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DD283381A5 - Verfahren zur herstellung einer verbindung - Google Patents

Verfahren zur herstellung einer verbindung Download PDF

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Publication number
DD283381A5
DD283381A5 DD88323142A DD32314288A DD283381A5 DD 283381 A5 DD283381 A5 DD 283381A5 DD 88323142 A DD88323142 A DD 88323142A DD 32314288 A DD32314288 A DD 32314288A DD 283381 A5 DD283381 A5 DD 283381A5
Authority
DD
German Democratic Republic
Prior art keywords
alkyl
cyclohexyl
hydrogen
compounds
mmol
Prior art date
Application number
DD88323142A
Other languages
German (de)
English (en)
Inventor
Robert L Rosati
Original Assignee
������@���Kk��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD283381A5 publication Critical patent/DD283381A5/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Fodder In General (AREA)
  • Cosmetics (AREA)
DD88323142A 1987-12-15 1988-12-14 Verfahren zur herstellung einer verbindung DD283381A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13237387A 1987-12-15 1987-12-15

Publications (1)

Publication Number Publication Date
DD283381A5 true DD283381A5 (de) 1990-10-10

Family

ID=22453720

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88323142A DD283381A5 (de) 1987-12-15 1988-12-14 Verfahren zur herstellung einer verbindung

Country Status (27)

Country Link
EP (1) EP0321192B1 (fi)
JP (1) JPH0692366B2 (fi)
KR (1) KR900009022B1 (fi)
CN (1) CN1025676C (fi)
AT (1) ATE96433T1 (fi)
AU (1) AU593181B2 (fi)
CA (1) CA1314545C (fi)
CS (1) CS274671B2 (fi)
DD (1) DD283381A5 (fi)
DE (1) DE3885252T2 (fi)
DK (1) DK694888A (fi)
EG (1) EG18927A (fi)
ES (1) ES2059540T3 (fi)
FI (1) FI88295C (fi)
HU (1) HU201564B (fi)
IE (1) IE61548B1 (fi)
IL (1) IL88619A0 (fi)
MX (1) MX14210A (fi)
MY (1) MY104354A (fi)
NO (1) NO172935C (fi)
NZ (1) NZ227322A (fi)
PH (1) PH26974A (fi)
PL (1) PL152507B1 (fi)
PT (1) PT89210B (fi)
SU (1) SU1651786A3 (fi)
YU (1) YU46686B (fi)
ZA (1) ZA889307B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2638747B1 (fr) * 1988-11-08 1993-12-24 Synthelabo Derives de phenyloxypropanolamines, leur preparation et leur application en therapeutique
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
DE4035846A1 (de) * 1990-11-10 1991-06-06 Kuntze Angelgeraete Dam Angelrolle mit spule zur aufnahme der angelschnur
JP3771591B2 (ja) 1997-02-26 2006-04-26 ファイザー・インク ヘテロアリールヘキサン酸アミド誘導体、それらの製造法およびそのCCR1レセプターと結合するMIP−1αの選択的な阻害剤としてのそれらの使用
EP1498417A1 (en) * 2000-02-04 2005-01-19 Pfizer Products Inc. Heterocyclic amide derivatives
EA200401099A1 (ru) * 2000-02-04 2005-02-24 Пфайзер Продактс Инк. Производные гетероциклического амида
US20040097554A1 (en) * 2002-10-30 2004-05-20 Pfizer Inc Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents
US7405210B2 (en) 2003-05-21 2008-07-29 Osi Pharmaceuticals, Inc. Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
UA84146C2 (ru) * 2003-05-21 2008-09-25 Прозидион Лимитед Амиды пирролопиридин-2-карбоновой кислоты как ингибиторы гликогенфосфорилазы, способ их получения, фармацевтическая композиция и их применение как терапевтических агентов для лечения заболеваний
CN108218865B (zh) * 2018-03-31 2020-06-26 济南市儿童医院 一种酰胺类衍生物及其在心脑血管方面的应用
CN108456207B (zh) * 2018-03-31 2020-11-20 浙江药苑生物科技有限公司 一种酰胺类衍生物及其在心脑血管方面的应用
CN108164528B (zh) * 2018-03-31 2019-03-22 杭州巴洛特生物科技有限公司 一种酰胺类衍生物及其在高血压、高血脂和动脉粥样硬化中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0181110A3 (en) * 1984-10-22 1988-05-11 Kissei Pharmaceutical Co. Ltd. Histidine derivatives as renin inhibitors
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives

Also Published As

Publication number Publication date
EP0321192A2 (en) 1989-06-21
YU225788A (en) 1990-04-30
YU46686B (sh) 1994-04-05
CS274671B2 (en) 1991-09-15
HU201564B (en) 1990-11-28
ZA889307B (en) 1990-08-29
NO885549L (no) 1989-06-16
NO172935C (no) 1993-09-29
KR900009022B1 (ko) 1990-12-17
DK694888A (da) 1989-08-11
CS820388A2 (en) 1990-10-12
NZ227322A (en) 1990-06-26
MX14210A (es) 1993-05-01
EG18927A (en) 1996-03-31
ES2059540T3 (es) 1994-11-16
PL276363A1 (en) 1989-08-07
DK694888D0 (da) 1988-12-14
FI885783A0 (fi) 1988-12-14
EP0321192B1 (en) 1993-10-27
IE883731L (en) 1989-06-15
IE61548B1 (en) 1994-11-16
PT89210B (pt) 1993-09-30
FI885783A (fi) 1989-06-16
AU593181B2 (en) 1990-02-01
NO885549D0 (no) 1988-12-14
PT89210A (pt) 1989-12-29
PH26974A (en) 1992-12-28
FI88295B (fi) 1993-01-15
AU2688188A (en) 1989-06-15
NO172935B (no) 1993-06-21
HUT48277A (en) 1989-05-29
ATE96433T1 (de) 1993-11-15
SU1651786A3 (ru) 1991-05-23
CN1025676C (zh) 1994-08-17
FI88295C (fi) 1993-04-26
DE3885252T2 (de) 1994-02-17
JPH0692366B2 (ja) 1994-11-16
CA1314545C (en) 1993-03-16
IL88619A0 (en) 1989-07-31
DE3885252D1 (de) 1993-12-02
CN1034366A (zh) 1989-08-02
EP0321192A3 (en) 1991-01-30
PL152507B1 (en) 1991-01-31
KR890009867A (ko) 1989-08-04
MY104354A (en) 1994-03-31
JPH01250345A (ja) 1989-10-05

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