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CY1115589T1 - Φαρμακευτικες συνθεσεις για την προληψη και αγωγη των διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας μια νικοτινικη ενωση και εναν αναστολεα ακετυλχολινεστερασης - Google Patents

Φαρμακευτικες συνθεσεις για την προληψη και αγωγη των διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας μια νικοτινικη ενωση και εναν αναστολεα ακετυλχολινεστερασης

Info

Publication number
CY1115589T1
CY1115589T1 CY20141100777T CY141100777T CY1115589T1 CY 1115589 T1 CY1115589 T1 CY 1115589T1 CY 20141100777 T CY20141100777 T CY 20141100777T CY 141100777 T CY141100777 T CY 141100777T CY 1115589 T1 CY1115589 T1 CY 1115589T1
Authority
CY
Cyprus
Prior art keywords
nicotinic
enhancer
prevention
treatment
pharmaceutical compositions
Prior art date
Application number
CY20141100777T
Other languages
English (en)
Inventor
Marouane Bencherif
Original Assignee
Targacept, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Targacept, Inc. filed Critical Targacept, Inc.
Publication of CY1115589T1 publication Critical patent/CY1115589T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Μια φαρμακευτική σύνθεση περιλαμβάνοντας μία φαρμακευτικώς αποτελεσματική ποσότητα δύο τουλάχιστον συστατικών, ένα από εκείνα τα συστατικά όντας ένας νικοτινικός αγωνιστής και ένα από εκείνα τα συστατικά όντας ένας αναστολέας ακετυλχολινεστεράσης, όπου ο αναστολέας ακετυλχολινεστεράσης είναι η δονεπεζίλη.
CY20141100777T 1998-08-07 2014-09-24 Φαρμακευτικες συνθεσεις για την προληψη και αγωγη των διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας μια νικοτινικη ενωση και εναν αναστολεα ακετυλχολινεστερασης CY1115589T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/130,498 US6218383B1 (en) 1998-08-07 1998-08-07 Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
EP08019914.4A EP2018874B1 (en) 1998-08-07 1999-06-02 Pharmaceutical compositions for the prevention and treatment of central nervous system disorders comprising a nicotinic agonist and an acetylcholinesterase inhibitor

Publications (1)

Publication Number Publication Date
CY1115589T1 true CY1115589T1 (el) 2017-01-04

Family

ID=22444976

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20091100150T CY1110309T1 (el) 1998-08-07 2009-02-10 Φαρμακευτικες συνθεσεις για την προληψη και την αγωγη διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας ενα αναλογο νικοτινης και εναν αναστολεα ακετυλχολινεστερασης
CY20141100777T CY1115589T1 (el) 1998-08-07 2014-09-24 Φαρμακευτικες συνθεσεις για την προληψη και αγωγη των διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας μια νικοτινικη ενωση και εναν αναστολεα ακετυλχολινεστερασης

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20091100150T CY1110309T1 (el) 1998-08-07 2009-02-10 Φαρμακευτικες συνθεσεις για την προληψη και την αγωγη διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας ενα αναλογο νικοτινης και εναν αναστολεα ακετυλχολινεστερασης

Country Status (16)

Country Link
US (1) US6218383B1 (el)
EP (2) EP1102588B1 (el)
JP (2) JP4750945B2 (el)
KR (1) KR100705434B1 (el)
AT (1) ATE418986T1 (el)
AU (1) AU761087B2 (el)
BR (1) BR9912805A (el)
CA (1) CA2335012C (el)
CY (2) CY1110309T1 (el)
DE (1) DE69940199D1 (el)
DK (2) DK2018874T3 (el)
ES (2) ES2322725T3 (el)
HK (1) HK1127290A1 (el)
MX (1) MXPA01001435A (el)
PT (2) PT2018874E (el)
WO (1) WO2000007600A1 (el)

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PT2018874E (pt) 2014-10-16
JP4750945B2 (ja) 2011-08-17
MXPA01001435A (es) 2003-09-10
CA2335012C (en) 2009-08-11
ES2322725T3 (es) 2009-06-25
CA2335012A1 (en) 2000-02-17
US6218383B1 (en) 2001-04-17
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DE69940199D1 (de) 2009-02-12
CY1110309T1 (el) 2015-01-14
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EP1102588A1 (en) 2001-05-30
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EP2018874A2 (en) 2009-01-28
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