03-05
PT86826B (pt) 1992-05-29
MA21193A1 (fr) 1988-10-01
DE3706020A1 (de) 1988-09-08
DE3854507D1 (de) 1995-11-02
CA1297473C (en) 1992-03-17
EP0280157A2 (de) 1988-08-31
ZA881282B (en) 1988-08-23
NO880811L (no) 1988-08-26
PH26857A (en) 1992-11-16
IL85521A0 (en) 1988-08-31
DK95788A (da) 1988-08-26
IE880503L (en) 1988-08-25
KR880009973A (ko) 1988-10-06
MX10537A (es) 1993-08-01
TNSN88018A1 (fr) 1990-07-10

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Legal Events

Date Code Title Description
RPI Change in the person, name or address of the patentee (searches according to art. 11 and 12 extension act)
ASS Change of applicant or owner

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH, FRANKFURT

Effective date: 20000519

IF04 In force in the year 2004

Expiry date: 20080224